institutional animal care and use committee (iacuc)
DESCRIPTION
Institutional Animal Care and Use Committee (IACUC). The IACUC provides internal oversight of animal: - husbandry - facilities - use in teaching & research. The ASU IACUC consists of 11 voting members plus other supporting participants who include: - PowerPoint PPT PresentationTRANSCRIPT
Institutional Animal Care and Use Committee (IACUC)Institutional Animal Care and Use Committee (IACUC)
The IACUC provides internal oversight of animal:- husbandry- facilities- use in teaching & research
The ASU IACUC consists of 11 voting members plus other supporting participants who include:
- faculty representing the various departments and uses of animals
- representatives of relevant ASU service departments
- DACT (including the Attending Veterinarian)
- EH&S- Campus Health- VPREA Office- Risk Management
- non-affiliated member
http://researchintegrity.asu.edu/
Institutional Animal Care and Use Committee (IACUC)Institutional Animal Care and Use Committee (IACUC)
animalsiacuc
Web site includes:- Policy and Procedure Manual
- forms
- training instructions and exams
- Occupational Health & Safety Program documents
- Standard Institutional Guidelines
- protocol due dates & meeting dates
- Animal Welfare Assurance & USDA certificate numbers
- society non-traditional species guidelines
- AVMA euthanasia guidelines
- federal regulations
- etc.
Last year’s 2 aims as the new Chair:
1) To assure that ASU meets all regulatory requirements
- USDA – enforces the Animal Welfare Act. Definition of “animal”?
- OLAW (Office of Laboratory Animal Welfare) – oversees the use of non-human vertebrates in PHS-supported research (PHS Policy on Humane Care and Use of Laboratory Animals, 2002)
- AAALACi (Association for the Assessment & Accreditation of Laboratory Animal Care International) – voluntary, covers all non-human vertebrates at the institution
- U.S. Fish & Wildlife Service – oversees federally protected species and international transport of all vertebrate animals and their parts
- Arizona Game & Fish Department – oversees the capture & holding of native wildlife, as well as the holding of restricted non-native wildlife
- Arizona Department of Health Services – covers species where there is a concern for zoonotic disease
Institutional Animal Care and Use Committee (IACUC)Institutional Animal Care and Use Committee (IACUC)
March 5-6, 2009
October 28-29, 2009All mammals except laboratory mice & rats
Institutional Animal Care and Use Committee (IACUC)Institutional Animal Care and Use Committee (IACUC)
Last year’s 2 aims as the new Chair:
2) To minimize the burden on investigators (provided it does not interfere with Aim 1)
- Require IACUC training and certification specific to the investigator, not the protocol.
- Eliminate the need for duplicative protocols in situations where a PI conducts work at multiple local institutions.
- ??
Name Title
Role in Protocol (What procedures will each person be doing?)
Species with which individual will have direct contact (“all” or list species)*
IACUCUSE ONLY Training(mm/yy)
Dale DeNardo Associate Professor
PI, no procedures
none
Joe Shmoe Graduate Student
all rats, mice
ASU-BNI agreement
Institutional Animal Care and Use Committee (IACUC)Institutional Animal Care and Use Committee (IACUC)
The review process (details in the Policy & Procedure Manual):
Protocols:- pre-reviewed by the Attending Veterinarian, then one other IACUC member (assigned by the Chair as the Primary Reviewer)- reviewed by the full committee at a convened meeting in the presence of the PI or designee
Amendments:- Minor – administratively approved by the Chair- Significant – with the approval of the full committee, reviewed by a Designated Reviewer (assigned by the Chair) and the Attending Veterinarian- Major – reviewed by full committee at a convened meeting
- the rationale for the new procedure is consistent with the research goals in the approved protocol
- involves no increased risk of pain, distress, or discomfort to animals
- does not markedly increase, by absolute or relative terms, the number of animals involved in the project
- a change that does not in any way effect the animals
Changes to the Protocol FormChanges to the Protocol Form
- section for Additional Contact information
- split the literature search into two separate searches
- duplicative research
- alternatives to animal use and painful procedures
- includes section to summarize results
- pay close attention to the search words used
- method of animal identification, if any
Regulatory oversight is very dynamic, expect more changes!
- qualifications and training of all participants (in protocols and added in an amendment)
Why were there changes?
MAKE SURE TO USE THE MOST CURRENT FORM! (available on the web site)