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MouseMonitor™ S Surgical Monitoring An integrated approach can help your lab achieve consistent outcomes, increase survival rates & satisfy your IACUC Product Workshop, Experimental Biology 2014 1 Presenter: Graham Sattler Director of Product Development Indus Instruments

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MouseMonitor™ S

Surgical MonitoringAn integrated approach can help your lab achieve consistent outcomes, increase survival rates & satisfy your IACUC

Product Workshop, Experimental Biology 20141

Presenter: Graham SattlerDirector of Product DevelopmentIndus Instruments

MouseMonitor™ S Product Workshop, Experimental Biology 20142

1) Surgical Monitoring2) Integrated Physiologic Monitoring3) MouseMonitor S Capabilities4) Focus on Ease of Use

Overview

MouseMonitor™ S Product Workshop, Experimental Biology 20143

Section 1) Surgical Monitoring

1) Surgical Monitoring• Why Surgical Monitoring?• Sketch of a Surgery• IACUC Surgical Requirements• Surgical Monitoring & Me• Repeatability is Key

2) Integrated Physiologic Monitoring

3) MouseMonitor S Capabilities

4) Focus on Ease of Use

MouseMonitor™ S Product Workshop, Experimental Biology 20144

How does it add value to my research?

Why Surgical Monitoring?

• Increase Survival Rates• Increase Surgical Consistency• Reduce Study Variability• Satisfy IACUC Requirements

MouseMonitor™ S Product Workshop, Experimental Biology 20145

Goal: Achieve a Specific Outcome

Sketch of a Surgery

• Induce Anesthesia• Stabilize & Maintain

Anesthesia• Prepare Subject & Surgical

Site• Perform Surgical Procedure• Recovery from Anesthesia

MouseMonitor™ S Product Workshop, Experimental Biology 20146

Research Protocol Requirements Increasing

IACUC Surgical Requirements

• More Monitoring• Non-Invasive Methods• Better Heating• More Documentation

MouseMonitor™ S Product Workshop, Experimental Biology 20147

Researchers Have Many Responsibilities

Surgical Monitoring & Me

• Researcher• Anesthesiologist• Surgeon• Quality Control Officer• IACUC Compliance Officer

Monitoring Helps You at Every Step

MouseMonitor™ S Product Workshop, Experimental Biology 20148

Surgical Monitoring Reduces Variability

Repeatability is Key

• Provide a Stable Preparation• Spot Potential Problems Earlier• Improve Survival Rates

Doesn’t this already exist

In the clinical space?

MouseMonitor™ S Product Workshop, Experimental Biology 20149

Section 2) Integrated Physiologic Monitoring

1) Surgical Monitoring

2) Integrated Physiologic Monitoring• Integrated Physiologic Monitoring?• Brief History of Physiologic

Monitors• Clinical Monitoring Benefits• What The Guide Says• A Preclinical First• Researcher Observations

3) MouseMonitor S Capabilities

4) Focus on Ease of Use

MouseMonitor™ S Product Workshop, Experimental Biology 201410

What is it?

Integrated Physiologic Monitoring?

• Compact Presentation of Vital Signs• Easy to Use Information• Actionable Information

MouseMonitor™ S Product Workshop, Experimental Biology 201411

You’ve Come a Long Way Baby

Brief History of Physiologic Monitors

• Timeline• Decade Highlights

MouseMonitor™ S Product Workshop, Experimental Biology 201412

Outcome Improvements Drove Adoption

Clinical Monitoring Benefits

• Increased Survival Rates• Increased Surgical

Consistency• Decreased Recovery Costs

Better Patient Outcomes

MouseMonitor™ S Product Workshop, Experimental Biology 201413

Preclinical Recommendations Mirror Clinical

What The Guide Says

• NRC’s Guide for the Care and Use of Laboratory Animals• Adopted by all Laboratory Animal Care Organizations• Driving Increased IACUC Requirements

MouseMonitor™ S Product Workshop, Experimental Biology 201414

Integrated Physiologic Monitoring with the MouseMonitor S

A Preclinical First

• Harness Clinical Advancements• Reduce Mortality• Improve Surgical

Consistency• Identify Problems Faster• Research Focused

Features

MouseMonitor™ S Product Workshop, Experimental Biology 201415

Section 3) MouseMonitor S Capabilities

1) Surgical Monitoring

2) Integrated Physiologic Monitoring

3) MouseMonitor S Capabilities• Non-Invasive Monitoring• Responsive Heating• Rigid Surgical Platform• Research Quality Data• Easy Study & IACUC Documentation

4) Focus on Ease of Use

MouseMonitor™ S Product Workshop, Experimental Biology 201416

Rodent Integrated Physiologic Monitoring

Non-Invasive Monitoring

• Surface Electrodes• Rectal Probe• Thigh or Foot Clip

MouseMonitor™ S Product Workshop, Experimental Biology 201417

An Intelligent Heating Solution

Responsive Heating

• Zone-Based Electronic Heating• Reaches Temperature 10x

Faster• Animal Safety is our Priority

MouseMonitor S Competitor'sBlanket

0

5

10

15

20

25

Minutes to Reach 39°C Set Temperature

MouseMonitor™ S Product Workshop, Experimental Biology 201418

Designed for Rodent Surgery

Rigid Surgical Platform

• Rigid, Stable Work Surface• Easily Cleanable & Sterilizable• Enough Space to Rest Hands

MouseMonitor™ S Product Workshop, Experimental Biology 201419

Data – it’s what research is all about

Research Quality Data

• High Resolution Signals• Low Noise Electronics Design• Non-interfering Modalities• Full Resolution Analog Output

MouseMonitor™ S Product Workshop, Experimental Biology 201420

Easily Tell your Research Story

Easy Study & IACUC Documentation

• Screenshots• Recordings & Playback

MouseMonitor™ S Product Workshop, Experimental Biology 201421

Easy Study & IACUC Documentation

MouseMonitor™ S Product Workshop, Experimental Biology 201422

Easy Study & IACUC Documentation

MouseMonitor™ S Product Workshop, Experimental Biology 201423

Easy Study & IACUC Documentation

MouseMonitor™ S Product Workshop, Experimental Biology 201424

Easy Study & IACUC Documentation

MouseMonitor™ S Product Workshop, Experimental Biology 201425

Section 4) Focus on Ease of Use

1) Surgical Monitoring

2) Integrated Physiologic Monitoring

3) MouseMonitor S Capabilities

4) Focus on Ease of Use• Designed for Daily Stress-Free Use• At-A-Glance Monitoring• A Powerful Research Tool• Flexibility & Value

MouseMonitor™ S Product Workshop, Experimental Biology 201426

The Day is Already Short Enough

Designed for Daily Stress-Free Use

• Quick Setup• Touch User Interface• Powerful Presets

MouseMonitor™ S Product Workshop, Experimental Biology 201427

Capture and Publish Quality Data

A Powerful Research Tool

• Capture Valuable Data• Spend Less Time

on IACUC Compliance

MouseMonitor™ S Product Workshop, Experimental Biology 201428

Increased Surgical Quality & Survival Rate

Researcher Observations

The MouseMonitor S is a complete and effective tool to view physiological parameters and they have proven extremely effective. Our survival rate has gone up, and the quality of our surgeries has also improved.

– Max Z.

What MouseMonitor S Customers are Saying

MouseMonitor™ S Product Workshop, Experimental Biology 201429

Great Surgical Monitoring Solution

Researcher Observations

The MouseMonitor S has been a great addition to the Mouse Phenotyping Core, we use it for monitoring the mice and maintaining body temperature during various surgical procedures. It has proven to be a very effective and cost-efficient alternative to telemetry but it still provides excellent ECG signals from all three leads.

– Corey R., Ph.D.

What MouseMonitor S Customers are Saying

MouseMonitor™ S Product Workshop, Experimental Biology 201430

Easy to Use & Quality ECG

Researcher Observations

We are very impressed by the ease of use and the quality of the ECG signals and R trigger.

– Mathieu P., Ph.D.

What MouseMonitor S Customers are Saying

MouseMonitor™ S Product Workshop, Experimental Biology 201431

A Wide Range of Capabilities

Flexibility & Value

• Many Applications• Grows with Your Lab• Great Value

MouseMonitor™ S Product Workshop, Experimental Biology 201432

Supports All Phases of Your Research

Conclusion

• Integrated Physiologic Monitor• Responsive Heater• Rigid Surgical Platform• Research Quality Data• Easy Documentation

MouseMonitor™ S Product Workshop, Experimental Biology 201433

Improves Surgical Outcomes

Conclusion

• Increases Survival Rates• Increases Surgical

Consistency• Reduces Study Variability• Simplifies IACUC Compliance

MouseMonitor™ S Product Workshop, Experimental Biology 201434

Contact Info: Graham SattlerDirector of Product [email protected]: (281) 286-1130

Company Website: www.mousemonitor.com/ebwith Webinars & More Product Info

Questions & Contact

See and Touch the MouseMonitor S Today

Come See Us at Our Booth:Experimental Biology Booth #1546