dr. zahoor 1. blood plasma hematocrit or pcv plasma protein erythropoiesis anaemia white...

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HMIM - 224 TUTORIAL - I DISCUSSION

Dr. Zahoor

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Blood Plasma Hematocrit or PCV Plasma Protein Erythropoiesis Anaemia White Blood Cell (WBC)

Topics

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Q.1 Give the composition of blood?

Q2. Define Hematocrit or PCV.

Q3. In blood, how much % is plasma?

Q4. What is the composition of plasma?

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Q5. Name the plasma protein.

Q6. What is the function of albumin?

Q7. What is the function of Globulin (alpha

and beta)?

Q8. What is gamma globulin?

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Q9. What is the function of different gamma

globulins?

Q10. What is the function of fibrinogen?

Q11. Give the causes of hypoprotenemia?

Q12. What is edema? What is the cause of

edema?

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Q13. Blood viscosity depends on what?

Q14. How much blood volume in normal adult

male/female?

Q15. What is life span of RBC?

Q16. What is the difference between blood,

plasma and serum?

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Q17. What is normal RBC count?

Q18. What is the size of RBC and its shape?

Q19. What is the function of RBC?

Q20. Why RBC is red?

Q21. What is the composition of hemoglobin?

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Q22. If you see arterial blood and venous blood

sample in the tube by naked eye, what difference in

the color would you find?

Q23. In adult, where erythropoiesis takes place?

Q24. What things are required for erythropoiesis?

Q25. What is the difference between red and yellow

bone marrow?

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Q26. In your hospital, you are asked to take the

bone marrow sample of a patient who has

decreased RBC, WBC, and platelet count, which site

you will choose to take the bone marrow sample?

Q27. What is erythropoietin?

Q28. Where is erythropoietin formed?

Q29. What is the function of Erythropoietin?

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Q30. A patient has kidney disease, what will be his

hemoglobin, and RBC count? What treatment you

will give him/her for his anemia?

Q31. If reticulocyte count is increased, what does

it signify?

Q32. When there is Hb breakdown, what happens?

Q33. What is Anemia?

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Q34. What are different types of Anemia?

Q35. If Hb decreased, RBC decreased, PCV

decreased, MCV decreased, MCH decreased,

what type of anemia is it?

Q36. What will happen in Vit B12 deficiency

anemia?

Q37. Define MCH.

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Q38. How much is normal Hb in adult person?

Q39. Give two causes of Hemolytic anemia?

Q40. Give two causes of Aplastic anemia?

Q41. How much blood is taken when blood donation

is done?

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Q42.After how much time, blood donation

can be given again, why?

Q43. What are different types of WBC?

Q44. What is normal % of N, E, B, L, M? What

is life span of different leukocytes?

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Q45. How you will identify neutrophil in

microscopic examination?

Q46. What is function of

Neutrophil

Eosinophil

Basophil

Lymphocyte

Monocyte

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Q47. What is normal total leukocyte count?

Q48. What is Leukocytosis?

Q49. In what condition, Leukocytosis will occur.

Q50.What is Leukopenia. Give one cause.

Q51. What is Leukemia?

Case History A 35 year old, businessman consults his

physician complaining of passing black stools for the last 2 weeks. He had a history of abdominal pain (epigastric region) for the last one year. He had been relieving this pain by taking tablets off and on. In the past week the patient noticed that he became breathless (dyspneic) on exertion.

Case History cont… Upon examination the patient looked pale.

The pallor is most obvious in the conjunctivae and the nail beds. His heart rate was 105 beats/ minutes at rest (slightly raised) and there is tenderness on palpation of the epigastrium. Stool examined by naked eye looked black (malena). Laboratory test was positive for blood in the stool.

Case summary A patient looks pale, with history of dyspnea

on exertion, slightly increased heart rate and the presence of blood in the stool, the following blood test were ordered.

1. RBC count, 2. hemoglobin concentration and 3. hematocrit.

RBC count Hemoglobin concentration Hematocrit

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Write the expected results

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1. Define anemia.

What type of anemia do you suspect in this case ?

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2. In iron deficiency anemia, how the RBCs look like on a blood film?

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3. What do the words microcytic and hypochromic means?

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4. Where is the iron absorbed?

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6. In this patient why was the stool colored black?

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Thank you