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Drug Study
Classification Mechanisms
of Action
Indication Contraindication Adverse
Effects
Nursing
Responsibilities
Ampicillin Anti-infective Interferes
with cell wall
synthesis of
susceptible
organism,
preventing
bacterial
multiplication
Deactivated
by beta-
lactamase,an enzyme
produced by
resistant
bacteria.
Treatment of
respiratory
tract and soft
tissue
infection,
bacterial
meningitis,
septicemia
and
gonococal
infections
caused by
susceptible
microorganis
ms
Hypersensitivi
ty to penicillins,
cephalosporins
or imipenem
Oral form not
used to treat
severe
pneumonia,
bacteremia,
pericarditis,
purulent or septicarthritis during
acute stage
Thro
mbophle
bitis at
injection
site
Irritabi
lity
Skin
rashes
Itchy
eyes
Laryn
gospasm
Laryn
geal
edema
Diarrh
ea
Obtain patient
history of infection
before and during
therapy to assess
response
Assess patient for
signs and
symptoms of
infection, fever,
characteristics of
wounds, sputum,urine, stool, ear
ache, and WBC
count
Obtain CNS
before drug
therapy to identify
if correct
treatment has
been initiated
Assess for
allergic or
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hypersensitivity
reactions: chills,
fever, joint pain,
pruritus and rash.
Monitor renal
function: urine
output, urinalysis:
protein and blood.
Assess for over
growth of
infection: perineal
itching, fever,
malaise, redness,
pain, swelling,
drainage, rash,diarrhea, or
change in
character of
cough and
sputum.
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Classification Mechanisms
of Action
Indication Contraindication Adverse
Effects
Nursing
Responsibilities
Gentamicin Anti-infective Interfere
s with proteinsynthesis inbacterial cellby binding toribosomalsubunit,causingmisreading ofgenetic code;inaccuratepeptidesequenceforms inprotein chain,causingbacterialdeath
Interferes
with proteinsynthesisin bacterialcell bybinding toribosomalsubunit,causingmisreadingof geneticcode;inaccuratepeptidesequenceforms inproteinchain,causingbacterialdeath
Hypersensitivit
y to gentamicinInjury andulceration of thecornea, viralinfection ormycosis
Headache
Fever
Muscleweaknessandtwitching
Acuteorganicbrainsyndrome
Rash
Itching
Anaphylaxis
Apnea
Anemia
Assess
patient forprevioussensitivityreacyion
Assesspatient for signsand symptoms ofinfection
Assess forallergic reaction:rash, chills, fever
Identify urineoutput
Monitor forbleeding
Monitor inputoutput
Assess fordehydration
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Classification Mechanisms
of Action
Indication Contraindication Adverse
Effects
Nursing
Responsibilities
Vitamin K Clotting
vitamin/agent
Vitamin K
is fat soluble
vitamin that
plays an
important
role in blood
clotting
For those
with
vitamin K
deficiency.
In patients
receiving
anticoagulants as
vitamin K decreas
the effects of the
drugs
Decreased
appetite,
decreases
movement
or activity;
difficult in
breathing,
enlarged
liver,
general
body
swimming,muscle
stiffness,
yellow
eyes or
skin.
Difficulty in
swallowing
; fast or
irregular
breathing;
lightheade
dness or
If you take
warfarin(a blood
thinner, you should
know that vitamin k
or food containing
vitami k can affect
the the drug
Vitamin K
deficiency is very
rare. It occurs when
the cody cantproperl absorb the
vitamihn from the
intestinal tract
Vitamin k deficiency
can also occur after
long term treatment
with antibiotics
If you are taking
anticoagulantmedicines(bloodthi
nners), the amount
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Classification Mechanisms
of Action
Indication Contraindication Adverse
Effects
Nursing
Responsibilities
Fusidic acid Opthalmic
Prparations
Inhibits
bacterial
photosynthe
sis; it does
not bind to
the bacterial
ribosomes
but inhibits
the factor
necessary
for
translocation of peptide
subunits
and
elongation
of the
peptide
chain;
bacteriostati
c or
bactericidal
Treatm
ent of
staphyloco
ccal
infections,
often in
conjunction
with other
drugs
Hypersensitivi
ty
Hypers
ensitivity
reactions
in the form
of rashes
and
irritation
may occur
after the
topical
administra
tion offusidates;
rash is
rare after
systemic
administra
tion
Obtain
patients history
including
hypersensitivity
Assess the
patient for signs
and symptoms of
infection including
characteristics of
wounds, urine,
stool, ear ache,fever; obtain
baseline
information before
and during
treatment
Perform
periodic
monitoring of liver
function test
Monitor
hypocalcaemia
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Classification Mechanisms
of Action
Indication Contraindication Adverse
Effects
Nursing
Responsibilities
D5 0.3 NaCl
500 cc
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Classification Mechanisms
of Action
Indication Contraindication Adverse
Effects
Nursing
Responsibilities
D5 IMB 500ml