canœrresearch*4916 augmentation of cytotoxicity of chemotherapy by human
TRANSCRIPT
CanœrResearchVOLUME 46 •NUMBER 10 •CNREA8 •PP 4879-5455
CONTENTSf
Asterisks * preceding page numbers refer to studies using human-derived material.
Perspectives in Cancer Research
4879 0-Alkyl Pyrimidines in Mutagenesis and Carcinogenesis: Occurrence and Significance. B. Singer.
BASIC SCIENCES
* 488ft Preclinical Trials with Combinations and Conjugates of T101Monoclonal Antibody and Doxorubicin. Roben O. Dillman,Daniel L. Shawler, Duane E. Johnson, Damon L. Meyer, JamesA. Koziol and James M. Frincke.
* 4892 Comparison of the Cytotoxic Effects of Merocyanine-540 on Leu-kemic Cells and Normal Human Bone Marrow. Jens Atzpodien,Subhash C. Gulati and Bayard D. Clarkson.
#48% Hypoxanthine:Guanine Phosphoribosyltransferase Activity inXenografts of Human Osteosarcoma. William H. Meyer, Janet A.Houghton, Pamela J. Lutz and Peter J. Houghton.
* 4<)(MI Identification of Metabolites of the Cell-differentiating AgentHexamethylene Bisacetamide in Humans. Patrick S. Callen,Merrill J. Egorin, Linda A. Geelhaar and M. S. BalachandranNayar.
* 4904 Antibody-directed Liposomes: Comparison of Various Ligands forAssociation, Endocytosis, and Drug Delivery. Katherine K.Matthay, Timothy D. Heath, Christopher C. Badger, Irwin D.Bernstein and Demetrios Papahadjopoulos.
4911 Tumorigènesis and Genotoxicity of Ethyl Carbamate and VinylCarbamate in Rodent Cells. James W. Allen, Gary D. Stoner,Michael A. Pereira, Lorraine C. Backer, Yousuf Sharief, GeorgeG. Hatch, James A. Campbell, Andrew G. Stead and StephenNesnow.
*4916 Augmentation of Cytotoxicity of Chemotherapy by Human <»-Interferons in Human Non-Small Cell Lung Cancer Xenografts.James Carmichael, Ronald J. Fergusson, C. Roland Wolf, FrancesR. Balkwill and John F. Smyth.
4921 Comparison of the Tumor-associated Transplantation Antigens ofSublines of Methylcholanthrene-induced Murine Tumors Passaged Separately in Vivo for over a Decade. David L. Hiñes.
:'c4927 Effects of Glucocorticoids on the Growth of Human FibrosarcomaCell Line HT-1080. Michael J. Walker, Custodio Lim, Tapas K.Das Gupta and Craig W. Beattie.
*4933 Stimulation of Cell Proliferation and Estrogenic Response byAdrenal C,,-A5-Steroids in the ZR-75-1 Human Breast Cancer
Cell Line. Richard Poulin and Fernand Labrie.
4938 Polyamines and Hormonal Regulation of W-Nitrosomethylurea-induced Rat Mammary Tumor Growth in Vivo. Andrea Manni,Carol Wright, Lawrence Demers and Gordon Luk.
* 4942 Interspecies Comparison of Human and Rat Mammary EpithelialCell-mediated Mutagenesis by Polycyclic Aromatic Hydrocarbons. Michael N. Gould, Dorene R. Grau, Lisa A. Seidman andCynthia J. Moore.
4953
4960
4966
4971
4973
* 4979
* 4984
4991
*4<W5
* 4999
5004
*5009
* 5014
Interspecies Comparison of Polycyclic Aromatic HydrocarbonMetabolism in Human and Rat Mammary Epithelial Cells.Cynthia J. Moore, William A. Tricomi and Michael N. Gould.
Modulation of B16 Melanoma Antigen Expression by Lympho-kines and Dimethyl Sulfoxide. Kevin L. Trimpe and Bruce S.Zwilling.
Correlation of Biochemical Effects and Incorporation of 3-De-azaguanine into Nucleic Acids to Cytotoxicity in LI 210 Cells.Russell O. Pieper, Louis R. Barrows and H. George Mandel.
Treatment of Experimental Lung Metastasis with Local ThoracicIrradiation Followed by Systemic Macrophage Activation withLiposomes Containing Muramyl Tripeptide. Ikuo Saiki, LukaMilas, Nancy Hunter and Isaiah J. Fidler.
Paradoxical Effect of Three-Day Thymectomy on Sarcogenesis inthe Mouse with Different Dosages of Methylcholanthrene. LiisaM. Prehn and Akinori Kojima.
Amitumor Efficacy of Lymphokine-activated Killer Cells andRecombinant Interleukin 2 in Vivo:Successful ImmunotherapyofEstablished Pulmonary Métastasesfrom Weakly Immunogenicand Nonimmunogenic Murine Tumors of Three Distinct 11istologie-ai Types. Moshe Z. Papa, James J. Muléand Steven A.
Rosenberg.
Effects of Calcitriol on Nuclear Transcription during Human III-60 Promyelocytic Leukemia Cell Differentiation. Emery H.Bresnick and Robert U. Simpson.
Differential Effects of RecombinantHuman Leukocyte Interferonson Cell Surface Antigen Expression. John W. Greiner, Paul B.Fisher, Sidney Pestka and Jeffrey Schlom.
In Vivo Generation of Tumor-specific Cytotoxic T-Cells in theRegional Lymph Node: Effect of Subcutaneous Inoculationof mis-disparate Spleen Cells aroundImplantedTumors in Mice. MilioniHigasa, Kazuhiko Yamada, Yutaka Takagaki, Masahiro Aoki,Sohei Shinka and Yoshitane Dohi.
Combined Effects of Streptozotocin and Mitozolomide againstFour Human Cell Lines of the Mer* Phenotype. Neil W. Gibson,
John A. Hartley, Diane Barnes and Leonard C. Erickson.
Differential Cytotoxicity and DNA-damaging Effects Produced inHuman Cells of the Mer* and Mor Phenotypes by a Series of I-Aryl-3-alkyltriazenes. Neil W. Gibson, John A. Hartley, RonaldJ. LaFrance and Keith Vaughan.
Inductionof Tumor Immunityand Natural Killer Cell Cytotoxicityin Mice by 5-Halo-6-phenyl Pyrimidinone. Eva Lotzová,C. A.Savary, S. Pollack and N. Hanna.
Cross-Sensitivity of Methylating Agents, Hydroxyurea, andMethotrexate in Human Tumor Cells of the Mer" Phenotype.
Kevin Maynard and Peter G. Parsons.
Mechanism of Action of the Novel Anticancer Agent 6-Fluoro-2-(2 ' - fluoro-l,l'-biphenyl-4-yl)-3-methyl-4- quinolinecarboxylie
Acid Sodium Salt (NSC 368390): Inhibitionof de Novo PyrimidineNucleotide Biosynthesis. Shih-Fong Chen, Regina L. Ruben andDaniel L. Dexter.
t The CONTENTS arranged by Subject Category can be found immediately following these CONTENTS.
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
5020 Interaction of Polyglutamyl Derivatives of Methotrexate, 10-De-azaaminopterin, and Dihydrofolate with Dihydrofolate ReducÃase.Piyush Kumar, Roy L. Kisliuk, Yvette Gaumont, Madhavan G.Nair, Charles M. Baugh and Bernard T. Kaufman.
* 5024 Demonstration of Epstein-Barr Virus-specific DNA Polymerase
in Chemically Induced Raji Cells and Its Antibody in Serum fromPatients with Nasopharyngeal Carcinoma. Run-sheng Tan, Jin-sen Li, Susan P. Grill, Louise M. Nutter and Yung-chi Cheng.
:':5029 Cytotoxicity, DNA Cross-Linking, and Single Strand Breaks In
duced by Activated Cyclophosphamide and Acrolein in HumanLeukemia Cells. Tim R. Crook, Robert L. Souhami and AndréE. M. McLean.
* 5035 Glutathione Depletion as a Determinant of Sensitivity of Human
Leukemia Cells to Cyclophosphamide. Tim R. Crook, Robert L.Souhami. Gillian D. Whyman and A. E. M. McLean.
"'•5039 Lack of Production of Interleukin 1 by Human Blood Monocytes
Activated to the Antitumor State by Liposome-encapsulated Mur-amyl Tripeptide. Priti Tandon, Teruhiro Utsugi and Saburo Soné.
5045 Detection of a Polyoma Virus-induced Tumor-associated Membrane Antigen in Mouse Cells by the Macrophage MigrationInhibition Test. Torbjörn Ramqvist, Tina Dalianis, GitReinholdsson, George Klein and Robert Szigeti.
5049 Complete Regression of Mouse Hepatoma Transplanted afterPartial Hepatectomy and the Immunological Mechanism of SuchRegression. Minoru Ono, Noriaki Tanaka and Kunzo Onta.
*5054 Modulation of the Antitumor and Biochemical Properties ofBis(diphenylphosphine)ethane with Metals. Rosanne M. Snyder,Christopher K. Mirabelli, Randall K. Johnson, Chiù-Mei Sung,Leo F. Faucette, Francis L. McCabe, Joseph P. Zimmerman,Matthew Whitman, Judith C. Hempel and Stanley T. Crooke.
*>()(>I Effects of Thromboxane A2 Inhibition on Osteogenic SarcomaCell-induced Platelet Aggregation. Paulette Mehta, DanielLawson, Mary Beth Ward, Linda Lee-Ambrose and ArthurKimura.
5064 Dansyl Lysine, a New Probe for Assaying Heat-induced CellKilling and Thermotolerance in Vitro and in Vivo.George Fisher,Glenn C. Rice and George M. Hahn.
5068 Activation of the Colon Carcinogen 1,2-Dimethylhydrazine in aRat Colon Cell-mediated Mutagenesis Assay. Carol T. Oravec,Carol A. Jones and Eliezer Huberman.
5072 Effects of Neonatal and Adult Castration on the in Vitro Metabolism of Steroids and Xenobiotics in Rat Liver. Agneta Blanck,Anders Aströmand Tiiu Hansson.
:': 5077 Macrophage Tumoricidal Activity Induced by Human C-Reactive
Protein. Kamyar Zahedi and Richard F. Mortensen.
5084 Metabolism of 7,8-Dihydrobenzo(a)pyrene by Rat Liver Micro-soma! Enzymes and Mutagenicity of Metabolites. Pei-Lu Chiùand Shen K. Yang.
5095 Disposition of Homocysteine in Rat Hepatocytes and in Nonrrans-formed and Malignant Mouse Embryo Fibroblasts following Exposure to Inhibitors of S-Adenosylhomocysteine Catabolism.Asbj0rn M. Svardal, Rune Djurhuus, Helga Refsum and PerMagne Ueland.
*5101 Coordinate Control of Anchorage Independence, Actin Cytoskel-
eton, and Angiogenesis by Human Chromosome 1 in Hamster-Human Hybrids. Noel Bouck, Andrea Stoler and Peter J.Polverini.
5106 Induction of Heat Shock Gene Expression without Heat Shockby Hepatocarcinogens and during Hepatic Regeneration in RatLiver. Brian I. Carr,Ting H. Huang, Carolyn H. Buzin and KeiichiItakura.
:¡:5I12 Biosynthesis and Expression of the Disialoganglioside GD2, a
Relevant Target Antigen on Small Cell LungCarcinomafor Monoclonal Antibody-mediated Cytolysis. David A. Cheresh, JayRosenberg, Kalpana Mujoo, Lynn Hirschowitz and Ralph A.Reisfeld.
5119 Isolation and Characterization of Complementary DNA Clonesfor Genes Overexpressed in Chemically Induced Rat Hepatomas.Marisol Corral, Nicole Defer, Brigitte Paris, Michel Raymondjean,Daniel Coreos, Lydie Tichonicky, Jacques Kruh, Denise Glaise,Bernard Kneip and Christiane Guguen-Guillouzo.
*5125 Characterization of a New Drug-resistant Human Myeloma CellLine That Expresses P-Glycoprotein. William S. Dalton, BrianG. M. Durie, David S. Alberts, James H. Gerlach and Anne E.Cress.
5131 Effects of Swainsonine and Polyinosinic:Polycytidylic Acid onMurine Tumor Cell Growth and Metastasis. James W. Dennis.
* 5137 New Monoclonal Antibodies against Colon Cancer-associated An
tigens. B. Drewinko, L. Y. Yang, J. Chan and J. M. Trujillo.
5144 Distribution of Developmental Markers in Rat Mammary TumorsInduced by Ar-Nitrosomethylurea. Renato Dulbecco, BarbaraArmstrong, W. Ross Allen and Marianne Bowman.
*5153 Purification and Biological Properties of Type ßTransformingGrowth Factor from Mouse Transformed Cells. J. A. Fernandez-Pol, D. J. Klos and G. A. Grant.
*5162 Expression of Growth-regulated Genes in Human Acute Leuke-mias. Sergio Ferrari, Franco Narni, Wendy Mars, LeszekKaczmarek, Donatella Venturelli, Borje Anderson and BrunoCalabretta.
5167 Evidence That Intravenously Derived Murine Pulmonary Melanoma MétastasesCan Originate from the Expansion of a SingleTumor Cell. Isaiah J. Fidler and James E. Talmadge.
5172 Evidence That the Process of Murine Melanoma Metastasis IsSequential and Selective and Contains Stochastic Elements. JanetE. Price, Sharon Lea Aukerman and Isaiah J. Fidler.
* 5179 A Cell Line from a Human Ovarian Carcinomawith Amplificationof the K-ru.vGene. Jorge Filmus, Jeffrey M. Trent, Rose Pullanoand Ronald N. Buick.
* 518.1 Cell Surface Antigens of Human Bladder Tumors: Definition ofTumor Subsets by Monoclonal Antibodies and Correlation withGrowth Characteristics. Yves Fradet, Carlos Cordon-Cardo,Willet F. Whitmore, Jr., Myron R. Melamed and Lloyd J. Old.
*5189 Reactivity of Monoclonal Antibody DF3 with a High MolecularWeight Antigen Expressed in Human Ovarian Carcinomas. EliotL. Friedman, Daniel F. Hayes and Donald W. Kufe.
*5195 Mouse Monoclonal Antibody (FKH1) Detecting Human Melanoma-associated Antigens. Toru Fukaya, Ken Hashimoto, HikaruEto and Amir Mehregan.
* 5201 Organ Specific Neoantigens Reactive in the Leukocyte AdherenceInhibitionAssay: Affinity Purification of Human Colon CarcinomaAntigen and Its Cross-Reactive Protein Using Monoclonal Antibodies. Eran Hadas, Aaron Fink, Evgenia Gembom, NurithHarpaz, Adi Shani, Zvi Bentwich and Zelig Eshhar.
* 5206 Distribution of a Squamous Cell Lung Carcinoma-associated Antigen, KA-32, in Human Tissues and Sera Defined by MonoclonalAntibody KM-32. Nobuo Hanai, Kenya Shitara and HajimeYoshida.
5211 Roles of Cytomegalovirus and Chlamydia trachomatis in theInduction of Cervical Neoplasia in the Mouse. Alfred D. Heggie,W. Budd Wentz, James W. Reagan and Donald D. Anthony.
Continued
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
5215 Inhibition of Experimental Metastasis by Castanospermine inMice: Blockage of Two Distinct Stages of Tumor Colonization byOligosaccharide Processing Inhibitors. Martin J. Humphries,Kazue Matsumoto, Sandra L. White and Kenneth Olden.
* 5223 Biosynthesis and Intracellular Processing of Four Human Melanoma Associated Antigens. R. R. S. Kantor, A. P. Albino, A. K.Ng and S. Ferrane.
* 5229 Folinic Acid Augmentation of the Effects of Fluoropyrimidines onMurine and Human Leukemic Cells. Kliandan Keyomarsi andRichard G. Moran.
5236 Uptake, Cytofluorescence, and Cytotoxicity of Oxazolopyridocar-bazoles (Amino Acid-Ellipticine Conjugates) in Murine SarcomaCells. Annette K. Larsen, Jacques Paoletti, Jean Belehradek, Jr.,and Claude Paoletti.
*5241 Suppression of Glioma Growth in Vitro and in Vivo by GliaMaturation Factor. Ramon Lim, Danny J. Hicklin, Timothy C.Ryken, Xue-Mei Han, Kang-Nian Liu, Joyce F. Miller and BruceA. Baggenstoss.
* 5248 AVV-Dimethylformamide-induced Synthesis of an Anti-Fibronec-tin Reactive Protein in Cultured Human Colon Carcinoma Cells.Michael E. Marks, Barry L. Ziober and Michael G. Brattain.
5259 A Monoclonal Antibody Specific for the Yc Subunit of Rat LiverGlutathione S-Transferase B. Kozo Matsumoto, AkiraMatsuhashi, David L. Gasser and Gerald Litwack.
5264 Anticarcinogenic and Hepatotoxic Interactions between RetinylAcetate and Butylated Hydroxytoluene in Rats. David L.McCormick, Cynthia M. May, Cathy F. Thomas and Carol J.Detrisac.
5270 Implications of Endogenous Tumor Cell Surface I,retins as Mediators of Cellular Interactions and Lung Colonization. LeonidMeromsky, Reuben Lotan and Avraham Raz.
5276 TumorChemosensitivity Conferredby Inserted Herpes ThymidineKinase Genes: Paradigm for a Prospective Cancer Control Strategy. Frederick L. Moolten.
•':52K2Recurrent Chromosome Changes at 3p21 in Epstein-Barr Virus-
transformed Cells Derived from Human Prolymphocytic Leukemia. Kazuma Ohyashiki, Junko H. Ohyashiki, Alan J.KJnniburgh, Tin Han and Avery A. Sandberg.
5287 Analysis of Peroxisome Proliferator-induced Preneoplastic andNeoplastic Lesions of Rat Liver for Placenta! Form of GlutathioneS-Transferase and •y-Glutamyltranspeptidase.M. Sambasiva Rao,Masae Tatematsu, V. Subbarao, Nobuyuki Ito and Janardan K.Reddy.
^5291 Induction of an Unusual Type of Shared Phosphorylation inHuman and Avian Cells by Tumor-promoting Phorbol Esters orTransformation. Junji Sagara, Kenneth M. Yamada and TakeoKakunaga.
*5297 Amplification and Rearrangement of DNA Sequences from theChromosomal Region 2p24 in Human Neuroblastomas. YosefShiloh, Bruce Korf, Nancy E. Kohl, Kazuo Sakai, Garrett M.Brodeur, Peter Harris, Naotoshi Kanda, Robert C. Seeger,Frederick Alt and Samuel A. Latt.
5302 Enhanced Expression of e-myc and Decreased Expression of c-fosProtooncogenes in Chemically and Radiation-transformed C3H/IOTI/2 O 8 Mouse Embryo Cell Lines. Taro Shuin, Paul C.Billings, Johan R. Lillehaug, Steven R. Patierno, Pradip Roy-Burman and Joseph R. Landolph.
5312 Differentiation, Dedifferentiation, and Transdifferentiation ofBALB/c 3T3 T Mesenchymal Stem Cells: Potential Significancein Metaplasia and Neoplasia. Rodney L. Sparks, Elizabeth I.Seibel-Ross, Marjorie L. Wier and Robert E. Scott.
*5320
*5330
5335
*5339
5344
5349
*5353
5360
5364
5368
5372
5380
5385
5392
5401
5406
5409
Continued
Oxygénationand Differentiation in Multicellular Spheroids ofHuman Colon Carcinoma. R. M. Sutherland, B. Sordat, J. Bamat,H. Gabbert, B. Bourrâtand W. Mueller-Klieser.
Expression of Transferrin Receptors in Human ErythroleukemicLines: Regulation in the Plateau and Exponential Phase ofGrowth. E. Pelosi Testa, U. Testa, P. Samoggia, G. Salvo, A.Camagna and C. Peschle.
Genetic Variation in the Proliferation of Murine Pulmonary TypeII Cells: Basal Rates and Alterations following Urethan Treatment. LarryG. Thaete, David G. Beer and Alvin M. Malkinson.
Quantitation and Characterization of -y-InterferonReceptors on
Human Tumor Cells. U. Ãœcer,H. Bartsch, P. Scheurich, D.Berkovic, C. Ertel and K. Pfizenmaier.
Immunospecific Eosinophil Infiltration of a Mouse MammaryCarcinoma. Jan Vaage, Karen G. Pépinand Tamora L. Au.
2-Cyanocinnamic Acid Sensitization of L929 Cells to Killing byHyperthermia. Hui Wang and Karl W. Lanks.
Acid Protease Secreted from Human Pancreatic Carcinoma CellLine HPC-YT into Serum-free, Chemically Defined Medium.Nozomi Yamaguchi and Keiichi Kawai.
CLINICAL AND EPIDEMIOLOGICALINVESTIGATIONS
Case-Control Study of Decaffeinated Coffee Consumption andPancreatic Cancer. Ernst L. Wynder, Gretchen S. Dieck andNancy E. L. Hall.
Phase I/II Trial of Human Recombinant ^-Interferon Serine inPatients with Renal Cell Carcinoma. John Rinehart, LouisMalspeis, Donn Young and James Neidhart.
Phase I Study of aj-Interferon plus Doxorubicin in Patients withSolid Tumors. GisèleA. Sarosy, Thomas D. Brown, Daniel D.Von Hoff, Robert J. Spiegel, James P. Colando, Kenneth L.Beougher, John G. Kühnand Daniel L. Kisner.
Predictive Model for Prognosis in Advanced Diffuse HistiocyticLymphoma. Linda Danieu, George Wong, Benjamin Koziner andBayard Clarkson.
Prediction of Clinical Outcome with Estrogen and Progestin Receptor Concentrations and Their Relationships to Clinical andHistopathological Variables in Endometrial Cancer. Antti J. I.Kauppila, Hannu E. Isolalo, Seppo T. Kivinen and Reijo K.Vihko.
Acute and Long-Term Effects of High-Dose Methotrexate Treatment on Homocysteine in Plasma and Urine. H. Refsum, P. M.Ueland and S. Kvinnsland.
Urinary Excretion of Nitrosodimethylamine and Nitrosoproline inHumans: Interindividualand Intraindividual Differences and theEffect of Administered Ascorbic Acid and a-Tocopherol. WilliamA. Garland, Wolfgang Kuenzig, Felix Rubio, Halyna Kornychuk,Edward P. Norkus and Allan H. Conney.
Activation or Suppression of the Tumoricidal Properties ofMonocytes from Cancer Patients following Treatment withHuman Recombinant-y-Interferon.Eugenie S. Kleinerman, RazelleKurzrock, Deborah Wyatt, Jorge R. Quesada,Jordan U. Gutterman and Isaiah J. Fidler.
Significance of 1,25-Dihydroxyvitamin I), Receptor in PrimaryBreast Cancers. John A. Eisman, Larry J. Suva and T. JohnMartin.
Methylthioadenosine Phosphorylase Deficiency in Human Leu-kemias and Solid Tumors. John H. Fitchen, Michael K. Risene,Bruce W. Dana, H. Jeffrey Lawrence and Adolph J. Ferro.
This One
OWX2-F42-HBLKon March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
r 5413 In Vitro Analysis of Donor Bone Marrow following MonoclonalAntibody Treatment for the Prevention of Acute Graft versusHostDisease. Peter C. Kohler, Christene Erickson, Johnathan L.Finlay, Michael E. Trigg, Bruce Edwards, Richard Hong,Jacquelyn A. Hank, Ronald Billing, Marek Bozdech and Paul M.Sondel.
5419 Immunohistochemical Analyses of Estrogen Receptor in Endo-metrial Adenocarcinoma Using a Monoclonal Antibody. Debra A.Budwit-Novotny, Kenneth S. McCarty, Edwin B. Cox, John T.Soper, David G. Mutch, William T. Creasman, Julie L. Flowersand Kenneth S. McCarty, Jr.
5426 Inhibition of Human Colonie Epithelial Cell Proliferation in Vivoand in Vitro by Calcium. Michel Buset, Martin Lipkin, SidneyWinawer, Shanti Swaroop and Eileen Friedman.
5431 Cellular Distribution of a B-Cell Specific Surface Antigen (gp54)Detected by a Monoclonal Antibody (Anti-BL4). Labib Hashimi,Chang Yi Wang, Ayad Al-Katib and Benjamin Koziner.
5438 Xenobiotic Metabolism in Human Alveolar Type II Cells Isolatedby Centrifugal Elutriation and Density Gradient Centrifugation.Theodora R. Devereux, Thomas E. Massey, Michael R. Van Scott,James Yankaskas and James R. Fouts.
5444 Elevated Levels of a High Molecular Weight Antigen Detectedby Antibody Wl in Sera from Breast Cancer Patients. Peter S.Linsley, Vincent Ochs, Sharon Laska, Diane Horn, David B.Ring, Arthur E. Frankel and Joseph P. Brown.
Letter to the Editor
5451 Free Radicals in Carcinogenesis. Edmund S. Copeland.
5452 Announcements
5453 ErrataV. L. Ernster, 46: 3202-3203, 1986.R. R. Salup and R. H. Wiltrout, 46: 3358-3363, 1986.L. Gross et al., 46:2984-2987, 1986.E. Katz and B. J. Carter, 46: 3023-3026, 1986.
5454 Author Index
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
Cancer Research
VOLUME 46 •NUMBER 10
CONTENTS Arranged by Subject Category
Perspectives in Cancer Research
4879 O-Alkyl Pyrimidines in Mutagenesis and Carcinogenesis: Occurrence and Significance. B. Singer.
BASIC SCIENCES
Biochemistry and Biophysics5020 Interaction of Polyglutamyl Derivatives of Methotrexate, 10-De-
azaaminopterin, and Dihydrofolate with Dihydrofolate ReducÃase.Piyush Kumar, Roy L. Kisliuk, Yvette Gaumont, Madhavan G.Nair, Charles M. Baugh and Bernard T. Kaufman.
*5153 Purification and Biological Properties of Type ßTransformingGrowth Factor from Mouse Transformed Cells. J. A. Fernandez-
Pol, D. J. Klos and G. A. Grant.
5287 Analysis of Peroxisome Proliferator-induced Preneoplastic andNeoplastic Lesions of Rat Liver for Placenta! Form of GlutathioneS-Transferase and -y-Glutamyltranspeptidase. M. Sambasiva Rao,
Masae Tatematsu, V. Subbarao, Nobuyuki Ito and Janardan K.Reddy.
*5291 Induction of an Unusual Type of Shared Phosphorylation inHuman and Avian Cells by Tumor-promoting Phorbol Esters orTransformation. Junji Sagara, Kenneth M. Yamada and TakeoKakunaga.
* 532(1 Oxygénationand Differentiation in Multicellular Spheroids ofHuman Colon Carcinoma. R. M. Sutherland, B. Sordat, J. Bamat,H. Gabbert, B. Bourrâtand W. Mueller-Klieser.
* 5339 Quantitation and Characterization of -y-InterferonReceptors on
Human Tumor Cells. U. Ãœcer,H. Bartsch, P. Scheunen, D.Berkovic, C. Ertel and K. Pfizenmaier.
*5353 Acid Protease Secreted from Human Pancreatic Carcinoma CellLine HPC-YT into Serum-free, Chemically Defined Medium.Nozomi Yamaguchi and Keiichi Kawai.
Biology
4966 Treatment of Experimental Lung Metastasis with Local ThoracicIrradiation Followed by Systemic Macrophage Activation withLiposomes Containing Murarmi Tripeptide. Ikuo Saiki, LukaMilas, Nancy Hunter and Isaiah J. Fidler.
* 5101 Coordinate Control of Anchorage Independence, Actin Cytoskel-eton, and Angiogenesis by Human Chromosome 1 in Hamster-Human Hybrids. Noel Bouck, Andrea Stoler and Peter J.Polverini.
5167 Evidence That Intravenously Derived Murine Pulmonary Melanoma MétastasesCan Originate from the Expansion of a SingleTumor Cell. Isaiah J. Fidler and James E. Talmadge.
5172 Evidence That the Process of Murine Melanoma Metastasis IsSequential and Selective and Contains Stochastic Elements. JanetE. Price, Sharon Lea Aukerman and Isaiah J. Fidler.
*5248 /V./V-Dimi'thylformamidc-inducedSynthesis of an Anti-Fibronec-tin Reactive Protein in Cultured Human Colon Carcinoma Cells.Michael E. Marks, Barry L. Ziober and Michael G. Brattain.
5270 Implications of Endogenous Tumor Cell Surface Lectins as Mediators of Cellular Interactions and Lung Colonization. LeonidMeromsky, Reuben Lotan and Avraham Raz.
* Indicates studies using human-derived material.
*52H2 Recurrent Chromosome Changes at 3p21 in Epstein-Barr Virus-transformed Cells Derived from Human Prolymphocytic Leukemia. Ka/uma Ohyashiki, Junko H. Ohyashiki, Alan J.Kinniburgh, Tin Han and Avery A. Sandberg.
*5297 Amplification and Rearrangement of DNA Sequences from theChromosomal Region 2p24 in Human Neuroblastomas. YosefShiloh, Bruce Korf, Nancy E. Kohl, Kazuo Sakai, Garrett M.Brodeur, Peter Harris, Naotoshi Kanda, Robert C. Seeger,Frederick Alt and Samuel A. Latt.
5312 Differentiation, Differentiation, and Transdifferentiation ofBALB/c 3T3 T Mesenchymal Stem Cells: Potential Significancein Metaplasia and Neoplasia. Rodney L. Sparks, Elizabeth I.Seibel-Ross, Marjorie L. Wier and Robert E. Scott.
* 5330 Expression of Transfer™Receptors in Human ErythroleukemicLines: Regulation in the Plateau and Exponential Phase ofGrowth. E. Pelosi Testa, U. Testa, P. Samoggia, G. Salvo, A.Camagna and C. Pésenle.
5335 Genetic Variation in the Proliferation of Murine Pulmonary TypeII Cells: Basal Rates and Alterations following Urethan Treatment. Larry G. Thaete, David G. Beer and Alvin M. Malkinson.
Carcinogenesis
4911 Tumorigenesis and Genotoxicity of Ethyl Car buinato and VinylCarbamate in Rodent Cells. James W. Allen, Gary D. Stoner,Michael A. Pereira, Lorraine C. Backer, Yousuf Sharief, GeorgeG. Hatch, James A. Campbell, Andrew G. Stead and StephenNesnow.
* 4942 Interspecies Comparison of Human and Rat Mammary EpithelialCell-mediated Mutagenesis by Polycyclic Aromatic Hydrocarbons. Michael N. Gould, Dorene R. Grau, Lisa A. Seidman andCynthia J. Moore.
*4946 Interspecies Comparison of Polycyclic Aromatic HydrocarbonMetabolism in Human and Rat Mammary Epithelial Cells.Cynthia J. Moore, William A. Tricomi and Michael N. Gould.
5068 Activation of the Colon Carcinogen 1,2-Dimethylhydrazine in aRat Colon Cell-mediated Mutagenesis Assay. Carol T. Oravec,Carol A. Jones and Eliezer Huberman.
5072 Effects of Neonatal and Adult Castration on the in Vitro Metabolism of Steroids and Xenobiotics in Rat Liver. Agneta Blanck,Anders Aströmand Tiiu Hansson.
5084 Metabolism of 7,8-Dihydrobenzo(a)pyrene by Rat Liver Micro-soma! Enzymes and Mutageniciry of Metabolites. Pei-Lu Chiùand Shen K. Yang.
5106 Induction of Heat Shock Gene Expression without Heat Shockby Hepatocarcinogens and during Hepatic Regeneration in RatLiver. Brian I. Carr, Ting H. Huang, Carolyn H. Buzin and KeiichiItakura.
5144 Distribution of Developmental Markers in Rat Mammary TumorsInduced by iV-Nitrosomethylurea. Renato Dulbecco, BarbaraArmstrong, W. Ross Allen and Marianne Bowman.
5211 Roles of Cytomegalovirus and CHlamydia trachomatis in theInduction of Cervical Neoplasia in the Mouse. Alfred D. I leggio,W. Budd Wentz, James W. Reagan and Donald D. Anthony.
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
5264 Anticarcinogenic and Hepatotoxic Interactions between RetinylAcetate and Butylated Hydroxytoluene in Rats. David L.McCormick, Cynthia M. May, Cathy F. Thomas and Carol J.Detrisac.
5302 Enhanced Expression of c-myc and Decreased Expression of c-fosProtooncogenes in Chemically and Radiation-transformed C'311/
IOTI/2 CI 8 Mouse Embryo Cell Lines. Taro Shuin, Paul C.Billings, Johan R. Lillehaug, Steven R. Patierno, Pradip Roy-Burman and Joseph R. Landolph.
Endocrinology:'"4927 Effects of Glucocorticoids on the Growth of Human Fibrosarcoma
Cell Line HT-1080. Michael J. Walker, Custodio Lim, Tapas K.Das Gupta and Craig W. Beattie.
*4<J33 Stimulation of Cell Proliferation and Estrogenic Response byAdrenal C,,-A*-Steroids in the ZR-75-1 Human Breast Cancer
Cell Line. Richard Poulin and Fernand Labrie.
4938 Polyamines and Hormonal Regulation of yV-Nitrosomethylurea-induced Rat Mammary Tumor Growth in Vivo. Andrea Manni,Carol Wright, Lawrence Demers and Gordon Luk.
:i'4979 Effects of Calcitriol on Nuclear Transcription during Human III-
60 Promyelocytic Leukemia Cell Differentiation. Emery H.Bresnick and Robert U. Simpson.
Immunology
4921 Comparison of the Tumor-associated Transplantation Antigens ofSublines of Methylcholanthrene-induced Murine Tumors Passaged Separately in Vivo for over a Decade. David L. Hiñes.
4953 Modulation of B16 Melanoma Antigen Expression by Lympho-kines and Dimethyl Sulfoxide. Kevin L. Trimpe and Bruce S.Zwilling.
4971 Paradoxical Effect of Three-Day Thymectomy on Sarcogenesis inthe Mouse with Different Dosages of Methylcholanthrene. LiisaM. Prehn and Akinori Kojima.
4973 Antitumor Efficacy of Lymphokine-activated Killer Cells andRecombinant Interleukin 2 in Vivo:Successful ImmunotherapyofEstablished Pulmonary Métastasesfrom Weakly Immunogenicand Nonimmunogenic Murine Tumors of Three Distinct Histológica! Types. Moshe Z. Papa, James J. Muléand Steven A.Rosenberg.
* 4984 Differential Effects of RecombinantHuman Leukocyte Interferonson Cell Surface Antigen Expression. John W. Greiner, Paul B.Fisher, Sidney Pestka and Jeffrey Schlom.
4991 In Vivo Generation of Tumor-specific Cytotoxic T-Cells in theRegional Lymph Node: Effect of Subcutaneous Inoculationof mis-disparate Spleen Cells aroundImplantedTumors in Mice. MinoraHigasa, Kazuhiko Yamada, Yutaka Takagaki, Masahiro Aoki,Sohei Shinka and Yoshitane Dohi.
5004 Inductionof Tumor Immunityand Natural Killer Cell Cytotoxicityin Mice by 5-HaIo-6-phenyl Pyrimidinone. Eva Lotzová,C. A.Savary, S. Pollack and N. Hanna.
* 5024 Demonstration of Epstein-Barr Virus-specific DNA Polymerasein Chemically Induced Raji Cells and Its Antibody in Serum fromPatients with Nasopharyngeal Carcinoma. Run-sheng Tan, Jin-sen Li, Susan P. Grill, Louise M. Nutter and Yung-chi Cheng.
* 5039 Lack of Production of Interleukin 1 by Human Blood MonocytesActivated to the Antitumor State by Liposome-encapsulated Mur-amyl Tripeptide. Priti Tandon, Teruhiro Utsugi and Saburo Soné.
5045 Detection of a Polyoma Virus-induced Tumor-associated Membrane Antigen in Mouse Cells by the Macrophage MigrationInhibition Test. Torbjörn Ramqvist, Tina Dalianis, GitReinholdsson, George Klein and Robert Szigeti.
5049 Complete Regression of Mouse Hepatoma Transplanted afterPartial Hepatectomy and the Immunological Mechanism of SuchRegression. Minoru Ono, Noriaki Tanaka and Kunzo Orita.
* 5077 Macrophage Tumoricidal Activity Induced by Human C-Reactive
Protein. Kamyar Zahedi and Richard F. Mortensen.•":5I12Biosynthesis and Expression of the Disialoganglioside GD2, a
Relevant Target Antigen on Small Cell LungCarcinomafor Monoclonal Antibody-mediated Cytolysis. David A. Cheresh, JayRosenberg, Kalpana Mujoo, Lynn Hirschowitz and Ralph A.Reisfeld.
* 5137 New Monoclonal Antibodies against Colon Cancer-associated An
tigens. B. Drewinko, L. Y. Yang, J. Chan and J. M. Trujillo.
*5I83 Cell Surface Antigens of Human Bladder Tumors: Definition ofTumor Subsets by Monoclonal Antibodies and Correlation withGrowth Characteristics. Yves Fradet, Carlos Cordon-Cardo,Willet F. Whitmore, Jr., Myron R. Melamed and Lloyd J. Old.
* 5189 Reactivity of Monoclonal Antibody DF3 with a High MolecularWeight Antigen Expressed in Human Ovarian Carcinomas. EliotL. Friedman, Daniel F. Hayes and Donald W. Kufe.
*5195 Mouse Monoclonal Antibody (1 Kill) Detecting Human Melanoma-associated Antigens. Toni Fukaya, Ken Hashimoto, HikaruEto and Amir Mehregan.
'f 5201 Organ Specific Neoantigens Reactive in the Leukocyte Adherence
Inhibition Assay: Affinity Purificationof Human Colon CarcinomaAntigen and Its Cross-Reactive Protein Using Monoclonal Antibodies. Eran Hadas, Aaron Fink, Evgenia Gembom, NurithHarpaz, Adi Shani, Zvi Bentwich and Zelig Eshhar.
* 5206 Distribution of a Squamous Cell Lung Carcinoma-associated Antigen, KA-32, in Human Tissues and Sera Defined by MonoclonalAntibody KM-32. Nobuo Hanai, Kenya Shitara and HajimeYoshida.
* 5223 Biosynthesis and Intracellular Processing of Four Human Mela
noma Associated Antigens. R. R. S. Kantor, A. P. Albino, A. K.Ng and S. Ferrone.
5259 A Monoclonal Antibody Specific for the Yc Subunit of Rat LiverGlutathione 5-Transferase B. Kozo Matsumoto, AkiraMatsuhashi, David L. Gasser and Gerald Litwack.
5344 Immunospecific Eosinophil Infiltration of a Mouse MammaryCarcinoma. Jan Vaage, Karen G. Pépinand Tamora L. Au
Molecular Biology and Genetics
5119 Isolation and Characterization of Complementary DNA Clonesfor Genes Overexpressed in Chemically Induced Rat Hepatomas.Marisol Corral, Nicole Defer, Brigitte Paris, Michel Raymondjean,Daniel Coreos, Lydie Tichonicky, Jacques Kruh, Denise Glaise,Bernard Kneip and Christiane Guguen-Guillouzo.
•'•5162 Expression of Growth-regulated Genes in Human Acute Leuke-
mias. Sergio Ferrari, Franco Narni, Wendy Mars, LeszekKaczmarek, Donatella Venturelli, Borje Anderson and BrunoCalabretta.
* 5179 A Cell Line from a Human OvarianCarcinomawith Amplificationof the K-ras Gene. Jorge Filmus, Jeffrey M. Trent, Rose Pullanoand Ronald N. Buick.
Preclinical Pharmacology and Experimental Therapeutics*4886 Preclinical Trials with Combinations and Conjugates of T101
Monoclonal Antibody and Doxorubicin. Robert O. Dillman,Daniel L. Shawler, Duane E. Johnson, Damon L. Meyer, JamesA. Koziol and James M. Frincke.
*4892 Comparison of the Cytotoxic Effects of Merocyanine-540 on Leu-kemic Cells and Normal Human Bone Marrow. Jens Atzpodien,Subhash C. Gulati and Bayard D. Clarkson.
Continued
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
*48% Hypoxanthine:Guanine Phosphoribosyltransferase Activity inXenografts of Human Osteosarcoma. William H. Meyer, Janet A.Houghton, Pamela J. Lutz and Peter J. Houghton.
*4900 Identification of Metabolites of the Cell-differentiating AgentHexamethylene Bisacetamide in Humans. Patrick S. Gallery,Merrill J. Egorin, Linda A. Geelhaar and M. S. BalachandranNayar.
* 4904 Antibody-directed Liposomes: Comparison of Various Ligands forAssociation, Endocytosis, and Drug Delivery. Katherine K.Matthay, Timothy D. Heath, Christopher C. Badger, Irwin D.Bernstein and Demetrios Papahadjopoulos.
*4916 Augmentation of Cytotoxicity of Chemotherapy by Human a-Interferons in Human Non-Small Cell Lung Cancer Xenografts.James Carmichael, Ronald J. Fergusson, C. Roland Wolf, FrancesR. Balkwill and John F. Smyth.
4960 Correlation of Biochemical Effects and Incorporation of 3-De-azaguanine into Nucleic Acids to Cytotoxicity in LI 210 Cells.Russell O. Pieper, Louis R. Barrows and H. George Mandel.
*4995 Combined Effects of Streptozotocin and Mitozolomide againstFour Human Cell Lines of the Mer* Phenotype. Neil W. Gibson,
John A. Hartley, Diane Barnes and Leonard C. Erickson.
* 4999 Differential Cytotoxicity and DNA-damaging Effects Produced inHuman Cells of the Mer* and Mer~ Phenotypes by a Series of 1-
Aryl-3-alkyltriazenes. Neil W. Gibson, John A. Hartley, RonaldJ. LaFrance and Keith Vaughan.
*5009 Cross-Sensitivity of Methylating Agents, Hydroxyurea, andMethotrexate in Human Tumor Cells of the Mer~ Phenotype.
Kevin Maynard and Peter G. Parsons.
* 5(114 Mechanism of Action of the Novel Anticancer Agent 6-Fluoro-2-(2'-fluoro-l,l'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic
Acid Sodium Salt (NSC 368390): Inhibitionof de Novo PyrimidineNucleotide Biosynthesis. Shih-Fong Chen, Regina L. Ruben andDaniel L. Dexter.
* 5029 Cytotoxicity, DNA Cross-Linking, and Single Strand Breaks Induced by Activated Cyclophosphamide and Acrolein in HumanLeukemia Cells. Tim R. Crook, Robert L. Souhami and AndréE. M. McLean.
* 5035 Glutathione Depletion as a Determinant of Sensitivity of HumanLeukemia Cells to Cyclophosphamide. Tim R. Crook, Robert L.Souhami, Gillian D. Whyman and A. E. M. McLean.
* 5(15-4 Modulation of the Antitumor and Biochemical Properties ofBis(diphenylphosphine)ethane with Metals. Rosanne M. Snyder,Christopher K. Mirabelli, Randall K. Johnson, Chiù-Mei Sung,Leo F. Faucette, Francis L. McCabe, Joseph P. Zimmerman,Matthew Whitman, Judith C. Hempel and Stanley T. Crooke.
*5061 Effects of Thromboxane A2 Inhibition on Osteogenic SarcomaCell-induced Platelet Aggregation. Paulette Mehta, DanielLawson, Mary Beth Ward, Linda Lee-Ambrose and ArthurKimura.
5064 Dansyl Lysine, a New Probe for Assaying Heat-induced CellKilling and Thermotolerance in Vitro and in Vivo. George Fisher,Glenn C. Rice and George M. Hahn.
5095 Disposition of Homocysteine in Rat Hepatocytes and in Nontrans-formed and Malignant Mouse Embryo Fibroblasts following Exposure to Inhibitors of S-Adenosylhomocysteine Catabolism.Asbj0rn M. Svardal, Rune Djurhuus, Helga Refsum and PerMagne Ueland.
:';5I25 Characterization of a New Drug-resistant Human Myeloma CellLine That Expresses /'-Glycoprotein. William S. Dalton, BrianG. M. Dune, David S. Alberts, James H. Gerlach and Anne E.Cress.
5131
5215
*5229
5236
*5241
5276
5349
5364
5368
5372
5380
5385
5392
5401
5406
5409
Effects of Swainsonine and Polyinosinic:Polycytidylic Acid onMurine Tumor Cell Growth and Metastasis. James W. Dennis.
Inhibition of Experimental Metastasis by Castanospermine inMice: Blockage of Two Distinct Stages of Tumor Colonization byOligosaccharide Processing Inhibitors. Martin J. Humphries,Kazue Matsumoto, Sandra L. White and Kenneth Olden.
Folinic Acid Augmentation of the Effects of FluoropyrimidinesonMurine and Human Leukemic Cells. Khandan Keyomarsi andRichard G. Moran.
Uptake, Cytofluorescence, and Cytotoxicity of Oxazolopyridocar-bazoles (Amino Acid-Ellipticine Conjugates) in Murine SarcomaCells. Annette K. Larsen, Jacques Paoletti, Jean Belehradek, Jr.and Claude Paoletti.
Suppression of Glioma Growth in Vitro and in Vivo by GliaMaturation Factor. Ramon Lim, Danny J. Hicklin, Timothy C.Ryken, Xue-Mei Han, Kang-Nian Liu, Joyce F. Miller and BruceA. Baggenstoss.
TumorChemosensitivity Conferredby Inserted Herpes ThymidineKinase Genes: Paradigm for a Prospective Cancer Control Strategy. Frederick L. Moolten.
2-Cyanocinnamic Acid Sensitizaron of L929 Cells to Killing byHyperthermia. Hui Wang and Karl W. Lanks.
CLINICAL AND EPIDEMIOLOGICALINVESTIGATIONS
Clinical
Phase I/II Trial of Human Recombinant 0-Interferon Serine inPatients with Renal Cell Carcinoma. John Rinehart, LouisMalspeis, Donn Young and James Neidhart.
Phase I Study of a2-Interferon plus Doxorubicin in Patients withSolid Tumors. GisèleA. Sarosy, Thomas D. Brown, Daniel D.Von Hoff, Robert J. Spiegel, James P. Colando, Kenneth L.Beougher, John G. Kühnand Daniel L. Kisner.
Predictive Model for Prognosis in Advanced Diffuse HistiocyticLymphoma. Linda Danieu, George Wong, Benjamin KozinerandBayard Clarkson.
Prediction of Clinical Outcome with Estrogen and Progestin Receptor Concentrations and Their Relationships to Clinical andHistopathological Variables in Endometrial Cancer. Antti J. I.Kauppila, Hannu E. Isolalo, Seppo T. Kivinen and Reijo K.Vihko.
Acute and Long-Term Effects of High-Dose Methotrexate Treatment on Homocysteine in Plasma and Urine. H. Refsum, P. M.Ueland and S. Kvinnsland.
Urinary Excretion of Nitrosodimethylamine and Nitrosoproline inHumans: Interindividualand Intraindividual Differences and theEffect of Administered Ascorbic Acid and or-Tocopherol.WilliamA. Garland, Wolfgang Kuenzig, Felix Rubio, Halyna Kornychuk,Edward P. Norkus and Allan H. Conney.
Activation or Suppression of the Tumoricidal Properties ofMonocytes from Cancer Patients following Treatment withHuman Recombinant •y-Interferon.Eugenie S. Kleinerman,Razelle Kurzrock, Deborah Wyatt, Jorge R. Quesada,Jordan U. Gutterman and Isaiah J. Fidler.
Significance of 1,25-Dihydroxyvitamin I), Receptor in PrimaryBreast Cancers. John A. Eisman, Larry J. Suva and T. JohnMartin.
Methylthioadenosine Phosphorylase Deficiency in Human Leu-kemias and Solid Tumors. John H. Fitchen, Michael K. Risc-oc.
Bruce W. Dana, H. Jeffrey Lawrence and Adolph J. Ferro.
Continued
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
5413 In Vitro Analysis of Donor Bone Marrow following MonoclonalAntibody Treatment for the Prevention of Acute Graft versusHostDisease. Peter C. Kohler, Christene Erickson, Johnathan L.Finlay, Michael E. Trigg, Bruce Edwards, Richard Hong,Jacquelyn A. Hank, Ronald Billing, Marek Bozdech and Paul M.Sondel.
5419 Immunohistochemical Analyses of Estrogen Receptor in Endo-metrial Adenocarcinoma Using a Monoclonal Antibody. Debra A.Budwit-Novotny, Kenneth S. McCarty, Edwin B. Cox, John T.Soper, David G. Mutch, William T. Creasman, Julie L. Flowersand Kenneth S. McCarty, Jr.
5426 Inhibition of Human Colonie Epithelial Cell Proliferation in Vivoand in Vitro by Calcium. Michel Buset, Martin Lipkin, SidneyWinawer, Shanti Swaroop and Eileen Friedman.
5431 Cellular Distribution of a B-Cell Specific Surface Antigen (gp54)Detected by a Monoclonal Antibody (Anti-BL4). Labib Hashimi,Chang Yi Wang, Ayad Al-Katib and Benjamin Koziner.
5438 Xenobiotic Metabolism in Human Alveolar Type II Cells Isolatedby Centrifugal Elutriation and Density Gradient Centrifugation.Theodora R. Devereux, Thomas E. Massey, Michael R. Van Scott,James Yankaskas and James R. Fouts.
5444 Elevated Levels of a High Molecular Weight Antigen Detectedby Antibody Wl in Sera from Breast Cancer Patients. Peter S.Linsley, Vincent Ochs, Sharon Laska, Diane Horn, David B.Ring, Arthur E. Frankel and Joseph P. Brown.
Epidemiológica!5360 Case-Control Study of Decaffeinated Coffee Consumption and
Pancreatic Cancer. Ernst L. Wynder, Gretchen S. Dieck andNancy E. L. Hall.
Letter to the Editor
5451 Free Radicals in Carcinogenesis. Edmund S. Copeland.
5452 Announcements
5453 ErrataV. L. Ernster, 46: 3202-3203, 1986.R. R. Salup and R. H. Wiltrout, 46: 3358-3363, 1986.L. Gross et al, 46: 2984-2987, 1986.E. Katz and B. J. Carter, 46: 3023-3026, 1986.
5454 Author Index
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from
1986;46:4879-5453. Cancer Res 46 (10)
Updated version
http://cancerres.aacrjournals.org/content/46/10.citation
Access the most recent version of this article at:
E-mail alerts related to this article or journal.Sign up to receive free email-alerts
Subscriptions
Reprints and
To order reprints of this article or to subscribe to the journal, contact the AACR Publications
Permissions
Rightslink site. Click on "Request Permissions" which will take you to the Copyright Clearance Center's (CCC)
.http://cancerres.aacrjournals.org/content/46/10.citationTo request permission to re-use all or part of this article, use this link
on March 24, 2020. © 1986 American Association for Cancer Research.cancerres.aacrjournals.org Downloaded from