rizwan a. manji md phd frcsc mba - umanitoba.ca · rizwan a. manji md phd frcsc mba 2 • cae...
TRANSCRIPT
Rizwan A. Manji MD PhD FRCSC MBA
Curriculum Vitae
Current Position
Cardiac Surgeon/Intensivist
Cardiac Sciences Program
CR3014 – 369 Tache Avenue
Winnipeg, Manitoba, R2H 2A6
Phone: (204) 258-1031
Fax: (204) 231-4624
E-mail: [email protected]
2007 – present: Assistant Professor, Department of Surgery
2012 – present: Assistant Professor, Department of Anesthesia
University of Manitoba
Degrees and Licenses
M.B.A. Masters of Business Administration, University of Manitoba I.H. Asper School of Business,
Winnipeg, Manitoba, Canada – February 2008
F.R.C.P.C. Fellow of the Royal College of Physicians of Canada in Critical Care Medicine, Ottawa,
Ontario, Canada – September 2007
F.R.C.S.C Fellow of the Royal College of Surgeons of Canada in Cardiac Surgery, Ottawa, Ontario,
Canada – June 2005
Ph.D. Doctor of Philosophy in Experimental Surgery, University of Alberta, Edmonton, Alberta,
Canada – November 2001
Licentiate Medical Council of Canada – 1997
M.D. Doctor of Medicine with Distinction and Honours in Research, University of Alberta,
Edmonton, Alberta, Canada – June 1995
B.M.Sc. Bachelor of Medical Science with Distinction, University of Alberta, Edmonton, Alberta,
Canada – November 1993
Other education
• CALS (Cardiac Surgery Advanced Life Support) training course
• TEE training - SCA Atlanta, Georgia
April 25, 2015
May 5-11, 2013
Rizwan A. Manji MD PhD FRCSC MBA
2
• CAE Ultrasound Course – Online Training 2012
• Completion of United States Medical Licensing exam (USMLE) parts
1 and 2
1996
• Advanced Cardiac Life Support, Pediatric Advanced Life Support,
and Advanced Trauma Life Support, Grant MacEwen Community
College and Royal Alexandra Hospital, Edmonton, Alberta,
Canada-
1995
• General Sciences (specialization in Cell Biology), University of
Alberta, Edmonton, Alberta, Canada
1989-1991
Academic Awards
• Archer Daniels Midland Fellowship, I.H. Asper School of Business,
University of Manitoba
Sept. 2006
• First Place Critical Care Medicine In-training exam, University of
Manitoba
Dec. 2005
• Cardiac Surgery First Prize – 97th percentile rank in Cardiac Surgery
in American Association of Thoracic Surgery Exam, University of
Alberta
2005
• Cardiac Surgery First Prize – 93rd
percentile rank in Cardiac Surgery
in the American Association of Thoracic Surgery Exam, University
of Alberta
2004
• Cardiac Surgery First Prize – 96th percentile rank in Cardiac Surgery
in the American Association of Thoracic Surgery Exam, University
of Alberta
2003
• Mosby Book Award – Excellent Academic Standing in Medical
School Class, University of Alberta
1995
• First Prize in Dermatology, University of Alberta 1995
• Aga Khan Foundation Canada Scholarship for Academic Excellence,
University of Alberta
1991-1994
• Nat Christie Foundation Scholarship for Academic Excellence 1993
• Dr. Allan Coates Rankin Prize in Medical Microbiology and
Infectious Diseases
1993
• Louise McKinney Post-Secondary Scholarship, University of Alberta 1992
• Prime Evils Athletic Association Scholarship 1990
Rizwan A. Manji MD PhD FRCSC MBA
3
CLINCIAL
Clinical Work Experience
• Intensivist – Winnipeg Regional Health Authority – Cardiac Surgery
and General Systems
• House Medical Officer – Critical Care Medicine, Grace and
Concordia Hospitals, Winnipeg, Manitoba
2007 - present
2005-2007
• Advanced Cardiac Life Support Medical Director and Instructor –
Grant MacEwan Community College, Edmonton, Alberta
1999-2005
• Advanced Trauma Life Support instructor – Royal Alexandra
Hospital, Edmonton, Alberta
1998-2005
• Basic Trauma Life Support Medical Director and Instructor – Grant
MacEwan Community College, Edmonton, Alberta
1998-2005
RESEARCH
Research Experience
• Outcome Studies in Patients on Extracorporeal Life Support Jun. 2012 - Present
• Rheumatic Heart Disease in Ethiopia – Prevalence Study and Cost-
Effectiveness Study for Prevention of Rheumatic Heart Disease –
Collaborative study with Dr. Julia Witt (Department of Health
Economics, University of Manitoba) and Dr. Richard Northcott
(Canadian Humanitarian Organization for International Relief)
Feb. 2012 - Present
• Gal Knockout Transgenic Pig Valves for Bioprothetic Heart Valve
Replacement – Collaborative study with Dr. Cooper (University of
Pittsburg), Dr. Mohiuddin (National Institutes of Health) and Dr.
David Ayares (Revivicor)
Dec. 2011 - Present
• Outcome Studies in Cardiac Surgery and Cardiac Surgery Critical
Care, University of Manitoba, Winnipeg, Manitoba
Oct. 2007 - Present
• Cardiac Responsiveness to Dobutamine as Predictor of Outcome from
Septic Shock in ICU Patients, University of Manitoba, Winnipeg,
Manitoba
Sept. 2006
• Tolerance Studies in Xenotransplantation in Infants – Collaborative
Study with Dr. David Cooper – Thomas Starzl Transplantation
Institute, University of Pittsburgh Medical Centre, Pittsburgh, PA,
USA
2005 – 2007
Rizwan A. Manji MD PhD FRCSC MBA
4
• Xenoantibodies and Bioprosthetic Cardiac Valve Failure, University
of Alberta, Edmonton, Alberta
2003 - 2007
• Human ABO Blood Group and Anti-a-Gal Antibody Depletion in a
Porcine Human Working Heart Xenotransplantation Model of
Hyperacute Rejection – Ph.D. thesis – University of Alberta,
Edmonton, Alberta
1998 – Nov. 2001
Research Awards
• Citation Finalist - Society of Critical Care Medicine annual meeting
2011 – Abstract: What is the Usefulness of 4T Test and Enzyme
Linked Immunosorbent Assay in Decision Making in Post Cardiac
Surgical ICU Patients Suspected of Heparin Induced
Thrombocytopenia?
Jan 15-19, 2011
• Postgraduate Medical Publication Research Prize – Manuscript:
Glutaraldehyde-Fixed Bioprosthetic Heart Valve Conduits Calcify
and Fail from Xenograft Rejection, University of Alberta
May 2005
• NewEra Cardiac Care Scholarship to attend and present at Innovation
& Technology meeting
Jan. 2005
• George Graham Bursary for Excellence in Resident Research,
University of Alberta
Oct. 2002
• University of Alberta Medical Staff Society Resident Publication
Prize – Manuscript: Human ABO Blood Group is Important in
Survival and Function of Porcine Working Hearts
June 2002
• CIHR Resident Publication Prize – Manuscript Human ABO Blood
Group if Important in Survival and Function of Porcine Working
Hearts, University of Alberta
May 2002
• Finalist in Student Award Competition Canadian Cardiovascular
Congress Meeting, Halifax, Nova Scotia, for abstract: Critical
Factors in Survival of a Pig-Human Xenograft
Oct. 2001
• Nominated for NSERC Doctoral Research Award, Department of
Surgery, University of Alberta
Sept. 2001
• Best Abstract Award (Student - Transplantation) – 6th Symposium of
World Artificial Organ, Immunology, and Transplantation Society,
Ottawa, Ontario
Aug. 2001
• Winner General Surgery Resident Research Day abstract: Testing the
Efficacy of Specific Anti-a-Gal Antibody Depletion at Prolonging
Survival of an Ex-vivo Porcine Working Heart in Porcine-Human
Apr. 2000
Rizwan A. Manji MD PhD FRCSC MBA
5
Cardiac Xenotransplantation
• Winner Student Research Day (oral presentation), Faculty of
Medicine, University of Alberta
1992
Grants
• Department of Surgery Research Grant ($14997) – The ETHICS
Study – Ensuring patients THrive after prolonged Intensive care
unit stay following Cardiac Surgery – A Pilot Study – Co-
Investigator
• Department of Surgery Research Grant ($8400) – Xenograft Rejection
of Commercially Used Bioprosthetic Heart Valves – Principal
Investigator
• Department of Surgery Research Grant ($14,875) - The Prolonged
Stay Cardiac Surgery ICU Patient: Characterization and Long Term
Outcomes – Principal Investigator
• Anesthesia Oversight Committee Research Awards ($10,000) for
studies in Heparin Induced Thrombocytopenia
Jan 2015 - present
Jan 2015 - present
2013-present
2010
• Manitoba Medical Services Foundation Operating Grant ($35,000) for
work entitled: Stains and Bioprosthetic Heart Valve
Inflammation/Calcification – joint grant with Dr. R. Arora and Dr.
D. Jassal
Dec. 2007
• Alberta Heritage Foundation for Medical Research Fellowship
($30,000/year)
1998-2001
• Edmonton Civic Employees Research Grant ($10,000 per year) – co-
applicant with Dr. A. Koshal
1998-2001
• Medical Research Council Summer Studentship ($5000) 1992
• Alberta Heritage Foundation Summer Studentship ($5000) 1991
Publications
Peer Reviewed Abstracts:
1. Manji RA, Samaha N, Koshal A, Guenther C. Comparison of continuous arterio-venous
hemodialysis with continuous veno-venous hemodiafiltration in the management of acute renal failure
in the cardiovascular surgery intensive care unit. Royal College of Physicians and Surgeons Meeting,
Montreal, Quebec. Sept. 1999.
2. Manji RA, Samaha N, Koshal A, Guenther C. The efficacy of continuous veno-venous
hemodiafiltration in the management of acute renal failure post-cardiopulmonary bypass in the
Rizwan A. Manji MD PhD FRCSC MBA
6
cardiovascular surgery intensive care unit. 4th International Congress on Continuous Renal
Replacement Therapy. San Diego, USA, Mar 1999.
3. Manji RA, Manji JS, Rajotte RV, Afrousian M, Yatscoff R, Koshal A. Specific -gal antibody
removal and human ABO blood group in human-porcine cardiac xenograft survival. Can J Cardiol
2000 Vol 16 Suppl F p.211.
4. Manji R, Manji JS, Koshal A, Afrouzian M, Rajotte RV. Specific -gal removal improves human-
porcine xenograft survival in and ex-vivo porcine working heart model. Clin and Invest Med 2000
Vol 23 (4) p.S6.
5. Manji RA, Manji JS Rajotte RV, Korbutt GS, Afrouzian M, Koshal A. The importance of -gal
antibody removal and human ABO blood group in human-porcine cardiac xenograft survival.
International Society of Cardiothoracic Surgeons – 10th World Congress. Vancouver Canada Aug.
2000.
6. Manji RA, Manji JS, Rajotte RV, Koshal A, Critical factors in survival of a pig-human xenograft. J
Mol Cell Cardiol 2001 Vol 33 (6) p.A7.
7. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Critical factors in survival of pig-human
xenograft. Can J Cardiol 2001 Vol 17 Suppl C p. 243C.
8. Manji RA, Manji JS, Koshal A, Korbutt GS, Rajotte RV. The ideal human ABO blood group and red
blood cells for porcine –to-human cardiac xenotransplantation. Xenotransplantation 2001 Vol 8 Suppl
1 p. 95
9. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Critical factors in survival of a pig-human
xenograft. Clin and Invest Med 2001 Vol 24 (4) p. 223.
10. Manji RA, Manji JS, Koshal A, Korbutt GS, Rajotte RV. The ideal human ABO blood groups for
porcine-human Xenotransplantation. Am J Trans 2001 Vol 1 Suppl 1 p. 457.
11. Manji RA, Manji JS, Koshal A, Korbutt GS, Rajotte RV. Are there ideal blood groups for porcine-
human xenotransplantation? Annual Scientific meeting of Canadian Society of Transplantation, Lake
Louise, Alberta, Mar 2001.
12. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Critical factors in survival of a pig-human
xenograft. 6th World Artificial Organ, Immunology, and Transplantation Society WAITS Ottawa,
Canada. August 2001.
13. Manji JS, Manji RA, Korbutt GS, Rajotte RV, Koshal A. Decreased apoptosis in alpha-gal antibody
depleted human plasma perfused porcine working cardiac xenografts. Can J Cardiol 2002 Vol 18
Suppl 8 p.192B.
14. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Human red blood cells in porcine-human
cardiac xenotransplantation. Can J Cardiol 2002 Vol 18 Suppl B p.209B
15. Manji JS, Manji RA, Korbutt GS, Rajotte RV, Koshal A. Human ABO blood group antibodies and
pig-to-human cardiac xenotransplantation. Can J Cardiol 2002 Vol 18 Suppl B p. 201B.
16. Manji RA, Nijjar N, Woolsey J, Rayner D, Rajotte R, Koshal A, Ross D. Is anti--gal antibody
involved in the failure of glutaraldehyde fixed bioprosthetic heart valves? Can J Cardiol 2004 Vol 20
Suppl D p. 165D
Rizwan A. Manji MD PhD FRCSC MBA
7
17. Manji RA, Nijjar NK, Zhu LF, Rayner DC, Korbutt GS, Churchill TA, Rajotte RV, Koshal A, Ross
DB. Glutaraldehyde-fixed xenograft bioprosthetic heart valve conduits calcify and fail from xenograft
rejection. Can J Cardiol 2005 Vol 21 SupplC p.215C.
18. Manji RA, Zhu LF, Nijjar NK, Rayner DC, Korbutt GS, Churchill TA, Rajotte RV, Koshal A, Ross
DB. Glutaraldehyde-fixed xenograft bioprosthetic heart valve conduits undergo T cell, macrophage
and antibody mediated rejection. Can J Cardiol 2005 Vol 21 Suppl C p.214C.
19. Manji RA, Zhu LF, Nijjar NK, Rayner DC, Rajotte RV, Koshal A, Ross DB. Glutaraldehyde-fixed
heterograft (bioprosthetic) heart valve conduits fail from rejection mediated by T cells, and
macrophages. Exp & Clin Cardiol 2005 Vol 10(1) p. 63.
20. Manji RA, Nijjar N, Zhu LF, Rayner D, Rajotte RV, Koshal A, Ross DB. Glutaraldehyde-fixed
bioprosthetic heart valves fail due to xenograft rejection. 25th annual San Diego Cardiothoracic
Surgery Symposium. San Diego, California. February 2005.
21. Manji RA, Nijjar N, Zhu LF, Rayner D, Rajotte RV, Koshal A, Ross DB. Glutaraldehyde-fixed
bioprosthetic heart valves fail due to xenograft rejection. Annual Meeting of the Society of
Cardiothoracic Surgeons of Great Britain and Ireland. London, United Kingdom. March 2005
22. Manji RA, Nijjar N, Zhu LF, Rayner D, Rajotte RV, Koshal A, Ross DB. Glutaraldehyde-fixed
bioprosthetic heart valves fail due to xenograft rejection. 8th Annual NewEra Cardiac Care:
Innovation & Technology Meeting. Dana Point California. January 2005.
23. Rood PPM, Hara H, Tai H-C, Long C, Ezzelarab M, Lin Y-J, Busch J, Ball S, Ayares D, Wolf R,
Manji R, Bailey L, Cooper DKC. Development of anti-pig (anti-gal and anti-nongal) antibodies in
infant baboons and humans: implications for xenotransplantation. World Transplant Congress, Boston
Massachusetts, July 2006.
24. Kumar K, Durston M, Azordegan N, Bulman C, Moghadasian M, Manji R, Jassal DS, Arora RC.
Natural history of bioprosthetic valve failure. Annual American College of Surgeons Manitoba
Chapter meeting November 2007.
25. Manji RA, Leslie WD, MacWilliam L, Philipp R, Finlayson GS. Are the data any good? Can J
Cardiol 2008 Vol 24 Suppl E P. 258E.
26. Manji RA, Leslie WD, MacWilliam L, Philipp R, Finlayson GS. Does PCI or CABG work long
term? Can J. Cardiol 2008 Vol 24 Suppl E p. 309E.
27. Manji RA, Ross DB, Rajotte RV, Koshal A. Do young patients have antibody-mediated rejection of
bioprosthetic heart valves? Can J Cardiol 2008 Vol 24 Supple E p. 300E.
28. Kumar K, Zarychanski R, Bell D, Zivot J, Lee J Manji R, Menkis AH, Arora RC. The impact of the
Manitoba model of 24 hour in-house intensivists on a dedicated cardiac surgery ICU. Can J Cardiol
2008 Vol 24 Supple E p.113E.
29. Rivet M, Chartrand S, Henry G, Intensive care Cardiac Sciences Nurses, Arora RC, Bell D, Menkis
Ah, Zivot J, Manji RA. Bunk beds in the ICU – Can two cardiac surgery patients occupy one ICU
bed? Can J Cardiol 2008 Vol 24 Suppl E p. 116E.
30. Kumar K, Staniforth C, Durston M, Manji RA, Jassal DS, Arora RC. Can statin therapy alter the
natural history of bioprosthetic valves? Rationale, experimental design, and future implications. 11th
Annual NewEra Cardiac Care Conference. January 2008.
Rizwan A. Manji MD PhD FRCSC MBA
8
31. Manji RA, Ashan MW, CATSS Database Research Group, Kumar A. In septic shock patients with
low cardiac index, initial high or low pulmonary capillary wedge pressure is not useful to determine
ICU outcome. Crit Care Med 2009. Vol 37(12) p. A239.
32. Manji RA, Ashan MW, CATSS Database Group, Kumar A. Patients with septic shock and low
cardiac index have inadequate septic treatment and have worse outcomes. Crit Care Med 2009. Vol
37(12) p. A240.
33. Manji RA, Bell DD, Jacobsohn E, Singal RK, Arora RC, Zivot JB, Menkis AH. Consistent outcomes
despite sicker prolong stay ICU patients – A measure of improved quality of care? Crit Care Med
2009. Vol 37(12) p. A370.
34. Manji RA, Jacobsohn E, Grocott H, Zivot J, Menkis AH. Prolonged in-hospital wait times do not
affect outcomes for urgent coronary artery bypass surgery. American Heart Association, Orlando,
Florida, USA, Nov. 18, 2009. Abstract #4704.
35. Kumar K., Hiebert B, Zarychanski R, Bell DD, Singal RK, Manji RA, Zivot JB, Menkis AH, Arora
RC. Does the use of twenty-four hour, in-house intensivist staffing model in a dedicated cardiac
intensive care unit impact outcomes for prolonged stay (>48 hours) patients? Crit Care Med 2009.
Vol 37(12) p. A311.
36. Kumar K, Zieroth SR, Manji RA, Menkis AH, Freed DH. Influenza A (H1N1) causing biventricular
failure and multi-limb compartment syndrome. Crit Care Med 2009. Vol 37(12) p. A497.
37. Kumar KK, Azordegan N, Durston M, Li Y, Fischer G, Moghadasian M, Manji RA, Freed DH,
Jassal DS, Arora RC. Can statin therapy alter the natural history of bioprosthetic valves? – An in vivo
rodent model pilot study. Can J Cardiol 2009, Vol 25 Suppl B p. 85B.
38. Manji RA, Jacobsohn E, Grocott H, Zivot J, and Menkis AH. Prolonged in-hospital wait times do not
affect outcomes for urgent coronary artery bypass surgery. Can J Cardiol 2009, Vol 25 Suppl B p.
83B.
39. Manji RA, Warrian K, Pascoe E, Lee J, Arora RC, Freed DH, Singal RK, Menkis AH. Over the past
12 years, elderly patients undergoing coronary artery bypass grafting surgery have become sicker
needing more acute care post-op but still have similar mortality rates. Can J Cardiol 2009, Vol 25
Suppl B p.86B.
40. Manji RA, Bell DD, Saw C, Moltzan C, Nickerson P, Menkis AH, Zivot J, Jacobsohn E.
Management suggestions for cardiac surgery patients with a positive heparin induced
thrombocytopenia (HIT) ELISA. Can J Cardiol 2009 Vol 25 Suppl B p.86B.
41. Manji RA, Jacobsohn E, Bell DD, Singal RK, Zivot J, Menkis AH. Delirium and bed management in
the cardiac surgery ICU. Can J Cardiol 2009 Vol 25 Suppl B p.159B.
42. Manji RA, Witt J, Bell DD, Menkis AH, Zivot J, Jacobsohn E. Unfractionated heparin is the least
costly method of routine deep venous thrombosis prophylaxis after cardiac surgery in a model
considering the diagnosis, treatment and management of heparin induced thrombocytopenia. Can J
Cardiol 2009 Vol 25 Suppl B p.159B.
43. Kumar K, Zarychanski R, Bell D, Manji RA, Zivot J, Menkis AH, Arora RC. The impact of 24 hour
in-house intensivist coverage on a dedicated cardiac surgery ICU. Society of Thoracic Surgeons 45th
Annual meeting January 2009.
Rizwan A. Manji MD PhD FRCSC MBA
9
44. Kumar KK, Hiebert B, Zarychanski R, Grocott H, Singal RK, Manji RA, Menkis AH, Arora RC.
Twenty-four hour consultant hybrid ICU: addressing the needs of patients post-cardiac surgery. Can J
Cardiol 2010, Vol 26 Suppl SD Abstract #612
45. Avery LJ, Tam JW, Menkis AH, Shaikh N, Manji RA. What do non-rehab Cardiac Sciences Health
Professionals perceive of and know about cardiac rehab? Journal of Cardiopulmonary
Rehabilitation & Prevention, September/October 2010.
46. Manji RA, Grocott H, Leake J, Khan S, Black K, Manji JS, Menkis A, Strumpher J, Jacobsohn E.
Intermediate term outcomes in ICU patients with seizures following cardiac surgery. Crit Care
Med 2010. Vol 38(12). Abstract 611.
47. Manji RA, Grocott H, Saw C-L, Nickerson, P, Menkis A, Jacobsohn E. What is the usefulness of 4T
Test and Enzyme Linked Immunosorbent Assay in decision making in post cardiac surgical ICU
patients suspected of heparin induced thrombocytopenia? Crit Care Med 2010. Vol 38(12). Abstract
79.
48. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Which cardiac surgery ICU patients with a
positive heparin induced thrombocytopenia ELISA assay are at increased risk for thrombosis?
Canadian Critical Care Forum, November 2010, Toronto, Ontario.
49. Manji RA, Witt J, Menkis AH. A short course of low dose prophylactic steroids is cost-effective in
cardiac surgery ICU patients at medium to high risk for postoperative atrial fibrillation. Canadian
Critical Care Forum, November 2010, Toronto, Ontario.
50. Manji RA, Bell D, Freed DH. Elevated carboxyhemoglobin levels during extra-corporeal membrane
oxygenation for acute lung injury – A case report. Canadian Critical Care Forum, November 2010,
Toronto, Ontario.
51. Manji RA, Grocott HP, Leake JA, Manji JS, Menkis AH, Ariano R, Strumpher J, Jacobsohn E.
Seizures following cardiac surgery: the impact of tranexamic acid and other risk factors. Circulation
Supplement Vol 122 Issue 21 November 23, 2010 – Abstract 18007
52. Manji RA, Grocott HP, Saw C, Nickerson P, Menkis AH, Jacobsohn E. Correlation of the 4T Test,
Enzyme Linked Immunosorbent Assay and the Serotonin Release Assay in post cardiac surgical ICU
patients suspected of heparin induced thrombocytopenia. American Society of Critical Care
Anesthesiologists meeting October 2010, San Diego, California.
53. Manji RA, Grocott HP, Saw C, Nickerson P, Menkis AH, Jacobsohn E. Thrombosis risk in cardiac
surgery ICU patients suspected of having heparin induced thrombocytopenia. American Society of
Critical Care Anesthesiologists meeting October 2010, San Diego, California.
54. Manji RA, Grocott HP, Leake JA, Manji JS, Menkis AH, Jacobsohn E. Risk factors for seizures in
cardiac surgery ICU Patients. American Society of Critical Care Anesthesiologists meeting October
2010, San Diego, California.
55. Manji RA. Ventricular Arrhythmia: Perioperative management. 12th International Congress on
Cardiothoracic and Vascular Anesthesia 2010. Abstract 35. Beijing, China Sept 23, 2010.
56. Manji RA, Bell DD, Loong-Saw C, Nickerson P, Moltzan C, Menkis AH, Jacobsohn E. Treating
cardiac surgery patients for heparin-induced thrombocytopenia based on easily available ELISA
results. Anesthesia and Analgesia 2010. Vol 110 (3) Abstract 71.
Rizwan A. Manji MD PhD FRCSC MBA
10
57. Manji RA, Warkentin TE, Grocott HP, Menkis AH, Jacobsohn E. Pre-operative, intra-operative and
post-operative factors associated with heparin induced thrombocytopenia post cardiac surgery.
Canadian Journal of Cardiology Supplement Vol 27 (5S) September/October 2011 Page S103.
Abstract 111.
58. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Risk factors associated with recurrent seizures
following cardiac surgery. Canadian Journal of Cardiology Supplement Vol 27 (5S)
September/October 2011 Page S195. Abstract 373.
59. Manji RA, Chartrand S, Arora RC, Rivet M, Jacobsohn E, Bell DD, Menkis AH. Which cardiac
surgery patients may be suitable for transfer from ICU the same day as surgery? Canadian Journal of
Cardiology Supplement Vol 27 (5S) September/October 2011 Page S197. Abstract 377.
60. Manji RA, Witt J, Menkis AH. Is it cost-effective to give a short course of low dose prophylactic
steroids to cardiac surgery ICU patients at medium to high risk for postoperative atrial fibrillation.
Canadian Journal of Cardiology Supplement Vol 27 (5S) September/October 2011 Page S288.
Abstract 620.
61. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Recurrent seizures following cardiac surgery - risk
factors and outcomes. Circulation Supplement November 22, 2011, 124 (21):A13710
62. Manji RA, Warkentin TE, Grocott HP, Menkis AH, Jacobsohn E. What is the utility of two different
ELISAs and the 4T's Score in determining the probability of heparin-induced thrombocytopenia
following cardiac surgery? Circulation Supplement November 22, 2011, 124 (21):A13172
63. Villafranca AJ, Arenson B, Grocott H, Manji RA, Jacobsohn E. Is there a difference between cardiac
surgical practice between Canada and the US? Can J Anesth (2012) 59:S123 – Abstract 1343388
64. Manji RA, Arora RC, Bell DD, Menkis AH, Jacobsohn E. Can cardiac surgery patients transfer from
ICU the same day as surgery? Can J Anesth (2012) 59:S108 – Abstract 1341611
65. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Which cardiac surgery ICU patients with a
positive HIT ELISA are at increased risk for thrombosis? Can J Anesth (2012) 59:S113 – Abstract
1341903
66. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Outcomes in ICU patients with seizures post
cardiac surgery. Can J Anesth (2012) 59:S111 – Abstract 1341774
67. Manji RA, Witt J, Jung Y, Northcott R, Jacobsohn E, Menkis AH. Determining the most cost-
effective method to prevent rheumatic heart disease in a developing world country. Accepted for
poster presentation at the American Heart Association Meeting November 4, 2012, Los Angeles,
California, USA
68. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Seizures post cardiac surgery: In-hospital
mortality and intermediate term outcomes. Canadian Journal of Cardiology Supplement Vol 28 (5S)
September/October 2012 Page S362. Abstract 691.
69. Manji RA, Grocott HP, Menkis AH, Jacobsohn E. Aortic surgery patients with a positive HIT
ELISA are at increased risk of thrombosis. Canadian Journal of Cardiology Supplement Vol 28 (5S)
September/October 2012 Page S360. Abstract 687.
70. Manji RA, Witt J, Menkis AH. Is it more cost-effective to use steroids or colchicine in patients at
moderate to high risk for atrial fibrillation to prevent post-cardiac surgery atrial fibrillation? Canadian
Journal of Cardiology Supplement Vol 28 (5S) September/October 2012 Page S384. Abstract 742.
71. Manji RA Witt J, mankis AH. What is the most cost effective method to prevent atrial fibrillation in
patients at medium to high risk for post cardiac surgery atrial fibrillation? Society of Critical Care
Anesthesiologists Annual Meeting, Oct. 2013 San Francisco, California, USA.
Rizwan A. Manji MD PhD FRCSC MBA
11
72. Kumar K, Azordegan N, Durston M, Li Y, Fischer G, Moghadasian M, Manji RA, Freed DH, Jassal
RC, Arora RC. HMG-COA reductase inhibitors do no attenuate the inflammatory response associated
with glutaraldehyde-fixed bioprosthetic heart valve conduits. Can J Cardiol. 2013 Oct; 29(10):S261.
73. Manji RA, Northcott R, Menkis AH. Cardiovascular risk profile in a developing world country –
Rural versus urban differences. Can J Cardiol. 2013 Oct; 29(10):S278.
74. Manji RA, Witt J, Jung Y, Northcott R, Menkis AH. Whit is the most cost-effective method to
prevent rheumatic heart disease in a developing world country? Can J Cardiol. 2013 Oct;
29(10):S324.
75. Manji RA, Northcott R, Menkis AH. Cardiovascular disease risk perception in a developing world
country – based on location of residence and gender. Can J Cardiol. 2013 Oct; 29(10):S324-S325.
76. Nepomuceno R, White CW, Muthiah K, Bueddefield D, Hiebert B, Arora RC, Manji RA, Freed DH,
Moffatt D. Gastrointestinal hemorrhage in adults requiring extracorporeal membrane oxygenation:
Incidence, clinical predictors, and impact on outcomes. Can J Cardiol. 2013; 29(10):S373-S374.
77. Villafranca A, Manji RA, Thomson IA, Arenson B, Lucht J, Jacobsohn E. Differentiation of Heparin
and Non-Heparin Induced Thrombocytopenia Through Early Platelet Measures. Can J Cardiol. 2013;
29(10):S226-S227.
78. Manji RA, Villafrance A, Grocott H, Menkis AH, JacobsohnE. Diagnosing heparin induced
thrombocytopenia post cardiac surgery. American Heart Association Meeting November 2013,
Dallas, Texas USA
79. Manji RA, Menkis AH, Cooper DKC. Xenograft rejection of bioprosthetic heart valves.
Xenotransplantation 2013; 20(5):361
80. Manji RA, Rayner D. Do bioprosthetic heart valves undergo xenograft rejection in patients?
Xenotransplantation 2013; 20(5):373.
81. Manji RA, Rayner D. Anti-alpha-Gal antigen/antibody may not be important in the failure of
bioprosthetic heart valves. Xenotransplantation 2013:20(5):336.
82. Manji RA, Villafranca A, Grocott H, Menkis AH, Jacobsohn E. Testing for Heparin Induced
Thrombocytopenia After Cardiac Surgery. Electronic (moderated) Poster Presentation at Canadian
Anesthesiologist Society Meeting June 13-16, 2014, St. John’s, Newfoundland.
83. Manji RA, Hiebert BM, Arora RC, Moon MC, Freed DH, Menkis AH. Readmission rates and
diagnoses for prolonged intensive care unit stay survivors following cardiac surgery. Can J Cardiol.
2014; 30(10S):S231.
84. Manji RA, Hiebert BM, Arora RC, Moon MC, Freed DH, Menkis AH. Social Assistance
requirements and mental health issues of patients needing prolonged intensive care unit stay
following cardiac surgery. Can J Cardiol. 2014;30(10S):S235.
85. Bednarczyk JM, Ducas RA, White CW, Golian M, Nepomuceno R, Bueddefeld D, Hiebert B, Manji
RA, Singal RK, Hussain F, Freed DH. Extracorporeal membrane oxygenation facilitates survival in
refractory in-hospital cardiac arrest and cardiogenic shock. Can J Cardiol. 2014; 30(10S):S242.
86. Manji RA, Hiebert B, Arora RC, Moon MC, Freed DH, Menkis AH. Characteristics, long-term
survival and predictors of mortality of patients needing prolonged intensive unit care stay post cardiac
surgery. Podium presentation at University of Manitoba Department of Surgery Research Day –
January 19, 2015 – Winnipeg, Manitoba. 87. Manji RA, Hiebert B, Arora RC, Moon MC, Freed DH, Menkis AH. Long Term Survival and
Predictors of Mortality in Patients Needing Prolonged Intensive Unit Care Stay Post Cardiac Surgery.
Podium presentation at the Society of Thoracic Surgery Meeting (Abstract 1542) – San Diego,
California – January 26, 2015.
Rizwan A. Manji MD PhD FRCSC MBA
12
Other Abstracts:
1. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Development of an ex-vivo porcine
working heart model to test various immunoadsorbants for porcine to human xenotransplantation.
General Surgery Resident Research Day, University of Alberta, Edmonton Alberta. Apr 1999.
2. Manji RA, Manji JS, Rajotte RV, Koshal A. Specific -gal antibody removal and human ABO
blood group in human=porcine cardiac xenograft survival. 4th Annual Cardiac Sciences Research
Day, University of Alberta, Edmonton, Alberta, June 2000.
3. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Testing the efficacy of specific anti--gal
antibody depletion at prolonging survival of an ex-vivo porcine working heart in porcine-human
cardiac xenotransplantation. General Surgery Resident Research Day. University of Alberta,
Edmonton, Alberta. Apr. 2000.
4. Manji RA, Manji JS, Rajotte RV, Koshal A. Critical factors in porcine-human Xenotransplantation.
Department of Surgery Resident Research Day, University of Alberta, Edmonton, Alberta, May 2001.
5. Manji RA, Manji JS, Rajotte RV, and Koshal A. Critical factors in survival of a pig-human
xenograft. 5th annual Cardiac Sciences Research Day. University of Alberta, Edmonton, Canada.
June 2001.
6. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Human red blood cells in pig-human
cardiac xenotransplantation. 6th Annual Cardiac Sciences Research Day University of Alberta,
Edmonton, Alberta, Canada. June 2002.
7. Manji JS, Manji RA, Rajotte RV, Korbutt GS, Koshal A. Decreased apoptosis in -gal antibody
depleted human plasma perfused porcine working cardiac xenografts. 6th Annual Cardiac Sciences
Research Day, University of Alberta, Edmonton, Canada. June 2002.
8. Manji JS, Manji RA, Rajotte RV, Korbutt GS, Koshal A. Human ABO blood group antibodies and
pig-to-human cardiac xenotransplantation. 6th Annual Cardiac Sciences Research Day. University of
Alberta, Edmonton, Canada June 2002.
9. Manji RA, Manji JS, Rajotte RV, Korbutt GS, Koshal A. Human red blood cells in porcine-human
cardiac xenotransplantation. Department of Surgery Resident Research Day, University of Alberta,
Edmonton, Canada May 2002.
10. Manji RA, Rayner D, Woolsey J, Nijjar N, Rajotte R, Koshal A, Ross D. Are glutaraldehyde-fixed
bioprosthetic heart valves truly inert? Cardiac Sciences Research Day, Edmonton, Canada June 2004.
11. Manji RA, Nijjar N, Woolsey J, Rayner D, Rajotte R, Koshal A, Ross D. Is anti--gal antibody
involved in the failure of glutaraldehyde fixed bioprosthetic heart valves? Cardiac Sciences Research
Day Edmonton, Alberta June 2004.
12. Kumar K, Durston M, Azordegan N, Bulman C, Moghadasian M, Manji RA, Jassal DS, Arora RC.
Bioprosthetic valve implantation in a rodent model: analysis of the immunological response. Institute
of Cardiac Sciences Research Day, University of Manitoba, Winnipeg, Manitoba. November 2008.
13. Kumar K, Azordegan N, Durston M, Li Y, Fischer G, Moghadasian M, Manji RA, Freed DH, Jassal
DS, Arora RC. Statins compared to steroids on bioprosthetic heart valve inflammation – An In- vivo
Rizwan A. Manji MD PhD FRCSC MBA
13
rodent model study. Institute of Cardiovascular Sciences Research Day, November 2010, Winnipeg,
Manitoba.
Manuscripts and Book Chapters:
1. Bertie JE, Zhang S, and Manji RA, Infrared intensities of liquids X: Accuracy of current methods of
obtaining optical constants from multiple attenuated total reflection measurements using the circle
cell. Applied Spectroscopy 1992; 46:1660.
2. Manji RA and Warnock GL. Left paraduodenal hernia. An unusual case of small bowel obstruction.
Can J Surg 2001; 44(6):455.
3. Manji RA, Manji JS, Koshal A, Korbutt GS, and Rajotte RV. Human ABO blood group is important
in survival and function of porcine working hearts. Am J Trans 2003; 3:286-93.
4. Manji RA, Rajotte RV, Koshal A. human O red blood cells and pig-to-human xenotransplantation.
Xenotransplantation 2004:11:107.
5. Manji RA, Manji JS, Rajotte RV, Koshal A. Xenotransplantation: An Overview. In Pathophysiology
of Cardiovascular Disease. Edited by N.S. Dhalla, H. Rupp, A. Angel and GN Pierce. Kluwer
Academic publishers, Boston 2004:555.
6. Manji JS, Rajotte RV, Koshal A, Manji RA. Increased apoptosis in porcine cardiac xenografts
perfused with human ABO plasma containing the anti-B antibody. Xenotransplantation 2004; 11:378-
9.
7. Manji JS, Rajotte RV, Koshal A, Manji RA, Human anti-A and anti-B antibodies interact with anti-
-gal antibody affecting xenograft survival. Xenotransplantation 2004; 11:376-7.
8. Manji RA Zhu LF, Nijjar NK, Rayner DC, Korbutt GS, Churchill TA. Rajotte RV, Koshal A, Ross
DB. Glutaraldehyde-fixed Bioprosthetic heart valve conduits calcify and fall from xenograft rejection.
Circulation 2006; 114:318-27.
9. Rood PP, Tai H-Chara H, long C, Ezzelarab M, Lin Y-J, van der Windt DJ, Busch J, Ball S, Ayares
D, Ijzermans JNM, Wolf RF, Manji RA, Bailey L, Cooper DKC. Late onset of development of anti-
nongal antibodies in infant humans and baboons: Implications for xenotransplantation in infants.
Transplant International 2007; 20(12):1050.
10. Tam JW, Manji RAS, Shaikh N, Morris A. Diagnostic approach to endocarditis. In Endocarditis:
Diagnosis and Management. Eds.: Chan KL, Embil J, Springe-Verlag, London. 2008; p.63.
11. Schaffer SA, Manji RA, Kirkpatrick I, Fang T, Arora RC, Zieroth S, Jassal DS. Negative pressure
pulmonary edema in the coronary care unit. Can J Cardiol 2008; Sep. 29(9): e58
12. Manji RA, Wood KE, Kumar A. The history and evolution of circulatory shock. Crit Care Clin 2009
Jan. 25(1):1-29, vii.
13. Kumar K, Zarychanski R, Bell DD, Manji RA, Zivot J, Menkis AH, Arora RC. The Impact of 24
hour in-house intensivist coverage on a dedicated cardiac surgery ICU. Annals of Thoracic Surgery
2009 Oct 88 (4): 1153 - 61.
14. Freed D, Henzler D, White C, Fowler R, Zarychanski R, Hutchison JS, Arora R, Manji R, Legare J-
F, Drews T, Veroukis S, Kesselman M, Guerguerian A-M, Kumar A. Extracorporeal lung support for
Rizwan A. Manji MD PhD FRCSC MBA
14
patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in
Canada. Can J Anaesth. 2010 Mar;57(3):240-7.
15. Manji RA, Kumar A. Determining relevant cortisol concentrations in critically ill patients. Critical
Care 2010; 14:113.
16. Paunovic B, Manji RA, Arora R, Strumpher J, Sigal R, Zivot J, Jacobsohn E. Chapter 17: Sepsis and
Vasodilatory Shock in the Cardiac Surgical Patient. In: Sladen RN, ed. Postoperative Cardiac Care.
A Society of Cardiovascular Anesthesiologists Monograph. Baltimore: Lippincott Williams &
Wilkins, 2011:335.
17. Manji RA, Menkis AH, Cooper DK. Cardiac xenotransplantation technology provides materials for
improved bioprosthetic heart valves. J Thorac Cardiovasc Surg 2011 Jul;142(1):238-9.
18. Manji RA, Grocott HP, Leake J, Ariano RE, Manji JS, Menkis AH, Jacobsohn E. Seizures following
cardiac surgery: the impact of tranexamic acid and other risk factors. Canadian Journal of Anesthesia:
Volume 59, Issue 1 (2012), Page 6-13
19. Manji RA, Menkis AH, Ekser B, Cooper DKC. The future of bioprosthetic heart valves. Indian J
Med Res. 2012 Feb; 135(2):150-51
20. Manji RA, Menkis AH, Ekser B, Cooper DKC. Porcine bioprosthetic heart valves: the next
generation. Am Heart J. 2012 Aug; 164(2):177-85.
21. Manji RA, Jacobsohn E, Grocott HP, Menkis AH. Longer in-hospital wait times do not result in
worse outcomes for patients requiring urgent coronary artery bypass graft surgery. Hosp Prac (1995)
2013; 41(3):15-22.
22. Manji RA, Witt J, Tappia PS, Jung Y, Menkis AH, Ramjiawan B. Cost effectiveness analysis of
rheumatic heart disease prevention strategies. Expert Rev. Pharmecoecon Outcomes Res.
2013;13(6):715-24.
23. Manji RA, Menkis AH, Ekser B, Cooper DKC. Bioprosthetic heart valves of the future.
Xenotransplantation 2014; 21(1):1-10.
24. Linkins LA, Warkentin TE, Pai M, Shivakumar S, Manji RA, Wells PS, Crowther MA. Design of
the rivaroxaban for heparin-induced thrombocytopenia study J .Thromb Thrombolysis
2014;38(4):485-92.
25. Manji RA, Cardiac Surgery in the Developing World. Perfusionist 2014; 24(1): p.31
26. Kumar K, Singal R, Manji RA, Zarychanski R, Bell DD, Freed DH, Arora RC; Cardiovascular
Health Research in Manitoba Investigator Group. The benefits of 24/7 in-house intensivist coverage
for the prolonged stay cardiac surgery patient. J Thorac Cardiovasc Surg. 2014 Jul;148(1):290-297.
27. Bednarycyk JM, White CW, Ducas RA, Golian M, Nepomucena R, Hiebert B, Bueddefeld D,
Manji RA, Singal RK, Hussain F, Freed DH. Resuscitative extracorporeal membrane oxygenation
for in hospital cardiac arrest: A Canadian observational experience. Resusciation
2014;85(12):1713-9.
28. Lee W, Hara H, Cooper DK, Manji RA. Expression of NeuGc on pig heart valves.
Xenotransplantation. 2015 Mar 6. doi: 10.1111/xen.12162. [Epub ahead of print]
29. Manji RA, Grocott HP, Manji JS, Menkis AH, Jacobsohn E. Recurrent seizures following cardiac
surgery: risk factors and outcomes in a historical cohort study. Journal of Cardiothoracic and
Vascular Anesthesia (in press - Manuscript Number: YJCAN_3243)
30. Manji RA, Arora RC, Singal RK, Hiebert B, Moon MC, Freed DH, Menkis AH. Long Term
Outcome and Predictors of Non-Institutionalized Survival after Prolonged ICU Stay Post Cardiac
Rizwan A. Manji MD PhD FRCSC MBA
15
Surgery (provisionally accepted for publication in the Annals of Thoracic Surgery pending
revisions– manuscript number ATS/2015/484782).
31. Kumar K, Azordegan N, Durston M, Li Y, Fischer G, Moghadasian M, Manji RA, Freed DH,
Jassal DS, Arora RC. HMG-CoA reductase inhibitors do not attenuate in the inflammatory response
associated with glutaraldehyde fixed bioprosthetic heart valve conduits. (submitted to Circulation)
Invited Presentations
• Xenograft Rejection of Bioprosthetic Heart Valves – Workshop:
Strategies for Overcoming Xenograft Loss – 12th Congress for the
International Xenotransplantation Association – Osaka, Japan
Nov. 13, 2013
• CJOB 680 Radio – World Heart Day – St. Boniface Hospital Global
Heart Initiative
Sept. 29, 2013
• Outcomes of Patients with Prolonged Length of Stay in ICU after
Cardiac Surgery – Combined Cardiac Anesthesia and Cardiac
Surgery Grand Rounds – St. Boniface Hospital – Winnipeg,
Manitoba
Feb. 25, 2015
• Outcomes of Patients with Prolonged Length of Stay in ICU After
Cardiac Surgery – Research in Progress – University of Manitoba
Critical Care Medicine – Winnipeg, Manitoba
Nov. 13, 2014
• Cardiac Surgery in the Developing World – An Update – CSCS
Annual General Meeting at CCS – Vancouver, British Columbia
Oct. 26, 2014
• Cardiac Surgery in the Developing World: Opportunities for the
Cardiac Anesthesiologist – Canadian Anesthesiologist Society
Annual Meeting– St. John’s, Newfoundland
Jun 14, 2014
• Opportunities: Cardiac Surgery in the Developing World – Canadian
Society of Cardiac Surgeons Spring Meeting – Quebec City,
Quebec
Jun 6, 2014
• Colchicine is the Most Cost Effective Method to Prevent Post Cardiac
Surgery Atrial Fibrillation – Critical Care Medicine Research In
Progress Rounds, University of Manitoba, Winnipeg, Manitoba
Dec. 12, 2013
• Opportunities: Cardiac Surgery in the Developing World – Winnipeg
Cardiac Anesthesia, St. Boniface Hospital, Winnipeg, Manitoba
Dec. 3, 2013
• Opportunities: Cardiac Surgery in the Developing World – Canadian
Society of Clinical Perfusion– Montreal, Quebec
Oct 26, 2013
• Opportunities: Cardiac Surgery in the Developing World – Vascular
2013 Conference – Montreal, Quebec
Oct 27, 2013
• Heparin Induced Thrombocytopenia- Critical Care Rounds – Royal
Jubilee Hospital, Victoria, British Columbia
Aug. 30, 2012
Rizwan A. Manji MD PhD FRCSC MBA
16
• Heparin Induced Thrombocytopenia – Cardiology Grand Rounds –
Winnipeg, Manitoba
Jun. 4, 2012
• Seizures Post Cardiac Surgery – Critical Care Medicine Research In
Progress Rounds, University of Manitoba, Winnipeg, Manitoba
Apr. 5, 2012
• Opportunities in the Developing World – Cardiac Sciences Program,
Winnipeg, Manitoba
Mar. 19, 2012
• Heparin Induced Thrombocytopenia – Critical Care Nurses–
University of Manitoba, Winnipeg, Manitoba
Nov. 22, 2011
• Seizures Post Cardiac Surgery – Critical Care Database Meeting –
Winnipeg, Manitoba
Oct. 5, 2011
• Heparin Induced Thrombocytopenia – Department of Anesthesia
Grand Rounds – University of Manitoba, Winnipeg, Manitoba
Sept. 7, 2011
• Heparin Induced Thrombocytopenia – Department of Surgery
Research Rounds– University of Manitoba, Winnipeg, Manitoba
Jan. 14, 2011
• Heparin Induced Thrombocytopenia – Cardiac Surgery Grand
Rounds– University of Manitoba, Winnipeg, Manitoba
Jan. 12, 2011
• Ventricular Arrhythmias: Perioperative Management. 12th
International Congress of Cardiothoracic and Vascular Anesthesia,
Beijing, China
Sept. 23, 2010
• Diabetes: The Basics – Ismaili Muslims Congregation – Winnipeg,
Manitoba
Jun. 3, 2010
• Sharing Best Practices in Cardiac Rehabilitation – “Factors affecting
referrals to cardiac rehabilitation: WRHA Cardiac Sciences Staff
Perceptions”. Canadian Cardiac Rehabilitation Conference,
Edmonton, Alberta
Oct. 25, 2009
• “Heart Valves and Rejection of Bioprosthetic valves” – CJOB Health
Report Broadcast with Stuart Murray, Winnipeg, Manitoba
March 22, 2009
• “Patient Safety and Quality Improvement” – Grand Rounds Critical
Care Medicine, University of Manitoba, Winnipeg, Manitoba
Feb. 18, 2009
• “Patient Safety and Quality Improvement” – Presentation to ICU
Nurses, University of Manitoba, Winnipeg, Manitoba
Feb. 17, 2009
• Cardiovascular Disease – Ismaili Muslims Congregation – Winnipeg,
Manitoba
Feb. 13, 2009
• Cancer Screening - Ismaili Muslims Congregation – Winnipeg,
Manitoba
Jun. 19, 2008
• “Do Bioprosthetic Valves Reject?” – Cardiac Surgery Grand Rounds,
University of Calgary, Calgary, Alberta
March 31, 2006
Rizwan A. Manji MD PhD FRCSC MBA
17
TEACHING
Teaching Experience
• Lecturer – Critical Care Medicine Clinical Assistant Program –
Heparin Induced Thrombocytopenia
Mar 14, 2013
• Lecturer – Critical Care medicine Clinical Assistant program –
Weaning from Mechanical Ventilation and Neuromuscular
Weakness
Mar 14, 2013
• Lecturer – Business Management Issues for ICU - Critical Care
Residents/Fellows, University of Manitoba
October 2011 - present
• Lecturer (with Dr. Julia Witt – Health Economics) - Economic May 2012 - present
• “Databases, Report Cards, Continuous Quality Improvement
Initiatives and Cardiovascular Care in Canada.” 6th Annual
Cardiovascular Trainee Luncheon Co-Chair, Canadian
Cardiovascular Congress, Montreal, Quebec
Oct. 23, 2005
• “Surgical Options for Heart Failure: Expanding Indications for
Cardiac Transplantation and the Future of Xenotransplantation.”
Plenary Session – Postgraduate Day, Canadian Cardiovascular
Congress, Edmonton, Alberta
Oct. 25, 2002
• Open Forum on Xenotransplantation – Expert Panelist for informing
public on the scientific aspects of xenotransplantation
November 3, 2001
• “-gal Antibody Depletion and the Ideal Human Blood Group for
Porcine-Human Cardiac Xenotransplantation.” Alberta Chapter of
the American College of Surgeons, Canmore, Alberta
February 16-19, 2001
• “Porcine-Human Xenotransplantation and Public Health”, Public
Health Sciences Graduate Student Association Public Health Grand
Rounds, University of Alberta, Edmonton, Alberta
Mar. 28, 2001
• “Specific a-Gal Antibody Removal and Human ABO Blood Group in
Human-Porcine Cardiac Xenograft Survival.” Canadian Association
of General Surgeons Resident Research Conference, Parry Sound,
Ontario
June 15-17, 2000
• “Development of and Ex-vivo Porcine Working Heart Model to Test
Various Immunoadsorbants for Porcine to Human
Xenotransplantation, Alberta Research Council, Edmonton, Alberta
Dec. 1999
Rizwan A. Manji MD PhD FRCSC MBA
18
Evaluation of Healthcare Studies – Critical Care Residents/Fellows,
University of Manitoba
• Medical Simulation for Critical Care Residents/ Fellows Nov 2011 – present
• Lecturer – Wean From Ventilation and Neuromuscular Disease in the
ICU – Physician Assistant Lecture Series
Feb 2011 - present
• Lecturer – Heparin Induced Thrombocytopenia – Critical Care
Residents/ Fellows, University of Manitoba
2010 - present
• Lecturer - “Cardiac Surgery for the Medical Student” – Med 3/4
Surgery Students, University of Manitoba
2010 - present
• Lecturer - Abstract Writing– Cardiac Sciences and Critical Care
Residents/Fellows, University of Manitoba
Feb. 2009 - Present
• Lecturer – Patient Safety and Quality Improvement – Cardiac
Sciences and Critical care Residents/Fellows, University of Alberta
Feb. 2009 - Present
• Lecturer and Tutorial Instructor – CV042 “Shock” – Med 1 Students,
University of Manitoba
Oct. 2007 - Present
• Lecturer and Tutorial Instructor – CV042 – “Valvular Heart Disease
Part 2” – Med 1 Students, University of Manitoba
Oct. 2007 - Present
• Tutorial Instructor – Hemodynamics – Med 1 Students, University of
Manitoba
Oct. 2007 - Present
• Lecturer – ICU Nursing Course – “Altered Lab Values” – University
of Manitoba
Oct. 2007 - Present
• Lecturer – ICU Fellows Lecture Series – “Applying Business
Principles to Health Care” – University of Manitoba
Oct. 2007 - Present
• Resident and Medical Student Teaching and Evaluations (ICU
procedures, resuscitation)
July 2005 - Present
• Medical Student Teaching (Surgery Student Interns, Year II Medical
Students) – ward teaching, suture skills, surgery OSCE exams
1996 - 2005
• Advanced Trauma Life Support, Basic Trauma Life Support, and
Advanced Cardiac Life Support Instructor
1998 - 2005
Supervisory Experience
• Summer Student:
o Young Jung – Department of Economics and Pre-med –
CEA for Delirium
Summer 2013
• Summer Students
o Derek Bueddefeld – medical student – Primary supervisor
Summer 2012
Rizwan A. Manji MD PhD FRCSC MBA
19
o Alec Thompson – graduate student – Co-supervisor
o Alex Villafranca – graduate student
o Ben Arenson – summer student
• Summer Students (during my residency)
o Mr. Akil Gulamhusein
o Ms. Nimrit Nijjar
o Ms. Jennifer Woolsey
2001-2004
Administrative/Service
Committees
• Medical Advisory Committee – St. Boniface Hospital, Winnipeg,
Manitoba
2014-present
• The Committee on Management and Governance of Overhead –
University of Manitoba, Winnipeg, Manitoba
2014-present
• ICU Academic Funding Committee – University of Manitoba,
Winnipeg, Manitoba
2014-present
• GFT (geographic full-time) Liason Committee – University of
Manitoba, Winnipeg, Manitoba
2013-present
• Surgery Representative on Canadian Critical Care Society Board of
Directors
2013-present
• Chairman of the Board of Directors – Canadian Humanitarian –
Winnipeg Chapter
Nov 2012-present
• Deep Venous Thrombosis Protocol Policy Committee – Cardiac
Surgery
Jan 2012 - present
• Ventilator Associated Pneumonia Quality Control Committee
Member
Sept 2011 - present
• APPROACH Executive Leader 2010-present
• Member of the Board of Directors of the Canadian Intensive Care
Foundation
Oct. 2009-present
• Treasurer – Canadian Intensive Care Foundation Oct. 2010 - present
• Member of Standards Committee for Cardiac Sciences Program –
Winnipeg Regional Health Authority
May 2009 - Present
• Bleed Audit Committee - Cardiac Surgery 2010 - present
• Residency training Committee – Critical Care Medicine July 2005 - 2007
• Member of Transition Working Group for Trainees for Canadian Mar. 2005 - 2006
Rizwan A. Manji MD PhD FRCSC MBA
20
Cardiovascular Society
• Surgery Resident representative on Surgical Research Committee,
University of Alberta
1999 - 2001
• Medical Student Association’s representative to the General Faculties
Council – University of Alberta
1993 - 1994
Other Administrative/Service
• Examiner for National Assessment Collaboration – Medical Council
of Canada for International Medical Graduates
• Chair Canadian Cardiovascular Congress oral session: Information
Technology in Cardiac Rehabilitation – The Way of the Future
2012 - present
Oct. 2014
• Invited reviewer for “Journal of Medical Economics” Nov. 2014
• Invited reviewer for Donalda Huggins Scholarship Award in
Anesthesia – Dept. of Anesthesia – University of Manitoba,
Winnipeg, Manitoba
2014-present
• Reviewer for journal “Clinical Medicine Insights: Cardiology” June 2014
• Liaison between Canadian Society of Cardiac Surgeons and Cardiac
Centre for Ethiopia for establishment of cardiac surgery program in
Addis Ababa, Ethiopia
2013 - present
• CJOB 680 Radio – World Heart Day – St. Boniface Hospital Global
Heart Initiative
Sept. 29, 2013
• International Medical Graduate OSCE Examiner Sept. 18, 2013 - present
• Invited Reviewer for “Xenotransplantation” Sept. 2013 - present
• Editorial Board of “Journal of Transplantation” Aug 2013 - present
• Invited Reviewer for Journal Biological Medical Research May 2013
• India Canada Culture and Heritage Association Inc. Symposium and
Mentorship Program for Career Development – Medicine as a
Career Choice – Winnipeg, Manitoba
May 4, 2013
• Sanofi BioGENEius Challenge Grade 9-12 Science fair judge - St.
Boniface Research Centre
Mar 21, 2013
• Trip to Ethiopia with Canadian Humanitarian – Echo/Spirometry Feb 2013
• Reviewer for Seizure: European Journal of Epilepsy Jan 2013
• Reviewer for National Research Foundation of South Africa 2012, 2013
• Abstract reviewer for Canadian Cardiovascular Society Annual
Meeting
May 2012-present
Rizwan A. Manji MD PhD FRCSC MBA
21
• Editorial Board – CV Network June 2011- present
• Abstract reviewer for Canadian Cardiovascular Society Annual
Meeting
May 2011
• CIHR High School Student Science Fair Judge – St. Boniface
Research Center
April 2011 and April 2012
• Poster moderator – Society of Critical Care Medicine Annual Meeting January 2011
• External reviewer for Journal – “Circulation” January 2011
• Abstract reviewer – Society of Critical Care Medicine Sept. 2010
• External reviewer “Circulation Surg Suppl” Dec. 2009
• Co-Chair Oral Session – Applied Basic Science II – Canadian
Cardiovascular Congress, Edmonton, Alberta
Oct. 2009
• Grant reviewer for Canadian Critical Care Trials Group/Canadian
Intensive Care Foundation
Oct. 2009-present
• Abstract Reviewer for Canadian Cardiovascular Congress National
Meeting for October 2009
May 2009
• Sponsor for Stuart Clark Entrepreneurial Business Competition –
Asper School of Business – University of Manitoba
April 2008
• Judge at Cardiac Sciences Research Day – University of Manitoba May 2008
• Reviewer for “Journal of American College of Cardiology” Feb. 2008
• Reviewer for “Journal of Cellular and Molecular Medicine” Oct. 2007
• Reviewer for journal “Xenotransplantation” May 2007
• Abstract Reviewer for Canadian Cardiovascular Congress October
2007
May 2007
• Abstract reviewer for Canadian Cardiovascular Congress Oct. 2006 May 2006
• External Reviewer for journal “Circulation” Feb. 2005 - present
• External Reviewer for journal “Nephron” Dec. 2004
• External Reviewer for Candidate for promotion to Research Associate
Professor of Surgery without Tenure, University of Pittsburgh
Sept. 2004
Affiliations/Memberships
• CANCARE October 2014 - present
• Society of Thoracic Surgeons Jan 2011 - Present
• Canadian Critical Care Trials Group Member July 2009 - Present
• Cardiothoracic Surgery Critical Care Association Oct. 2007 - Present
Rizwan A. Manji MD PhD FRCSC MBA
22
• Society of Critical Care Medicine 2005 - Present
• Alpha Omega Alpha Honour Medical Society 1994 – Present
• Canadian Medical Association, Alberta Medical Association 1991 - Present
• Immunology Network Group, University of Alberta 1998 – 2005
• Canadian Association of General Surgeons 1997 - 2001