dr. zahoor 1. blood plasma hematocrit or pcv plasma protein erythropoiesis anaemia white...

26
HMIM - 224 TUTORIAL - I DISCUSSION Dr. Zahoor 1

Upload: tracy-sherman

Post on 29-Jan-2016

223 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

1

HMIM - 224 TUTORIAL - I DISCUSSION

Dr. Zahoor

Page 2: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

2

Blood Plasma Hematocrit or PCV Plasma Protein Erythropoiesis Anaemia White Blood Cell (WBC)

Topics

Page 3: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

3

Q.1 Give the composition of blood?

Q2. Define Hematocrit or PCV.

Q3. In blood, how much % is plasma?

Q4. What is the composition of plasma?

Page 4: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

4

Q5. Name the plasma protein.

Q6. What is the function of albumin?

Q7. What is the function of Globulin (alpha

and beta)?

Q8. What is gamma globulin?

Page 5: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

5

Q9. What is the function of different gamma

globulins?

Q10. What is the function of fibrinogen?

Q11. Give the causes of hypoprotenemia?

Q12. What is edema? What is the cause of

edema?

Page 6: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

6

Q13. Blood viscosity depends on what?

Q14. How much blood volume in normal adult

male/female?

Q15. What is life span of RBC?

Q16. What is the difference between blood,

plasma and serum?

Page 7: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

7

Q17. What is normal RBC count?

Q18. What is the size of RBC and its shape?

Q19. What is the function of RBC?

Q20. Why RBC is red?

Q21. What is the composition of hemoglobin?

Page 8: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

8

Q22. If you see arterial blood and venous blood

sample in the tube by naked eye, what difference in

the color would you find?

Q23. In adult, where erythropoiesis takes place?

Q24. What things are required for erythropoiesis?

Q25. What is the difference between red and yellow

bone marrow?

Page 9: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

9

Q26. In your hospital, you are asked to take the

bone marrow sample of a patient who has

decreased RBC, WBC, and platelet count, which site

you will choose to take the bone marrow sample?

Q27. What is erythropoietin?

Q28. Where is erythropoietin formed?

Q29. What is the function of Erythropoietin?

Page 10: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

10

Q30. A patient has kidney disease, what will be his

hemoglobin, and RBC count? What treatment you

will give him/her for his anemia?

Q31. If reticulocyte count is increased, what does

it signify?

Q32. When there is Hb breakdown, what happens?

Q33. What is Anemia?

Page 11: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

11

Q34. What are different types of Anemia?

Q35. If Hb decreased, RBC decreased, PCV

decreased, MCV decreased, MCH decreased,

what type of anemia is it?

Q36. What will happen in Vit B12 deficiency

anemia?

Q37. Define MCH.

Page 12: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

12

Q38. How much is normal Hb in adult person?

Q39. Give two causes of Hemolytic anemia?

Q40. Give two causes of Aplastic anemia?

Q41. How much blood is taken when blood donation

is done?

Page 13: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

13

Q42.After how much time, blood donation

can be given again, why?

Q43. What are different types of WBC?

Q44. What is normal % of N, E, B, L, M? What

is life span of different leukocytes?

Page 14: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

14

Q45. How you will identify neutrophil in

microscopic examination?

Q46. What is function of

Neutrophil

Eosinophil

Basophil

Lymphocyte

Monocyte

Page 15: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

15

Q47. What is normal total leukocyte count?

Q48. What is Leukocytosis?

Q49. In what condition, Leukocytosis will occur.

Q50.What is Leukopenia. Give one cause.

Q51. What is Leukemia?

Page 16: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

Case History A 35 year old, businessman consults his

physician complaining of passing black stools for the last 2 weeks. He had a history of abdominal pain (epigastric region) for the last one year. He had been relieving this pain by taking tablets off and on. In the past week the patient noticed that he became breathless (dyspneic) on exertion.

Page 17: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

Case History cont… Upon examination the patient looked pale.

The pallor is most obvious in the conjunctivae and the nail beds. His heart rate was 105 beats/ minutes at rest (slightly raised) and there is tenderness on palpation of the epigastrium. Stool examined by naked eye looked black (malena). Laboratory test was positive for blood in the stool.

Page 18: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

Case summary A patient looks pale, with history of dyspnea

on exertion, slightly increased heart rate and the presence of blood in the stool, the following blood test were ordered.

1. RBC count, 2. hemoglobin concentration and 3. hematocrit.

Page 19: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

RBC count Hemoglobin concentration Hematocrit

19

Write the expected results

Page 20: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

20

1. Define anemia.

Page 21: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

What type of anemia do you suspect in this case ?

Page 22: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

22

2. In iron deficiency anemia, how the RBCs look like on a blood film?

Page 23: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

23

3. What do the words microcytic and hypochromic means?

Page 24: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

24

4. Where is the iron absorbed?

Page 25: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

25

6. In this patient why was the stool colored black?

Page 26: Dr. Zahoor 1.  Blood  Plasma  Hematocrit or PCV  Plasma Protein  Erythropoiesis  Anaemia  White Blood Cell (WBC) 2

26

Thank you