modelling hip fracture considering intersubject variability in shape and intensity

1
MO Introdu Patient-sp bone qua and type have ch femoral s applied to subjects 2009]. W minimum identify r study init extended (Simulia, Accordin predict h statistical geometry Method A series modes of shape and variability increase character reduction increases in neck- reproduce fall back Fracture which ap determine path of c strength G IC , was constant G Result Fracture were eva shape and scaling M correlated perturbati at fractu smaller b bone in th range o ODELLIN Azhar Ali ( 1. Computa 2. Co 3. Bioengi uction pecific factor ality, are know of fracture. haracterized shape and inte o evaluate bo for a simul While prior m m and maxi regions of hi tiated and pro finite elemen Providenc ngly, the obje hip fracture l model-gene y and bone qua ds of models rep f variation we d intensity m y, Mode 1 r in anteversi rized thicken ns in highes in medullary shaft angle. ed an experi kwards and t was modelle pplies stress e the location crack propaga [Morgan, 200 a function of G IC /G IIC ratio s patterns and luated in mod d density of th Mode 1, app d to femora ions in Mode ure, but due bone volume in he other (+2 f experimen NG HIP F VARIAB 1), Brian Bu ational Biom lorado Join ineering Sc rs, including wn to influenc Recently, st intersubject ensity [Bryan, one strains in lated fall con modelling eff imum princi igh fracture r opagated crac nt method (XF ce, RI) ective of this behaviour i erated subject ality. presenting the ere created fro model. Captur represented s ion angle. ning of th t modulus ( y cavity volum The bound ment simulat to the side ed with XFE and energy-b n of crack in tion. Similar 01], the ener f density [Coo [Zimmerman load at the o dels represent he population plied load a al size (Fig 2 resulted in e to differen n one (-2) an ). Fracture lo ntal values FRACTUR BILITY IN urks (1), Ray mechanics L t Replacem ience Rese g anatomy a ce the likeliho tatistical mode variability 2010] and be a population ndition [Brya forts have us ipal strains risk, the curre cks utilizing t FEM) in Abaq [Liu, 201 s study was in a series ts with varyi e most comm om the statistic ring 45% of t scaling with Mode 2 (8% he bone w (cortical) bon me and decreas dary conditio ting an obliq [Keyak, 200 EM in Abaqu based criteria nitiation and t to modulus a gy release ra ok, 2010] with n, 2009]. onset of fractu ing the range n. In the large at fracture w gure 1). Bo decreased loa nt mechanism nd lower dens oads were in t [Keyak, 200 RE CONS SHAPE ymond Kim Lab, Univer ment, Porter earch Group and ood els in een of an, sed to ent the qus 0]. to of ing mon cal the an %) with ne, ses ons que 0]. us, to the and ate, h a ure of ely was oth ads ms: sity the 00] (F w se D A m fu lo co ca th ro Fi m Fi fo A Th O R B et M B C 56 30 SIDERIN AND INT (1,2), Mark T rsity of Denv Hospital, D p, University Figure 1). Wh were observed ensitive to nec Discussion As a complem modelling crac urther insight oad at fractu ombination o an identify sh hat are most s obustness of re igure 1: Load modes of variat igure 2: Crac or first two mo Acknowled his study w Osteosynthesis References ryan et al, M t al, J Biomec Med Eng Ph iomech, 33:4 onference, 20 69-577, 2001 0:5877-5884, NG INTER TENSITY Taylor (3), P ver, Denver Denver, CO, y of Southam hile intertrocha in all models ck-shaft angle n ment to strain ck initiation into hip fra re onset and f fracture an hape and bone usceptible to epair in the fra d at onset of fra tion compared ck location in odes of shape a dgement was support and Trauma C s ed Eng Phys, ch, 42:2171-2 hys, 32:991-9 499-502, 200 010. Morgan . Zimmerman 2009. RSUBJEC Y Peter Laz (1) r, CO, USA , USA; mpton, UK anteric fractur s, fracture loc (Figure 2). n and risk ev and growth acture, specif d fracture pa nd statistical e quality char fracture and actured femur racture for firs d to Keyak [20 XFEM fractu and density va ted in part Care Foundati 32:57-65, 20 2176, 2009. C 997, 2010. 00. Liu et et al, J Biom nn et al, Bio CT ) ; re patterns cation was valuations, provides fically the ath. The modelling racteristics assess the rs. st two 000]. ure models ariation. by the ion. 010. Bryan Cook et al, Keyak, J al, ASB mech, 34: omaterials, Presentation 1691 − Topic 23. Hip biomechanics S287 ESB2012: 18th Congress of the European Society of Biomechanics Journal of Biomechanics 45(S1)

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MO

Introdu

Patient-sp

bone qua

and type

have ch

femoral s

applied to

subjects

2009]. W

minimum

identify r

study init

extended

(Simulia,

Accordin

predict h

statistical

geometry

Method

A series

modes of

shape and

variability

increase

character

reduction

increases

in neck-

reproduce

fall back

Fracture

which ap

determine

path of c

strength

GIC, was

constant G

Result

Fracture

were eva

shape and

scaling M

correlated

perturbati

at fractu

smaller b

bone in th

range o

ODELLIN

Azhar Ali (

1. Computa2. Co

3. Bioengi

uction

pecific factor

ality, are know

of fracture.

haracterized

shape and inte

o evaluate bo

for a simul

While prior m

m and maxi

regions of hi

tiated and pro

finite elemen

Providenc

ngly, the obje

hip fracture

l model-gene

y and bone qua

ds

of models rep

f variation we

d intensity m

y, Mode 1 r

in anteversi

rized thicken

ns in highes

in medullary

shaft angle.

ed an experi

kwards and t

was modelle

pplies stress

e the location

crack propaga

[Morgan, 200

a function of

GIC/GIIC ratio

s

patterns and

luated in mod

d density of th

Mode 1, app

d to femora

ions in Mode

ure, but due

bone volume in

he other (+2�

f experimen

NG HIP FVARIAB

1), Brian Bu

ational Biomlorado Joinineering Sc

rs, including

wn to influenc

Recently, st

intersubject

ensity [Bryan,

one strains in

lated fall con

modelling eff

imum princi

igh fracture r

opagated crac

nt method (XF

ce, RI)

ective of this

behaviour i

erated subject

ality.

presenting the

ere created fro

model. Captur

represented s

ion angle.

ning of th

t modulus (

y cavity volum

The bound

ment simulat

to the side

ed with XFE

and energy-b

n of crack in

tion. Similar

01], the ener

f density [Coo

[Zimmerman

load at the o

dels represent

he population

plied load a

al size (Fig

2 resulted in

e to differen

n one (-2�) an

�). Fracture lo

ntal values

FRACTURBILITY IN

urks (1), Ray

mechanics Lt Replacem

cience Rese

g anatomy a

ce the likeliho

tatistical mode

variability

2010] and be

a population

ndition [Brya

forts have us

ipal strains

risk, the curre

cks utilizing t

FEM) in Abaq

[Liu, 201

s study was

in a series

ts with varyi

e most comm

om the statistic

ring 45% of t

scaling with

Mode 2 (8%

he bone w

(cortical) bon

me and decreas

dary conditio

ting an obliq

[Keyak, 200

EM in Abaqu

based criteria

nitiation and t

to modulus a

gy release ra

ok, 2010] with

n, 2009].

onset of fractu

ing the range

n. In the large

at fracture w

gure 1). Bo

decreased loa

nt mechanism

nd lower dens

oads were in t

[Keyak, 200

RE CONSSHAPE

ymond Kim

Lab, Univerment, Porter earch Group

and

ood

els

in

een

of

an,

sed

to

ent

the

qus

0].

to

of

ing

mon

cal

the

an

%)

with

ne,

ses

ons

que

0].

us,

to

the

and

ate,

h a

ure

of

ely

was

oth

ads

ms:

sity

the

00]

(F

w

se

D

A

m

fu

lo

co

ca

th

ro

Fi

m

Fi

fo

A

Th

O

R

B

et

M

B

C

56

30

SIDERINAND INT

(1,2), Mark T

rsity of Denvr Hospital, Dp, University

Figure 1). Wh

were observed

ensitive to nec

Discussion

As a complem

modelling crac

urther insight

oad at fractu

ombination o

an identify sh

hat are most s

obustness of re

igure 1: Load

modes of variat

igure 2: Crac

or first two mo

Acknowled

his study w

Osteosynthesis

References

ryan et al, M

t al, J Biomec

Med Eng Ph

iomech, 33:4

onference, 20

69-577, 2001

0:5877-5884,

NG INTERTENSITY

Taylor (3), P

ver, DenverDenver, CO,y of Southam

hile intertrocha

in all models

ck-shaft angle

n

ment to strain

ck initiation

into hip fra

re onset and

f fracture an

hape and bone

usceptible to

epair in the fra

d at onset of fra

tion compared

ck location in

odes of shape a

dgement

was support

and Trauma C

s

ed Eng Phys,

ch, 42:2171-2

hys, 32:991-9

499-502, 200

010. Morgan

. Zimmerman

2009.

RSUBJECY

Peter Laz (1)

r, CO, USA, USA; mpton, UK

anteric fractur

s, fracture loc

(Figure 2).

n and risk ev

and growth

acture, specif

d fracture pa

nd statistical

e quality char

fracture and

actured femur

racture for firs

d to Keyak [20

XFEM fractu

and density va

ted in part

Care Foundati

32:57-65, 20

2176, 2009. C

997, 2010.

00. Liu et

et al, J Biom

nn et al, Bio

CT

)

;

re patterns

cation was

valuations,

provides

fically the

ath. The

modelling

racteristics

assess the

rs.

st two

000].

ure models

ariation.

by the

ion.

010. Bryan

Cook et al,

Keyak, J

al, ASB

mech, 34:

omaterials,

Presentation 1691 − Topic 23. Hip biomechanics S287

ESB2012: 18th Congress of the European Society of Biomechanics Journal of Biomechanics 45(S1)