universidad ced san pablo centre university of alberta ... · microbial biofilms methods and...

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News 3/2014 Life Sciences

E. G. Armitage, Universidad CED San Pablo Centre for Metabolomics and Bioanalysis, Boadilla del Monte, Spain; H. L. Kotze, University of Manchester Manchester Institute of Biotechnology, Manchester, UK; K. J. Williams, University of Manchester Manchester Cancer Research Centre, Manchester, UK

Correlation-based network analysis of cancer metabolismA new systems biology approach in metabolomics

With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becom-ing increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals specific to the metabolomics community.

Features 7 This book presents a pioneering technique for analyzing metabolites 7 Explores the metabo-lome as the closest entity to the phenotype of a biological system 7 A useful tool for introducing metabolomics to the cancer research community

Contents An overview of Cancer metabolism.- Cancer hypoxia and the tumour microenvironment as effectors of cancer metabolism.- Metabolic fingerprinting of in vitro cancer cell samples.- Network-based correlation analysis of metabolic fingerprinting data.- Case study: Systems biology of HIF metabolism in cancer.- Case study: Systems biology of chemotherapy resistance in hypoxic cancer.- Index.

Fields of interestSystems Biology; Metabolomics; Cancer Research

Target groupsResearch

Product categoryBrief

Due March 2014

2014. I, 74 p. 19 illus., 15 in color. (SpringerBriefs in Systems Biology) Softcover7 * € (D) 53,49 | € (A) 54,99 | sFr 67,007 € 49,99 | £44.99ISBN 978-1-4939-0614-7

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M. Asif, University of Alberta, Edmonton, AB, Canada; M. Iqbal, National Agricultural Research Centre, Islamabad, Pakistan; H. Randhawa, Lethbridge Research Centre, Lethbridge, AB, Canada; D. Spaner, University of Alberta, Edmonton, AB, Canada

Managing and Breeding Wheat for Organic SystemsEnhancing Competitiveness Against Weeds

Genetically uniform cultivars in many self-polli-nated cereal crops dominate commercial produc-tion in high-input environments especially due to their high grain yields and wide geographical adaptation. These cultivars generally perform well under favorable and high-input farming systems but their optimal performance cannot be achieved on marginal/organic lands or without the use of external chemical inputs (fertilizers, herbicides and pesticides). Cereal breeding programs aim at evaluating candidate lines/cultivars for agronomic, disease and quality traits in a weed free environ-ment that makes it impossible to identify traits conferring competitive ability against weeds. Moreover, quantification of competitive ability is a complex phenomenon which is affected by range of growth traits.

Features 7 Plant breeding techniques and experimental designs for organically managed lands 7 Wheat breeding strategy for enhanced competitive abili-ties 7 Practical examples and comparisons with other cereal crops

Contents Wheat: The Miracle Cereal.- Crop Competitive-ness.- Strategies to enhance competitive ability.- Breeding wheat for organic agriculture.- Future Perspectives.

Fields of interestPlant Sciences; Plant Breeding/Biotechnology; Plant Physiology



Due April 2014

2014. X, 60 p. 10 illus. in color. (SpringerBriefs in Agriculture) Softcover7 approx. * € (D) 42,79 | € (A) 43,99 | sFr 49,507 approx. € 39,99 | £33.99ISBN 978-3-319-05001-0

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R. G. Bailey, USDA Forest Service, Fort Collins, CO, USA

EcoregionsThe Ecosystem Geography of the Oceans and Continents

Global warming and human-driven impacts are changing the World’s ecological zones. This book applies the principles described in Bailey’s Ecosystem Geography: From Ecoregions to Sites, 2nd ed. (Springer 2009, 1st ed. 1996) to describe and characterize the major terrestrial and aquatic ecological zones of the Earth.

Features 7 This is a new edition of a well-received text and it is essential reading for land managers, research-ers and graduate students in ecology, landscape ar-chitecture and regional planning 7 A significant contribution to a long tradition of classifying and studying the world’s ecological regions or ecore-gions 7 Details the use of eco regional patterns to design monitoring networks and sustainable landscapes

Contents 1. Introduction 2. Oceanic Types and Their Con-trols 3. The Ecoregions of the Oceans 4. Continen-tal Types and Their Controls 5. Ecoregions of the Continents: The Polar Ecoregions 6. The Humid Temperate Ecoregions 7. The Dry Ecoregions 8. The Humid Tropical Ecoregions 9. Mountain Ecoregions 10. Ecoregion Redistribution under Climate Change 11. Fire Regimes in Different Ecoregions and Their Management Implications 12. Applications of Ecoregional Patterns 13. Sum-mary and Conclusion Appendix A: Air Masses and Frontal Zones Appendix B: Common and Scientific Names Appendix C: Conversion Factors.

Fields of interestEcology; Geography (general); Landscape/Re-gional and Urban Planning


Product categoryGraduate/Advanced undergraduate textbook

Due April 2014

2nd ed. 2014. XIV, 198 p. 134 illus., 54 in color. Hardcover7 * € (D) 74,89 | € (A) 76,99 | sFr 93,507 € 69,99 | £62.99ISBN 978-1-4939-0523-2

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www.springer.com/978-1-4939-0614-7



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Life Sciences springer.com/NEWSonline

S. Cambridge, University of Heidelberg, , Germany (Ed)

Photoswitching ProteinsMethods and Protocols

Contents Photoinduced Damage Resulting from Fluores-cence Imaging of Live Cells.- Modification of Purified Proteins with Photochemical Protection Compounds for High-Resolution Photoactivation of Protein Function In Vitro and In Vivo.- Opto-chemical Activation of Kinase Function in Live Cells.- Photoswitching of Cell Surface Receptors Using Tethered Ligands.- Photocontrol of AMPA Receptors with a Photochromic Ligand.- Pho-toconversion of CFP to Study Neuronal Tissue with Electron Microscopy.- Light-Inducible Gene Regulation with Engineered Zinc Finger Proteins.- Manipulation of Plasma Membrane Phosphoinositides using Photoinduced Protein-protein Interactions.- A Roadmap to Applying Optogenetics in Neuroscience.- Salvaging Ruins: Reverting Blind Retinas into Functional Visual Sensors.- Photoactivated Adenylyl Cyclases as Optogenetic Modulators of Neuronal Activity.- Structural Basis of Photoswitching in Fluorescent Proteins.- Using Photoactivatable GFP to Track Axonal Transport Kinetics.- In Vivo Cell Tracking Using PhOTO Zebrafish.- In vivo Optogenetics for Light-induced Oxidative Stress in Transgenic Ze-brafish Expressing the KillerRed Photosensitizer Protein.- Photoactivatable Fluorescent Proteins for Super-Resolution Microscopy.- pcSOFI as a Smart Label-based Superresolution Microscopy Technique.

Fields of interestProtein Science; Biological Microscopy; Neurobi-ology

Target groupsProfessional/practitioner

Product categoryContributed volume

Due April 2014

2014. XVI, 284 p. 55 illus., 50 in color. (Methods in Molecular Biology, Volume 1148) Hardcover7 * € (D) 101,64 | € (A) 104,49 | sFr 126,507 € 94,99 | £85.50ISBN 978-1-4939-0469-3

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E. Carpana, Unità di apicoltura e bachicoltura, Bologna, Italy; M. Lodesani, CRA, Bologna, Italy (Rédacteurs)

Patologia e avversità dell’alveareFeatures 7 Manuale ricco di indicazioni pratiche per la gestione dei problemi sanitari nell'azienda apistica 7 Un guida per conoscere e affrontare le patologie e le avversità ambientali che minacciano la salute delle api 7 Si riportano le più recenti acquisizioni delle ricerca nonché le dirette espe-rienze degli autori

Contents 1 Introduzione: cenni storici sulle patologie delle api, diffusione geografica e impatto economico delle principali patologie delle api, nozioni di epidemiologia, profilassi e terapia.- 2 Difese natu-rali della colonia d’api contro le patologie: difese individuali e immunità sociale, recenti acquisi-zioni sui meccanismi molecolari di difesa contro le infezioni batteriche.- 3 Malattie batteriche: peste americana, peste europea, setticemie e altre infezioni batteriche.- 4 Virosi: le infezioni virali delle api, tecniche diagnostiche per la ricerca dei virus delle api.- 5 Micosi: ascosferosi, aspergillosi, bettsia alvei.- 6 Nosemiasi.- 7 Malattie da protozoi: amebiasi, altri protozoi associati alle api.- 8 Acari parassiti: varroasi, acariasi respiratoria, altri acari associati alle api.- 9 Insetti parassiti e predatori (lepidotteri, ditteri, coleotteri, imenotteri).- 10 Predatori dell’alveare (anfibi e rettili, uccelli, mammiferi).- 11 Anomalie, disordini di origine incerta, malattie non parassitarie, patologia dell’a-pe regina.- 11 Avvelenamenti da agrofarmaci.- 12 Problemi legati ai trattamenti farmacologici.- 13 Approccio integrato alla gestione sanitaria degli apiari.- 14 Legislazione sanitaria in apicoltura.

Fields of interestEntomology; Veterinary Medicine



Pubblicazione prevista per il mese di May 2014

2014. Approx. 450 pagg. 125 figg., 100 a colori. Cartonato7 approx. * € (D) 59,66 | € (A) 61,34 | sFr 74,507 approx. € 55,76 | £50.99ISBN 978-88-470-5649-7

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S. S. da Silva, A. K. Chandel, University of São Paulo, Lorena/SP, Brazil (Eds)

Biofuels in BrazilFundamental Aspects, Recent Developments, and Future Perspectives

This book discusses the commercialization of bio-fuels and the Brazilian government policies for the promotion of renewable energy program in Brazil, which could be a learning module for several countries for implementing biofuels policy to im-prove their socioeconomic status and make them energy independent. Researchers in academia and industries, policy makers, and economic analysts will be assisted by important source of informa-tion in their ongoing research and future perspec-tives. This book will benefit graduate and post-graduate students of chemical and biochemical engineering, forestry, microbiology, biochemistry, biotechnology, applied chemistry, environmental science, sustainable energy, and biotech business disciplines by signifying the applied aspects of bio-energy production from various natural sources and their implications.

Features 7 First uniquely designed scientific and technical literature on bioenergy production in the context of Brazil 7 Covers technological updates on biomass processing, system biology, microbial fer-mentation, catalysis, regeneration and monitoring of renewable energy and recovery process 7 De-tailed techno-economic analysis, covering climate change, geo-political analysis of bioenergy and green transportation fuels at industrial scale

Contents

Fields of interestMicrobiology; Microbial Ecology; Renewable and Green Energy



Due May 2014

2014. X, 521 p. 109 illus., 56 in color. Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-3-319-05019-5

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G. Donelli, Fondazione Santa Lucia IRCCS Microbial Biofilm Laboratory, Rome, Italy (Ed)

Microbial BiofilmsMethods and Protocols

Contents Methods for Dynamic Investigations of Surface Attached in vitro Bacterial and Fungal Biofilms.- Aqueous Two-Phase System Technology for Patterning Bacterial Communities and Biofilms.- Quorum Sensing in Gram-Positive Bacteria: Assay Protocols for Staphylococcal agr and enterococ-cal fsr Systems.- Advanced Techniques for in situ Analysis of the Biofilm Matrix (Structure, Composition, Dynamics) by Means of Laser Scanning Microscopy.- Multiplex Fluorescence in situ Hybridization (M-FISH) and Confocal Laser Scanning Microscopy (CLSM) to Analyse Multi-species Oral Biofilms.- Field Emission Scanning Electron Microscopy of Biofilm-Growing Bacteria Involved in Nosocomial Infections.- Experimental Approaches to Investigating the Vaginal Biofilm Microbiome.- Imaging Bacteria and Biofilms on Hardware and Periprosthetic Tissue in Ortho-paedic Infections.- Animal Models to Evaluate Bacterial Biofilm Development.- Animal Models to Investigate Fungal Biofilm Formation.- Non-Mammalian Model Systems to Investigate Fungal Biofilms.- Microbiological Methods for Target-Oriented Screening of Biofilm Inhibitors.- In vitro Screening of Antifungal Compounds Able to Counteract Biofilm Development.- Biofilm Matrix-Degrading Enzymes.- Efficacy Evalua-tion of Antimicrobial Drug-Releasing Polymer Matrices.- Antibiotic Polymeric Nanoparticles for Biofilm-Associated Infection Therapy.- Pharmaco-kinetics and Pharmacodynamics of Antibiotics in Biofilm Infections of Pseudomonas aeruginosa in vitro and in vivo.- Contribution of Confocal Laser Scanning Microscopy in Deciphering Biofilm Tridimensional Structure and Reactivity. [...]

Fields of interestMicrobiology; Bacteriology



Due April 2014

2014. XIV, 410 p. 100 illus., 63 in color. (Methods in Molecular Biology, Volume 1147) Hardcover7 * € (D) 117,69 | € (A) 120,99 | sFr 146,507 € 109,99 | £99.00ISBN 978-1-4939-0466-2

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G. W. Fernandes, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; J. C. Santos, Universidade Federal de Uberlândia, Uberlândia, Brazil (Eds)

Neotropical Insect GallsContents Introduction · Historical perspective and future of insect gall studies in the tropics; G. Wilson Fernandes & Rogério P. Martins.- Part One. The galls induced by Insects.- Developmental anatomy of galls in the Neotropics: arthropods stimuli vs. host plant constraints; Rosy Mary dos Santos Isaias et al.- Functional gradients in insect gall tissues: studies on Neotropical host plants; Denis Coelho de Oliveira, Rosy Mary dos Santos Isa-ias.- Gall morphotypes in the Neotropics: why is it necessary to standardize them?; Rosy Mary dos Santos Isaias et al.- Taxonomic diversity of galling insects; Marco Antonio A. Carneiro, G. Wilson Fernandes.- Part Two. The evolutionary ecology of Neotropical insect galls.- Population ecology of galling arthropods in the Neotropics; Milton de Souza Mendonça, Jr.- Plant defenses against gall-inducing insects; Milton Barbosa, G. Wilson Fernandes.- An unexpected selection effect on Waltheria indica L. gall-size distribution; José M. A. Figueiredo et al.- Forest insect galls density distribution between the canopy and understorey: Neotropical, Gondwanan or global patterns?; Sérvio Pontes Ribeiro et al.- Galls as indicators of habitat quality and stress; G. Wilson Fernandes et al.- Structure of galling insect community associ-ated with Copaifera langsdorffii (Fabaceae): the role of host plant phenology; Marcílio Fagundes et al.- Caryocar brasiliense: evidence of competition among galling insects; Germano Leão Demolin Leite, Ronnie Von dos Santos Veloso.- Baccharis: a Neotropical model system of galling studies; G. Wilson Fernandes et al.- Part Three. The biogeog-raphy of Neotropical galling insects. [...]

Fields of interestEntomology; Animal Ecology; Biodiversity



Due May 2014

2014. Approx. 300 p. 101 illus., 50 in color. Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-94-017-8782-6

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A. Filloux, Imperial College London, London, UK; J.‑L. Ramos, Consejo Superior Investigaciones Científ, Granada, Spain (Eds)

Pseudomonas methods and protocolsContents Gene Transfer: Transduction.- Gene Transfer: Transformation/Electroporation.- Gene trans-fer: Conjugation.- Pseudomonas Bacteriophage Isolation and Production.- Genotyping Methods.- Drug Susceptibility Testing by Dilution Meth-ods.- Plate-based Assay for Swimming Motility in Pseudomonas aeruginosa.- Plate-based Assay for Swarming Motility in Pseudomonas aeruginosa.- Motility Assay: Twitching Motility.- Qualitative and Quantitative Assays for Flagellum-mediated Chemotaxis.- Microscopic Analysis: Morphotypes and Cellular Appendages.- Determination of Lipolytic Activities.- Elastinolytic and proteolytic enzymes.- In vitro Assays to Monitor the Activity of Pseudomonas aeruginosa Type III Secreted Proteins.- Cell Fractionation.- Characterization of Molecular Interactions using Isothermal Titration Calorimetry.- Proteomic Analysis.- Membrane Proteomics of Pseudomonas aeruginosa.- Con-struction of Pseudomonas Two-hybrid Libraries for High-throughput Assays.- Biosensors for Qualitative and Semi-quantitative Analysis of Quorum Sensing Signal Molecules.- LC-MS/MS Quantitative Analysis of Quorum Sensing Signal Molecules.- LC/MS/MS-Based Quantita-tive Assay for the Secondary Messenger Molecule, c-di-GMP.- Metabolic Footprinting: Extracellular Metabolomic Analysis.- Pyoverdine and Pyochelin Measurements.- Measurement of Phenazines in Bacterial Cultures.- Extraction and Measurement of NAD(P)+ and NAD(P)H.- Cyanide Measure-ments in Bacterial Culture and Sputum.- Monitor-ing Iron Uptake by Siderophores. [...]

Fields of interestMicrobiology; Bacteriology



Due October 2014

2015. XV, 900 p. 150 illus., 83 in color. (Methods in Molecular Biology, Volume 1149) Hardcover7 * € (D) 149,79 | € (A) 153,99 | sFr 186,507 € 139,99 | £126.00ISBN 978-1-4939-0472-3

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D. Fleury, R. Whitford, University of Adelaide Waite Research Institute, Urrbrae, SA, Australia (Eds)

Crop BreedingMethods and Protocols

Features 7 Includes cutting-edge methods and proto-cols 7 Provides step-by-step detail essential for reproducible results 7 Contains key notes and implementation advice from the experts

Contents Defining a Genetic Ideotype for Crop Improve-ment.- From Genes to Markers: Exploiting Gene Sequence Information to Develop Tools for Plant Breeding.- Temperature Switch PCR (TSP) – A Gel-Based Molecular Marker Technique for Investigating Single Nucleotide Polymorphisms.- Multiplex-Ready Technology for Mid-Throughput Genotyping of Molecular Markers.- Genotyping by High-Resolution Melting Analysis.- Bi-Allelic SNP Genotyping Using the TaqMan® Assay.- SNP Genotyping: The KASPTM Assay.- Rindsel: An R Package for Phenotypic and Molecular Selec-tion Indices Used in Plant Breeding.- OptiMAS: A Decision Support Tool to Conduct Marker-Assisted Selection Programs.- Genomic Selec-tion in Plant Breeding.- Simulated Breeding with QU-GENE Graphical User Interface.- The Control of Recombination in Wheat by Ph1 and Its Use in Breeding.- TILLING for Plant Breeding.- In vitro Culture for Doubled Haploids: Tools for Molecular Breeding.- Biolistic Transformation of Wheat with Centrophenoxine as a Synthetic Auxin.- Agro-bacterium-Mediated Transformation of Barley (Hordeum vulgare L.).- qPCR for Quantification of Transgene Expression and Determination of Transgene Copy Number.- High-Throughput Analysis Pipeline for Achieving Simple Low-Copy Wheat and Barley Transgenics.

Fields of interestPlant Sciences; Plant Genetics & Genomics



Due April 2014

2014. XVI, 264 p. 67 illus., 58 in color. (Methods in Molecular Biology, Volume 1145) Hardcover7 * € (D) 101,64 | € (A) 104,49 | sFr 126,507 € 94,99 | £85.50ISBN 978-1-4939-0445-7

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Y. Fujiyoshi, Cellular and Structural Physiology Inst. Nagoya University, Nagoya, Japan

Structural Biology of MembranesThe volume describes the three-dimensional structural features of the molecules underlying the physiologic functions of biologic membranes. While this book has a rather clear focus on the membrane, as a major component of any cell, it will also cover the other crucially important functions within cells, further enhancing and deepening the understanding of biologic function. This knowledge is believed to be vital in the devel-opment of new pharmaceutical modalities, given that almost 50% of drug targets are thought to be membrane proteins. This book is designed to be a reference text for a broad range of readers, from researchers in a variety of scientific and related medical fields, to graduate students working in these specialties.

Fields of interestProtein Structure; Membrane Biology; Biochem-istry, general


Product categoryMonograph

Due June 2015

2015. XVIII, 470 p. 100 illus. in color. Hardcover7 approx. * € (D) 160,45 | € (A) 164,94 | sFr 200,007 approx. € 149,95 | £135.00ISBN 978-4-431-54131-8

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Z. He, USDA-ARS, New Orleans, LA, USA; H. Zhang, Oklahoma State University, Stillwater, OK, USA (Eds)

Applied Manure and Nutrient Chemistry for Sustainable Agriculture and EnvironmentContents Preface.- About the editors.- 1 Animal Manure Production and Utilization in the US.- 2 Residual Veterinary Pharmaceuticals in Animal Manures and Their Environmental Behaviors in Soils.- 3 Changes in Nutrient Content and Availability dur-ing the Slow Pyrolysis of Animal Wastes.- 4 Soil Amino Compound and Carbohydrate Contents Influenced by Organic Amendments.- 5 Nitrogen Mineralization in Soils Amended with Manure as Affected by Environmental Conditions.- Soil Enzyme Activities as Affected by Manure Types, Application Rates, and Management Practices.- 7 Phosphatase Activities and Their Effects on Phosphorus Availability in Soils Amended with Livestock Manures.- 8 Variety and Solubility of Phosphorus Forms in Animal Manure and Their Effects on Soil Test Phosphorus.- 9 Phytate in Animal Manure and Soils: Abundance, Cycling and Bioavailability.- 10 Phosphorus Forms and Mineralization Potentials of Alabama Upland Cotton Production Soils Amended with Poultry Litter.- 11 Chemistry and Application of Industrial By-Products to Animal Manure for Reducing Phosphorus Losses to Surface Waters.- 12 Nutrient Chemistry of Manure and Manure-Impacted Soils as Influenced by Application of Bauxite.- 13 Inves-tigation of Compound-Specific Organic-Inorganic Phosphorus Transformation Using Stable Isotope Ratios in Phosphate.- 14 Chemical Characteristics of Custom Compost for Highbush Blueberry. [...]

Fields of interestLife Sciences, general; Agriculture; Sustainable Development



Due May 2014

2014. III, 372 p. 101 illus., 39 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-017-8806-9

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H. Hepburn, Rhodes University, Grahamstown, South Africa; C. Pirk, University of Pretoria, Pretoria, South Africa; O. Duangphakdee, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand

Honeybee NestsComposition, Structure, Function

This work, a sequel to Honeybees and Wax published nearly 30 years ago, starts with a brief introduction and discussion of nesting sites, their spaces and densities, self-organization of nest contents, and interspecific utilization of beeswax. The following chapters cover communication by vibrations and scents and wax secretion, and discuss the queen in relation to the combs.

Features 7 Includes recent findings in the fields of materi-als sciences, structural engineering, molecular biology, polymer chemistry, and biomimet-ics 7 Written by experts in the field 7 Richly illustrated

Contents General Introduction.- Nesting: Sites, Space and Density in Comb-building.- Self-organization of Nest Contents.- Intraspecific and Interspecific Comb-building.- Communication by Vibrations and Scents in Comb.- Wax Secretion, Comb Construction and the Queen.- The Significance of Brood.- The Role of Pollen in Honeybee Colonies.- Nectar Flows and Comb-building.- Construction of Combs.- Energetics of Honey/Beeswax Conver-sion.- Construction of Cells.- Conversion of Wax Scales into Comb Wax.- Material Properties of Scale and Comb Wax.- The Wax Gland Com-plex.- The Chemistry of Beeswax.- Synthesis of Beeswax.- Material Properties of Honeybee Silk.

Fields of interestEntomology; Biophysics and Biological Physics; Biomaterials



Due May 2014

2014. XVI, 389 p. 171 illus., 100 in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-3-642-54327-2

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M. F. Hohmann‑Marriott, Norwegian University of Science and Technology, Trondheim, Norway (Ed)

The Structural Basis of Biological Energy GenerationContents From the Series Editors.- The Series Editors.- Pref-ace.- The Editor.- Contributors.- Author Index.- 1. Proton-Pumping Microbial Rhodopsins – Ubiq-uitous Structurally Simple Helpers of Respira-tion and Photosynthesis; Leonid S. Brown.- 2. Structure and Functional Heterogeneity of Fucoxanthin-Chlorophyll Proteins in Diatoms; Kathi Gundermann, Claudia Büchel.- 3. Structure-Function Relationship in Peridinin-Chlorophyll Proteins; Tomáš Polívka, Eckhard Hofmann.- 4. Piecing Together the Phycobilisome; Ailie Marx et al.- 5. Chlorosomes: Structure, Function and Assembly; Jakub Psencik et al.- 6. The Structure of ATPsynthases in Photosynthesis and Respiration; Bettina Böttcher, Peter Gräber.- 7. Carboxysomes – Sequestering RubisCO for Efficient Carbon Fixa-tion; Matthew S. Kimber.- 8. Rieske/Cytochrome b Complexes: The Turbo Chargers of Chemiosmo-sis; Felix ten Brink, Frauke Baymann.- 9. Quinol Oxidases; Allison E. McDonald, Greg C. Vanler-berghe.- 10. Probing the Action of Cytochrome c Oxidase; Vangelis Daskalakis, Constantinos Varot-sis.- 11. Evolution of Structural and Coordination Features within Methionine Sulfoxide Reductase B Family; Elena Shumilina et al.- 12. Respiratory Chain Supercomplexes in Mitochondria; Natalya V. Dudkina et al.- 13. Energy Conservation in Heliobacteria: Photosynthesis and Central Carbon Metabolism; W. Matthew Sattley et al.- 14. The Architecture of Cyanobacteria, Archetypes of Mi-crobial Innovation; Claire S. Ting.- 15. Respiration and Oxidative Phosphorylation in Mycobacteria; Michael Berney, Gregory M. Cook. [...]

Fields of interestLife Sciences, general; Cell Physiology; Biochem-istry, general



Due May 2014

2014. XV, 475 p. 185 illus., 131 in color. (Advances in Photosynthesis and Respiration, Volume 39) Hardcover7 * € (D) 223,63 | € (A) 229,90 | sFr 278,507 € 209,00 | £188.50ISBN 978-94-017-8741-3

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B. L. Kidder, National Heart, Lung, and Blood Institute, Bethesda, MD, USA (Ed)

Stem Cell Transcriptional NetworksMethods and Protocols

Contents Efficient Library Preparation for Next-Generation Sequencing Analysis of Genome-Wide Epigen-etic and Transcriptional Landscapes in Embry-onic Stem Cells.- Analysis of Next-Generation Sequencing Data Using Galaxy.- edgeR for Differential RNA-seq and ChIP-seq Analysis: An Application to Stem Cell Biology.- Use Model-based Analysis of ChIP-Seq (MACS) to Analyze Short Reads Generated by Sequencing Protein-DNA Interactions in Embryonic Stem Cells.- Spa-tial Clustering for Identification of ChIP-Enriched Regions (SICER) to Map Regions of Histone Methylation Patterns in Embryonic Stem Cells.- Identifying Stem Cell Gene Expression Patterns and Phenotypic Networks with AutoSOME.- Vi-sualization and Clustering of High-Dimensional Transcriptome Data Using GATE.- Interpreting and Visualizing ChIP-seq Data with the seqMIN-ER Software.- A Description of the Molecular Signatures Database (MSigDB) Website.- Use of Genome-Wide RNAi Screens to Identify Regula-tors of Embryonic Stem Cell Self-Renewal and Pluripotency.- Correlating Histone Modifica-tion Patterns with Gene Expression Data During Hematopoiesis.- In Vitro Maturation and In Vitro Fertilization of Mouse Oocytes and Preimplanta-tion Embryo Culture.- Derivation and Manipu-lation of Trophoblast Stem Cells from Mouse Blastocysts.- Conversion of Epiblast Stem Cells to Embryonic Stem Cells Using Growth Factors and Small Molecule Inhibitors.- Generation of Induced Pluripotent Stem Cells Using Chemical Inhibition and Three Transcription Factors. [...]

Fields of interestCell Biology; Stem Cells



Due April 2014


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96


T. K. Lim, Canberra, ACT, Australia

Edible Medicinal And Non Medicinal PlantsVolume 8, Flowers

Volume 8 is part of a multicompendium Edible Medicinal and Non-Medicinal Plants, on plants with edible flowers from Geraniaceae to Zingib-eraceae (tabular) and 82 species in Geraniaceae, Iridaceae, Lamiaceae, Liliaceae, Limnocharitaceae, Magnoliaceae, Malvaceae, Meliaceae, Myrtaceae, Nyctaginaceae, Nymphaeaceae, Oleaceae, Ona-graceae, Orchidaceae, Paeoniaceae, Papaveraceae, Plantaginaceae, Poaceae, Polygonaceae, Primula-ceae, Proteaceae, Ranunculaceae, Rosaceae, Rubia-ceae, Rutaceae, Solanaceae, Theaceae, Tropaeola-ceae, Tyhpaceae, Violaceae, Xanthorrhoeaceae and Zingiberaceae in detail.

Features 7 200 - 400 coloured illustrations per vol-ume 7 Referenced up-to-date-information on nutritive and medicinal properties 7 Common and vernacular names to help in plant identifica-tion 7 Medical and scientific glossaries

Contents Introduction.- Geraniaceae.- Irida-ceae.- Lamiaceae.- Liliaceae.- Limno-charitaceae.- Limnocharis flava.- Magno-liaceae.- Malvaceae.- Meliaceae.- Azadirachta indica.- Myrtaceae.- Nyctaginaceae.- Nympha-eaceae.- Oleaceae.- Onagraceae.- Orchidaceae.- Paeoniaceae.- Papaveraceae.- Plantaginaceae.- Poaceae.- Polygonaceae.- Primulaceae.- Prote-aceae.- Ranunculaceae.- Rosaceae.- Rubiaceae.- Rutaceae.- Solanaceae.- Theaceae.- Tropaeola-ceae.- Typhaceae.- Violaceae.- Xanthorrhoe-aceae.- Zingiberaceae.- Author’s Blurb.- Medical Glossary.- Scientific Glossary.- Common Name Index.- Scientific Name Index.

Fields of interestPlant Sciences; Agriculture; Nutrition



Due April 2014

2014. X, 717 p. 281 illus. in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-017-8747-5

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A. Morte, Universidad de Murcia, Murcia, Spain; A. Varma, Amity University Uttar Pradesh, Noida, India (Eds)

Root EngineeringBasic and Applied Concepts

This volume illustrates the complex root system, including the various essential roles of roots as well as their interaction with diverse microorgan-isms localized in or near the root system. Follow-ing initial chapters describing the anatomy and ar-chitecture as well as the growth and development of root systems, subsequent chapters focus on the various types of root symbiosis with bacteria and fungi in the rhizosphere. A third section covers the physiological strategies of roots, such as nitrate assimilation, aquaporins, the role of roots in plant defense responses and in response to droughts and salinity changes. The book’s final chapters discuss the prospects of applied engineering of roots, i.e., inventing new root structures or func-tions through genetic modification, but also with conventional breeding and manipulation of root symbionts. The budding field of root engineering is expected to promote a second green revolution.

Features 7 A valuable source of information for scientists in soil ecology, agriculture, plant sciences and microbiology 7 Provides basic research results as well as practical applications 7 With contribu-tions by internationally recognized scientists

Contents Parts: Anatomical and Morphological Strategies of Roots.- Rhizosphere and Microorganisms.- Physi-ological Strategies of Roots.- Applied Engineering of Roots.

Fields of interestAgriculture; Microbiology; Plant Physiology



Due May 2014

2014. X, 513 p. 82 illus., 40 in color. (Soil Biology, Volume 40) Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-3-642-54275-6

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S. Paillard, INRA, Paris, France; S. Treyer, IDDRI, Paris, France; B. Dorin, CIRAD, Montpellier, France (Eds)

Agrimonde – Scenarios and Challenges for Feeding the World in 2050Contents Preface.- Agrimonde: a work collective.- Ac-knowledgments.- Introduction.- 1 Agrimonde: a platform for facilitating collective scenario-build-ing.- 2 Agribiom: a tool for scenario-building and hybrid modelling.- 3 The world food economy: a retrospective overview.- 4 Scenario-building choices and principles.- 5 Food consumption in 2050.- 6 Land use in 2050.- 7 Food crop yields in 2050.- 8 Resource-use balances in the Agrimonde scenarios.- 9 Agrimonde 1 and Agrimonde GO: comparison, coherence, drivers of change.- 10 Qualitative dimensions and Agrimonde scenario storylines.- 11 Scenario-based insight into food behaviours, technological options and trade :Food behaviours in question: are ruptures plausible?.- Conclusion.- Appendices.- Appendix 1 – Lists of countries and FAO-SUA product lines used in Agribiom – Comparison of observed and simulated animal food Productions.- Appendix 2 – Review of the world food economy.- Appendix 3 – Food availability and loss of food calories in the Agrimonde GO scenario – Definition of loss and waste of food calories.- Appendix 4 – Land areas in Agrimonde GO.- Appendix 5 – Main quantita-tive assumptions of Agrimonde scenarios – Pro-cess for attaining a resource-use balance.- Appen-dix 6 – Assumptions on the qualitative dimensions of the Agrimonde scenarios.- References.- List of abbreviations and acronyms.- List of authors.

Fields of interestAgriculture; Sustainable Development; Agricul-tural Economics



Due April 2014

Jointly published with Éditions Quæ, R10,78026 Versailles cedex, France

2014. I, 295 p. 114 illus. in color. Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-017-8744-4

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97


E. Palmer, Imperial College London MRC Clinical Sciences Centre, London, UK

Cell-Based MicroarraysReview of Applications, Developments and Technological Advances

This book is a review on the evolution of cell-based microarrays and an update to the author’s earlier book Methods in Molecular Biology: Cell-Based Microarrays. Since their development in 2001, cell-based microarrays have advanced significantly to include expression arrays, short interfering RNA arrays and antibody arrays. The surface used to coat the glass slides has also been significantly improved to allow non-adherent cells to bind to the arrays.

Features 7 Explores the evolution of cell-based microar-rays 7 Reviews and updates four key aspects of cell-based microarrays 7 Updates the earlier work Methods in Molecular Biology: Cell-Based Microarrays

Contents 1 Cell-based microarrays: recent advances for gene function analyses.- 2 Review of siRNA/shRNA Applications in Cell-Based Microarrays.- 3 Anti-body microarrays for cell-based assays: The use of micro-arrayed antibodies for exploring cell surface diversity or whole cell functionality.- 4 Polymer microarrays for high throughput biomaterials discovery.- 5 Microfluidics cell-based microarray review.

Fields of interestCell Biology; Microarrays; Human Genetics



Due April 2014

2014. X, 80 p. 13 illus., 12 in color. (SpringerBriefs in Cell Biology) Softcover7 * € (D) 53,49 | € (A) 54,99 | sFr 67,007 € 49,99 | £44.99ISBN 978-1-4939-0593-5

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M. Rodríguez‑Concepción, Ctr for Research in Agricultural Genomic (CRAG), Barcelona, Spain (Ed)

Plant IsoprenoidsMethods and Protocols

Contents Plant Isoprenoids: A General Overview.- Mea-suring the Activity of 1-Deoxy-D-Xylulose 5-Phosphate Synthase, the First Enzyme in the MEP Pathway, in Plant Extracts.- Determination of 3-Hydroxy-3-methylglutaryl CoA Reduc-tase Activity in Plants.- Farnesyl Diphosphate Synthase Assay.- Metabolite Profiling of Plastidial Deoxyxylulose-5-Phosphate Pathway Interme-diates by Liquid Chromatography and Mass Spectrometry.- Analysis of Carotenoids and Tocopherols in Plant Matrices and Assessment of Their In Vitro Antioxidant Capacity.- Simultane-ous Analyses of Oxidized and Reduced Forms of Photosynthetic Quinones by High-Performance Liquid Chromatography.- Determination of Sterol Lipids in Plant Tissues by Gas Chromatography and Q-TOF Mass Spectrometry.- Analysis of Plant Polyisoprenoids.- Analysis of Diterpenes and Triterpenes from Plant Foliage and Roots.- Gas Chromatography Mass-Spectrometry Method for Determination of Biogenic Volatile Organic Compounds Emitted by Plants.- Analysis of Steroidal Alkaloids and Saponins in Solanaceae Plant Extracts using UPLC-qTOF Mass Spectrom-etry.- Isoprenoid and Metabolite Profiling of Plant Trichomes.- Sample Preparation for Single Cell Transcriptomics - Essential Oil Glands in Citrus Fruit Peel as an Example.- Prenylquinone Profiling in Whole Leaves and Chloroplast Subfractions.- Confocal Laser Scanning Microscopy Detection of Chlorophylls and Carotenoids in Chloroplasts and Chromoplasts of Tomato Fruit.- Heterologous Expression of Triterpene Biosynthetic Genes in Yeast and Subsequent Metabolite Identification Through GC-MS. [...]

Fields of interestPlant Sciences; Plant Biochemistry



Due May 2014


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V. V. Roshchina, Russian Academy of Sciences, Pushchino, Russia

Model Systems to Study the Excretory Function of Higher PlantsThe secretory activity of plants is a manifestation of the fundamental property of all living organ-isms: the ability to exchange substances and en-ergy with the environment. This book summarizes today’s knowledge of all such secretory activities of higher plants. It equally considers the cellular aspects, intratissular and external secretion, gas excretion and the excretion of substances under extreme conditions as well as the biological effects of plant excreta. The first edition of the book was published in Russian in Moscow in 1989 ( Nauka Publishing House), then the English larger variant – in Heidelberg-Berlin 1993 (Springer-Verlag).

Features 7 Lecture material for courses in Plant Physiol-ogy, Pharmacology and Pharmacognosia, Botany, Biophysics, and Ecology 7 Handbook for Plant Science 7 A modern review unifying main lines of the problem of the plant excretory function

Contents Preface.- Introduction.- 1. Approaches to Choice of Model Systems for Microscopic Studies.- 2. In-tact Secretory Cells as Models – Acceptors Sensi-tive to Secretory Products.- 3. Models – Acceptors of Secretions and their Reactions on Exome-tabolites.- 4. Modeling of Cell-Cell Contacts.- 5. Application of Models in Pharmacology, Medicine and Ecology.- Conclusion.- References.- Subject Index.- Latin Index.

Fields of interestPlant Physiology; Plant Ecology; Plant Sciences



Due July 2014

the first edition of the book was published in Russian in Moscow in 1989 ( Nauka Publishing House). An English larger variant – in Heidelberg-Berlin 1993 (Springer-Verlag).

2014. Approx. 200 p. 55 illus., 24 in color. Hardcover7 approx. * € (D) 160,45 | € (A) 164,94 | sFr 200,007 approx. € 149,95 | £135.00ISBN 978-94-017-8785-7

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98


S. Weber, E. Schleicher, Albert-Ludwigs-Universität Freiburg, , Germany (Eds)

Flavins and FlavoproteinsMethods and Protocols

In Flavins and Flavoproteins: Methods and Pro-tocols, expert researchers in the field detail many of the methods which are now commonly used to study flavins and flavoproteins. These include review style methods and protocols to exemplify the variety, the power and the success of modern techniques and methods in application to flavo-proteins.

Features 7 Presents current up-to-date methodolo-gies 7 Provides step-by-step detail essential for reproducible results 7 Contains key notes and implementation advice from the experts

Contents Structure and General Properties of Flavins.- Re-cent advances in Riboflavin Biosynthesis.- Natural Riboflavin Analogs.- A Roadmap to the Isotopolog Space of Flavocoenzymes.- Electron Transferases.- Aldonolactone Oxidoreductases.- Flavins and Flavoproteins: Applications in Medicine.- Practical Aspects on the Use of Kinetic Isotope Effects as Probes of Flavoprotein Enzyme Mechanisms.- On the in vivo Redox State of Flavin-Containing Photosensory Receptor Proteins.- Computational Spectroscopy, Dynamics and Photochemistry of Photosensory Flavoproteins.- NMR Spectroscopy on Flavins and Flavoproteins.- Solid-State NMR of Flavins and Flavoproteins.- EPR on Flavopro-teins.- FTIR Spectroscopy of Flavin-Binding Pho-toreceptors.- Resonance Raman Spectroscopy.- Photoactivation Mechanisms of Flavin-binding Photoreceptors Revealed through Ultrafast Spec-troscopy and Global Analysis Methods.- Excited State Chemistry of Flavoproteins.

Field of interestProtein Science



Due April 2014

2014. XII, 520 p. 128 illus., 69 in color. (Methods in Molecular Biology, Volume 1146) Hardcover7 * € (D) 117,69 | € (A) 120,99 | sFr 146,507 € 109,99 | £99.00ISBN 978-1-4939-0451-8

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K.‑Q. Zhang, Yunnan University, Kunming, People’s Republic of China; K. D. Hyde, Mae Fah Luang University, Chiang Rai, Thailand (Eds)

Nematode-Trapping FungiThese chapters provide up-to-date information on nematophagous fungi, particularly those of the Orbiliaceae in Ascomycota, whose asexual states produce nematode-trapping devices. The authors consider fungal-nematode interactions, fossil fungi, the biodiversity, ecology and geographi-cal distribution of nematode-trapping fungi, and their potential use in biocontrol of nematodes, all in detail. Nematode-trapping fungi with adhesive or mechanical hyphal traps are the main focus of this book which begins with an overview of the data on nematode-trapping fungi, including their taxonomy, phylogeny and evolution. Subsequent chapters expand upon the methods and tech-niques used to study these fascinating fungi.

Features 7 Collates and presents data on nematode-trapping fungi and describes their ecology 7 Ex-amines the use of nematode-trapping fungi in biological control 7 Explores the mechanisms involved in nematicidal activities and considers how these can be further explored

Contents Preface.- Abstract.- 1. Nematode-Trapping Fungi.- 2. Methodology for Studying Nematophagous Fungi.- 3. Taxonomy of Nematode-Trapping Fungi from Orbiliaceae, Ascomycota.- 4. The Ecology of Nematophagous Fungi in Natural Environments.- 5. Biological Control of Plant-Parasitic Nema-todes by Nematophagous Fungi.- 6. Molecular Mechanism of Nematophagous Fungi Infection of Nematodes.- 7. Nematode-Toxic Fungi and their Nematicidal Metabolites.- 8. Future Study.- Index.

Fields of interestFungus Genetics; Evolutionary Biology; Ecotoxi-cology



Due April 2014

2014. I, 325 p. 137 illus., 14 in color. (Fungal Diversity Research Series, Volume 23) Hardcover7 * € (D) 160,49 | € (A) 164,99 | sFr 200,007 € 149,99 | £135.00ISBN 978-94-017-8729-1

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X. Zhao, Institute of Zoology Chinese Academy of Science, Beijing, China

Studies of pluripotency in embryonic stem cells and induced pluripotent stem cellsStem cells have the ability to differentiate into all types of cells within the body, thus have great ther-apeutic potential for regenerative medicine to treat complicated disorders, like Parkinson’s disease and spinal cord injury. There will also be many ap-plications in drug development. However, several roadblocks, such as safety issues and low efficiency of pluripotent stem cell (PSC) line derivation need to be resolved before their clinical application. This thesis focuses on these two areas, so as to find methods to overcome the limitation. It covers deriving embryonic stem cells (ESCs) from several different species and reports an efficient system to generate induced pluripotent stem cells (iPSCs), and the first iPSC mice in the world.

Features 7 Nominated as an outstanding Ph.D. thesis by Chinese Academy of Sciences, China 7 Cover-ing methods to derive embryonic stem cells from various species 7 Designing an efficient system to generate induced pluripotent stem cells 7 Re-porting the first iPS mice in the world

Contents Abstract.- Introduction.- Establishment of highly efficient somatic cell reprogramming system to generate iPSC lines- Establishment of highly efficient somatic cell reprogramming system and establishment of iPSC lines.- Pluripotency of iPSC and underlining mechanism.- Developmental potential of mouse iPSC.- Conclusions.

Fields of interestStem Cells; Cell Culture; Regenerative Medicine/Tissue Engineering


Product categoryPh.D. Thesis

Due April 2014

2014. Approx. 100 p. 21 illus., 15 in color. (Springer Theses) Hardcover7 * € (D) 85,59 | € (A) 87,99 | sFr 106,507 € 79,99 | £72.00ISBN 978-94-017-8818-2

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