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8/8/2019 Drugs Car La

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Drug Study

Classification Mechanisms

of Action

Indication Contraindication Adverse

Effects

Nursing

Responsibilities

Ampicillin Anti-infective Interferes

with cell wall

synthesis of

susceptible

organism,

preventing

bacterial

multiplication

Deactivated

by beta-

lactamase,an enzyme

produced by

resistant

bacteria.

Treatment of

respiratory

tract and soft

tissue

infection,

bacterial

meningitis,

septicemia

and

gonococal

infections

caused by

susceptible

microorganis

ms

Hypersensitivi

ty to penicillins,

cephalosporins

or imipenem

Oral form not

used to treat

severe

pneumonia,

bacteremia,

pericarditis,

purulent or septicarthritis during

acute stage

Thro

mbophle

bitis at

injection

site

Irritabi

lity

Skin

rashes

Itchy

eyes

Laryn

gospasm

Laryn

geal

edema

Diarrh

ea

Obtain patient

history of infection

before and during

therapy to assess

response

Assess patient for

signs and

symptoms of

infection, fever,

characteristics of

wounds, sputum,urine, stool, ear

ache, and WBC

count

Obtain CNS

before drug

therapy to identify

if correct

treatment has

been initiated

Assess for

allergic or


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hypersensitivity

reactions: chills,

fever, joint pain,

pruritus and rash.

Monitor renal

function: urine

output, urinalysis:

protein and blood.

Assess for over

growth of

infection: perineal

itching, fever,

malaise, redness,

pain, swelling,

drainage, rash,diarrhea, or

change in

character of

cough and

sputum.


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of Action


Effects

Nursing

Responsibilities

Gentamicin Anti-infective Interfere

s with proteinsynthesis inbacterial cellby binding toribosomalsubunit,causingmisreading ofgenetic code;inaccuratepeptidesequenceforms inprotein chain,causingbacterialdeath

Interferes

with proteinsynthesisin bacterialcell bybinding toribosomalsubunit,causingmisreadingof geneticcode;inaccuratepeptidesequenceforms inproteinchain,causingbacterialdeath

Hypersensitivit

y to gentamicinInjury andulceration of thecornea, viralinfection ormycosis

Headache

Fever

Muscleweaknessandtwitching

Acuteorganicbrainsyndrome

Rash

Itching

Anaphylaxis

Apnea

Anemia

Assess

patient forprevioussensitivityreacyion

Assesspatient for signsand symptoms ofinfection

Assess forallergic reaction:rash, chills, fever

Identify urineoutput

Monitor forbleeding

Monitor inputoutput

Assess fordehydration


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of Action


Effects

Nursing

Responsibilities

Vitamin K Clotting

vitamin/agent

Vitamin K

is fat soluble

vitamin that

plays an

important

role in blood

clotting

For those

with

vitamin K

deficiency.

In patients

receiving

anticoagulants as

vitamin K decreas

the effects of the

drugs

Decreased

appetite,

decreases

movement

or activity;

difficult in

breathing,

enlarged

liver,

general

body

swimming,muscle

stiffness,

yellow

eyes or

skin.

Difficulty in

swallowing

; fast or

irregular

breathing;

lightheade

dness or

If you take

warfarin(a blood

thinner, you should

know that vitamin k

or food containing

vitami k can affect

the the drug

Vitamin K

deficiency is very

rare. It occurs when

the cody cantproperl absorb the

vitamihn from the

intestinal tract

Vitamin k deficiency

can also occur after

long term treatment

with antibiotics

If you are taking

anticoagulantmedicines(bloodthi

nners), the amount


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of Action


Effects

Nursing

Responsibilities

Fusidic acid Opthalmic

Prparations

Inhibits

bacterial

photosynthe

sis; it does

not bind to

the bacterial

ribosomes

but inhibits

the factor

necessary

for

translocation of peptide

subunits

and

elongation

of the

peptide

chain;

bacteriostati

c or

bactericidal

Treatm

ent of

staphyloco

ccal

infections,

often in

conjunction

with other

drugs

Hypersensitivi

ty

Hypers

ensitivity

reactions

in the form

of rashes

and

irritation

may occur

after the

topical

administra

tion offusidates;

rash is

rare after

systemic

administra

tion

Obtain

patients history

including

hypersensitivity

Assess the

patient for signs

and symptoms of

infection including

characteristics of

wounds, urine,

stool, ear ache,fever; obtain

baseline

information before

and during

treatment

Perform

periodic

monitoring of liver

function test

Monitor

hypocalcaemia


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of Action


Effects

Nursing

Responsibilities

D5 0.3 NaCl

500 cc


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of Action


Effects

Nursing

Responsibilities

D5 IMB 500ml

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