st sement elevation myocardial infarction (stemi)

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    ST SEGMENT ELEVATION MYOCARDIALINFARCTION (STEMI)I N F E R I O R O N S E T > 2 4 H O U R S , K I L L I P 1 , T I M IS C O R E 2 / 1 4 ( 2 , 2 % )

    PRESENTED BY : NUR HALIMATUSSANIAHC111 09 849

    SUPERVISED BY : DR PENDRIK TANDEAN, Sp PD-KKV, FINASIM

    KEPANITERAAN KLINIK BAGIANKARDIOVAKULER

    UNIVERSITAS HASANUDDINMAKASSAR

    2013

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    PATIENT IDENTITY

    MR number : 636103

    NAME : MR A

    AGE : 47 years old

    DATE OF ADMISSION: 7 TH November 2013

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    HISTORY TAKING

    Chief complaint: Chest pain

    Occurred 3 days before admitted,At the beginning, the chestpain was like being sliced, burned, the painwas radiated from the chest till the jaw

    The pain occur while the patient carry boxes of paper.

    Duration of chest pain is about an hour and did not relieved by rest.

    Patient have been admitted in RS Pare-pare before he been refferred toRSWS.

    Shortness of breath (-) , sweating (+), weakness (-), and nausea (-),Cough (-), fever (-)

    Proxymal Nocturnal Dyspneu (-), Dyspneu On Effort (+), Ortopneu (-)Defecation and urination : normal

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    HISTORY OF PAST ILLNESS

    History of hypertension ( + ) since 3 years ago with uncontrolled

    therapy

    History of Osteorthritis (+) 2 years ago

    History of diabetes mellitus (-)

    History of family with CVD ( - )

    History of smoking (+) 1 year ago, 2 packet daily

    History of heart disease (-)History of family with heart disease (-)

    History of asthma (-)

    History of gastritis (-)

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    RISK FACTORS

    Modifiable

    - Hypertension (+)- Tobacco use (+)

    NonModifiable

    Gender :Male

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    PHYSICAL EXAMINATION

    General status Moderate

    illness/wellnourished/conscious

    Vital sign BP: 170 / 90 mmHg

    HR: 70 x/min RR: 18 x/min

    T : 36.5 0 C

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    REGIONAL STATUS

    Head ExaminationEyes : anemia (-), icterus (-)Lip : cyanosis (-)

    Neck : lymphadenopathy (-), JVP R +0 cmH2O

    Thoracal ExaminationInspection : symetric, normochestPalpation : mass (-), tenderness (-), VF R=LPercussion : sonor

    Auscultation : breath sound : bronchovesicular,ronchi -/-, wheezing -/-

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    REGIONAL STATUS

    Heart ExaminationInspection : IC wasnt visible Palpation : IC wasnt

    palpablePercussion : normal heartsizeUpper border : left 2 nd ICSLower border : left 5 th ICSRight border : right

    parasternalis lineLeft border : leftmedioclavicular lineAuscultation : Regular of I/IIheart sound, murmur (-)

    Abdominal ExaminationInspection : flat andfollowing breath movementAuscultation : peristaltic sound(+) , normalPalpation : liver and spleenunpalpablePercussion : tympani, ascites(-)

    ExtremitiesOedema : pretibial (-),dorsum pedis (-)

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    INTERPRET TION

    Rhythm : SinusHeart rate : 56 bpmRegularity : regulerAxis : Normoaxis, 20 o

    QRS duration : 0.92 sPR interval : 0.12sP wave : 1.08sST Segment : T inverted at lead II,III,AVFConclusion : Possible Inferiormyocardial infarction, probably oldsummary

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    ECHOCARDIOGRAPHY 7/11/2013

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    DESCRIPTION OF WALL MOTION, MASSES,VALVES, PERICARDIUM- LV systolic function, EF 67%

    - Dimension of Cardiac compartment : normal- LVH: (-)- Hipokinetic of inferior base + inferoseptl- RV systolic function is good, TAPSE : 1.8cm

    - Cardiac valve :- Mitral : function and movement good- Aorta : 3 cuspis, calcification (-), function &

    movement normal- Tricuspid : function & movement normal- Pulmonal :function & movement normal

    - E/A > 1 (Pseudonormal)

    - Conclusion :LV diastolic dysfunction, EF 67%, Hipokinetic of inferior base + inferoseptl e.cCAD

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    L BOR TORY EX MIN TION

    C o m p

    l e t e b l o o d

    WBC : 8.11 x 10 3 HGB : 14.3 g/dlHCT : 42.9 %RBC : 4.73 x 106 /mm 3

    PLT : 247x 10 3 /mm 3 Cardiac enzyme

    CK : 1393 u/L CK MB : 19 u/L Troponin T : 0,33 u/LElectrolyte

    Sodium :143 mmol/lPotassium : 4.4 mmol/lChloride : 108 mmol/l

    B l o o d c h e m

    i s t r y

    Random blood sugar: 106 mg/dlSGOT : 71 u/lSGPT : 35 u/lUreum : 28Creatinin : 0.7PT : 9,9APTT : 24,4Total Cholesterol : 212mg/dlHDL : 35 mg/dlLDL : 176 mg/dlTriglyseride : 187 mg/dl

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    WORKING DIAGNOSISSTEMI Inferior onset 1 hour,

    KILLIP I

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    MANAGEMENT

    O 2 2 LPM (via nasal canule)

    Cardiac Diet

    IVFD NaCl 0,9% loading 500 cc/24 hoursVasodilator

    Cedocard 0.5mg/hour via SP

    Anti Platelet AggregationASA (Aspilet) 2 x 80 mg

    Clopidogrel (Plavix) 4 x 75 mgACEI

    Captopril 3 x 12,5mg

    Anti cholesterolHMG-Co A reductase inhibitor (Simvastatin 1 x 20 mg)

    AnxiolyticBenzodiazepin (Alprazolam) 0,5 mg 0- 0 - 1

    LaxativeLaxadin syrup 1 x 2 cth

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    ACUTE CORONARY SYNDROMEST SEGMENT ELEVATIONMYOCARDIAL INFARCTION

    D I SCU SSI O N

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    DEFINITION

    - Acute coronary syndrome (ACS) covers a range of

    disorders including myocardial infarction (heartattack) and unstable angina that are caused by the

    same underlying problem.

    - The underlying problem is a sudden reduction of

    blood flow to part of the heart muscle. This is usually

    caused by a blood clot that forms on a patch ofatheroma within a coronary artery (which is

    described below).

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    DIAGNOSIS OF ACS

    Ischemic symptoms Prolonged pain

    (usually >20 mins) constricting,crushing, squeezing

    Usually retrosternal

    location, radiating toleft chest, left arm;can be epigastric

    Dyspnea Diaphoresis Palpitations Nausea/vomiting Light headedness Sense of impending

    doom

    DiagnosticECGchanges

    Serum cardiacmarkerelevations

    TroponinT CK-MB

    CK Myoglobin

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    LOCATION OF CHEST PAIN DURING HEART ATTACK

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    SERUM CARDIAC BIOMARKERS

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    RISK FACTOR FOR ACS

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    PROGNOSIS BASED ON KILLIP CLASSIFICATION

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    INITIAL TREATMENT

    Fixing the chest pain and fearness

    Bed rest Diet O 2 2-4 lpm via nasal prongs or face mask Sublingual/oral/IV nitroglycerine Antiplatelet: aspirin and clopidogrel Morfin/petidine Diazepam 2-5mg/8 hour

    Stabilizing the hemodynamic (blood pressure and peripheralpulse control)

    -blocker if there is no contraindication Calcium channel blocker (CCB) ACE-Inhibitor

    Reperfusion of the myocard

    Thrombolytic

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    COMPLICATIONS

    Arrythmia Heart failure Cardiogenic shock

    Rupture ofventricle

    septum/wall

    Rupture ofchordae tendineae Pericarditis

    Tromboemboli

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    SECONDARY PREVENTION Smoking cessation

    Blood pressure control (less than

    140/90 mm Hg, or less than 130/80

    mm Hg in patients with diabetes or

    chronic kidney disease)

    Lipid management (LDL-C level

    substantially less than 100 mg per

    dL; non HDL-C level less than 130

    mg per dL in patients with

    triglyceride levels 200 mg per dL or

    greater)

    Physical activity (30 minutes at least

    five days per week)

    Weight management (BMI 18.5 to

    24.9 kg per m 2; waist circumference

    less than 40 inches in men, less

    than 35 inches in women)

    Diabetes management (A1C less

    than 7 percent)

    Antiplatelet and anticoagulant

    therapy

    Renin-angiotensin-aldosterone

    system blocker therapy