modelling hip fracture considering intersubject variability in shape and intensity
TRANSCRIPT
MO
Introdu
Patient-sp
bone qua
and type
have ch
femoral s
applied to
subjects
2009]. W
minimum
identify r
study init
extended
(Simulia,
Accordin
predict h
statistical
geometry
Method
A series
modes of
shape and
variability
increase
character
reduction
increases
in neck-
reproduce
fall back
Fracture
which ap
determine
path of c
strength
GIC, was
constant G
Result
Fracture
were eva
shape and
scaling M
correlated
perturbati
at fractu
smaller b
bone in th
range o
ODELLIN
Azhar Ali (
1. Computa2. Co
3. Bioengi
uction
pecific factor
ality, are know
of fracture.
haracterized
shape and inte
o evaluate bo
for a simul
While prior m
m and maxi
regions of hi
tiated and pro
finite elemen
Providenc
ngly, the obje
hip fracture
l model-gene
y and bone qua
ds
of models rep
f variation we
d intensity m
y, Mode 1 r
in anteversi
rized thicken
ns in highes
in medullary
shaft angle.
ed an experi
kwards and t
was modelle
pplies stress
e the location
crack propaga
[Morgan, 200
a function of
GIC/GIIC ratio
s
patterns and
luated in mod
d density of th
Mode 1, app
d to femora
ions in Mode
ure, but due
bone volume in
he other (+2�
f experimen
NG HIP FVARIAB
1), Brian Bu
ational Biomlorado Joinineering Sc
rs, including
wn to influenc
Recently, st
intersubject
ensity [Bryan,
one strains in
lated fall con
modelling eff
imum princi
igh fracture r
opagated crac
nt method (XF
ce, RI)
ective of this
behaviour i
erated subject
ality.
presenting the
ere created fro
model. Captur
represented s
ion angle.
ning of th
t modulus (
y cavity volum
The bound
ment simulat
to the side
ed with XFE
and energy-b
n of crack in
tion. Similar
01], the ener
f density [Coo
[Zimmerman
load at the o
dels represent
he population
plied load a
al size (Fig
2 resulted in
e to differen
n one (-2�) an
�). Fracture lo
ntal values
FRACTURBILITY IN
urks (1), Ray
mechanics Lt Replacem
cience Rese
g anatomy a
ce the likeliho
tatistical mode
variability
2010] and be
a population
ndition [Brya
forts have us
ipal strains
risk, the curre
cks utilizing t
FEM) in Abaq
[Liu, 201
s study was
in a series
ts with varyi
e most comm
om the statistic
ring 45% of t
scaling with
Mode 2 (8%
he bone w
(cortical) bon
me and decreas
dary conditio
ting an obliq
[Keyak, 200
EM in Abaqu
based criteria
nitiation and t
to modulus a
gy release ra
ok, 2010] with
n, 2009].
onset of fractu
ing the range
n. In the large
at fracture w
gure 1). Bo
decreased loa
nt mechanism
nd lower dens
oads were in t
[Keyak, 200
RE CONSSHAPE
ymond Kim
Lab, Univerment, Porter earch Group
and
ood
els
in
een
of
an,
sed
to
ent
the
qus
0].
to
of
ing
mon
cal
the
an
%)
with
ne,
ses
ons
que
0].
us,
to
the
and
ate,
h a
ure
of
ely
was
oth
ads
ms:
sity
the
00]
(F
w
se
D
A
m
fu
lo
co
ca
th
ro
Fi
m
Fi
fo
A
Th
O
R
B
et
M
B
C
56
30
SIDERINAND INT
(1,2), Mark T
rsity of Denvr Hospital, Dp, University
Figure 1). Wh
were observed
ensitive to nec
Discussion
As a complem
modelling crac
urther insight
oad at fractu
ombination o
an identify sh
hat are most s
obustness of re
igure 1: Load
modes of variat
igure 2: Crac
or first two mo
Acknowled
his study w
Osteosynthesis
References
ryan et al, M
t al, J Biomec
Med Eng Ph
iomech, 33:4
onference, 20
69-577, 2001
0:5877-5884,
NG INTERTENSITY
Taylor (3), P
ver, DenverDenver, CO,y of Southam
hile intertrocha
in all models
ck-shaft angle
n
ment to strain
ck initiation
into hip fra
re onset and
f fracture an
hape and bone
usceptible to
epair in the fra
d at onset of fra
tion compared
ck location in
odes of shape a
dgement
was support
and Trauma C
s
ed Eng Phys,
ch, 42:2171-2
hys, 32:991-9
499-502, 200
010. Morgan
. Zimmerman
2009.
RSUBJECY
Peter Laz (1)
r, CO, USA, USA; mpton, UK
anteric fractur
s, fracture loc
(Figure 2).
n and risk ev
and growth
acture, specif
d fracture pa
nd statistical
e quality char
fracture and
actured femur
racture for firs
d to Keyak [20
XFEM fractu
and density va
ted in part
Care Foundati
32:57-65, 20
2176, 2009. C
997, 2010.
00. Liu et
et al, J Biom
nn et al, Bio
CT
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;
re patterns
cation was
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modelling
racteristics
assess the
rs.
st two
000].
ure models
ariation.
by the
ion.
010. Bryan
Cook et al,
Keyak, J
al, ASB
mech, 34:
omaterials,
Presentation 1691 − Topic 23. Hip biomechanics S287
ESB2012: 18th Congress of the European Society of Biomechanics Journal of Biomechanics 45(S1)