use of potentially inappropriate medications common among elderly

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PharmacoEconomics & Outcomes News 427 - 30 Aug 2003 Potentially inappropriate medications are commonly prescribed for elderly patients in residential-care facilities, say US-based researchers. Their cohort study, conducted in residential-care facilities in the Puget Sound region of Washington State, US, used data for 282 patients aged 65 years to assess the appropriateness of medication use. The study revealed that 22% of residents received at least one potentially inappropriate medication, * most commonly tricyclic antidepressants such as amitriptyline (3.5%) and doxepin (2.5%), antihistamines such as diphenhydramine (2.9%), urinary antispasmodics such as oxybutynin (3.5%) and long-acting benzodiazepines such as clonazepam (1.8%). During the 1-year follow-up, the incidence of new use of potentially inappropriate medications was 0.1 per 100 person-days. * based on 1997 Beers criteria Gray SL, et al. Potentially inappropriate medication use in community residential care facilities. Annals of Pharmacotherapy 37: 988-993, No. 7-8, Jul-Aug 2003 800950997 1 PharmacoEconomics & Outcomes News 30 Aug 2003 No. 427 1173-5503/10/0427-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Page 1: Use of potentially inappropriate medications common among elderly

PharmacoEconomics & Outcomes News 427 - 30 Aug 2003

■ Potentially inappropriate medications arecommonly prescribed for elderly patients inresidential-care facilities, say US-based researchers.Their cohort study, conducted in residential-carefacilities in the Puget Sound region of WashingtonState, US, used data for 282 patients aged ≥ 65 yearsto assess the appropriateness of medication use. Thestudy revealed that 22% of residents received at leastone potentially inappropriate medication,* mostcommonly tricyclic antidepressants such asamitriptyline (3.5%) and doxepin (2.5%),antihistamines such as diphenhydramine (2.9%),urinary antispasmodics such as oxybutynin (3.5%) andlong-acting benzodiazepines such as clonazepam(1.8%). During the 1-year follow-up, the incidence ofnew use of potentially inappropriate medications was0.1 per 100 person-days.* based on 1997 Beers criteria

Gray SL, et al. Potentially inappropriate medication use in communityresidential care facilities. Annals of Pharmacotherapy 37: 988-993, No. 7-8,Jul-Aug 2003 800950997

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PharmacoEconomics & Outcomes News 30 Aug 2003 No. 4271173-5503/10/0427-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved