2009, Volume 10

Eun Seok Gil, Jianshu Li, Huining Xiao, and Tao LuLowe*: Quaternary Ammonium �-Cyclodextrin Nano-particles for Enhancing Doxorubicin Permeabilityacross the In Vitro Blood-Brain Barrier

Page 506. Section 1, Introduction: The Reference 28 in thelast paragraph is deleted.

Page 506. Section 2.2, the synthesis protocol: correct to“Briefly, �-CD (5 mmol, 5.675 g) was dissolved in NaOHaqueous solution (20 mL, 0.9 M) with stirring at 25 °C for 24 h.Choline chloride [2.5 mmol (0.349 g), 10 mmol (1.396 g), 20mmol (2.792 g), or 30 mmol (4.189 g)] was subsequently fedinto the solution and epichlorohydrin [75 mmol (6.939 g)] wasadded at a flow rate of about 0.1 mL ·min-1.” The concentrationof hydrochloride acid solution: correct to 3 M. The denotationfor each QA�CD: correct to “Each QA�CD is denoted as 1-W-N, where W and N denote the feeding molar ratios of epichlo-rohydrin to �-CD and choline chloride to �-CD, respectively.”Reference 28, correct to ref 40.

Page 506. Section 2.3.1, the preparation of QA�CD nano-particle 1-15-2/DOX complexes: correct to “The QA�CDnanoparticle 1-15-2/DOX complexes were prepared by mixingQA�CD 1-15-2 (5 mg ·mL-1, 3.9 mM of �CD unit) and DOX(2.1 mg ·mL-1, 3.9 mM) in D2O at 1:1 molar ratio of DOX to�CD unit, and storing the mixture at 4 °C for overnight.”

Page 514. Section 4, Discussion: The ref 28 in the secondcolumn, last paragraph: correct to ref 40.

BM900279C

10.1021/bm900279cPublished on Web 03/17/2009

Biomacromolecules 2009, 10, 10201020