section 4 nervous and endocrine system
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SVQ Level 3SVQ Level 3Instructing Physical ActivityInstructing Physical Activity
& Exercise& Exercise
Dr Sarah J Ramminger
Angus College
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Section 4Section 4 ²² Nervous andNervous and
Endocrine systemEndocrine system
y Role of the Nervous systemy Anatomy and organisation
of the nervous systemy The Motor unity Neuromuscular junction ² a closer looky Endocrine anatomyy Glands and hormonesy Hormones and their role during exercise
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Section 4Section 4 ²² The Nervous systemThe Nervous system
The nervous system of theThe nervous system of thehuman body is responsiblehuman body is responsiblefor sending, receiving andfor sending, receiving andprocessing nerve signalsprocessing nerve signals
throughout the bodythroughout the body
All of the muscles andAll of the muscles andorgans in your body rely onorgans in your body rely on
these signals from thethese signals from thenervous system to work.nervous system to work.
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Sensory inputSensory inputSensory receptors
monitor externaland internal stimulie.g. Touch, temp,
taste, smell, sound
IntegrationIntegrationProcessingProcessing
informationinformation ²² mainmainorgans involved areorgans involved are
spinal chord andspinal chord andbrainbrain
HomeostasisHomeostasisMaintenance of aMaintenance of a
stable internalstable internalenvironmentenvironment
Mental ActivityMental ActivityConsciousness,Consciousness,
thinking, memorythinking, memoryand emotionsand emotions
Control of muscular tissueControl of muscular tissueand glandsand glands
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AnatomyAnatomyof theof theNervousNervoussystemsystem
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Nerve cellsNerve cells
The nervousThe nervoussystem is made upsystem is made upofof specialisedspecialised cellscells
called neurons.called neurons.
The human brainThe human brainhas about 100has about 100
billion neurons.billion neurons.
AxonAxon
DendriteDendrite MyelinMyelinsheathsheath
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The Autonomic Nervous SystemThe Autonomic Nervous System
SympatheticSympatheticnervousnervoussystemsystem
arasympatheticarasympatheticnervousnervoussystemsystem
EntericEntericnervousnervoussystemsystem
Aids in the control of the internal organsAids in the control of the internal organsThree divisionsThree divisions
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The sympathetic nervous system is programmed toprepare the body for stress or a ´fight or flightµ
situation. It is however, always active under basalconditions helping to maintain homeostasis.
The parasympathetic nervous system however,controls maintenance activities and helps conserve thebody·s energy.
Sympathetic and arasympatheticSympathetic and arasympathetic
nervous systemnervous system
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Parasympathetic S ympatheticS ympathetic ganglia
Cervical
Thoracic
Lumbar
Constricts pupil Dilates pupil
Stimulates salivation Inhibits salivation
Inhibits heartactivity
Stimulatesheart activity
Constricts thebronchi
Dilates thebronchi
Stimulatesdigestiveactivity
Inhibits digestive activity
Stimulates gallbladder
Stimulatesglycogenolysis
Contractsbladder
Relaxesbladder
Relaxes rectum Contracts rectum
Stimulates nor /epinephrinerelease from adrenal gland
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Formative task 4.1Formative task 4.1
Research the somatic nervous systemResearch the somatic nervous systemand write a brief overviewand write a brief overview
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ProprioceptionProprioception
ThisThis term refers to the brainsterm refers to the brainsability to sense where ourability to sense where our
body is in space.body is in space.
The brainThe brain gathers and processes a range ofgathers and processes a range of
sensory information from areas such as«sensory information from areas such as«
The vestibular (balance) centre in the inner earThe vestibular (balance) centre in the inner ear
Auditory inputAuditory input
Visual inputVisual input
Sense of smellSense of smell Stretch receptors that monitor length, tension andStretch receptors that monitor length, tension andpressure in our tendons, muscles and ligamentspressure in our tendons, muscles and ligaments
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The Motor UnitThe Motor Unit
The term ´motor unitµ was first introduced byThe term ´motor unitµ was first introduced bySir Charles Sherrington, a pioneer in the fieldSir Charles Sherrington, a pioneer in the field
of neurophysiology.of neurophysiology.
What does a ´mWhat does a ´motorotor unitµ refer to?unitµ refer to?
The term ´motor unitµ refersThe term ´motor unitµ refers to a single motorto a single motorneuroneneurone and all the muscleand all the muscle fibresfibres that it innervates.that it innervates.
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The Motor UnitThe Motor Unit
Motorunit A
Motorunit B
Muscle Musclefibres
Spinal chord
Motor neuroncell body
Motorneuronaxon
Did you know?
One motor neuron can
innervate a number ofmuscle fibres.
A single muscle fibrehowever is suppliedby only one motor
neuron.
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Motor Unit RecruitmentMotor Unit Recruitment
The number ofThe number of fibresfibres contracting within a muscle depends on thecontracting within a muscle depends on thenumber of motor units recruited.number of motor units recruited.
For a weak contraction of the whole muscle, only a few motor unitsFor a weak contraction of the whole muscle, only a few motor unitswill be activated whereas as more motor units are recruited,will be activated whereas as more motor units are recruited,
contractions become stronger and strongercontractions become stronger and stronger
Small or finemanipulations
Majormovements
Motor unitsmay contain asfew as a dozenmuscle fibres
Motor units inthe leg musclesmay contain1500 ² 2000muscle fibres
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Motorunit A
Motorunit B
Muscle Musclefibres
Spinal chord
Motor neuroncell body
Motorneuronaxon
A muscleA muscle fibrefibre atatany given lengthany given lengthwhen stimulated willwhen stimulated willproduce the sameproduce the sameamount of tension.amount of tension.The muscleThe muscle fibrefibre isis
therefore ´Onµ andtherefore ´
Onµ andproducing tension orproducing tension or
´Offµ and resting or´Offµ and resting orrecoveringrecovering
´All or noneµ theory´All or noneµ theory
The theory can beThe theory can beapplied only at theapplied only at themusclemuscle fibrefibre level.level.
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In response to a nerve impulsethe end of the motor nerve fibre
secretes a neurotransmittercalled Ach (acetylcholine)The neurotransmitter (Ach)
travels across the synapse andactivates receptors on the
muscle end plate
This stimulatesa sequence ofevents whichsends a signal
down thetransversetubules which
lead to a releaseof calcium fromthe sarcoplasmicreticulum (SR)
Calcium binds totroponin which
causes aconfimational
shift in positionof tropomysin.
This shiftexposes the
myosin bindingsites on the
actin filament
Cross bridgesare formedbetween the
myosin and actinfilaments. The
energy stored in
the myosin headfrom ATP
breakdown isused for the
´power strokeµ
Calcium ispumped back
into the SR bycalcium pumps.
When thecalcium levellowers myosin
can no longerattach to actinand the muscle
relaxes
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Presynaptic terminal
Ach Vesicles
Sarcolemma Ach Receptors -ligand gated ion
channels
Mitochondria
Sodium pump
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Presynaptic terminal
Ach Vesicles
Sarcolemma Ach Receptors -ligand gated ion
channels
Mitochondrion
Sodium pump
The arrival of an actionpotential at the presynaptic
terminal leads to release ofthe neurotransmitteracetylcholine (Ach)
Ach binds to the ligand gatedion channels which respond by
opening and allowing sodiumions to enter the cell andpotassium ions to leave.
More sodium moves in than potassiumout due to the electrochemicalgradients maintained by the sodiumpump. This causes a depolarisation ofthe membrane which is known as anEnd Plate Potential (EPP)
This depolarisation travelsalong the tranverse tubule and
evokes opening of calciumchannels.
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Section 4Section 4 ²² The Endocrine systemThe Endocrine system
The Endocrine system worksclosely with the nervous systemto regulate bodily functions.
Chemical messengers known ashormones have far reachingeffects controlling processes atevery level, from energy uptake
of a single cell to growth anddevelopment of a body system.
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EndocrineEndocrineAnatomyAnatomy
HypothalamusHypothalamus
Pineal GlandPineal Gland
Pituitary GlandPituitary Gland
Parathyroid GlandsParathyroid Glands
Thyroid GlandsThyroid Glands
ThymusThymus
LiverLiver
Adrenal GlandsAdrenal Glands
KidneyKidney
PancreasPancreas
Ovaries (female)Ovaries (female)
PlacentaPlacenta (during pregnancy)(during pregnancy)
Testes (Male)Testes (Male)
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Gland Hormones produced Target cells
Hypothalamus Releasing and inhibitinghormones such as Growthhormone releasinghormone (GHRH).
Anteriorpituitarygland
Anterior
Pituitary
Thyroid stimulating
hormone
Adrenocorticoidstimulating hormone
Thyroid
gland
Adrenalgland
Pancreas Insulin
Glucagon
Most cells
Most cells
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Gland Hormones produced Target cells
Parathyroid Parathyroid Bones,Kidney,Intestine
Thyroid Thyroid hormone Most cells
Adrenal Epinephrine andNorepinephrine
S ympatheticreceptorsites in thebody
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Glucose metabolismGlucose metabolism
Carbohydrates are the most important short term fuel providers fororganisms since they are more easily metabolised than fats or proteins.
The most important carbohydrate is glucose, asimple monosaccharide..
Stored in the liver and musclein the form of glycogen
A fuel source for glycolysisand the aerobic energy system
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Glucose metabolismGlucose metabolism
Exocrine pancreas
The acini cells secrete
enzymes which aid the
process of digestion
Within the acinar tissuethere are millions of cell
clusters known as ´Islets ofLangerhansµ
Within the ´Islets ofLangerhansµ are two typesof cells. Alpha () and Beta() cells produce the twohormones involved in themetabolism of glucose.
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Glucose metabolismGlucose metabolism
InsulinInsulin
Produced byProduced by cellscells
Promotes uptake ofPromotes uptake of
glucoseglucose into cellsinto cells SpeedsSpeeds up theup the
conversion of glucoseconversion of glucoseinto glycogen for storageinto glycogen for storage
in the liverin the liver
Lowers blood glucoseLowers blood glucose
GlucagonGlucagon
Produced byProduced by cellscells
SpeedsSpeeds up theup the
breakdown of glycogenbreakdown of glycogeninto glucose by the liverinto glucose by the liver
Raises blood glucoseRaises blood glucose
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Formative task 4.2Formative task 4.2
Completing table detailing hormone andCompleting table detailing hormone andprimary actionsprimary actions