www.copd-conference.co.uk Register online or fax your registration to +44 (0) 870 9090 712 or call +44 (0) 870 9090 711

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@SMIPHARM

SMi Present the 8th Annual Conference on…

COPDHoliday Inn Kensington Forum, London, UK

19 - 20

OCT2016

Modelling Future Needs to Adapt Your Novel Therapeutics and Management Strategies

Featured Sessions in 2016: • Predicting drug effi cacy using integrative models

for chronic respiratory diseases • New approaches for COPD drug development:

An opportunity for disease interception • Advances in device and formulation technologies

for pulmonary drug delivery

Chairs: • Professor Gary P. Anderson PhD FThorSoc FERS, Chief

Scientist, Respiratory Infl ammation and Autoimmunity iMed, AstraZeneca, and Founding Director, Lung Health Research Centre, University of Melbourne

• Professor Donna Davies, Professor of Respiratory Cell and Molecular Biology, University of Southampton

Featured Speakers: • Stephen Beckman, Head of Global Respiratory

and Allergy, Mylan, Inc. • Dr Neelima Khairatkar Joshi, Sr Vice President,

Glenmark Pharmaceuticals • Dr Mario Scuri, Head Respiratory Unit,

Chiesi Pharmaceuticals • Dr Frank Thielmann, Lead Inhalation New Solids,

Novartis Pharma AG • Dr Christopher Stevenson, Venture Leader, COPD

Interception, Janssen Pharmaceutical Companies of Johnson & Johnson

• Dr Jonathan Phillips, Principal Scientist, Amgen • Dr Beverley Patterson, Inhalation Clinical Associate

Director, Actavis • Dr Donna K Finch, Principal Scientist, MedImmune LtdWhat past attendees say:

“Very good conference, experienced speakers…”

“Very focused and easy to exchange information”

“It is an excellent two day event. I have learned quite a lot of new things... a well-rounded conference!”

COPDDay One | Wednesday 19th October 2016

8.30 Registration & Coffee

9.00 Chairman’s Opening Remarks

Professor Gary P. Anderson PhD FThorSoc FERS,

Chief Scientist, Respiratory Infl ammation and

Autoimmunity iMed, AstraZeneca, and Founding Director,

Lung Health Research Centre, University of Melbourne

OPENING ADDRESS

9.10 Predicting drug effi cacy using integrative models for

chronic respiratory diseases

• Animal models are vital instruments of the drug

discovery process

• Novel bioinformatics methods

• Innovative physiological techniques

Dr Jonathan Phillips, Principal Scientist, Amgen

9.50 Blood eosinophils in COPD

• Signifi cance of blood eosinophils

• Scientifi c evidence

• The way forward

Dr Mario Scuri, Head Respiratory Unit, Chiesi

Pharmaceuticals

10.30 Morning Coffee

11.00 CASE STUDY: Patient selection strategies for

clinical development of biologic drugs for COPD

• Using patient selection strategies in COPD

• Early clinical case studies using clinical phenotype,

blood and lung biomarkers

Dr Donna Finch, Principal Scientist, MedImmune Ltd

11.40 Session reserved for Glenmark Pharmaceuticals

Dr Neelima Khairatkar Joshi, Sr Vice President, Glenmark

Pharmaceuticals

12.20 Networking Lunch

1.30 Recent advances in drug development & treatment of COPD

• Treatment options • Drug development strategies • Insilco and PKPD modeling in the development of

respiratory drugs Dr Beverley Patterson, Inhalation Clinical Associate

Director, Actavis

2.10 Deconvoluting bioactive biomarkers to understand the pathogenesis of COPD exacerbations

Professor Gary P. Anderson PhD FThorSoc FERS, Chief Scientist, Respiratory Infl ammation and Autoimmunity iMed, AstraZeneca, and Founding Director, Lung Health Research Centre, University of Melbourne

2.50 Afternoon Tea

3.20 myCOPD an advanced patient self-management and rehabilitation platform

• An introduction to online self management • Online vs. paper self management/class base

pulmonary rehabilitation • myCOPD an international real-time patient platform to

deliver population level care and research Dr Simon Bourne, CEO, my Mhealth Limited

PANEL DISCUSSION4.00 Developing clinical trials for COPD • The overview of endpoints used in COPD trials • Patient selection and recruitment • Future recommendations Professor Gary P. Anderson PhD FThorSoc FERS,

Chief Scientist, Respiratory Infl ammation and Autoimmunity iMed, AstraZeneca, and Founding Director, Lung Health Research Centre, University of Melbourne

Dr Jonathan Phillips, Principal Scientist, Amgen Dr Mario Scuri, Head Respiratory Unit,

Chiesi Pharmaceuticals Dr Donna Finch, Principal Scientist, MedImmune Ltd Dr Neelima Khairatkar Joshi, Sr Vice President,

Glenmark Pharmaceuticals

4.40 Chairman’s Closing Remarks and Close of Day One

PRE-CLINICAL & CLINICAL DEVELOPMENT COPD EXACERBATIONS

Supported by

Register online at www.copd-conference.co.uk

SPONSORSHIP AND EXHIBITION OPPORTUNITIESSMi offer sponsorship, exhibition, advertising and branding packages, uniquely tailored to complement your company’s marketing strategy. Prime networking

opportunities exist to entertain, enhance and expand your client base within the context of an independent discussion specifi c to your industry. Should you wish to join the increasing number of companies benefi ting from sponsoring our conferences please call:

Alia Malick on +44 (0) 20 7827 6168 or email: amalick@smi-online.co.uk

MARKETING OPPORTUNITIESWant to know how you can get involved? Interested in promoting your services to this market?

Contact Anna Serazetdinova, SMi Marketing on +44 (0) 207 827 6180 or email: aserazetdinova@smi-online.co.uk

Offi cial media partner: Offi cial Publications

ADVANCES IN PATIENT MONITORING

COPDDay Two | Thursday 20th October 2016

8.30 Registration and Coffee

9.00 Chairman’s Opening Remarks Professor Donna Davies, Professor of Respiratory Cell and

Molecular Biology, University of Southampton

OPENING ADDRESS9.10 COPD products: Trends and challenges • Drivers and penetration across different markets

• Therapeutic positioning and need for cost savings

• Effect of competition fi rst to market opportunities

Stephen Beckman, Head of Global Respiratory and

Allergy, Mylan, Inc.

9.50 New approaches for COPD drug development: An opportunity for disease interception

• Current therapies with long-acting bronchodilators and

inhaled corticosteroids

• Alternative anti-infl ammatories and bronchodilators

• COPD interception: A new promising approach?

Dr Christopher Stevenson, Venture Leader, COPD

Interception, Janssen Pharmaceutical Companies of Johnson & Johnson

10.30 Morning Coffee

11.00 Solithromycin is a next-generation oral and intravenous fl uoroketolide

• Profi le of solithromycin

• In vitro and in vivo studies

• Small Phase II clinical trial of oral solithromycin in patients

Dr Glenn Tillotson, Senior Vice President of Medial Affairs,

Sempra Inc.

11.40 Advances in device and formulation technologies for pulmonary drug delivery

• State of the art formulation strategy and technologies

• Relevant physicochemical properties and how to

measure them

• Device – formulation interaction

• Trends in device development

Dr Frank Thielmann, Lead Inhalation New Solids, Novartis Pharma AG

12.20 Networking Lunch

KEYNOTE ADDRESS

1.30 Mechanisms of virus-induced COPD exacerbations and

novel treatment strategies

• Innate immune responses to viral infection in airways

disease

• The phenotype of COPD epithelium

• Inhaled interferon-beta for treatment of COPD

exacerbations

Professor Donna Davies, Professor of Respiratory Cell and

Molecular Biology, University of Southampton

2.10 Vitamin E isoform �-tocotrienol protects against cigarette

smoke-induced experimental COPD

• Oxidative stress and damage in COPD

• Free radical-neutralizing capability of �-tocotrienol

• Anti-infl ammatory properties of �-tocotrienol

Dr Fred Wong, Head & Associate Professor, Department

of Pharmacology, National University of Singapore

2.50 Afternoon Tea

3.20 Cholinergic signalling, tiotropium and lung immunology:

Impacts on COPD and asthma treatment

• Cholinergic signalling and the immune system

• Impact on airway disease

• Potential novel drug targets

Dr Corinna Schnoeller, Research Associate,

Imperial College London

4.00 Chairman’s Closing Remarks and Close of Day Two

DRUG DEVELOPMENT & NOVEL TARGETS

Supported by

Alternatively fax your registration to +44 (0)870 9090 712 or call +44 (0)870 9090 711

MARKETING OPPORTUNITIESWant to know how you can get involved? Interested in promoting your services to this market?

Contact Anna Serazetdinova, SMi Marketing on +44 (0) 207 827 6180 or email: aserazetdinova@smi-online.co.uk

2015 Attendees By Region

Join Us as a Sponsor:

• Showcase you brand and product in a professional and independent setting, when our delegates are in a receptive and engaging mindset

• Reach decision-makers from the leading pharmaceutical companies

• Network during the panel debate and round table discussion

• Build brand awareness and product recognition

Tailored Sponsorship Packages Include:

• Lead Sponsor• Lunch/Coffee Break Sponsor• Exhibitor/Booth Sponsor• Speaking Sponsor• Drinks Reception Sponsor• Promotional Literature Distribution• Banner/Stand• Lanyards

UK – 43%

Europe – 30%

USA – 23% Other – 4%

2015 Attendees Profi le By Sector

Pharma – 58.8%

Consultancy – 17.6%

Academia – 13.7%

Technology companies – 9.9%

SMi PharmceuticalEvent Planner

JUNE

ADMET13th - 14th JuneHoliday Inn KensingtonForum, London, UK Immunogenicity13th - 14th JuneHoliday Inn KensingtonForum, London, UK

BioBanking20th - 21st JuneHoliday Inn KensingtonForum, London, UK

JULY

Lyophilisation Europe4th - 5th JulyHoliday Inn KensingtonForum, London, UK

Allergies6th - 7th July Holiday Inn KensingtonForum, London, UK

Peptides6th - 7th JulyHoliday Inn KensingtonForum, London, UK

SEPTEMBER

Cancer Vaccines21st - 22nd September London, UK Biosimilars Europe29th - 30th SeptemberLondon, UK

OCTOBER European Market Access, Pricing & Reimbursement in Pharma10th - 11th OctoberLondon, UK Orphan Drugs19th - 20th OctoberLondon, UK

NOVEMBER

Superbugs & Superdrugs USA14th - 15th NovemberNew Jersey, USA Biosimilars USA16th - 17th NovemberNew Jersey, USA 3d Cell Culture28th - 29th NovemberLondon, UK

DECEMBER

Cold Chain Distribution12th - 13th DecemberLondon, UK

SPONSORSHIP AND EXHIBITION OPPORTUNITIESSMi offer sponsorship, exhibition, advertising

and branding packages, uniquely tailored

to complement your company’s marketing

strategy. Prime networking opportunities

exist to entertain, enhance and expand

your client base within the context of

an independent discussion specifi c to

your industry. Should you wish to join the

increasing number of companies benefi ting

from sponsoring our conferences please

call: Alia Malick on +44 (0) 20 7827 6168 or

email: amalick@smi-online.co.uk

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Payment: If payment is not made at the time of booking, then an invoice will be issued and must be paid immediately and prior to the start of the event. If payment has not been received then credit card details will be requested and payment taken before entry to the event. Bookings within 7 days of event require payment on booking. Access to the Document Portal will not be given until payment has been received.Substitutions/Name Changes: If you are unable to attend you may nominate, in writing, another delegate to take your place at any time prior to the start of the event. Two or more delegates may not ‘share’ a place at an event. Please make separate bookings for each delegate.Cancellation: If you wish to cancel your attendance at an event and you are unable to send a substitute, then we will refund/credit 50% of the due fee less a £50 administration charge, providing that cancellation is made in writing and received at least 28 days prior to the start of the event. Regretfully cancellation after this time cannot be accepted. We will however provide the conferences documentation via the Document Portal to any delegate who has paid but is unable to attend for any reason. Due to the interactive nature of the Briefi ngs we are not normally able to provide documentation in these circumstances. We cannot accept cancellations of orders placed for Documentation or the Document Portal as these are reproduced specifi cally to order. If we have to cancel the event for any reason, then we will make a full refund immediately, but disclaim any further liability.Alterations: It may become necessary for us to make alterations to the content, speakers, timing, venue or date of the event compared to the advertised programme.Data Protection: The SMi Group gathers personal data in accordance with the UK Data Protection Act 1998 and we may use this to contact you by telephone, fax, post or email to tell you about other products and services. Unless you tick here □ we may also share your data with third parties offering complementary products or services. If you have any queries or want to update any of the data that we hold then please contact our Database Manager databasemanager@smi-online.co.uk or visit our website www.smi-online.co.uk/updates quoting the URN as detailed above your address on the attached letter.

Payment must be made to SMi Group Ltd, and received before the event, by one of the following methods quoting reference P-187 and the delegate’s name. Bookings made within 7 days of the event require payment on booking, methods of payment:

□ UK BACS Sort Code 300009, Account 00936418

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VAT at 20% is charged on the attendance fees for all delegates. VAT is also charged on Document portal and literature distribution for all UK customers and for those EU Customers not supplying a registration number for their own country here. ______________________________________________________________________________________

If you have any further queries please call the Events Team on tel +44 (0) 870 9090 711 or you can email events@smi-online.co.uk

□ Book by 30th June to receive £400 off the conference price□ Book by 31st August to receive £200 off the conference price□ Book by 30th September to receive £100 off the conference price

EARLY BIRD DISCOUNT

I would like to attend: (Please tick as appropriate) Fee Total

□ Conference only £1499.00 + VAT £1798.80

PROMOTIONAL LITERATURE DISTRIBUTION □ Distribution of your company’s promotional

literature to all conference attendees £999.00 + VAT £1198.80

The conference fee includes refreshments, lunch, conference papers, and access to the Document Portal. Presentations that are available for download will be subject to distribution rights by speakers. Please note that some presentations may not be available for download. Access information for the document portal will be sent to the e-mail address provided during registration. Details are sent within 24 hours post conference.

□ Please contact me to book my hotelAlternatively call us on +44 (0) 870 9090 711, email: events@smi-online.co.uk or fax +44 (0) 870 9090 712

I cannot attend but would like to purchase access to the following Document Portal/paper copy documentation Price Total□ Access to the conference documentation

on the Document Portal £499.00 + VAT £598.80□ The Conference Presentations – paper copy £499.00 - £499.00

(or only £300 if ordered with the Document Portal)

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Our Reference LVP-187

DELEGATE DETAILS

Terms and Conditions of Booking

PAYMENT

VAT

CONFERENCE PRICES

DOCUMENTATION

VENUE Holiday Inn Kensington Forum, 97 Cromwell Rd, London SW7 4DN, UK

COPDConference: Wednesday 19th - Thursday 20th October 2016, Holiday Inn Kensington Forum, London, UK

4 WAYS TO REGISTERwww.copd-conference.co.uk

FAX your booking form to +44 (0) 870 9090 712PHONE on +44 (0) 870 9090 711

POST your booking form to: Events Team, SMi Group Ltd, 2nd Floor South, Harling House, 47-51 Great Suffolk Street, London, SE1 0BS, UK