virginia modeling, analysis and simulation center
TRANSCRIPT
Virginia Modeling, Analysis and Simulation Center
Modeling & Simulation Applications in Bio-MedicineDr. R. Michael Robinson
1030 University BoulevardSuffolk, VA 23435
June 15, 2010
Virginia Modeling, Analysis and Simulation CenterOld Dominion University Virginia Modeling, Analysis and Simulation Center
APPLIED RESEARCH AREAS• General BOK/Applied Principles of M&S (fundamental concepts: theory of
simulation, distributed simulation, interoperability, V&V, etc.)
• General / Social Science (non-medical life sciences: ecology, climate modeling, oceanography, biochemistry, etc.)
• Defense/HLS (interfacing M&S capabilities with C2, M&S OR support, analysis and visualization of military or HLS system problems)
• Medical & Healthcare (augmented VR, VOR, VR Rehabilitation, and physical systems modeling, etc.)
• Business & Supply Chain Modeling / M&S in Eng (changes in traditional eng disciplines: enterprise decision support, product design, optimization and more)
• Transportation (M&S to solve multimodal {road, rail and air} transportation problems – micro/macroscopic travel)
• Virtual Environments (domain specific virtual intelligent agents, construction of VE, flexible crowd models, task level planning of agents and immersive simulations)
• Education & Game-Based Learning – serious games to train soldiers, workforce and help achieve national STEM objectives.
Old Dominion University Virginia Modeling, Analysis and Simulation Center
APPLIED RESEARCH AREAS• General BOK/Applied Principles of M&S (fundamental concepts: theory of
simulation, distributed simulation, interoperability, V&V, etc.)
• General / Social Science (non-medical life sciences: ecology, climate modeling, oceanography, biochemistry, etc.)
• Defense/HLS (interfacing M&S capabilities with C2, M&S OR support, analysis and visualization of military or HLS system problems)
• Medical & Healthcare (augmented VR, VOR, VR Rehabilitation, and physical systems modeling, etc.)
• Business & Supply Chain Modeling / M&S in Eng (changes in traditional eng disciplines: enterprise decision support, product design, optimization and more)
• Transportation (M&S to solve multimodal {road, rail and air} transportation problems – micro/macroscopic travel)
• Virtual Environments (domain specific virtual intelligent agents, construction of VE, flexible crowd models, task level planning of agents and immersive simulations)
• Education & Game-Based Learning – serious games to train soldiers, workforce and help achieve national STEM objectives.
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Medical M&S Application Areas
• Training and Diagnostic Tools• Patient Care and Treatment• Infectious Disease Spread• Hospital Operations
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Training and Diagnostic Tools
• Used in tandem with a standardized patient (SP)• “Tracked VPS” or wireless control• Substitutes abnormal sounds for healthy sounds, supporting
diagnostic training• Licensed by Cardionics Inc.• Partners include ODU, EVMS/
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Anterior Heart & Lung Sound Locations ( 12)
Posterior Heart & Lung Sound Locations (14)
Virtual Pathology Stethoscope
Training and Diagnostic Tools
Old Dominion University Virginia Modeling, Analysis and Simulation Center
•Computer generated dynamic organ models
•Sonograph of fetus is shown•Virtual fetus is placed in
real environment on SP that is not pregnant.
•Practice proper placement and hand-eye coordination
•Selection of injury/disease effects
•ODU, EVMS
Virtual Pathology Sonography
Training and Diagnostic Tools
Old Dominion University Virginia Modeling, Analysis and Simulation Center
• Virtual hospital for nurse education• Interact patient avatars• Variety of illnesses and injuries• Nurses trained on admittance interviews
• Patient priority• Immediate diagnostic requirements• Increased efficiency and accuracy
• Virtual Patient Library• VMASC/ODU, EVMS
Monarch General
Training and Diagnostic Tools
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Mechanical engineering strength and fatigue analyses
Strength models of bone and soft tissue (cadavers)
Simulated injuries
Diagnosis/treatment recommendations
Future work will develop models to treat trauma and diseases on a patient specific basis
Ankle Joint Injuries
Using Xbox 360 for Rehabilitation of Brain Injured Patients
• Improve patents’ cognitive and motor skills• Sponsored by Office of the Secretary of Defense, DoD.• SBIR Phase I with MYMIC LLC.
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Patient Care and Treatment
Modeling Communication Helping Children with Severe Autism Communicate
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Patient Care and Treatment
Funded by Microsoft ResearchPartner: Clermont University, CA
Virtual RealityHelping Children with Cerebral Palsy Walk
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Patient Care and Treatment
•Opposed helicopter extraction model
•Improved modeling can be used to improve tactical planning
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Patient Care and Treatment
Development and Assessment of Physical Training Regimes
•Assess importance of individual physical fitness on survivability
•Data collection funded by ONR. Measure 12 meter “rush speeds
0.00%
50.00%
100.00%
0 15 30 45 60 75 90 105 120 135 150
Survivability vs Rushing Distance (m)
Survival Slow (2.34m/sec)
Survival Fast (3.78 m/sec)
Infectious Disease Spread
•Funded by NIH•Partners: ODU, Johns Hopkins, U. Maryland, U. Michigan
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Tick-Borne Diseases: Rift Valley Fever •Collecting ticks from coastal Virginia sites from May through October•Develop and use model to predict optimal control strategy
Infectious Disease Spread
• Assess compliance to infection control protocols• Analyze potential spread of a pathogen• Increase awareness through visualization• Funded by NSF• Partners: ODU, Murray State U., Marymount U. , U. of TN
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Cholera Model structure
Optimal Strategies for Controlling Cholera Outbreaks
Disaster Medical Assistance Team – DMAT Gaming Solution for Training and Assessment
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Hospital Operations
Funded by Mymic LLC through SBIR Phase I and II (2007-2010) Partners: Mymic LLC, Forterra System Inc
Goal: Improve medical response team efficacy using research oriented short experiments and game based training
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Hospital Operations
Populationwith
Non-EmergentNeed
fracton of popreceiving treatment 1B
PopulationDirected byEducation1
total market
enrollment1insurancecoverage1
insurance coverageintervention effects on PCP
utilization
utilization1B
repopulation life
education1
contact1
education interventioneffects on PCP utilization
PopulationDirected byInsurance
Coverage1utilization1A PopulationReceiving
PCPTreatment
aggregate1A
aggregate1B
fraction of popreceiving treatment 1A
TreatedPopulations
flow1
repopulation
aggregate life1B
aggregate life 1A
flow1 life
fraction of popreceiving treatment at
PCP
PopulationDirected byInsurance
Coverage2
PopulationDirected byEducation2
PopulationReceivng ED
Treatment
utilization2A
utilization2B
aggregate2A
aggregate2B
flow2
enrollment2
insurancecoverage2
effectiveness of insuranceintervention 2A
effectiveness ofeducation inervention 2B
education interventioneffects on ED utilization
contact2
education2
insurance coverageintervention effects on ED
utilization aggregate life 2A
aggregate life 2B
flow2 life
fraction of pop receivingtreatment in ED
fraction of popreceiving treatment 2A
fraction of popreceiving treatment 2B
Modeling the Sensitivity of Inappropriate Emergency Department Utilization
Patient Arrival
Triage Process and Registration
Test? Doctor/Nursetreatments
Admitted or/Depart from ER
Pod A
Pod B
Pod C
T
F
CAT 4
Wait for Bed and
assessment
Bed and Baseline Assessment
Bed and Baseline Assessment
Bed and Baseline Assessment
Test Evaluation
TestingCAT1
Bed available
Test? Doctor/Nursetreatments
T
F
Test Evaluation
TestingCAT 2/3
Test? Doctor/Nursetreatments
TF
Test Evaluation
TestingCAT 4
Hospital Operations
Old Dominion University Virginia Modeling, Analysis and Simulation Center
Optimizing Emergency Department Resources
Backup Slides
Old Dominion University Virginia Modeling, Analysis and Simulation Center
• Developing an internet based rehabilitation program for war-fighters with functional hearing loss secondary to blast and/or mTBI (OSD, SBIR-phase I and II)• Dr. Stacie Ringleb• ODU
• Developing VR assessment modules to determine return to duty and affective (OSD)• Dr. Stacie Ringleb• ODU
• Improving VR based rehabilitation systems to treat stroke patients and collecting fMRI data on these patients (ODU’s Office of Research)
Old Dominion University Virginia Modeling, Analysis and Simulation Center
• GaMeTT: Create a computer game-based software tool to track, assess, and train medical support teams to operate under stressful conditions. (Mymic LLC)• Dr. Gianluca De Leo• VMASC/ODU, Mymic LLC, Forterra Inc
• Iphone Application for Emergency Preparedness (Hampton Roads Planning District Commission )• Dr. Gianluca De Leo• VMASC/ODU
Old Dominion University Virginia Modeling, Analysis and Simulation Center