PILOT SCALE TECHNIQUE FORGINGER OIL FROM GINGER

BYAVS. PRAVEEN KUMAR

I M.PHARMACY

• PLANT: It is considered as the place where material,men,method and machine are brought together for the manufacturing of products.

• PILOT SCALEUP: It refers to the art of designing a lab scale formula for the production.

PILOT SCALE TECHNIUE

Definition:

A pilot plant allows investigation of a product and process on an intermediate scale before large amounts of money are committed to full-scale production.

WHY TO CONDUCT PILOT PLANT STUDIES

• A pilot scale up technique is an intermediate scale for estimation & assessment of a product and process on before huge amounts of money invest for large scale production.

• It is not possible to design a large scale processing plant from laboratory data alone with any degree of success.

GINGER OIL

GINGER OIL PROCESSING

Collection & Cultivation. Extraction. Analysis. PACKING & STORAGE.

GINGER OIL

• Ginger oil is essential oil that is extracted from the plant ginger i.e Zingiberaceae officinale of the Zingiberaceae family and is also known as Common or Jamaica Ginger.

GINGER OIL PROPERTIES

• Ginger oil is pale yellow in color, has a fresh, agreeable & aromatic smell, has strong and characteristic odour.

• The shelf life of Ginger oil is very long and it is Stable at room temperature.

• So it is used in aromatherapy also in fragrance therapy.

CHEMICAL CONSTITUENTS OF GINGER OIL

Zingiberine 35%ᵝ sesquiphellandrene 10%Bisa Bolene 8%Dexto-camphene 6%Beta-phellandrene 3%1,8-cineole 2%Others 26%

Chemial structures:6-gingerolzingeberene

8-gingerolzingiberol

USES OF GINGER OILThe health benefits of ginger oil is

Digestive, Carminative, Expectorant, Antiseptic, Analgesic, Anti pyretic, Simulating and aphrodisiac properties.

These benefits of ginger oil include its ability to treat stomach problems, nausea, indigestion, inflammations, respiratory & Heart problems, menstrual disorders, etc.

CULTIVATION & COLLECTION

Cultivated area & Yield in India: Cultivated States: Climate, Rain fall and Altitude: Soil : Fertilizers & Manures: Sowing Rhizomes is done in the month of June Harvesting is Done after 6th months i.e. in December,

January, when the colour in lite buff. Max yield:

TYPES IN DRYING

Ground dried ginger. Fresh sliced ginger (0% dryness).

Dried sliced ginger (90% dryness).

Dryness (%) = Initial weight of sample (g) - Current weight of sample Dryness (%) (g)|x 100 Initial weight (g)

EXTRACTION

Methods Used For Extraction Of Oil:

•Infusion•Maceration•Percolation•Soxhlation•Soxtec•M.A. E•Ultra Sonication•Spouted Bed ExtractionSteam Distillation:Super Critical Fluid Extraction (SFE):•R.P.E•MPSLE

The pilot scale water distillation unit

Condenser

Dean stark

Separating funnel

Pressure cooker

The water and steam distillation unit at CLEAR

SUPERCRITICAL FLUID EXTRACTION (SFE)

TLC PROFILE OF GINGER OIL

Sample detail : Ginger Oil ( Zingiber officinale )

Adsorbent : Precoated silicagel

Mobile Phase : Toulene : Ethyl Acetate (93:7)

Sample preparation : 1 gm of Zingiber officinale oil was

dissolved in chloroform and 10ml applied

on the TLC plate.

Solvent front run upto : 9 cms

Detection : Anisaldihyde Sulphuric acid reagent (Fig.1)

Vanillin sulphuric acid (Fig.2).

Scanning : 254 nm

Fig. 1

Fig. 2Rf. = 0.9 – Zingiberene (red spot)

~

Storage & Packing

References:

1. Pharmacognosy, by Dr.C.K. Kokate , A.P. Purohit,S.B. Gokhale Nirali

Prakashan, 38 th edition, 2007.

2. Qulity control of herbal drugs by Pollok Mukhergy

3. Wagner H, et al, Plant Drug Analysis, Spinger, 1996, 300

4.British Pharmacopoeia, 305

5. Indian Standard Specification for Oil of Ginger, 1st Revision.

6. Herbal Drug Technology by Prof S.S Agarwal 7. Online library wiley.com

THANK YOU