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Greetings and best wishes for the new academic year!

I am pleased to welcome our new faculty member, Joshua Osbun, M.D., to the department. Dr. Osbun attended Texas A&M University prior to obtaining his M.D. degree at The University of Texas Southwestern. He subsequently completed his residency training in neurological surgery at The University of Washington, which was followed by a fellowship at Emory University in cerebrovascular surgery and interventional neuroradiology. I am very excited that we have recruited Dr. Osbun to Washington University and believe he will be a wonderful addition to our faculty.

I also want to extend a warm welcome to our new fellows and in-terns. You follow in the footsteps of giants, including Dr. Albert L. Rhoton, Jr., Dr. Sidney Goldring, Dr. Henry Schwartz, and others. We have high expectations of all of you and have confidence that you will achieve and surpass them.

Ralph G. Dacey Jr., M.D. Henry G. & Edith R. Schwartz Professor and Chairman of Neurological Surgery

Message from the Chairman

I N S I D E T H I S

I S S U E :

A Neurosurgeon’s Nightmare

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Patient Voices 3

Honors and Awards

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New Residents, Fellows, and Faculty

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New South County Location

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Neuro-Oncology Consortium

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Student Lab Day 7

Grants 8

Publications 9-12

Presentations 13-15

New Staff 15

Personal News 16

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Neurosurgery Frontiers J U L Y 2 0 1 6 V O L U M E 6 , I S S U E 2

David Limbrick Named Division Chief of Pediatric Neurosurgery David D. Limbrick Jr., M.D., Ph.D., assumed the role of Chief of Pediatric Neurosurgery at Washington University School of Medicine in St. Louis and Neurosurgeon-in-Chief at St. Louis Children’s Hospital in May 2016.

Dr. Limbrick completed his neurosurgery residency and pediatric neurosurgery fellowship at Washington University. After completing his fellowship in 2008, he joined the department as an assistant professor. He has been very active in the department, serving as associate director of the neurosurgery residency program, the co-director of the pediatric neurosurgery fellowship and co-director of the pediatric neuro-oncology program at Washington University School of Medicine.

Most recently Dr. Limbrick was awarded a multi-year Patient-Centered Outcomes Research Institute (PCORI) grant for a 47-center randomized controlled trial comparing the two most common neurosurgical treatments for Chiari type I malformation with syringomyelia. Dr. Limbrick is also the principal investigator and associate director of the Park/Reeves Center for Syringomyelia Research and is the Washington University principal investigator for the Hydrocephalus Clinical Research Network (HCRN).

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I never dreamed that I would be forced to stop operating during my career as a neurosurgeon, especially at 49 years of age; however, it happened.

I started my freshman year at the University of Oklahoma as a pre-med student and graduated with a Bachelor of Science in Zoology and a Bachelor of Arts in Philosophy. Luckily, by adding a second major, I spent another year in college, and the summer before my super-senior year, I met my future wife. Ironically, and in retrospect, I also remember that’s when my tremors began. At that time, I only seemed to have it while nervous, so I didn’t think much about it.

After graduation, I started medical school at the University of Oklahoma. I remember when I tried to draw blood from one of my classmates for the first time, it was an epic fail due to my hands shaking. Again, it only occurred if I was nervous or anxious. Once I became comfortable in the operating room and doing various other procedures (central lines, suturing), I had no issues with the tremors. During the spring of my third year, I was allowed to take my surgical elective, and I chose neurosurgery, mostly because I had done general surgery and I was not interested in orthopaedics. I knew nothing about neurosurgery and had never seen a craniotomy or a spine operation. I was assigned to a group of three private practice neurosurgeons and reported to the operating room where the surgeon was getting ready to start a craniotomy for a resection of a large convexity meningioma. I assisted him as directed, and I watched him turn the bone flap (which was cool), then open the dura, which was way cool. I then watched him resect the tumor, and all I could think was this poor patient is going to be maimed if they even survive. After the resection, we closed, and I continued to think about was how doomed this patient was. Shortly after taking the patient out of the head holder, the anesthesiologist extubated her and she immediately began talking — I was hooked. Blurry Internship and Residency Years I spent the rest of the month with that group and loved all aspects of neurosurgery. At the advice of one of my professors, I went to Washington University in St. Louis for a month-long rotation at the beginning of my fourth year. That rotation was the best experience I had in medical school. At the recommendation of Ralph G. Dacey, Jr., M.D., F.A.A.N.S., I applied to about 25 residency programs. I was granted about 19 interviews, but stopped after 12 because I knew what I wanted. I

remember it like it was yesterday — the day I was paged by medical school administration to tell me that I had matched and would be going to Washington University for my residency. The first three years of residency are somewhat fuzzy in my memory. I do not recall my tremors being an issue; however, one of my attendings noticed it. Every year, we (the residents) would have a one-on-one meeting with Dr. Dacey to review board scores and discuss our future. I was just starting in the research lab and feeling good about things, when Dr. Dacey asked me to see a movement disorder specialist about my tremors. This was the first time anyone had ever mentioned this, and I was scared. Essential Tremor Diagnosis I blew off seeing Dr. Perlmutter, the specialist, for about six months because I was in denial. However, in the research lab, I was trying to develop a novel functional tumor model by injecting glioma cells into the whisker barrel cortex of rats and mice, and these surgeries were becoming more and more difficult to do. After I saw Dr. Permutter, however, it was official — I had essential tremor. I was bummed until I started taking the Primidone that he prescribed, and it helped significantly. I then finished my research, my wife and I had our first child, I was getting ready to be chief resident and I had signed a contract to join the group of neurosurgeons that I worked with as a student. All was going well. The Primidone continued to work well. I can only recall one time during my chief year that it was a problem. I was clipping an aneurysm with Dr. Dacey, and as I started to deploy the clip, I could feel the clip applicator start to slip in my hand. I froze, knowing my hands were going to start shaking. I feared that if I deployed the clip, I would have avulsed the aneurysm off the parent vessel and probably would have killed the patient. Fortunately, I was able to remove the clip and then watched as Dr. Dacey smoothly and precisely clipped the aneurysm. I knew he could see my hands shaking, but he never said a word to me about it. Working with Essential Tremor In July 2000, my family and I moved to Tulsa, Okla., so I could begin my practice. At that time, I was the seventh neurosurgeon in my group, and I got busy very quickly. The Primidone was working well, and I was not having any issues. However, I applied for

A Neurosurgeon’s Nightmare: Essential Tremor

By Eric W. Sherburn, M.D. Excerpted from AANS Neurosurgeon: Volume 25, Number 1, 2016

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disability insurance and was denied. I was told I had to be in practice for two years before they would insure me due to my tremors. That triggered our group to take out a group disability policy so I could have some coverage. At the time, I was more concerned about a car wreck or skiing accident than I was my tremor. After two years in practice, I reapplied for disability, was still taking Primidone, and the insurance company grant-ed my policy. I continued to do well; in fact, I stopped taking the Primidone for a few years as my tremor didn’t bother me. However, that would later change. In 2002, I was back on medication, and at one point was on Pro-pranolol, Primidone and Topamax at increasing doses. I could not tolerate the Topamax and stopped it. I continued on the Propranolol and Primidone for some time, but eventually stopped the Primidone, as I could-n’t tell if it was helping at all. My tremor was becoming noticeable in public as well. I developed changes in my behavior, as well as surgical techniques, to adapt to my situation. It had gotten to the point that what used to be my most enjoyable days (OR days) were now my most dreaded. I was scared to death that I was going to have a CSF leak because I knew if I did, I could not fix it. The Decision to Stop Operating For the last 15 years, my OR days were on Mondays and Wednesdays and clinic days were on Tuesdays and Thursdays. Late last January, I went to my office for a Tuesday clinic and found that I only had four patients to see. I thought it was slow because patients had not met deductibles, etc. Then, when I came in on Thursday, I only had three patients to see. I asked my nurse to look at my partner’s schedules to see if they were slow — and they were not. I asked her why she thought it was so slow, and she said she thought it was due to my tremor and informed me that more and more patients were asking her about it, even referring physicians were asking about it. I knew instantly that I needed to stop operating.

I got home early that day and told my wife my decision. Without hesitating, she expressed her full support and understanding, and at that moment, I felt an immediate burden being lifted. Restructuring a New Career I then began the task of rebuilding a meaningful career, as well as applying for disability benefits. I had been the concussion doctor at my kids’ school for four years and was interested in this, especially now, because concussions are non-operative. This past year, I have become a concussion specialist for a Division I university, as well as an unaffiliated neurotrauma consultant for the NFL, in large part thanks to the friends I have made along this journey. I will also be joining the faculty at the University of Oklahoma School of Community Medicine to help develop a comprehensive concussion center. What I miss the most about operating is not so much the actual surgery (although I certainly do miss that), but the surgery “family.” I miss the interaction with colleagues and staff that I had for 15 years. Also, being trained as a surgeon, and not being able to operate anymore, I feel somewhat marginalized at times. However, there are other ways to be involved. For me, one of the most grati-fying ways is through various surgical organizations. The decrease in income has also been an issue for me, and more importantly, for my family. I worry about paying for my kids’ education, and I feel guilty my wife now has to plan our vacations based on how expensive they might be. On the other hand, I do get to spend more time with my family, which means a great deal to me. Although I no longer have the stress of being an active surgeon anymore, it has been replaced with others, such as financial stress and remaining relevant to my community, as well as the neurosurgical community. In conclusion, the best advice I have to offer is to find good disability insurance, and get as much as you can, because you never know.

A Neurosurgeon’s Nightmare cont.

Patient Voices Comments directly from our patients about the care they received from the Neurosurgery healthcare team at Washington University

My doctors and nurses were all outstanding. My neurosurgeons took wonderful care of me no matter what time of day or night.

My entire stay was excellent. My doctor was always there, the therapists were so patient. They all made me happy while I was there.

I was happy with my entire experience. Everybody was so positive, upbeat, and they dealt with my nonsense well.

Everything about my stay was outstanding. Patients are well taken care of, and the doctors and nurses are great. It was just an excellent experience.

My level of care was outstanding. My doctors took the time to answer all of my questions and explain what was going on.

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Ralph G. Dacey, Jr., Receives Cushing Medal from AANS Ralph G. Dacey, Jr., M.D., has been awarded the Harvey Cushing Medal by the American Association of Neurological Surgeons (AANS). He was honored with the medal, the association’s most prestigious award, for his many years of outstanding leadership, dedication and contributions to the field of neurosurgery. The medal – named in honor of the father of modern neurosurgery – was awarded May 3, 2016 at the AANS annual meeting in Chicago. “It means a lot to me to be recognized by my peers,” said Dr. Dacey. He counts among his achievements the recruitment of outstanding clinicians and researchers to his department. “We’ve added great faculty and trained superb residents,” said Dacey. “We have some really innovative research being done here – for example, on the effective management of malignant brain tumors and spinal cord injuries, and on brain computer interfaces and complex cerebrovascular conditions.” Dr. Dacey is a former chairman of the American Board of Neurological Surgery and has served as president of the Congress of Neurological Surgeons, the American Academy of Neurological Surgeons, and the Society of Neurological Surgeons. He was elected to the Institute of Medicine of the National Academy of Sciences in

2010 and is an honorary fellow of the Royal College of Surgeons in Ireland. Founded in 1931 as the Harvey Cushing Society, the AANS is a scientific and educational association with more than 8,000 members worldwide. The AANS is dedicated to advancing the specialty of neurological surgery to provide the highest quality of neurosurgical care to patients.

Ralph G. Dacey Jr., M.D., (left) receives the Cushing Medal from H. Hunt Batjer, M.D., the 2015-16 president of AANS.

Departmental Promotions, Notable Appointments and Awards Eric Leuthardt, M.D., was promoted to Professor in November 2015. David Limbrick, M.D., Ph.D., was promoted to the role of Pediatric Division Chief in May 2016. Joshua Dowling, M.D., has been appointed as President of the Executive Council of the Southern

Neurosurgical Society Eric Arias, M.D., and Jarod Roland, M.D., earned “Top Gun” honors at the 2016 annual meeting of

the American Association of Neurological Surgeons (AANS).

Left to Right: Eric Arias, M.D., Kristopher Kimmell, M.D.,

and Jarod Roland, M.D.

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Meet the Interns

Rupen Desai, M.D., was born in Galveston, Texas, and comes to us from Duke University, where he obtained his undergraduate and M.D. degrees. In his down time, Rupen enjoys watching basketball (particularly his favorite Duke Blue Devils), playing intramural sports, cooking, exploring new restaurants, travelling, and reading. Anna Huguenard, M.D., was raised in Fort Wayne, Indiana, and attended Indiana University for her undergraduate training. She subsequently obtained her M.D. degree from Emory University. In her spare time, Anna enjoys running, hiking with her dog, playing volleyball, and reading. Peter Yang, M.D., was born in Albuquerque, New Mexico, and obtained his undergraduate degree from Johns Hopkins University. He then received his M.D. degree from Columbia University. In his free time, Peter enjoys playing the trombone, singing, playing volleyball, and cooking.

Left to Right: Peter Yang, M.D., Anna Huguenard, M.D.,

and Rupen Desai, M.D.

Profile of New Faculty Member: Joshua Osbun, M.D.

Joshua Osbun, M.D., with his

wife Alexandra and their dog Sawyer.

Joshua Osbun, M.D., will join the faculty of the Department of Neurological Surgery as an assistant professor in August 2016. He recently completed a fellowship in cerebrovascular surgery and interventional neuroradiology at Emory University after finishing his neurological surgery residency at the University of Washington in Seattle in 2014.

Dr. Osbun earned his medical degree at the University of Texas Southwestern Medical Center in Dallas and bachelor’s degrees in chemistry and English literature at Texas A&M University. He won several awards during his neurosurgery residency, including the “Courage to Lead Award” at the Department of Neurological Surgery, University of Washington.

Dr. Osbun’s clinic interests are in cerebrovascular surgery and endovascular neurosurgery, including the treatment of aneurysms, arteriovenous malformations, neurofistulas and ischemic stroke.

His research interests are outcomes in cerebrovascular surgery, stroke care and the genetics of aneurysms. Potential collaborators include Ralph Dacey, Jr., M.D., the Henry G & Edith R Schwartz Professor and chairman of neurological surgery; Gregory Zipfel, M.D., professor of neurological surgery; Christopher Moran, M.D., professor of radiology; and DeWitte Cross III, M.D., professor of radiology and director of interventional neuroradiology at Barnes-Jewish Hospital and St. Louis Children's Hospital. Away from work, Dr. Osbun likes to run, rock climb and ski.

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Ian Dorward, M.D., Albert Kim, M.D., Ph.D., Eric Leuthardt, M.D., and Greg Zipfel, M.D., are now seeing patients in the recently opened Center for Advanced Medicine-South County. The new 84,000-square-foot facility, situated several miles west of the primary medical campus, is close to Interstate 55, a main artery for the metropolitan area. The new center contains physician offices for neurosurgery and 14 other subspecialties, as well as radiology services, outpatient surgical suites and rehabilitative services. “The neurosurgeons caring for patients in our new center offer expertise in a number specialties,” says Gregory Zipfel, M.D., co-director of the Barnes-Jewish and Washing-

ton University Stroke and Cerebrovascular Center located on the main medical campus. “We want to offer patients convenient access and one-stop clinic visits by coordinating patient appointments with same-day radiology and imaging services,” says Dr. Zipfel. Patients requiring surgery, he adds, can be seen both pre- and post-operatively in the south county center; surgeries take place at Barnes-Jewish Hospital. The Center for Advanced Medicine-South County is located at 5201 Midamerica Plaza, near the intersection of I-55 and Butler Hill Road, in St. Louis, Missouri.

Neurosurgery at the Center for Advanced Medicine - South County

Left to Right: Albert Kim, M.D., Ph.D., Ian Dorward,

M.D., Eric Leuthardt, M.D., and Greg Zipfel, M.D.

Left to Right: Leticia Cross, N.P., Greg Zipfel, M.D., and

Rhonda Kidwell

New Pediatric Neurosurgery Fellow: Brandon Miller, M.D., Ph.D.

Brandon Miller, M.D., Ph.D., was born in Cleveland, Ohio. He completed his undergraduate degree at Washington University and obtained his M.D. and Ph.D. degrees from Ohio State University. He subsequently completed his Neurosurgery residency training at Emory University. In his spare time, he enjoys hiking, cycling, and reading American literature.

Brandon Miller, M.D., Ph.D., with his wife Monica


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The Pediatric Neuro-Oncology program at Washington University School of Medicine in St. Louis and St. Louis Children’s Hospital recently joined a prestigious network of the nation’s top childhood cancer centers. That development widens treatment options for children whose brain tumors don’t respond to standard care. The network, the Pacific Pediatric Neuro-Oncology Consortium, provides physicians with access to the latest technologies as well as clinical trials at its 15 medical centers, thereby expanding overall treatment options, and, ideally, patient success rates, said the program’s co-directors: the School of Medicine’s Joshua B. Rubin, M.D., Ph.D., professor of pediatrics and of neuroscience; and David D. Limbrick, M.D., Ph.D., an associate professor of neurological surgery and of pediatrics. Physicians and staff within the consortium can share data, expertise and resources regarding brain tumor biology and possible new treatments, said Rubin, who is also co-leader of the Solid Tumor Therapeutics Program for Washington University’s Siteman Cancer Center. “Being a part of the consortium brings cutting-edge brain tumor therapies to the children of St. Louis and the surrounding region.”

Added Limbrick: “As part of the consortium, we are better able to offer our patients the option of participating in clinical trials for personalized treatments for their brain tumors and to be part of the larger movement to understand the molecular basis of brain tumors.” The School of Medicine’s program offers individualized treatment plans through a multi-disciplinary approach that involves pediatric neuro-oncologists, neurosurgeons, radiation oncologists, radiologists, pathologists, endocrinologists, psychologists, social work, nurses and other specialty staff. The team meets weekly to evaluate every child’s unique needs. The neuro-oncology program provides top-of-the-line imaging technology and neurosurgical approaches. Children’s Hospital is one of the few pediatric medical centers that offers intraoperative MRI, considered a major advance in the treatment of brain tumors because it allows neurosurgeons to remove tumors more precisely, thanks to MRI images and computer guidance during surgery. The Pediatric Neuro-Oncology program is also the first to ever evaluate laser ablation surgery for pediatric brain tumors in a clinical trial.

School of Medicine joins Exclusive Pediatric Neuro-Oncology Consortium

Neurosurgery First-Year Medical Student Lab Day

March 15, 2016, marked the end of the first-year Medical Student Selective, run by Dr. Gavin Dunn. Each year the course is capped off with a cadaver lab. This year’s lab was graciously supported by Stryker. During the course, students do basic skull and spine dissections with introductory information about general neurosurgery cases. Over the past 2 years, the number of students taking the course has increased from 8 to 20, and the number of students that participate in the lab has met the maximum capacity of 40. This past year, faculty and resident participation in the cadaver lab were at an all-time high. Dr. Dunn was joined at the course by Drs. Albert Kim, Greg Zipfel, Jenn Strahle, Eric Arias, Bhuvic Patel, Jarod Roland, and Chester Yarbrough.

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New Grants Awarded: October 2015—May 2016


Zack Ray UM SCIRP “Diffusion basis spectrum imaging predicts neuroinflammation and axonal loss in acute and chronic spinal cord injury” 11/01/15 – 11/30/17 Jarod Roland R25 “Resting State MRI in Patients with Corpus Callosotomy Procedures in the Pediatric Population” 01/01/2016-06/30/2017 Itender Singh Brain Aneurysm Foundation “The role of cyclophilin A in blood-brain barrier, neuroinflammation and vasospasm after subarachnoid hemorrhage” 10/15/15 – 09/15/16 Jenn Strahle Pediatric Hydrocephalus Association “Mechanisms of Hydrocephalus after Intraventricular Hemorrhage” 12/01/15 – 11/30/16 Ananth Vellimana R25 “The Role of Cerebrovascular Microthrombosis in Delayed Cerebral Ischemia after Subarachnoid Hemorrhage” 07/01/2016 –6/30/2017 NREF “Activation of Endogenous Protective Mechanisms: A Potential Therapeutic Strategy to Combat SAH-induced Neurovascular Dysfunction “ 07/01/2016 –6/30/2017

Tom Beaumont NREF “Epigenetic Regulation of Hippocampal Epileptogenesis by the NuRD Complex” 07/01/2015-06/30/2016 Declined due to overlap with R25 Albert Kim Siteman Investment Program (SIP) “Regulation of glioblastoma stem-like cells by CDC20-Anaphase-Promoting Complex” 01/01/16 – 12/31/17 Dave Limbrick Patient-Centered Outcomes Research Institute (PCORI) “Posterior fossa decompression with or without duraplasty for Chiari type I malformation with syringomyelia” 11/01/15 – 08/31/19 Storz “Endoscopic, Navigation-Assisted Third Ventriculostomy with Choroid Plexus Cauterization: Developing a Surgically Relevant Model” 07/01/15 – 06/30/16 Pat McAllister Hydrocephalus Association “Therapeutic Modulation of Post-Hemorrhagic Hydrocephalus” 12/01/15 – 11/30/16 Medtronic “Endoscopic, Navigation-Assisted Third Ventriculostomy with Choroid Plexus Cauterization: Developing a Surgically Relevant Model” 01/14/16 – 01/13/17

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Publications (October 2015 - May 2016)


Neurosurg. 2016 Jan 15:1-11. [Epub ahead of print] Bumpass, DB, Buchowski, JM, Park, A., Gray, B.L., Agarwal, R., Baty, J., Zebala, L.P., Riew, K.D., Santiago, P., Ray, W.Z., and Wright, N.M. An Update on Civilian Spinal Gunshot Wounds: Treatment, Neurologic Recovery, and Complications. Spine 40(7):450-461, 2015. Bundy DT, Pahwa M, Szrama N, Leuthardt EC. Decoding three-dimensional reaching movements using electrocorticographic signals in humans. J Neural Eng. 2016 Apr;13(2):026021. doi: 10.1088/1741-2560/13/2/026021. Epub 2016 Feb 23. Dadey DY, Kapoor V, Khudanyan A, Urano F, Kim AH, Thotala D, Halla-han DE. The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma. Oncotarget. 2016 Jan 12;7(2):2080-92. doi: 10.18632/oncotarget.6712. Davis M, Awori J, Strahle J, Okechi H. Implications of patient-borne costs associated with pediatric neu-rosurgical care in Eastern Africa. J Neurosurg Pediatr. 2016 (PMID:26966883). Diringer MN, Dhar R, Scalfani M, Zazulia AR, Chicoine M, Powers WJ, Derdeyn CP. Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Sub-arachnoid Hemorrhage. Neurocrit Care. 2015 Dec 31. [Epub ahead of print]. Dlouhy B, Patel K, Woo A, Naidoo S, Smyth MD. Endoscopic-assisted management of sagittal synostosis: Wide vertex suturectomy and barrel stave osteotomies versus narrow vertex suturectomy. In press, Jour-nal of Neurosurgery: Pediatrics, April 2016. Dlouhy BJ, Smyth MD. Peri-insular Hemispherotomy. Neurosurgical

Operative Atlas: Functional Neuro-surgery, 3rd Edition. Gross RE and Boulis NM (eds). Thieme, NY, NY, 2016. Dorward IG, Buchowski JM, Stoker GE, Zebala LP. Posterior Cervical Fusion with Recombinant Human Bone Morphogenetic Protein-2: Complications and Fusion Rate at Minimum 2-Year Follow-Up. Clin Spine Surg. 2016 Jul;29(6):E276-81. doi: 10.1097/BSD.0b013e318286fa7e. Dunn GP. Shared decision-making for the elderly patient with a surgi-cal condition. Br J Surg. 2016 Jan;103(2):e19-20. doi: 10.1002/bjs.10076. Epub 2015 Dec 15. Dunn GP, Okada H. Principles of immunology and its nuances in the central nervous system. Neuro On-col. 2015 Nov;17 Suppl 7:vii3-vii8. doi: 10.1093/neuonc/nov175. Garton TP, He Y, Garton HJ, Keep RF, Xi G, Strahle JM. Hemoglobin-induced neuronal degeneration in the hippocampus after neonatal intraventricular hemorrhage. Brain Res. 1635:86-94, 2016 (PMID: 26772987). Godzik J, Ravindra VM, Ray WZ, Eskandari R, Dailey AT. Primary repair of open neural tube defect in adulthood: case example and re-view of management strategies. Spine J. 2015 Nov 1;15(11):e57-63. doi: 10.1016/j.spinee.2015.07.463. Epub 2015 Jul 30. Review. Greenberg JK, Ladner, TR, Guerroro N, Olsen MA, Shannon CN, Yar-brough CK, Piccirillo JF, Anderson R, Wellons JC, Smyth MD, Park TS, Limbrick DD. Chiari Malformation Type 1 Surgery in Children, Part 2: Complications and the Influence of Comorbid Disease in California, Florida, and New York. Journal of Neurosurgery:Pediatrics, 2016 Jan 22:1-8

Amin-Hanjani S, Pandey DK, Rose-Finnell L, Du X, Richardson D, Thulborn KR, Elkind MS, Zipfel GJ, Liebeskind DS, Silver FL, Kasner SE, Aletich VA, Caplan LR, Derdeyn CP, Gorelick PB, Charbel FT. Vertebro-basilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke Study Group. Effect of He-modynamics on Stroke Risk in Symptomatic Atherosclerotic Verte-brobasilar Occlusive Disease. JAMA Neurol. 2016 Feb;73(2):178-85. doi: 10.1001/jamaneurol.2015.3772. Arias EJ, Vajapey S, Reynolds MR, Chicoine MR, Rich KM, Dacey RG Jr, Dorward IG, Derdeyn CP, Moran CJ, Cross DT 3rd, Zipfel GJ, Dhar R. Utili-ty of Screening for Cerebral Vaso-spasm Using Digital Subtraction Angiography. Stroke. 2015 Nov;46(11):3137-41. doi: 10.1161/STROKEAHA.115.010081. Epub 2015 Sep 24. Bandt SK, Leuthardt EC. Minimally Invasive Neurosurgery for Epilepsy Using Stereotactic MRI Guidance. Neurosurg Clin N Am. 2016 Jan;27(1):51-8. doi: 10.1016/j.nec.2015.08.005. Epub 2015 Oct 24. Batra P, Bandt SK, Leuthardt EC. Resting state functional connectivi-ty magnetic resonance imaging integrated with intraoperative neu-ronavigation for functional mapping after aborted awake craniotomy. Surg Neurol Int. 2016 Feb 5;7:13. doi: 10.4103/2152-7806.175885. eCollection 2016. Beaumont, TL, Limbrick, DD, Rich, KM, Wippold FJII, Dacey, RGJ. Natu-ral History of Colloid Cysts of the Third Ventricle. J Neurosurg 2016 Mar 11:1-11. [Epub ahead of print]. Bi WL, Abedalthagafi M, Horowitz P, Agarwalla PK, Mei Y, Aizer AA, Brewster R, Dunn GP, Al-Mefty O, Alexander BM, Santagata S, Berou-khim R, Dunn IF. Genomic land-scape of intracranial meningiomas. J

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Kahle, K., Kulkarni, A.V., Limbrick, D.D.J., Warf, B.C. Hydrocephalus in children. Lancet 20;387(10020):788-99, 2016. Kang SK, Murphy RK, Hwang SW, Lee SM, Harburg DV, Krueger NA, Shin J, Gamble P, Cheng H, Yu S, Liu Z, McCall JG, Stephen M, Ying H, Kim J, Park G, Webb RC, Lee CH, Chung S, Wie DS, Gujar AD, Vemula-palli B, Kim AH, Lee KM, Cheng J, Huang Y, Lee SH, Braun PV, Ray WZ, Rogers JA. Bioresorbable silicon electronic sensors for the brain. Nature. 2016 Feb 4;530(7588):71-6. doi: 10.1038/nature16492. Epub 2016 Jan 18. Kang P, Raya A, Zipfel GJ, Dhar R. Factors Associated with Acute and Chronic Hydrocephalus in Nonaneu-rysmal Subarachnoid Hemorrhage. Neurocrit Care. 2016 Feb;24(1):104-9. doi: 10.1007/s12028-015-0152-7. Kestle, JRW, Riva-Cambrin, J, Butler, J, Browd, SR, Drake, JM, Holubkov, R, Kulkarni, AV, Limbrick, DD, Si-mon, TD, Tamber, M, Wellons, JC III, Whitehead, WE. for the Hydroceph-alus Clinical Research Network. A New Hydrocephalus Clinical Re-search Network Protocol to Reduce Cerebrospinal Fluid Shunt Infection. J Neurosurg Pediatr 2015 Dec 18:1-6. [Epub ahead of print]. Kruse CA, Pardo-Villamizar C, Hart-man A, Vining EPG, Voros J, Gaillard WD, Liu J, Oluigbo C, Malone S, Micati A, Rodrigues Velasco T, Ma-chada H, Martino AM, Huang A, Wheatley BM, Grant G, Granata T, Freri E, Koh S, Nordli D, Rainha Campos A, O’Neill B, Handler MH, Chapman KE, Wilfong AA, Curry DJ, Yaun A, Madsen J, Goldenberg M, Smyth MD, Mercer D, Vinters HV, Tung S, Erickson KL, Huynh MN, Chang JW, Malone C, Cepeda C, Levine MS, Chirwa T, Owens GC, Mathern GW. Rasmussen encepha-litis tissue transfer program. In press, Epilepsia, March 2016. Gamble P, Stephen M, MacEwan M,

Ray WZ. Serial Assessment of Func-tional Recovery Following Nerve Injury Utilizing Implantable Thin-Film Wireless Nerve Stimulators. Muscle Nerve. 2016 Apr 22. doi: 10.1002/mus.25153. [Epub ahead of print]. Greenberg JK, Olsen MA, Yarbrough CK, Ladner TR, Shannon CN, Picciril-lo JF, Anderson RC, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr. Chiari malformation Type I surgery in pediatric patients. Part 2: compli-cations and the influence of comor-bid disease in California, Florida, and New York. J Neurosurg Pediatr. 2016 May;17(5):525-32. doi: 10.3171/2015.10.PEDS15369. Epub 2016 Jan 22. Ladner TR, Greenberg JK, Guerrero N, Olsen MA, Shannon CN, Yar-brough CK, Piccirillo JF, Anderson RCE, Feldstein NA, Wellons JCIII, Smyth MD, Park TS, Limbrick, DDJ. Chiari Malformation Type I Surgery in Pediatric Patients. Part 1: Valida-tion of an ICD-9 Code Search Algo-rithm. J Neurosurg Pediatr 2016 Jan 22:1-6. [Epub ahead of print]. Lee MH, Miller-Thomas MM, Ben-zinger TL, Marcus DS, Hacker CD, Leuthardt EC, Shimony JS. Clinical Resting-state fMRI in the Preopera-tive Setting: Are We Ready for Prime Time? Top Magn Reson Imag-ing. 2016 Feb;25(1):11-8. doi: 10.1097/RMR.0000000000000075. Leonard JR, Limbrick DD. Chiari I Malformation: Adult and Pediatric Considerations. Neurosurg Clin N Am 2015 Oct;26(4):xiii-xiv. doi: 10.1016/j.nec.2015.07.002.

Greenberg JK, Yarbrough CK, Rad-manesh A, Godzik J, Yu M, Jeffe DB, Smyth MD, Park TS, Piccirillo JF, Limbrick DD Jr. In Reply: Chiari Se-verity Index: A Novel Grading Sys-tem Intended for Preoperative Counseling. Neurosurgery. 2015 Nov;77(5):E842. doi: 10.1227/NEU.0000000000000936. Gujar AD, Yano H, Kim AH. The CDC20-APC/SOX2 signaling axis: An achilles' heel for glioblastoma. Mol Cell Oncol. 2015 Aug 20;3(3):e1075644. doi: 10.1080/23723556.2015.1075644. eCollection 2016 May. Hawasli AH, Chang J, Yarbrough CK, Steger-May K, Lenke L. Dorward IG. Interpedicular height as a predictor of radicular pain in adult degenera-tive scoliosis. The Spine Journal. May 2. pii: S1529-9430(16)30067-5. Holekamp TF, Mollman ME, Murphy RK, Kolar GR, Kramer NM, Derdeyn CP, Moran CJ, Perrin RJ, Rich KM, Lanzino G, Zipfel GJ. Dural arterio-venous fistula-induced thalamic dementia: report of 4 cases. J Neu-rosurg. 2016 Jun;124(6):1752-65. doi: 10.3171/2015.5.JNS15473. Epub 2015 Nov 20. Huang J, Campian JL, Gujar AD, Tran DD, Lockhart AC, DeWees TA, Tsien CI, Kim AH. A phase I study to re-purpose disulfiram in combination with temozolomide to treat newly diagnosed glioblastoma after chemoradiotherapy. J Neurooncol. 2016 Jun;128(2):259-66. doi: 10.1007/s11060-016-2104-2. Epub 2016 Mar 10. Johanns TM, Fu Y, Kobayashi DK, Mei Y, Dunn IF, Mao DD, Kim AH, Dunn GP. High incidence of TERT mutation in brain tumor cell lines. Brain Tumor Pathol. 2016 Mar 9. [Epub ahead of print].

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Kelly MP, Santiago P, Zebala LP, Trinkaus K, Ray WZ,Song SK. Frac-tional anisotropy to quantify cervi-cal spondylotic myelopathy severi-ty. J Neurosurg Sci. 2016 May 5. Murphy RK, Sun P, Xu J, Wang Y, Sullivan S, Gamble P, Wagner J, Wright NN, Dorward IG, Riew D, Santiago P, Kelly MP, Trinkaus K, Ray WZ, Song SK. Magnetic Reso-nance Imaging Biomarker of Axon Loss Reflects Cervical Spondylotic Myelopathy Severity. Spine (Phila Pa 1976). 2016 May;41(9):751-6. doi: 10.1097/BRS.0000000000001337. Pahwa M, Kusner M, Hacker CD, Bundy DT, Weinberger KQ, Leuthardt EC. Optimizing the Detec-tion of Wakeful and Sleep-Like States for Future Electrocortico-graphic Brain Computer Interface Applications. PLoS One. 2015 Nov 12;10(11):e0142947. doi: 10.1371/journal.pone.0142947. eCollection 2015. Price RL, Harkins L, Chiocca EA, Zhang PJ, Kurt H, Iwenofu OH. Hu-man Cytomegalovirus is Present in Alveolar Soft Part Sarcoma. Appl Immunohistochem Mol Morphol. 2016 Mar 17. [Epub ahead of print]. Ravindra VM, Bollo R, Sivakumar W, Akbari H, Naftel RP, Limbrick DD, Jea A, Gannon SR, Shannon C, Bir-kas Y, Yang GL, Prather CT, Kestle J, Riva-Cambrin J. Predicting blunt cerebrovascular injury in pediatric trauma: Validation of the "Utah Score". J Neurotrauma. 2016 Jun 13. [Epub ahead of print]. Ray WZ, Schmidt MH. Thoracoscop-ic Vertebrectomy for Thoracolum-bar Junction Fractures and Tumors: Surgical Technique and Evaluation of the Learning Curve. Clin Spine Surg. 2016 May 2. [Epub ahead of print].

Ray WZ, Akbari SH, Shah L, Bisson EF. Correlation of Foraminal Area and Response to Cervical Nerve Root Injections. cureus.com Ray WZ, Chang K, Hawasli A, Wilson TJ, Yang L. Motor Nerve Transfers: A Comprehensive Review. Neurosur-gery. 2016 Jan; 78(1):1-26. Reynolds MR, Singh I, Azad TD, Holmes BB, Verghese PB, Dietrich HH, Diamond M, Bu G, Han BH, Zipfel GJ. Heparan sulfate proteo-glycans mediate Aβ-induced oxida-tive stress and hypercontractility in cultured vascular smooth muscle cells. Mol Neurodegener. 2016 Jan 22;11:9. doi: 10.1186/s13024-016-0073-8. Reynolds MR, Buckley RT, In-drakanti SS, Turkmani AH, Oh G, Crobeddu E, Fargen KM, El Ahmad-ieh TY, Naidech AM, Amin-Hanjani S, Lanzino G, Hoh BL, Bendok BR, Zipfel GJ. The safety of vasopressor-induced hypertension in subarach-noid hemorrhage patients with coexisting unruptured, unprotected intracranial aneurysms. J Neuro-surg. 2015 Oct;123(4):862-71. doi: 10.3171/2014.12.JNS141201. Epub 2015 Jul 24. Riva-Cambrin J, Browd SR, Drake JM, Holubkov R, Kestle JRW, Kul-karni AV, Limbrick DD, Rozzelle CJ, Simon TD., Tamber, M., Wellons, J.C. III, Whitehead, WE. for the Hy-drocephalus Clinical Research Net-work. Risk factors for shunt mal-function in pediatric hydrocephalus: A multi-center prospective cohort study. J Neurosurg Pediatr 2015 Dec 4:1-9. [Epub ahead of print] Roland J, Ray W.,Leuthardt E. Youmans and Winn Neurological Surgery. 7th edition. Neuropros-thetics.

Leuthardt EC, Allan M, Kamran M, Hawasli AH, Snyder AZ, Hacker CD, Mitchell TJ, Shimony JS. Resting-State Blood Oxygen Level-Dependent Functional MRI: A Para-digm Shift in Preoperative Brain Mapping. Stereotactic and Func-tional Neurosurgery. 2015;93(6):427-39. Leuthardt EC, Duan C, Kim MJ, Cam-pian JL, Kim AH, Miller-Thomas MM, Shimony JS, Tran DD. Hyper-thermic Laser Ablation of Recurrent Glioblastoma Leads to Temporary Disruption of the Peritumoral Blood Brain Barrier. PLoS One. 2016 Feb 24;11(2):e0148613. doi: 10.1371/journal.pone.0148613. eCollection 2016. MacEwan MR, Talcott MR, Moran DW, Leuthardt EC. Novel spinal instrumentation to enhance osteo-genesis and fusion: a preliminary study. J Neurosurg Spine. 2016 Apr 15:1-10. [Epub ahead of print]. Mangano, FT, Altaye, M., McKinstry, RC, Shimony, J.S., Powell, S.K., Phil-lips, J.M., Barnard, H., Limbrick, D.D.J., Holland, S.K., Jones, B.V., Dodd, J., Simpson, S., Mercer, D., Rajagopal, A., Bidwell, S., Yuan, W. DTI study of Children with Congeni-tal Hydrocephalus: 1 Year Post-Surgical Outcomes. J Neurosurg Pediatr 2016 May 20:1-14. Murata T, Dietrich HH, Horiuchi T, Hongo K, Dacey RG Jr. Mechanisms of magnesium-induced vasodilation in cerebral penetrating arterioles. Neurosci Res. 2016 Jun;107:57-62. Murphy R, He Y, Janjua M, Schuerer D, Ray W, Wright N. Hyperacute Stabilization (<12 hours) for Poly-trauma Patients with Unstable Spi-nal Fracture. J. Neurosurg Sci. Epub ahead of print 2015. Murphy RK, Sun P, Han RH, Griffin KJ, Wagner JM, Yarbrough CK, Wright NM, Dorward IG, Riew DK,

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I malformation. J Neurosurg Pedi-atr. 17(4):403-9, 2016 (PMID: 26636249). Strahle J, Selzer B, Geh N, Srinivasan D, Strahle M, Martinez M, Muraszko KM, Garton HJ, Maher CO. Sports participation with arachnoid cysts. J Neurosurg Pediatr. 17(4):410-17, 2016 (PMID: 26636254). Sun SQ, Cai C, Murphy RK, DeWees T, Dacey RG, Grubb RL, Rich KM, Zipfel GJ, Dowling JL, Leuthardt EC, Simpson JR, Robinson CG, Chicoine MR, Perrin RJ, Huang J, Kim AH. Radiation Therapy for Residual or Recurrent Atypical Meningioma: The Effects of Modality, Timing, and Tumor Pathology on Long-Term Outcomes. Neurosurgery. 2016 Jul;79(1):23-32. Sylvester PT, Moran CJ, Derdeyn CP, Cross DT, Dacey RG, Zipfel GJ, Kim AH, Uppaluri R, Haughey BH, Tempelhoff R, Rich KM, Schneider J, Chole RA, Chicoine MR. Endovascu-lar management of internal carotid artery injuries secondary to endo-nasal surgery: case series and re-view of the literature. J Neurosurg. 2016 Jan 15:1-21. [Epub ahead of print]. Tarawneh R, D'Angelo G, Crimmins D, Herries E, Griest T, Fagan AM, Zipfel GJ, Ladenson JH, Morris JC, Holtzman DM. Diagnostic and Prog-nostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease. JAMA Neurol. 2016 May 1;73(5):561-71. doi: 10.1001/jamaneurol.2016.0086. Vaubel RA, Chen SG, Raleigh DR, Link MJ, Chicoine MR, Barani I, Jen-kins SM, Aleff PA, Rodriguez FJ, Burger PC, Dahiya S, Perry A, Gian-nini C. Meningiomas With Rhabdoid Features Lacking Other Histologic Features of Malignancy: A Study of 44 Cases and Review of the Litera-ture. J Neuropathol Exp Neurol. 2016 Jan;75(1):44-52. doi: 10.1093/

jnen/nlv006. Epub 2015 Dec 7. Re-view. Washington CW, Derdeyn CP, Dhar R, Arias EJ, Chicoine MR, Cross DT, Dacey RG Jr, Han BH, Moran CJ, Rich KM, Vellimana AK, Zipfel GJ. A Phase I proof-of-concept and safety trial of sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage. J Neurosurg. 2016 Feb;124(2):318-27. doi: 10.3171/2015.2.JNS142752. Epub 2015 Aug 28. Wright NM, et al. Spinal Sealant System Provides Better Intraopera-tive Watertight Closure than Stand-ard of Care during Spinal Surgery: A Prospective, Multi-Center, Random-ized Controlled Study. Spine 40(8):505-13, 2015. Yarbrough CK, Bommarito KM, Gamble PG, Hawasli AH, Dorward IG, Olsen MA, Ray WZ. Population-based approaches to treatment and readmission after spinal cord injury. J Neurosurg Sci. 2016 Mar 3. Yarbrough CK, Gamble PG, Janjua MB, Tang M, Ghenbot R, Zhang AJ, Juknis N, Hawasli AH, Kelly MP, Ray WZ. Readmission after Spinal Cord Injury: Analysis of an Institutional Cohort of 795 Patients. J Neurosurg Sci. 2016 May 6. Yuan W, Holland SK, Shimony JS, McKinstry RC, Altaye M, Mangano FT, Limbrick DD, Jones BV, Nash T, Rajagopal A, Simpson S, Ragan D, McKinstry RC. Abnormal Structural Connectivity in the Brain Networks of Children with Hydrocephalus. Neuroimage: Clinical 8:483-92, 2015.

Roland J, Smyth MD. Vagal Nerve Stimulation. Masters of Neurosur-gery, Samandouras (ed), 2015. Roland JL, Smyth M. Masters of Neurosurgery. Insertion of a vagal nerve stimulator for refractory epi-lepsy. Rumalla K, Yarbrough CK, Pugely AJ, Koester L, Dorward IG. Spinal fusion for pediatric neuromuscular scolio-sis: national trends, complications, and in-hospital outcomes. J Neuro-surg Spine. 2016 May 20:1-9. [Epub ahead of print]. Salehi A, Ott K, Skolnick GB, Nguyen DC, Naidoo SD, Kane AA, Woo AS, Patel KB, Smyth MD. Neosuture formation after endoscope-assisted craniosynostosis repair. J Neurosurg Pediatr. 2016 Apr 29:1-5. [Epub ahead of print]. Schwetye KE, Joseph NM, Al-Kateb H, Rich KM, Schmidt RE, Perry A, Gutmann DH, Dahiya S. Gliosarco-mas lack BRAFV600E mutation, but a subset exhibit β-catenin nuclear localization. Neuropathology. 2016 Mar 2. doi: 10.1111/neup.12293. [Epub ahead of print]. Smyth MD, Vellimana AK, Asana E, Sood S. Corpus Callosotomy: Open and endoscopic surgical techniques. Epilepsia, in press 2016. Song S, Miranda CJ, Braun L, Meyer K, Frakes AE, Ferraiuolo L, Likhite S, Bevan AK, Foust KD, McConnell MJ, Walker CM, Kaspar BK. Major histo-compatibility complex class I mole-cules protect motor neurons from astrocyte-induced toxicity in amyo-trophic lateral sclerosis. Nat Med. 2016 Apr;22(4):397-403. doi: 10.1038/nm.4052. Epub 2016 Feb 29. Strahle J, Geh N, Selzer B, Bower R, Himedan M, Strahle M, Wetjen N, Muraszko KM, Garton HJ, Maher CO. Sports participation with Chiari

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National & International Presentations

(October 2015—May 2016)

Dacey, R. Neurosurgical Decision Making: Indica-tions and Operative Techniques. Grand Rounds, Emory University Visiting Professor, October 29, 2015, Atlanta, Georgia. Dacey, R. Career Channels in Cerebrovascular Sur-gery. Tindall Distinguished Lecture, Emory Universi-ty Department of Neurosurgery, October 29, 2015, Atlanta, GA. Dacey, R. Brain Networks and Your Golf Swing. Gulf Stream Country Club, Gulf Stream, Florida, March 21, 2016. Dacey, R. Leadership/Team Building/Conflict Reso-lution. Society of Neurological Surgeons Resident Boot Camp, April 15, 2015, PASE, St. Louis, MO. Dacey, R. Microsurgical Management of Intracranial Aneurysms: Site-specific Surgical Anatomy, Opera-tion Intervention and Complication Management. American Association of Neurological Surgeons Annual Meeting, May 1, 2016, Chicago, IL. Dewan, M.C., Ravindra, V.M., Gannon, S., Prather, C.T., Yang, G.L., Limbrick, D., Jea, A., Riva-Cambrin, J., Naftel, R.P. Treatment Practices and Outcomes Following Blunt Cerebrovascular Injury in Children. AANS/CNS Section on Pediatric Neurosurgery, Seat-tle, WA, December, 2015. Domeshek L, Skolnick G, Naidoo S, Proctor M, Smyth MD, Patel K, Woo A. Pre- to postoperative changes in orbital dysmorphology in unicoronal craniosynostosis following endoscopic repair. Platform presentation, ACPA, Atlanta, GA April 4-9, 2016. Habiyaremye, G., Morales, D., Morgan, C.D., McAl-lister, J.P., Mercer, D., Limbrick, D.D. Differentia-tion of Cerebrospinal Fluid Inflammatory Bi-omarkers between Neonatal Post-hemorrhagic and Congenital Hydrocephalus . Seventh Meeting of the International Society for Hydrocephalus and CSF Disorders, Banff, Alberta, CA, September, 2015. Habiyaremye, G., Morales, D., Morgan, C.D., McAl-lister, J.P., Mercer, D., Limbrick, D.D. Novel Cere-brospinal Fluid Inflammatory Biomarkers in Neona-tal Post-hemorrhagic Hydrocephalus. Seventh Meet-ing of the International Society for Hydrocephalus and CSF Disorders, Banff, Albert, CA, September, 2015.

Habiyaremye, G., Morales, D.M., Morgan, C.D., McAllister, J.P., Mercer, D., Limbrick, D.D.J. Neuroinflammation in Hydrocephalus is Etiology-Specific. AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015. Hankinson, T., Tuite, G., Moscoso, D., Robinson, Torner, J., Limbrick, D.D.J., Park T.S., Anderson, R.C.E. for the Park-Reeves Syringomyelia Research Consortium Investigators. Analysis and inter-rater reliability of pB-C2 measurements using T1 MRI, T2 MRI, and CT images in pediatric patients with Chiari I malformation and syringomyelia: Data from the Park Reeves Syringomyelia Research Consortium (PRSRC). AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015. Gabiyaremye, G., Morales, D.M., Morgan, C.D., McAllister, J.P., Mercer, D., Limbrick, D.D. Post-hemorrhagic and Congenital Hydrocephalus Differential Expression of Cere-brospinal Fluid Inflammatory Biomarkers. AANS/CNS Sec-tion on Pediatric Neurosurgery, Seattle, WA, December, 2015. Gauvain, K., Tran, D., Rubin, J., Campian, J., Leuthardt, E., Limbrick, D.D.J. A pilot study of using MRI-guided laser heat ablation to induce disruption of the peritumoral blood brain barrier to enhance delivery and efficacy of treatment of pediatric brain tumors. International Sympo-sium on Pediatric Neuro-Oncology (ISPNO), June, 2016. Harpster, K., Powell, S.K., Weckherlin, N., Barnard, H.D., Kadis, D.S., Dodd, J.N., Engsberg, J., Simpson, S.M., Bid-well, S., Mangano, F.T., Limbrick, D.D., Altaye, M., Yuan, W. Detecting White Matter Alterations in Response to a 6-week Occupational Therapy Intervention in Children with Hydrocephalus: a Preliminary DTI Study. ASNR, May, 2016, Washington, D.C. Jeong. A., Strahle J., Vellimana. A., Limbrick. D.D., Smyth. M.D., Bertrand. M. Hemispherotomy in children with elec-trical status epilepticus of sleep. Child Neurology Society Annual Meeting, 2016. Limbrick, D.D.J. More Complicated than A-B-C: a Formida-ble Cervical Aneurysmal Bone Cyst. American Society for Pediatric Neurosurgery, Palm Beach, Aruba, January, 2016. Limbrick, D.D.J., Morales, D.M., Morgan, C., Rantfle, M., Mercer, D., Wallendorf, M., McAllister, J.P. Cerebrospinal Fluid Amyloid Precursor Protein Levels are Diagnostic of Infantile Congenital Hydrocephalus. AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015.

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National & International Presentations cont.

Masserano, B., Skolnick, G., Naidoo, S., Proctor, M., Smyth, M.D., Patel, K., Woo, A. Evaluation of the temporal region in unilateral coronal craniosynosto-sis after fronto-orbital advancement or endoscopic-assisted strip craniectomy and cranial orthotic ther-apy. Platform presentation, ACPA, Atlanta GA April 4-9, 2016. McAllister, J.P., Guerra, M., Rodriguez, E., Morales, D.M., Limbrick, D.D.J. Ventricular Zone Disruption in Human Post-Hemorrhagic Hydrocephalus. AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015. Morgan, C.D., Morales, D.M., Habiyaremye, G., McAllister, J.P.II, Limbrick, D.D. Cerebrospinal Fluid Biomarkers of Malfunctioning Shunts: A Pilot Study. Seventh Meeting of the International Society for Hydrocephalus and CSF Disorders, Banff, Alberta, CA, September, 2015. Ragan, D.K., Shimony, J., Yuan, W., Altaye, M., McKinstry, R.C., Jones, B.V., Mangano, F.T., Holland, S., Limbrick, D.D.J. Deep gray matter alterations in congenital hydrocephalus measured with diffusion MRI. AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015. Riva-Cambrin, J., Kestle, J., Reeder, R., Holubkov, R., Alvey, J., Limbrick, D., Tamber, M., Browd, S., Whitehead, W., Simon, T., Wellons, J., Naftel, R., Shannon, C., Cochrane, D., Rozelle, C., Kulkarni, A.V. ETV-CPC success and evolving indications and tech-nique over time: An HCRN study. AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015. Santiago, P. The 22nd Advanced Techniques in Cer-vical Spine Decompression & Stabilization. Practical Anatomy and Surgical Education. St. Louis, MO. Sept 10-12, 2015. Santiago, P. 9th Annual CSRS Cervical Spine Decom-pression & Stabilization Techniques. Practical Anat-omy and Surgical Education. St. Louis, MO. Feb 18-20, 2016.

Shah, M.D., Mitra, A., Goyal, M.G., Snyder, A.Z., Shimony, J.S., Limbrick, D.D., Raichle, M.E., Smyth, M.D. Functional Connectivity Signal Latency Predicts Laterality in Pediatric Medically-Refractory Temporal Lobe Epilepsy. American Society for Pediatric Neurosurgery, Palm Beach, Aruba, January, 2016. Simon, T.D., Kronman, M., Gove, N., Whitlock, K., Browd, S., Holubkov, R., Kestle, J., Kulkarni, A., Langley, M., Lim-brick, D., Luerssen, T., Oakes, J., Riva-Cambrin, J., Rozzelle, C., Shannon, C., Tamber, M., Wellons, J., Whitehead, W., Hamblett, N. Surgical approach to treatment of first cere-brospinal fluid (CSF) shunt infection is associated with reinfection. Pediatric Academic Societies meeting, May 3, 2016, Baltimore, MD. Sindhoora, M., Skolnick, G., Huang, Z., Naidoo, S., Patel, K., Tao, J., Smyth, M.D., Woo, A. Long-term characterization of cranial defects after surgical correction for single-suture craniosynostosis. Platform presentation, ACPA, Atlanta GA April 4-9, 2016. Smyth, M.D.. Close Calls in Craniofacial Surgery: Dodging Bullets. ASPN Annual Meeting, Aruba Feb 4th, 2016. Strahle, J.M., Vellimana, A., Jeong, A., Bertrand, M., Lim-brick, D.D., Smyth, M.D. Outcomes after hemispherotomy for ESES (Electrical Status Epilepticus During Sleep). AANS/CNS Joint Pediatric Section annual meeting, Seattle, WA, Dec 10, 2015. Strahle, J., Vellimana, A., Jeong, A., Bertrand, M., Limbrick, D.D.J., Smyth, M.D. Outcomes after hemispherotomy for ESES (electrical status epilepticus during sleep). AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, Decem-ber, 2015. Strahle, J., Smith, B., Muraszko, K.M., Garton, H.J.L., Ma-her, C.O. Differential contributions of syrinx size and tonsil position to the presence and magnitude of scoliosis in Chiari I malformation. American Association of Neurologi-cal Surgeons, 84th annual meeting, Chicago, IL, 2016. Tamber, M.S., Kulkarni, A.V., Riva-Cambrin, J., Holubkov, R., Browd, S., Cochrane, D., Drake, J., Limbrick, D., Roz-zelle, C., Simon, T., Wellons, J., Whitehead, W., Kestle, J. Hydrocephalus Clinical Research Network (HCRN) Shunt Infection Protocol Implementation Across Pediatric Neuro-surgery - A Cross-Sectional Survey. AANS/CNS Section on Pediatric Neurosurgery, Seattle, WA, December, 2015.

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National & International Presentations cont.

Wright, N. Cervical Facet Dislocations. 12/2/15, Cervical Spine Research Society 20th Annual In-structional Course, San Diego, CA. Wright, N. Cervical Arthroplasty: Indications vs Fu-sion, Available Devices. 9/3/15, 22nd Advanced Techniques in Cervical Decompression and Stabili-zation, St. Louis, MO. Yu, J.L., Patel, K.B., Skolnick, G.B., Naidoo, S.D., Parikh, R.P., David, L.R., Couture, D.E., Smyth, M.D., Woo, A.S. Comparison of two endoscopic sagittal craniosynostosis repair techniques: spring-assisted surgery versus craniectomy with helmet molding therapy. AAPS Annual Meeting, 2016. Yu, J., Skolnick, G., Naidoo, S., Couture, D., Parikh, R., David, L., Smyth, M.D., Patel, K., Woo, A. Com-parison of two endoscopic sagittal craniosynostosis repair techniques: spring-assisted surgery vs crani-ectomy with helmet molding therapy. Platform presentation, ACPA, Atlanta GA April 4-9, 2016. Zipfel, G. Using Milestones to Identify and Manage

the “Problem Resident”. Course – RRC Next Accreditation System, Milestones, and the Neurosurgery Matrix. Con-gress of Neurological Surgeons Annual Meeting, New Or-leans, LA, September 26, 2015. Zipfel, G. Brain Aneurysms and Vascular Malformations. French Academy of Surgery Symposium, Department of Surgery, Washington University, St. Louis, MO, October 7, 2015. Zipfel, G. The Future of Departments of Neurosurgery in Academic Medical Centers. Special Lecture. Department of Neurological Surgery, University of Minnesota, Minneap-olis, MN, October 26, 2015. Zipfel, G. Vascular contributors to dementia: The underap-preciated role of cerebral amyloid angiopathy. Grand Rounds, Department of Neurology, Washington Universi-ty, St. Louis, MO, December 4, 2015. Zipfel, G. The Promise of Conditioning-Based Therapy for Aneurysmal Subarachnoid Hemorrhage. The Center for Brain Hemorrhage Research Lecture Series, Loma Linda University, Los Angeles, CA, December 9, 2015.

Meg Williams, MSN, RN - Patient Safety Nurse Coordinator

Debra Grochowalski, RN - Dr. Ian Dorward

Leticia Cross, NP - Dr. Greg Zipfel

New Department of Neurosurgery Staff

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P E R S O N

W H O W A S

J U S T

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T R A I N E D "


Personal News

Drs. Tom and Najla Beaumont welcomed their first child, son

Sebastian, on April 25, 2016 (Sebastian is pictured here with Ellie Ray).

Department of Neurological Surgery

660 South Euclid

Campus Box 8057

St. Louis, Missouri 63110

Phone: (314) 362-3570

Fax: (314) 362-2107

www.neurosurgery.wustl.edu

Upcoming Events

September 24-September 28, 2016 - CNS Meeting

October 26, 2016 - Annual William S. Coxe Lecture

January 21, 2017 - 11th Annual Research Symposium

March 17, 2017 - ABNS Primary Exam

April 22-April 26, 2017 - AANS Meeting

May 10, 2017 - Annual Park Lecture

June 3, 2017 - Annual Softball Tournament in New York City

July 1, 2017 - Start of New Academic Year

Neurosurgery Frontiers highlights the professional and personal accomplishments of the faculty and residents of the Department of Neurological

Surgery at Washington University School of Medicine. Faculty and residents are encouraged to submit their updates to the Neurosurgery

Residency Coordinator, Sophie Church ([email protected]) for inclusion in the newsletter.

Neurosurgery Frontiers is published semi-annually.

w a s h i n g t o n neurosurgery frontiers · neurological surgery at the university of washington,...

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