modelling hip fracture considering intersubject variability in shape and intensity

MO

Introdu

Patient-sp

bone qua

and type

have ch

femoral s

applied to

subjects

2009]. W

minimum

identify r

study init

extended

(Simulia,

Accordin

predict h

statistical

geometry

Method

A series

modes of

shape and

variability

increase

character

reduction

increases

in neck-

reproduce

fall back

Fracture

which ap

determine

path of c

strength

GIC, was

constant G

Result

Fracture

were eva

shape and

scaling M

correlated

perturbati

at fractu

smaller b

bone in th

range o

ODELLIN

Azhar Ali (

1. Computa2. Co

3. Bioengi

uction

pecific factor

ality, are know

of fracture.

haracterized

shape and inte

o evaluate bo

for a simul

While prior m

m and maxi

regions of hi

tiated and pro

finite elemen

Providenc

ngly, the obje

hip fracture

l model-gene

y and bone qua

ds

of models rep

f variation we

d intensity m

y, Mode 1 r

in anteversi

rized thicken

ns in highes

in medullary

shaft angle.

ed an experi

kwards and t

was modelle

pplies stress

e the location

crack propaga

[Morgan, 200

a function of

GIC/GIIC ratio

s

patterns and

luated in mod

d density of th

Mode 1, app

d to femora

ions in Mode

ure, but due

bone volume in

he other (+2�

f experimen

NG HIP FVARIAB

1), Brian Bu

ational Biomlorado Joinineering Sc

rs, including

wn to influenc

Recently, st

intersubject

ensity [Bryan,

one strains in

lated fall con

modelling eff

imum princi

igh fracture r

opagated crac

nt method (XF

ce, RI)

ective of this

behaviour i

erated subject

ality.

presenting the

ere created fro

model. Captur

represented s

ion angle.

ning of th

t modulus (

y cavity volum

The bound

ment simulat

to the side

ed with XFE

and energy-b

n of crack in

tion. Similar

01], the ener

f density [Coo

[Zimmerman

load at the o

dels represent

he population

plied load a

al size (Fig

2 resulted in

e to differen

n one (-2�) an

�). Fracture lo

ntal values

FRACTURBILITY IN

urks (1), Ray

mechanics Lt Replacem

cience Rese

g anatomy a

ce the likeliho

tatistical mode

variability

2010] and be

a population

ndition [Brya

forts have us

ipal strains

risk, the curre

cks utilizing t

FEM) in Abaq

[Liu, 201

s study was

in a series

ts with varyi

e most comm

om the statistic

ring 45% of t

scaling with

Mode 2 (8%

he bone w

(cortical) bon

me and decreas

dary conditio

ting an obliq

[Keyak, 200

EM in Abaqu

based criteria

nitiation and t

to modulus a

gy release ra

ok, 2010] with

n, 2009].

onset of fractu

ing the range

n. In the large

at fracture w

gure 1). Bo

decreased loa

nt mechanism

nd lower dens

oads were in t

[Keyak, 200

RE CONSSHAPE

ymond Kim

Lab, Univerment, Porter earch Group

and

ood

els

in

een

of

an,

sed

to

ent

the

qus

0].

to

of

ing

mon

cal

the

an

%)

with

ne,

ses

ons

que

0].

us,

to

the

and

ate,

h a

ure

of

ely

was

oth

ads

ms:

sity

the

00]

(F

w

se

D

A

m

fu

lo

co

ca

th

ro

Fi

m

Fi

fo

A

Th

O

R

B

et

M

B

C

56

30

SIDERINAND INT

(1,2), Mark T

rsity of Denvr Hospital, Dp, University

Figure 1). Wh

were observed

ensitive to nec

Discussion

As a complem

modelling crac

urther insight

oad at fractu

ombination o

an identify sh

hat are most s

obustness of re

igure 1: Load

modes of variat

igure 2: Crac

or first two mo

Acknowled

his study w

Osteosynthesis

References

ryan et al, M

t al, J Biomec

Med Eng Ph

iomech, 33:4

onference, 20

69-577, 2001

0:5877-5884,

NG INTERTENSITY

Taylor (3), P

ver, DenverDenver, CO,y of Southam

hile intertrocha

in all models

ck-shaft angle

n

ment to strain

ck initiation

into hip fra

re onset and

f fracture an

hape and bone

usceptible to

epair in the fra

d at onset of fra

tion compared

ck location in

odes of shape a

dgement

was support

and Trauma C

s

ed Eng Phys,

ch, 42:2171-2

hys, 32:991-9

499-502, 200

010. Morgan

. Zimmerman

2009.

RSUBJECY

Peter Laz (1)

r, CO, USA, USA; mpton, UK

anteric fractur

s, fracture loc

(Figure 2).

n and risk ev

and growth

acture, specif

d fracture pa

nd statistical

e quality char

fracture and

actured femur

racture for firs

d to Keyak [20

XFEM fractu

and density va

ted in part

Care Foundati

32:57-65, 20

2176, 2009. C

997, 2010.

00. Liu et

et al, J Biom

nn et al, Bio

CT

)

;

re patterns

cation was

valuations,

provides

fically the

ath. The

modelling

racteristics

assess the

rs.

st two

000].

ure models

ariation.

by the

ion.

010. Bryan

Cook et al,

Keyak, J

al, ASB

mech, 34:

omaterials,

Presentation 1691 − Topic 23. Hip biomechanics S287

ESB2012: 18th Congress of the European Society of Biomechanics Journal of Biomechanics 45(S1)