NewVac, ltd A pioneer of innovative

oncoimmunology, personalized medicine and combinational therapy

More than 8 million death cases per year

According to WHO USA, Western Europe, India, China and Russia are the countries with the highest incidence of cancer

World market of the anticancer medicine exceeded $50 billion in 2010, including $1 billion of the Russian market

CAGR of anticancer drugs market is 12-15%

CANCER – PROBLEM WE SOLVE

WHAT WE DO

Personalized medicineDevelopment and commercialization of cell based vaccine therapy and

diagnostics

Development of new standards of treatment

Combinational cancer therapyAdjuvants+ vaccines

Targeted therapy+ vaccines

Targeted therapy+ radio- and chemotherapy

GMP manufacturingPersonalized vaccines, cell therapy and diagnostics

OUR CANCER DRUG PIPELINE

Oncophage adjuvant therapy for renal cell carcinoma

Oncophageadjuvant therapy for ovarian cancer

Oncophage + Votrientmetastatic renal cell carcinoma

Quisinostat + SOC

non-small cell lung cancer, ovarian cancer

Dendritic cell vaccine + А2А

disseminated melanoma

А2А:new

antagonists

Pre-clinical Phase I Phase II Phase III Market

UNIQUE GMP FACILITY FOR PERSONALIZED VACCINES

Production of a wide range of personalized vaccine for anticancer therapy (protein, dendritic cell-based etc.) and injection forms for the treatment and clinical research

• 09’2012 – 11’2012 staff training on Agenus GMP manufacture in Boston, USA

• 12’2012 –02’2013 development of manufacturing regulations and the acceptance of quality assurance system

• 03’2013 – licensing of the production in the Ministry of industry and trade

• 06’2013 - start of the contract manufacturing of vaccines for clinical trials (3 preliminary agreements)

• 11’2013 – manufacturing of the first product for the patient treatment

OUR TEAM

Igor Orshanskiy,

CEO

PhD, 8 years of biotech and pharma project management

Sergey Dudkin,

Strategy director

MD, 15-years marketing experience at BigPharma companies

Andrey Golubev,

Medical director

MD, 11-years medical advisor experience at BigPharma companies

Ilya Kazeev,

Manufacturing director

PhD, 11-years experience in manufacturing at biotech companies

WHAT WE SEEK

• Clinical trials, registration and promotion of new products

INVESTORS FOR

• Pipeline extension• Collaboration in drug localization and market access

PARTNERS FOR

• Contract manufacturing of innovative vaccines and cell products

CLIENTS FOR

COMPANY OF A NEW TYPE

The specializedresearch-and-production pharmaceutical company

for development and commercialization of

personalized medicine methods for prophylaxis, diagnostics and treatment

of cancer.