introduction to asepsis

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    Infection- is an invasion of body tissue bymicroorganisms and their growth there. Thus,

    the microorganism is called as infectiousagent

    Disease- a detectable alteration in normaltissue function.

    Virulence- refers to the severity and degree adisease can produce.

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    Asepsis- freedom from disease causingmicroorganisms.

    2 types:

    a. Medical asepsis- includes all practices to

    confine a MO to a specific area limiting thenumber and growth of MO

    b. Surgical asepsis- practices that keep anarea free from MO, destroys all MO andspores.

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    Types of MO causing infections

    Bacteria- most common infection causingMO.

    Virus- consists of nucleic acid and must enterliving cells to reproduce

    Fungi- include yeast and molds

    Parasites- live on other living MO

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    Types of infections

    Local infection- is limited to the specific partof the body where MO remain.

    Systemic infection- MOs spread and damage

    different parts of the body.

    Acute infections- appear suddenly or last a shorttime

    Chronic infections- may occur slowly, over a longperiod may last months or years.

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    Nosocomial infections

    - Infections that are associated with delivery ofhealth care services in a health care facility.

    Most common MOs

    a.E.coli- urinary tract

    b.Pseudomonas- surgical sites

    c.Enterococcus- blood stream

    d.Staphylococcus- Pneumonia

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    CHAIN OF INFECTION

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    CHAIN OF INECTION1. Etiologic agent- the extent to which any MO

    is capable of producing an infectiousprocess depends on:

    a. # of MOsb. Virulence and potency of MOs

    c. Ability of MO to enter the body

    d. Susceptibility of the hoste. Ability of MO to live inside the body

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    2. Reservoir- (sources) of MOs

    e.g. Humans, plants, animals or general

    environment.

    Carrier- a person or animal reservoir of specific

    agent that does not manifest any clinicalsigns of disease.

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    3.Portal of exit- before an infection canestablish itself in a host, the MO must leave

    the reservoir.e.g.

    BODY RESERVOIR PORTALS OF EXIT

    a.

    Resp. tract

    b. GI tract

    c. Urinary tract

    -Nose or mouth troughsneezing, coughing, etc.

    -Mouth:Saliva, feces,vomitus

    -Anus:feces, urethralmeatus

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    BODY RESERVOIR PORTALS OF EXIT

    d. Reproductive tract

    e. Blood

    f. Tissue

    -Vagina: vaginal discharge

    -Open wound, needle

    puncture

    -Drainage from cut orwound

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    4. Method of Transmission

    3 mechanisms:1. Direct- involves immediate and direct transfer of

    MO from person to person through touching,biting, kissing or sexual intercourse.

    2. Indirect:

    a. Vehicle borne- fomites

    b. Vector borne- insects

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    3. Airborne- involves droplets or dust.

    5. Portal of Entry- before a person can becomeinfected, MO must enter the body.

    6. Susceptible host- any person who is at riskfor infection.

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    Inflammation

    Is a local and nonspecific defensive responseof the tissues to an injurious or infectiousagent.

    Characterized by 5 signs:

    - Pain, swelling, redness, heat and impaired

    function.

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    END

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