SciFinder Scholar

Gary Wigginswiggins@indiana.edu

IU School of Informatics

SciFinder and SciFinder Scholar Includes access to the CA, Registry,

CHEMCATS, CHEMLIST files, plus Medline (1958-)

Easy structure searching capabilities Integrated with ChemPort for easy

access to the primary literature Download page for SFS:

http://www.indiana.edu/~libchem/protected/sciintro.html

Don’t forget the site.prf file!

SciFinder Scholar: IU Options 24-Hour Access Full Substructure Searching Seven Simultaneous Users

License serves all 8 IU campuses

SciFinder Scholar Databases Chemical Abstracts Service Databases

on SFS CAPlus, 1907- Registry File, 1907- CASREACT, 1907- CHEMCATS CHEMLIST

National Library of Medicine Database MEDLINE, 1958-

SciFinder Scholar Content CAPlus

Over 26,000,000 documents as of 12/31/2003

Covers all areas of chemistry: journal articles from more than 8000 journals

Enhanced coverage for 1500 journals since 1994 patents conference proceedings books, dissertations, and technical reports Other types of literature

Relative Contributions of Literature Types to CA

Used with the permission of Chemical Abstracts Service (CAS), a division of the American Chemical Society, from:http://www.cas.org/casdb.html

SciFinder Scholar Content MEDLINE

Over 13 million articles as of 4/3/2003 More than 3900 journals Searched simultaneously with CAPlus Unless turned off:

Results in duplicate answers

CAPlus/MEDLINE Search Options

CAS DBs: Registry File “Authority” file that lets indexers and

searchers definitively identify a substance as new or find a previous entry

Contains all types of chemical substances, including biomolecules

Best file for chemical names Many physical properties being added Linked to CA and other files through the

Registry Number (RN)

Registry File Contents Includes synonyms, molecular

formulas, alloy composition tables, classes for polymers, nucleic acid and protein sequences, ring analysis data, and structure diagrams

Also: experimental and calculated property data from various sources as well as super roles and document type information from CAplus

Size of the Registry FileDate Sunday, 9/26/2004

Count 24,205,177 organic and inorganic substances

48,092,380 sequences

CAS Registry Number 751481-24-0 is the most recent CAS Registry Number

Registry File Enhancements Calculated property values

Number of hydrogen donors Number of hydrogen acceptors Number of rotatable bonds Molecular weight LogD, logP, pKa Solubility in water

Experimental physical properties Only from 1975-1991

Chemical Substance Search

CAS DBs: CASReact Derived from journal and patent

documents from 1840 to date Contains both single-step and multistep

reactions Structure searchable for reagents,

reactants, and products Contains yield data, reaction conditions,

etc. Common functional groups are searchable

CHEMLIST and CHEMCATS Both available in SciFinder Scholar CHEMLIST: Regulated chemicals listing

Chemical substances on national inventories Good for foreign language chemical names

CHEMCATS: commercially available chemicals Includes worldwide suppliers

Links for both included on the Substance Search results record

CAS Databases: Other

MARPAT--more than 500,000 Markush structure records for patents found in the CA File with patent publication year 1988 to the present

TOXCENTER--covers the pharmacological, biochemical, physiological, and toxicological effects of drugs and other chemicals

CAS Roles Used in conjunction with chemical substance searches Seven super roles, e.g., ANST, BIOL, CMBI, FORM,

OCCU, PREP, PROC, RACT, USES Over 60 more specific role descriptors, e.g., with

PREP: BMF Bioindustrial manufacture BPN Biosynthetic preparation BYP Byproduct Combinatorial preparation IMF Industrial manufacture PNU Preparation, unclassified PUR Purification or recovery SPN Synthetic preparation

Also two roles not up-posted to super roles: PRP (Properties) and MSC (Miscellaneous)