President’s Note:

The ABAT board has been working hard as usual. As we continue to contemplate the future retirement of some of our most valued ABAT members, I find myself with mixed feelings. First, jealousy as I don’t see myself retiring anytime in the near future!! Second a feeling of nervousness as I wonder how can we possibly exist without them? However, after having the privilege of serving as ABAT president and being able to meet our newest passing ABAT’s, I am truly encouraged. They are young, smart, and hard working. They are also dedicated to ABAT and have been eager to become involved in ABAT committees and projects. Your ABAT board of directors continues to take on big projects such as Life Long Learning, putting education at the forefront (with webinars and learning opportunities), re-assessing our credentialing process, and taking on difficult discussions as to how we can attract new qualified individuals to ABAT. Our board of directors has also spent much time working with AACT updating our website, putting together a wonderful symposium at the national meeting, and of course, writing the ABAT exam, which would challenge any of our best candidates on a good day. Of all the duties of ABAT President, I have to say, meeting each of our members, talking with them and getting to know them has been the best part of this job. We each come from different practices, have different ideas, but we all have a common purpose- to preserve ABAT and make this the best professional membership we can. Therefore, whenever I get frustrated at work and think “what is the point?” I look at what my fellow colleagues are doing. I am always amazed at what they are accomplishing and it humbles me to be a part of this group. When I look over this newsletter and see all the publications and presentations and awards, I can only think…..”Damn girl, you better get back to work!”

WELCOME TO THE

2016 Winter ABAT

NeWSLETTER

WITH ALL YOUR LATEST NEWS

& UPDATES RELATED TO ABAT

Publications: 1. Bond M, Zantec N, Henry K, Engebretsen KM, Thomas A, and Stellpflug S. Intravenous Fat

Emulsion Does Not Significantly Alter Clotting Markers in Dabigatran-Treated Blood. Poster Presentation at the ACMT Annual Scientific Meeting, March 27-29, 2015 at Clearwater Beach, FL. Published in J of Med Toxicol, March 2015.

2. Nelson ZJ, Stellpflug SJ, and Engebretsen KM. What Can a Urine Drug Screening Immunoassay

Really Tell Us? J Pharm Pract. 2015 Apr 27. 3. Froberg BA, Levine M, Beuhler MC, Judge BS, Moore PW, Engebretsen KM, Mckeown NJ,

Rosenbaum CD, Young AC, and Rusyniak DE; ACMT Toxicology Investigators Consortium (ToxIC). Acute Methylenedioxypyrovalerone Toxicity. J Med Toxicol. 2015 Jun;11(2):185-94.

4. Burnett AM, Peterson BK, Stellpflug SJ, Engebretsen KM, Glasrud KJ, Marks J, and Frascone RJ.

The association between ketamine given for prehospital chemical restraint with intubation and hospital admission. Am J Emerg Med. 2015 Jan;33(1):76-9.

Oral Presentation:

“I think this is our best toxicology study so far. I hope you will be able to attend!”

Katzung KG, LeRoy JM, Boley SP, Stellpflug SJ, Holger JS, and Engebretsen, KM. Effect of

Norepinephrine on Cerebral Oxygenation in a Porcine Model of Propranolol Toxicity After

Maximization of High Dose Insulin (HDI) Therapy. With the following accolades:

Congratulations on behalf of the American College of Medical Toxicology! Your abstract entitled

"Randomized Controlled Study Comparing High Dose Insulin (HDI) to Vasopressors or Combination

Therapy in Refractory Toxin-Induced Cardiogenic Shock (TICS) ", reference 0116, and has been

accepted for presentation at the 2016 Annual Scientific Meeting, Huntington Beach, CA March 17-20,

2016. As one of the top scoring abstracts, you are awarded both platform and poster presentation.

Platform Session 1 Friday, March 18, 2016 - 8:00-9:00am Your assigned poster presentation: Friday, March 18, 2016, 8:00am-5:00pm Your authors with posters session: Friday, March 18, 2016, 12:30-1:30pm

Our latest research (my Toxicology fellow- Jenna LeRoy as PI) just received funding on a porcine

model of CV shock: Effect of Methylene Blue on Mortality in a Porcine Model of Amlodipine Toxicity.

This study was funded by the Emergency Medicine Foundation Grant /EMBRS and HealthPartners

Research foundation.

Welcome to New Secretary-Treasurer:

Greg Wedin Greg Wedin came to the Board of Directors meeting in San Francisco to observe the proceedings and to learn from our outgoing Secretary Treasurer David Baker. Reminder from the entire ABAT Board of Directors: Please remember that it is your responsibility to make sure that your e-mail address is up-to-date with both ABAT and the AACT office. The AACT office e-mail list is used to send out election information. You also need to make sure that you can receive surveys from survey monkey or give us an alternate email address that can take survey monkey so you can vote.

ABAT Symposium: Our Scientific Affairs committee (Co-Chaired by Howard McKinney and Fred Aleguas) organized the symposium entitled, “Protecting Your Liability in Practice: It’s Not a Roll of the Dice”. The symposium speakers were Jack Snyder, MD, PhD, JD, RAC and Allison Mueller PharmD, DABAT. The session covered some common pitfalls related to risky practices that may lead to legal action, even if there was not a bad outcome. They even discussed how and when to seek expert assistance. The real-life case examples were well received by the audience. For the 2016 meeting in Boston, Fred and Howard studied the needs assessment and developed the symposium title “Toxicology’s Mythologies”. The idea is both a historical overview of the sources of much of the dogma in clinical toxicology, and a discussion of some illustrative specific examples, along with exploration of the data and methods to measure the quality of this data. They have a speaker and are meeting the deadlines for the initial paperwork.

ABAT Business Meeting and 7th Annual Toxicology Residents/Fellows Reception:

On Sunday October 11, from 11:00am to 2pm, the ABAT meeting was held at the Perry’s on

the Embarcadero. We handed out 6 new ABAT Candidate certificates at the 2015 business

meeting: Sheila Goertemoeller, Rachael Gorodetsky, Dayne Laskey, Nicole Reid, Rachel

Schult, and Karen Thomas. The Annual Toxicology Residents/Fellows Reception was another

grand event this year due to the hard work from Bryan Hayes and Tom Kearney.

ABAT invited members and guests to attend the annual Business Meeting and ABAT Fellow’s

Reception. Again this year we secured an off-site location for our meeting and reception at the

Perry’s on the Embarcadero. We were able to step away from the meeting site and enjoy

breathtaking views of San Francisco Bay from the patio while we enjoyed a light lunch and

refreshments served in the restaurant’s enchanting patio. It was a chance to leave the

meeting hotel, walk a few blocks along the famous Embarcadero in San Francisco, to relax on

the patio with ABAT colleagues and enjoy the afternoon. We are looking forward to the

reception, which has grown to be one of our favorite events each year at the meeting in Boston

in 2016.

Other ABATs may be listed on the publication but the person who reported the publication gets the

credit. Greatly appreciate those who responded to the request for information –otherwise I’d have

nothing to report!-mw

Cynthia Morris-Kukoski:

Reports:

The FBI 2015 Customer Service Award was awarded to Cynthia for her assistance to the New Orleans Field Office. Her work on a case resulted in the conviction of a serial rapist via hair DFSA analysis for benzodiazepines, zolpidem, and ketamine. Congratulations!-mw

ABAT Publications and Announcements

(January 2015-December 2015)

Natalija Farrell:

Farrell NM, Wing HA, Burke PA, and Huiras P. Addition of tranexamic acid to a traumatic

injury massive transfusion protocol. Am J Health Syst Pharm 2015;72(12):1059-64.

Employee of the Month: November 2015

New Position:

o Clinical Pharmacy Specialist – Emergency Medicine

o Rhode Island Hospital

o Providence, RI

Susan Gorman:

Huang, E, Pillai S, Bower WA, Hendricks K, Guarnizo JT, Hoyle J, Gorman SE, Boyer AE,

Quinn C, and Meaney-Delman D. Antitoxin treatment of inhalation anthrax: A systematic

review. Health Security 2015; 13(6): 365-77.

Henry Spiller:

Spiller HA, Good TF, Spiller NE, Aleguas A.Vitamin D exposures reported to US poison Centers 2000-2014: Evaluation of temporal trends and outcomes. Human Exper Toxicol 2015, first published on October 30, 2015

Spiller HA, Wiles D, Russell JL, Casavant MJ. Review of toxicity and trends in use of Tiagabine as reported to US Poison centers 2000 to 2012. Human Exper Toxicol 2015 first published on March 29, 2015

Onders B, Casavant MJ, Spiller HA, Chounthirath T, Smith GA. Marijuana exposure among United States children younger than six years old. Clin Pediatr 2015 (Accepted – In press)

Russell JL, Spiller HA, Baker D. Markedly Elevated Carbamazepine-10,11-epoxide Concentration in a Fatal Carbamazepine Ingestion Case Reports Med 2015 Article ID 369707 http://dx.doi.org/10.1155/2015/369707

Spiller HA, Mowry JB, Aleguas A, Griffith JRK, Goetz R, Ryan ML, Bangh S, Klein-Schwatrz W, Schaeffer S, Casavant MJ. An observational study of the factor Xa inhibitors rivaroxaban and apixaban as reported to 8 Poison Centers. Ann Emerg Med (accepted – in press)

Spiller HA, Strauch J, Essing-Spiller SJ, Burns G. Thirteen years of Oxcabazepine exposures reported to US Poison centers: 2000 to 2012. Human Exper Toxicol 2016 (accepted – in press)

Meetings:

o Spiller HA, Good TF, Aleguas A. 15 years of Vitamin D exposures reported to US poison Centers. Clin Toxicol 2015;53:242

Presented at European Association of Poison Centres and Clinical Toxicologists XXXV International Congress, St. Julian's, Malta, May 26-29 2015

o Onders B, Casavant MJ , Spiller HA, Chounthirath T ,Smith GA Marijuana Exposure

Among United States Children Younger than Six Years Old. Presented at Society for Advancement of Violence and Injury Research 2015, in

New Orleans March 11-13, 2015

o Spiller HA, Griffith JRK, Aleguas A, Ryan ML, Mowry J, Bangh SA, Klein-Schwartz W, Schaeffer S, Goetz R. Rivaroxaban and apixaban ingestions reported to 8 Poison Centers. Clin Toxicol 2015:53:681-682

o Malis EM, Spiller HA, Casavant MJ. Community bus-stop advertising of poison center: does it work? Evaluation of a unique marketing strategy to expand Poison Center utilization. Clin Toxicol 2015:53:733

o Kamboj AK, Spiller HA, Casavant MJ Chounthirath T, Smith GA. Medication errors associated with cardiovascular drugs. Clin Toxicol 2015:53:670

o Onders B, Casavant MJ, Spiller HA, Chounthirath T, Smith GA. Marijuana exposures among United States Children younger than six years old. Clin Toxicol 2015:53:691

o Tomasi S, Roberts KJ, Stull J, Spiller HA, McKenzie LB. Adult Exposures to Veterinary Pharmaceuticals (1999-2013) Clin Toxicol 2015:53:763

o Tomasi S, Roberts KJ, Stull J, Spiller HA, McKenzie LB. Pediatric Exposures to Veterinary Pharmaceuticals (1999-2013) Clin Toxicol 2015:53:762

o Behrman AD, Goertemoeller S, Spiller HA. Retrospective review of Phenibut exposures reported to Ohio poison control centers. Clin Toxicol 2015:53:272

o Spiller HA, Burns GD, Thornton D, Casavant MJ. N-OH-PABA, the active hydroxyl metabolite of benzocaine, can produce MetHB in control blood. Clin Toxicol 2015:53:648

Presented at the North American Congress of Clinical Toxicology, San Francisco CA Oct 8-12 2015

o Tomasi S, Roberts KJ, Stull J, Spiller HA, McKenzie LB Pediatric Exposures to

Veterinary Pharmaceuticals (1999-2013) Presented at 143rd American Public Health Association annual meeting and

exposition, Chicago IL, Oct 31-Nov 4, 2015

In addition to all of the publications and presentations, Rick was still active with his soccer team. They

did not win the tournament cup. Alas they lost the final game. Great job!-mw

Bryan Hayes:

Azab SM, Hirshon JM, Hayes BD, El-Setouhy M, Smith GS, Sakr ML, Tawfik H, Klein-Schwartz W. Epidemiology of acute poisoning in children presenting to the poisoning treatment center at Ain Shams University in Cairo, Egypt, 2009-2013. Clin Toxicol (Phila). 2016 Jan;54(1):20-6.

Hines MC, Al-Salamah T, Heil EL, Mallemat H, Witting MD, Johnson JK, Winters ME, Hayes BD. Resistance Patterns of Escherichia coli in Women with Uncomplicated Urinary Tract Infection Do Not Correlate with Emergency Department Antibiogram. J Emerg Med. 2015 Dec;49(6):998-1003.

National Presentation:

A Look at Lipid Emulsion as a Rescue Agent in Toxicology. o 50th American Society of Health-System Pharmacists Mid-Year Clinical Meeting. New

Orleans. December 2015.

Daniel Cobaugh:

Cobaugh DJ. Celebrating 50 ASHP Midyear Clinical Meetings. Am J Health Syst Pharm. 2015 Dec 1;72(23):2059.

Cobaugh DJ. Opposing pharmacists' participation in capital punishment: The right thing to do. Am J Health Syst Pharm. 2015 Aug 15;72(16):1355.

Cobaugh DJ. A professional imperative: developing pharmacy residents as the next generation of practice-based researchers. Am J Health Syst Pharm. 2015 Apr 15;72(8):615.

Cobaugh DJ. Where does AJHP go next? Am J Health Syst Pharm. 2015 Mar 15;72(6):437.

Cobaugh DJ, Miller MJ, Pham TT, Krenzelok EP. Risk of major morbidity and death in older adults with suicidal intent: a cross-sectional analysis from the National Poison Data System, 2000-2009. J Am Geriatr Soc. 2015 Mar;63(3):501-7.

Presentations:

Considerations in Publishing: Guidance and Panel Discussion with Pharmacy Journals o AACP & AFPC Annual Meeting, July 13, 2015

ABAT Committee Updates:

Scientific Affairs Committee:

The ABAT Board would like to request suggestions for future topics for upcoming ABAT

symposiums. In the past the following topics have been covered:

1997: Drugs of Abuse 1998: Calcium Channel toxicity 1999: Bites, Stings, Plants 2000: Evidence Based Medicine 2001: Mechanisms to Clinical Effects 2002: Oximes in OP 2003: Gap between Science and Practice 2004: Ipecac 2005: Calcium antagonist OD 2006: That's not MY drug screen and cleaning up of the 21st century Love canal 2007: Voodoo in the 21st Century-RADIATION: Mechanisms, Detection, and Treatment 2008: Cutting Edge Medication Safety Update:

Do Poison Centers and Clinical Toxicologists Have a Role? 2009: Momma Don’t Take My Cytochrome Away 2010: Don’t Tread on Me 2011: Drugs of Tomorrow & Challenges of Today: Synthetic Congeners 2012: Evidence Based Practice: The Treatment of Rhabdomyolysis 2013: Forensic Toxicology: Applied Quantitative and Qualitative Testing 2014: Clinically Relevant Herb-Drug Interactions: Past, Present, Future 2015: Protecting Your Liability in Practice: It’s Not a Roll of the Dice If you have any suggestions for upcoming ABAT symposiums, please contact Fred Aleguas at aaleguas@gmail.com.

Certification Renewal Committee:

Based upon revised information received, there are 18 ABAT members up for

certification renewal in 2016 and include : Jess Benson, Barbara Crouch, Michele

Zanter, Tom Kearney, Cynthia Morris-Kukoski, Kevin Rynn, Susan Smolinske, Christine

Stork, Anna Rouse Dulaney, Fred Aleguas, Stacey Bangh, Nicole Ries, Sharon

Ternullo, Ilene Anderson, Bryan Hayes, Raymond Ho, Keith McCain, and Ashely Webb.

An email has been sent out to all of them already since there are some changes to the

process. This upcoming year is the first time that the Life Long Learning Addendum to

the form will be completed as well. Since five years of information will not be available

for this addendum, it is understood that the items completed will be phased in. For

example, the LLL document has the following requirements: 30 CEU’s over 5 years, 4

LLSA Articles or LLSA Live sessions at NAACT within 5 years, and 2 Journal Club

Webinars over the 5 years. Since the arrangement of the LLSA Articles has not been

solidified as of this time, this piece will not be evaluated. The certification renewal form

and the LLL addendum have been emailed to those 18 members. All forms are due by

7/1/2016. Along with this newsletter, we are sending copies of the LLL form and the

certification renal form to help prepare for the next renewal cycle. The certification

renewal committee will then begin the process of evaluating the submissions. Feel free

to contact Dawn Sollee if you have any questions at sollee@poison.ufl.edu.

Announcements/Requests:

ABAT is looking for members who are interested in being part of the ABAT Education

Committee. We are looking to form a special subcommittee of those who are interested in

tackling the project of bringing awareness and education to EM Clinical Pharmacists, CSPIs,

and other possible organizations. We are working towards their possible opportunity to

become involved in becoming an ABAT diplomate. If you are interested, please contact Bryan

Hayes at bryanhayes13@gmail.com

LATE BREAKING NEWS

Jon Thompson has retired from his position as director of the Southeast Texas Poison Center.

He said he was starting on his next verture: bonsai gardening. Best to Jon in his new ‘career’.

Booth Volunteers in Action!!

************Meet our newest ABAT Diplomats in the Spring Newsletter *****************