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Page 1: Dear colleagues and friends,
Page 2: Dear colleagues and friends,
Page 3: Dear colleagues and friends,

Dear colleagues and friends,

Bucharest PancreaticFest is the biggest annual pancreatology academic event in Romania. This new edition of the conference will take place on September 10 and 11 , 2021 at the same place , Crowne Plaza Hotel in Bucharest . In accordance with COVID-19 restrictions worldwide , Bucharest PancreaticFest 2021 will be available virtually for the first time.

The format of this event hasn’t changed: we’ll spend together two days – one dedicated to EUS Workshop in Pancreatic Diseases, and the other to Pancreatic Diseases Course.

The EUS Workshop day will be devoted to video presentations spaced out by state-of-the-art lectures on hot topics on Interventional EUS. Our 2021 guest faculty consists of international renowned endoscopists, already friends of us and almost permanent guests: Peter Vilmann from Copenhagen, Denmark, Erwin Santo from Tel Aviv, Israel Shyam Varadarajulu from Orlando ,US and Radu Tutuian from Berne, Switzerland. At the same time ,video presentations facilitate close educational interactions between experts/faculty and attendants – so, please, take this opportunity to ask and share opinions and experience. The talks scheduled between video demonstrations will focus on practical issues. The theme of the second day – the day dedicated to Pancreatic Diseases Course - is „Standard and cutting-edge issues in pancreatic diseases”. It is devoted to issues in diagnosis and management of common pancreatic diseases: pancreatic cancer, acute and chronic pancreatitis. Peter Hegyi from Szeged - Hungary, a permanent invited speaker and friend of Romanian pancreatologists, will be again with us will give a state of the art conference "The translational medicine cycle model focused on managing acute pancreatitis" . We go further this year with a special session "Original Papers : preliminary results from PhD Thesis"; our fellows will present parts from PhD thesis in pancreatology. We are delighted to provide a FREE registration offer to all the participants To participate in the meeting virtually, please register through the link below: https://pancreaticfest2021.seamless-online.ro/ Acces will only be granted to those who are registered We will do our outmost to make your participation an educational one and also make sure that you will take home some new evidence-based knowledge, tips and tricks in pancreatology.

We look forward to welcoming you virtually at Bucharest PancreaticFest 2021

Cristian Gheorghe

Scientific coordinator of the program

Page 4: Dear colleagues and friends,

Programme Friday, September 10th

08.00 – 08.30 Welcome and introductory remarks Cristian Gheorghe, Mircea Diculescu, Andrada Seicean, Florentina Ioniță-Radu, Marcel Tanțău

9th EUS Workshop for Pancreatic Pathology

Chair: Cristian Gheorghe, Adrian Săftoiu, Mariana Jinga, Radu Țuțuian

08.30 – 09.00 Lecture: Interventional EUS: current status in 2021 Cristian Gheorghe (Romania)

09.00 – 09.40 Video demonstration 1 Peter Vilmann, Erwin Santo, Mariana Jinga

09.40 – 10.00 Lecture: How to organize the EUS service in 2021 for interventional EUS Radu Țuțuian (Switzerland) 10.00 – 10.40Video demonstration 2 Radu Țuțuian, Peter Vilmann, Eugen Dumitru

10.40 – 11.00 Lecture: Current data about LAMS for drainage of pancreatic walled-off necrosis Andrada Seicean (Romania)

11.00 – 11.30 Coffee break

Chair: Adrian Săftoiu, Andrada Seicean, Erwin Santo

11.30 – 12.10Video demonstration 3 Adrian Săftoiu, Peter Vilmann, Lucian Negreanu

12.10 – 12.40 Lecture: The role of EUS-guided biliary drainage in pancreatic diseases Peter Vilmann (Denmark)

12.40 – 13.20Video demonstration 4 Erwin Santo, Adrian Săftoiu

13.20 – 13.50Lecture: Drainage of peripancreatic fluid collections. Is there still a role for percutaneous drainage in 2021? Zeno Spârchez (Romania)

13.50 – 14.40 Lunch

Chair: Marcel Tanțău, Lucian Negreanu, Peter Vilmann

14.40 – 15.20 Video demonstration 5 Andrada Seicean, Erwin Santo, Shyam Varadarajulu

15.20 – 15.40Lecture: Disconnected pancreatic syndrome: endoscopic or surgical intervention? Marcel Tanțău (Romania)

15.40 – 16.00Lecture: EUS-guided pancreatic duct access: indications and limits Shyam Varadarajulu (USA)

16.00 – 16.20 Lecture: EUS-guided gastro-jejunostomy? Peter Vilmann (Denmark), Adrian Săftoiu (Romania)

16.20 – 16.40 Lecture: EUS-guided ablation for pancreatic tumors Erwin Santo (Israel)

16.40 – 17.00Lecture: EUS-related pathology for pancreatic tumors in daily practice Mona Dumbravă, Gabriel Becheanu (Romania)

17.00 – 17.15 Educational session organized by APPR with support from Innergy: Microbiota and pancreatic disease

Page 5: Dear colleagues and friends,

Programme Friday, September 10th

08.00 – 08.30 Welcome and introductory remarks Cristian Gheorghe, Mircea Diculescu, Andrada Seicean, Florentina Ioniță-Radu, Marcel Tanțău

9th EUS Workshop for Pancreatic Pathology

Chair: Cristian Gheorghe, Adrian Săftoiu, Mariana Jinga, Radu Țuțuian

08.30 – 09.00 Lecture: Interventional EUS: current status in 2021 Cristian Gheorghe (Romania)

09.00 – 09.40 Video demonstration 1 Peter Vilmann, Erwin Santo, Mariana Jinga

09.40 – 10.00 Lecture: How to organize the EUS service in 2021 for interventional EUS Radu Țuțuian (Switzerland) 10.00 – 10.40Video demonstration 2 Radu Țuțuian, Peter Vilmann, Eugen Dumitru

10.40 – 11.00 Lecture: Current data about LAMS for drainage of pancreatic walled-off necrosis Andrada Seicean (Romania)

11.00 – 11.30 Coffee break

Chair: Adrian Săftoiu, Andrada Seicean, Erwin Santo

11.30 – 12.10Video demonstration 3 Adrian Săftoiu, Peter Vilmann, Lucian Negreanu

12.10 – 12.40 Lecture: The role of EUS-guided biliary drainage in pancreatic diseases Peter Vilmann (Denmark)

12.40 – 13.20Video demonstration 4 Erwin Santo, Adrian Săftoiu

13.20 – 13.50Lecture: Drainage of peripancreatic fluid collections. Is there still a role for percutaneous drainage in 2021? Zeno Spârchez (Romania)

13.50 – 14.40 Lunch

Chair: Marcel Tanțău, Lucian Negreanu, Peter Vilmann

14.40 – 15.20 Video demonstration 5 Andrada Seicean, Erwin Santo, Shyam Varadarajulu

15.20 – 15.40Lecture: Disconnected pancreatic syndrome: endoscopic or surgical intervention? Marcel Tanțău (Romania)

15.40 – 16.00Lecture: EUS-guided pancreatic duct access: indications and limits Shyam Varadarajulu (USA)

16.00 – 16.20 Lecture: EUS-guided gastro-jejunostomy? Peter Vilmann (Denmark), Adrian Săftoiu (Romania)

16.20 – 16.40 Lecture: EUS-guided ablation for pancreatic tumors Erwin Santo (Israel)

16.40 – 17.00Lecture: EUS-related pathology for pancreatic tumors in daily practice Mona Dumbravă, Gabriel Becheanu (Romania)

17.00 – 17.15 Educational session organized by APPR with support from Innergy: Microbiota and pancreatic disease

Page 6: Dear colleagues and friends,

Saturday, September 11th 8th Pancreatic Disease Course

08.15 – 08.45 Pancreatology literature update: Cristian Gheorghe Cristian Gheorghe (Romania)

08.45 – 09.15 State of the art lecture: Effects of COVID-19 pandemic on the management of pancreatic diseases Cristina Cijevschi (Romania)

09.15 – 09.45 State of the art lecture: The translational medicine cycle model focused on managing acute pancreatitis Peter Hegyi (Hungary)

Session 1: Severe acute pancreatitis Chair: Gabriel Constantinescu, Vlad Constantin, Ioana Grințescu

09.55 – 10.15 What means "severe acute pancreatitis"? Vasile Drug, Andrei Oltean, Lidia Ionescu (Romania)

10.15 – 10.35 Intravenous fluid resuscitation and nutritional support in patients with severe acute pancreatitis: Current standards Ioana Grintescu, Ana Cotae (Romania)

10.35 – 10.55 An appropriate time for ERCP and cholecystectomy in biliary pancreatitis Eugen Dumitru (Romania)

10.55 – 11.15 The role of surgery in multidisciplinary collaboration for acute necrotizing pancreatitis Vlad Constantin, Bogdan Socea (Romania)

11.15 – 11.30 The advanced endoscopic management of complications associated with pancreatectomy Cristian Rosianu, Madalina Florescu, Daniela Tabacelia, Cezar Stroescu (Romania)

11.30 – 11.45 Coffee break

Session 2: Pancreatic tumors Chair: Irinel Popescu, Adina Croitoru, Ioana Lupescu, Mariana Jinga

11.45 – 12.05Current status of artificial intelligence analysis for EUS diagnosis of PDAC Adrian Săftoiu (Romania)

12.05 – 12.25Importance of multiplanar and MIP reconstructions in the management of PDAC Gina Rusu, Mugur Grasu, Ioana Lupescu (Romania)

12.25 – 12.45Neoadjuvant chemotherapy for borderline PDAC: which is the most effective regimen in 2021? Adina Croitoru (Romania)

12.45 – 13.05Can imaging offer an accurate local evaluation after neoadjuvant treatment of borderline pancreatic tumors? Mugur Grasu, Gina Rusu, Ioana Lupescu (Romania)

13.05 – 13.25Technical advances in surgery for borderline PDAC after neoadjuvant therapy Irinel Popescu, Simona Dima, Traian Dumitrascu, Nicolae Bacalbasa (Romania)

13.25 – 13.45Metal vs plastic stent for borderline PDAC of the head of the pancreas before neoadjuvant chemotherapy Ion Băncilă, Cristian Gheorghe (Romania)

13.45 – 14.05

Genomic profile of resectable pancreatic ductal adenocarcinoma assessed by whole exome sequencing of microdisected tumoral tissue PANCNGS Research Group. Presenting authors: Simona Dima and Razvan Iacob

Page 7: Dear colleagues and friends,

Saturday, September 11th 8th Pancreatic Disease Course

08.15 – 08.45 Pancreatology literature update: Cristian Gheorghe Cristian Gheorghe (Romania)

08.45 – 09.15 State of the art lecture: Effects of COVID-19 pandemic on the management of pancreatic diseases Cristina Cijevschi (Romania)

09.15 – 09.45 State of the art lecture: The translational medicine cycle model focused on managing acute pancreatitis Peter Hegyi (Hungary)

Session 1: Severe acute pancreatitis Chair: Gabriel Constantinescu, Vlad Constantin, Ioana Grințescu

09.55 – 10.15 What means "severe acute pancreatitis"? Vasile Drug, Andrei Oltean, Lidia Ionescu (Romania)

10.15 – 10.35 Intravenous fluid resuscitation and nutritional support in patients with severe acute pancreatitis: Current standards Ioana Grintescu, Ana Cotae (Romania)

10.35 – 10.55 An appropriate time for ERCP and cholecystectomy in biliary pancreatitis Eugen Dumitru (Romania)

10.55 – 11.15 The role of surgery in multidisciplinary collaboration for acute necrotizing pancreatitis Vlad Constantin, Bogdan Socea (Romania)

11.15 – 11.30 The advanced endoscopic management of complications associated with pancreatectomy Cristian Rosianu, Madalina Florescu, Daniela Tabacelia, Cezar Stroescu (Romania)

11.30 – 11.45 Coffee break

Session 2: Pancreatic tumors Chair: Irinel Popescu, Adina Croitoru, Ioana Lupescu, Mariana Jinga

11.45 – 12.05Current status of artificial intelligence analysis for EUS diagnosis of PDAC Adrian Săftoiu (Romania)

12.05 – 12.25Importance of multiplanar and MIP reconstructions in the management of PDAC Gina Rusu, Mugur Grasu, Ioana Lupescu (Romania)

12.25 – 12.45Neoadjuvant chemotherapy for borderline PDAC: which is the most effective regimen in 2021? Adina Croitoru (Romania)

12.45 – 13.05Can imaging offer an accurate local evaluation after neoadjuvant treatment of borderline pancreatic tumors? Mugur Grasu, Gina Rusu, Ioana Lupescu (Romania)

13.05 – 13.25Technical advances in surgery for borderline PDAC after neoadjuvant therapy Irinel Popescu, Simona Dima, Traian Dumitrascu, Nicolae Bacalbasa (Romania)

13.25 – 13.45Metal vs plastic stent for borderline PDAC of the head of the pancreas before neoadjuvant chemotherapy Ion Băncilă, Cristian Gheorghe (Romania)

13.45 – 14.05

Genomic profile of resectable pancreatic ductal adenocarcinoma assessed by whole exome sequencing of microdisected tumoral tissue PANCNGS Research Group. Presenting authors: Simona Dima and Razvan Iacob

Page 8: Dear colleagues and friends,

14.05 – 14.25Advances in the management of pancreatic cystic neoplasms Mariana Jinga, Vasile Balaban (Romania)

14.25 – 14.45Robotic pancreatico-duodenectomy: next level for pancreatic minimal invasive surgery Cătălin Copăescu (Romania)

14.45 – 15.00Educational session organized by APPR with support from VIATRIS: The Benefit of PERT in Neoplastic & Non-neoplastic Pancreatic Diseases

15.00 – 15.30 Lunch

Session 3: Chronic pancreatitis Chair: Liana Gheorghe, Mugur Grasu, Eugen Dumitru, Vasile Drug

15.30 – 15.50What is essential to report in CT and MRI evaluation of chronic pancreatitis? Ioana Lupescu, Gina Rusu, Mugur Grasu

15.50 – 16.10Diagnostic and therapy of chronic pancreatitis according to UEG guidelines Anda Les, Cristian Gheorghe

16.10 – 16.30 Nutrition management of chronic pancreatitis Liana Gheorghe (Romania)

16.30 – 16.50Pancreatic pseudocyst: endoscopy or surgery drainage? Mihai Ciocîrlan (Romania)

Session 4: Original Papers: preliminary results from PhD Thesis Chair: Razvan Iacob, Simona Dima, Andrada Seicean, Adrian Saftoiu

16.50 – 17.05Molecular characterization of PDAC using ccfDNA liquid biopsy Bianca Stoica, Stefania Bunduc, R. Iacob, A. Sorop, Ioana Manea, Diana Constantinescu, Elena Moise, Maria Sirbu, Ana Maria

Pantazica, Alina Ghionescu, Raluca Chelaru, G. Becheanu, Mona Dumbrava, Adina Croitoru, Simona Dima, I. Popescu, C. Gheorghe

17.05 – 17.20

Somatic mutations in pancreatic adenocarcinoma diagnosed by EUS-FNA - correlations with cell-free DNA Stefania Bunduc, Bianca Stoica, R. Iacob, A. Sorop, Ioana Manea, Diana Constantinescu, Elena Moise, Maria Sirbu, Ana Maria Pantazica, Alina Ghionescu, Raluca Chelaru, G. Becheanu, Mona Dumbrava, Adina Croitoru, Simona Dima, I. Popescu, C. Gheorghe

17.20 – 17.35Obesity and pancreatic cancer Raluca Grigorescu, Cristina Radu, Madalina Florescu, Husar Sburlan Ioana, Daniela Tabacelia, Ioana Stanel, Adina Croitoru, Cristian Gheorghe

17.35 – 17.50Differentiation of pancreatic cysts by contrast-enhanced EUS Miruna Patricia Olar, Ofelia Mosteanu, Ioana Rusu, Radu Badea, Sorana Bolboaca, Andrada Seicean

17.50 – 18.05 EUS characteristics in neuroendocrine tumours Ionuț Saizu, Cristian Gheorghe

18.05 – 18.20Etiology and clinical features in recurrent acute pancreatitis: Experience from a single center Cristina Patoni, Vasile Balaban, Mariana Jinga, Cristian Gheorghe

18.20 – 18.35

Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients with Pancreatic Cancer Alina Constantin, Vlad Iovănescu, Irina Mihaela Cazacu, Oana Plotogea, Cătălin Copăescu, Nona Bejinariu, Adrian Săftoiu

18.35 – 19.00 Discussion

19.00 Wrap-up

Page 9: Dear colleagues and friends,

14.05 – 14.25Advances in the management of pancreatic cystic neoplasms Mariana Jinga, Vasile Balaban (Romania)

14.25 – 14.45Robotic pancreatico-duodenectomy: next level for pancreatic minimal invasive surgery Cătălin Copăescu (Romania)

14.45 – 15.00Educational session organized by APPR with support from VIATRIS: The Benefit of PERT in Neoplastic & Non-neoplastic Pancreatic Diseases

15.00 – 15.30 Lunch

Session 3: Chronic pancreatitis Chair: Liana Gheorghe, Mugur Grasu, Eugen Dumitru, Vasile Drug

15.30 – 15.50What is essential to report in CT and MRI evaluation of chronic pancreatitis? Ioana Lupescu, Gina Rusu, Mugur Grasu

15.50 – 16.10Diagnostic and therapy of chronic pancreatitis according to UEG guidelines Anda Les, Cristian Gheorghe

16.10 – 16.30 Nutrition management of chronic pancreatitis Liana Gheorghe (Romania)

16.30 – 16.50Pancreatic pseudocyst: endoscopy or surgery drainage? Mihai Ciocîrlan (Romania)

Session 4: Original Papers: preliminary results from PhD Thesis Chair: Razvan Iacob, Simona Dima, Andrada Seicean, Adrian Saftoiu

16.50 – 17.05Molecular characterization of PDAC using ccfDNA liquid biopsy Bianca Stoica, Stefania Bunduc, R. Iacob, A. Sorop, Ioana Manea, Diana Constantinescu, Elena Moise, Maria Sirbu, Ana Maria

Pantazica, Alina Ghionescu, Raluca Chelaru, G. Becheanu, Mona Dumbrava, Adina Croitoru, Simona Dima, I. Popescu, C. Gheorghe

17.05 – 17.20

Somatic mutations in pancreatic adenocarcinoma diagnosed by EUS-FNA - correlations with cell-free DNA Stefania Bunduc, Bianca Stoica, R. Iacob, A. Sorop, Ioana Manea, Diana Constantinescu, Elena Moise, Maria Sirbu, Ana Maria Pantazica, Alina Ghionescu, Raluca Chelaru, G. Becheanu, Mona Dumbrava, Adina Croitoru, Simona Dima, I. Popescu, C. Gheorghe

17.20 – 17.35Obesity and pancreatic cancer Raluca Grigorescu, Cristina Radu, Madalina Florescu, Husar Sburlan Ioana, Daniela Tabacelia, Ioana Stanel, Adina Croitoru, Cristian Gheorghe

17.35 – 17.50Differentiation of pancreatic cysts by contrast-enhanced EUS Miruna Patricia Olar, Ofelia Mosteanu, Ioana Rusu, Radu Badea, Sorana Bolboaca, Andrada Seicean

17.50 – 18.05 EUS characteristics in neuroendocrine tumours Ionuț Saizu, Cristian Gheorghe

18.05 – 18.20Etiology and clinical features in recurrent acute pancreatitis: Experience from a single center Cristina Patoni, Vasile Balaban, Mariana Jinga, Cristian Gheorghe

18.20 – 18.35

Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients with Pancreatic Cancer Alina Constantin, Vlad Iovănescu, Irina Mihaela Cazacu, Oana Plotogea, Cătălin Copăescu, Nona Bejinariu, Adrian Săftoiu

18.35 – 19.00 Discussion

19.00 Wrap-up

Page 10: Dear colleagues and friends,
Page 11: Dear colleagues and friends,
Page 12: Dear colleagues and friends,