Bimonthly Meeting on Jan. 23, 2009Chemical Information on Phantom by Gaussian FunctionAmarjeet Bhullar

7*7=49 VoxelsCho=3097.32Cre=3726.94NAA=4818.51

Voxel 1 to 49GaussianCho/Cre0.831Cho/NAA0.642

15*15=225 VoxelsCho=8497.17Cre=10162.30NAA=13166.20

Voxel 1 to 225GaussianCho/Cre0.836Cho/NAA0.645

7*7=49 Voxels and 15*15=225 Voxels

Comparison between 7*7 and 15*15 Spectra

Voxel 1 to 49GaussianCho/Cre0.831Cho/NAA0.642

Voxel 1 to 225GaussianCho/Cre0.836Cho/NAA0.645

Metabolite peaks fit by Gaussian function

Cho=26.4059Cre=38.3233NAA=50.3961Calculation of Metabolite Concentrations

Cho=30.047Cre=45.8772NAA=51.899Calculation of Metabolite Concentrations

Cho=27.7975Cre=39.7157NAA=50.4718Calculation of Metabolite Concentrations

Cho=34.0246Cre=49.0628NAA=60.5868Calculation of Metabolite Concentrations

Cho=123.506Cre=174.144NAA=220.372Calculation of Metabolite Concentrations

Cho=67.1154Cre=74.2094NAA=93.7448Calculation of Metabolite Concentrations

Voxel Comparison

15*15ChoCreNAAVox#3326.405938.323350.3961Vox#3430.047045.877251.8990Vox#4827.797539.715750.4718Vox#4934.024649.062860.5869Total Con.110.6558172.979213.3538

15*15ChoCreNAAVox#33+34+48+49123.506174.144220.372

7*7ChoCreNAAVox#967.115474.209493.7448

Conclusion:Even difference of smallest fraction between voxel size (7*7 and 15*15) creates differentmetabolite concentrations.Suggestions are welcome

Row Wise Distribution of Cho/Cre

Row Wise Distribution of Cho/NAA

Metabolite Ratios by Gaussian function

Voxel #1GaussianCho/Cre0.751014Cho/NAA0.82592

Voxel #2GaussianCho/Cre0.920288Cho/NAA1.204818

Voxel #3GaussianCho/Cre1.026504Cho/NAA1.00366

Voxel #4GaussianCho/Cre0.934274Cho/NAA1.265779

Metabolite Ratios by Gaussian function

Voxel #4GaussianCho/Cre0.934274Cho/NAA1.265779

Voxel #5GaussianCho/Cre0.913693Cho/NAA0.950665

Voxel #6GaussianCho/Cre0.905497Cho/NAA1.00024

Voxel #7GaussianCho/Cre0.890625Cho/NAA1.284948

Metabolite Ratios by Gaussian function

Voxel #8GaussianCho/Cre0.860931Cho/NAA0.544306

Voxel #9GaussianCho/Cre0.904406Cho/NAA0.715937

Voxel #10GaussianCho/Cre0.817914Cho/NAA0.667594

Voxel #11GaussianCho/Cre0.836532Cho/NAA0.680032

Metabolite Ratios by Gaussian function

Voxel #12GaussianCho/Cre0.859035Cho/NAA0.683185

Voxel #13GaussianCho/Cre0.84962Cho/NAA0.697155

Voxel #14GaussianCho/Cre0.770389Cho/NAA0.74367

Voxel #15GaussianCho/Cre0.915505Cho/NAA0.559509

Metabolite Ratios by Gaussian function

Voxel #16GaussianCho/Cre0.89351Cho/NAA0.650015

Voxel #17GaussianCho/Cre0.807657Cho/NAA0.605227

Voxel #18GaussianCho/Cre0.807195Cho/NAA0.619962

Voxel #19GaussianCho/Cre0.839769Cho/NAA0.611889

Metabolite Ratios by Gaussian function

Voxel #20GaussianCho/Cre0.815158Cho/NAA0.617085

Voxel #21GaussianCho/Cre0.691482Cho/NAA0.592537

Voxel #22GaussianCho/Cre0.808174Cho/NAA0.48208

Voxel #23GaussianCho/Cre0.842664Cho/NAA0.615965

Metabolite Ratios by Gaussian function

Voxel #24GaussianCho/Cre0.80954Cho/NAA0.616462

Voxel #25GaussianCho/Cre0.824471Cho/NAA0.620819

Voxel #26GaussianCho/Cre0.812873Cho/NAA0.593714

Voxel #27GaussianCho/Cre0.764973Cho/NAA0.614783

Metabolite Ratios by Gaussian function

Voxel #28GaussianCho/Cre0.693088Cho/NAA0-643046

Voxel #29GaussianCho/Cre0.820805Cho/NAA0.541781

Voxel #30GaussianCho/Cre0.863645Cho/NAA0.615628

Voxel #31GaussianCho/Cre0.822132Cho/NAA0.615398

Metabolite Ratios by Gaussian function

Voxel #32GaussianCho/Cre0.863442Cho/NAA0.64706

Voxel #33GaussianCho/Cre0.829424Cho/NAA0.630388

Voxel #34GaussianCho/Cre0.826255Cho/NAA0.64566

Voxel #35GaussianCho/Cre0.838811Cho/NAA0.755696

Metabolite Ratios by Gaussian function

Voxel #36GaussianCho/Cre0.813257Cho/NAA0.524243

Voxel #37GaussianCho/Cre0.883596Cho/NAA0.565531

Voxel #38GaussianCho/Cre0.895173Cho/NAA0.661893

Voxel #39GaussianCho/Cre0.915392Cho/NAA0.724875

Metabolite Ratios by Gaussian function

Voxel #40GaussianCho/Cre0.933848Cho/NAA0.707293

Voxel #41GaussianCho/Cre0.877934Cho/NAA0.739058

Voxel #42GaussianCho/Cre0.89324Cho/NAA0.83322

Voxel #43GaussianCho/Cre0.620034Cho/NAA0.399859

Metabolite Ratios by Gaussian function

Voxel #44GaussianCho/Cre0.77063Cho/NAA0.522992

Voxel #45GaussianCho/Cre0.77063Cho/NAA0.529867

Voxel #46GaussianCho/Cre0.92655Cho/NAA0.663082

Voxel #47GaussianCho/Cre0.903481Cho/NAA0.627585

Metabolite Ratios by Gaussian function

Voxel #48GaussianCho/Cre0.879797Cho/NAA0.644314

Voxel #49GaussianCho/Cre0.659546Cho/NAA0.601717

Conclusion:All the data reveals that the Gaussian Function is the best fit for MagneticResonance Spectroscopy.Suggestions are welcome