web2.0 & bioinformatics

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  • 1. Web2.0 Bioinformatics
    • Hong Chang Bum
  • [email_address]

2. Ruby on Rails 3. Ruby on Rails (Ruby on Rails) : (Framework) MVC MVC(Model View Controller) : , : 4. 1 5. Web2.0Bioinformatics Mash-up 6. ? . . . 7. Bioinformatics OpenAPI EBI http:// www.ebi.ac.uk/Tools/webservice/ NCBI http://eutils.ncbi.nlm.nih.gov/ entrez/query/static/eutils_help.html DDBJ http://xml.ddbj.nig.ac.jp /soapp.html 8. 9. ( , , ) + OpenAPI = Mash-up 10. 11. + OpenAPI = Mash-up 12. 13. ( Drosophila melanogaster ) >gi|24638702|ref|NP_524628.2| eyeless CG1464-PA, isoform A [Drosophila melanogaster] MFTLQPTPTAIGTVVPPWSAGTLIERLPSLEDMAHKGHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGA RPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLL QENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSS STDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSS HPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESL ASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTN DQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSS TSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPS CTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHT ALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPA GVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSASANVTPHHTIAQESCPSPCS SASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSASGTSAHVAPGKQQFFASCFYSPWV >gi|4505615|ref|NP_000271.1| paired box gene 6 isoform a [Homo sapiens] MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRA IGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGAD GMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKL QRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASN TPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQ TSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPR LQ eyless aniridia 14. Score =252 bits (644),Expect = 1e-64 Identities = 124/132 (93%), Positives = 128/132 (96%), Gaps = 0/132 (0%) Query38HSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETG97 HSGVNQLGGVFV GRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETG Sbjct5HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETG64 Query98SIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSIN157 SIRPRAIGGSKPRVAT EVVSKI+QYKRECPSIFAWEIRDRLL E VCTNDNIPSVSSIN Sbjct65SIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSIN124 Query158RVLRNLAAQKEQ169 RVLRNLA++K+Q Sbjct125RVLRNLASEKQQ136 15. Thank u ^^