salmonella - umcms.um.edu.my · s.thypi and s. paratyhpi a with an internal control • detect and...

SALMONELLA

Our Solu�on & Technology

Lee Ching ShyaUMCIC Business Officer

University of Malaya Email: leecs@um.edu.myTel: +603-7967-7351/7352

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ProblemApplica�ons

Advantages

To reduce serious complica�ons,mortality and carriage state

This PCR kit can detect and differen�ate the agents in 3 hoursas compared to 3-5 days using the conven�onal methods. Theinclusion of internal amplifica�on control can avoid falsenega�ve and produce more reliable results. The test is easy toperform in any laboratory equipped with a thermocycler andsimple electrophore�c facility. This PCR kit can be used todetect pathogens in clinical, food and environmental samples.This kit is useful for quick and early detec�on oftyphoid/paratyphoid fever and the source of poten�aloutbreak. It can also be used for carrier screening among foodhandlers. In the absence of serotyping facili�es, iden�fica�onof Salmonella Typhi and Paratyphi A is possible with this PCRkit.

Typhoid and paratyphoid fevers caused by Salmonella Typhiand Paratyphi A continue to pose significant public healthproblems in many parts of the world. Clinical diagnosis oftyphoid and paratyphoid fever is difficult because the signs andsymptoms are not unique and overlap with other commonfebrile illness. Rapid and sensitive laboratory methods areessential for prompt and effective therapy – to reduce seriouscomplications, mortality and carriage state. We have patentedspecific oligonucleotides to detect these bacteria anddeveloped a simple and rapid PCR assay.

• UMCIC File Number: 628/350• Patent Number: MY-151978-A• Patent Status: Patent Granted• Malaysia Patent: One Step

Mul�plex System for the Detec�onof Salmonella Spp,. S.Thypi and S.Paratyhpi A With An InternalControl

• Detect and differen�ate the agentsin 3 hours

• Avoid false nega�ve• Produce more reliable results.• The test is easy to perform in any

laboratory.