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Pre Pregnancy Care – A Primary Care Approach - Overview Dr. Sri Wahyu Taher Pakar Perunding Perubatan Keluarga Klinik Kesihatan Simpang Kuala Alor Setar [email protected]

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Page 1: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Pre Pregnancy Care – A Primary Care Approach - Overview

Dr. Sri Wahyu Taher

Pakar Perunding Perubatan Keluarga

Klinik Kesihatan Simpang Kuala

Alor Setar

[email protected]

Page 2: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

FACTS

•4 out of 10 women report that their pregnancies are unplanned

•Perinatal deaths are 50% higher among babies born to adolescent mothers

•Up to 10% of pregnancies among women with untreated gonococcal infections result in perinatal death

Page 3: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

FACTS

• Maternal under nutrition and iron-deficiency anemia account for at least 20% of maternal mortality

• In the absence of interventions, rates of HIV transmission from mother to child are between 15 and 45%

Page 4: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Do we need Pre Pregnancy Care Services in Primary Care Clinics?

• Healthy women getting into pregnancy

• Woman in reproductive age with medical problems conceiving

• Woman with medical risk factors conceiving

• Anticipate a positive outcome with minimal or zero complication

• Comfort / reassurance / confidence

• Plan for future pregnancy

• Comprehensive preparation - BIOPSYCHOSOCIAL

Page 5: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

International Comparisons of

Infant Mortality Rates, 2007 (latest data as of Feb, 2013)

Rank Country Rate

1 Iceland 2.0

2 Sweden 2.5

8 Portugal 3.4

13 Austria 3.7

22 United Kingdom 4.8

24 Canada 5.1

28 United States 6.8

MODs Peristats, 2009

Page 6: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Global Maternal Mortality – 1990, 2005 and 2013

Page 7: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

In 2013, 4.6 million

(74% of all under-five deaths) occurred within the first year of life.

Infant mortality rate total: 13.69 deaths/1,000 live births male: 15.82 deaths/1,000 live births

female: 11.42 deaths/1,000 live births

(2014 estimate - Malaysia)

Infant mortality is closely related to maternal mortality and morbidity

Page 8: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Incidence of Adverse Pregnancy Outcomes,

most recent years

Spontaneous Abortion 20% (estimated average)

Infant Mortality 6.6/1000 live births (2008)

Fetal Mortality 6.2/1000 live births plus fetal

deaths (2005)

Major Birth Defects 3.3% (2002)

Low Birth Weight 8.1% (2010)

Preterm Delivery 12.0% (2010)

Complications of Pregnancy 30.7% (CDC data, 2002)

Unintended Pregnancies 49% (2006)

Unintended Births 31% (2006)

Page 9: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy
Page 10: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

So why is Pre Pregnancy Care Important?

Page 11: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

NHMS 2015

Page 12: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

11.6

15.2

17.5

7.0 7.2

8.3

4.5

8.0

9.2

4.2 4.9 4.7

0.0

2.0

4.0

6.0

8.0

10.0

12.0

14.0

16.0

18.0

20.0

NHMS III (2006) NHMS 2011 NHMS 2015

Pre

vale

nce

(%

)

Prevalence of Diabetes, ≥18 years (2006, 2011, 2015)

Total diabetes Known Undiagnosed IFG

Page 13: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Prevalence of Diabetes, ≥ 30 Years, NHMS (1996, 2006, 2011 and 2015)

8.3

14.9

20.8

22.5

6.5

9.5

10.7 10.6

1.8

5.4

10.1

11.9

0.0

5.0

10.0

15.0

20.0

25.0

NHMS 1996 NHMS 2006 NHMS 2011 NHMS 2015

Total Known Undiagnosed

Pre

vale

nce

(%

)

Page 14: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

0.0 0.7

1.4

3.4 3.4

6.9

10.5

14.8

20.6

26.5

24.4

27.9

24.4

5.5 5.2

7.4 7.2

9.5 11.0 11.5

12.2 12.4 11.8

13.6

11.2 12.6

5.5 5.9

8.9

10.6

12.9

17.6

22.0

27.0

32.9

38.3 38.0 39.1

37.0

3.6 3.6 3.9 3.9 4.6

6.0 5.8 5.8 5.9 5.5 4.8 5.4 6.0

0.0

5.0

10.0

15.0

20.0

25.0

30.0

35.0

40.0

45.0

Pre

vale

nce

(%

)

Prevalence of Diabetes, ≥18 years, by age groups (2015)

Known Undiagnosed Total diabetes IFG

Page 15: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Prevalence of Diabetes, ≥18 years, by Ethnicity (2015)

14.6

9.0 9.8

5.2

12.0

7.7 7.7

3.8

22.1

16.0

11.9

7.7

10.7

6.8 8.1

3.1

7.4

2.5

8.6

4.3

0.0

5.0

10.0

15.0

20.0

25.0

Total Diabetes Known Diabetes Undiagnosed DM IFG

Malay Chinese Indian Other Bumiputras Other

%

Page 16: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

19.8

25.4

18.5

16.7

19.3

14.8

18.1 19.4

20.6

15.5

18.6

14.2 14.8

17.4

19.2

0.0

5.0

10.0

15.0

20.0

25.0

30.0

Pre

vale

nce

(%

)

Prevalence of Diabetes, ≥18 years, by States (2006, 2011 & 2015)

NHMS III (2006) NHMS 2011 NHMS 2015

Page 17: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Intendedness of conception

Interpregnancy interval

Maternal age

Exposure ART/ovulation stimulation

Spontaneous abortion

Abnormal placentation

Chronic disease control

Congenital anomalies

Timing of entry into prenatal care

Important Examples of Determinants Poor Maternal & Perinatal Outcome

Page 18: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy
Page 19: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

In obstetrics,

many of our

outcomes or their

determinants are

present before we

ever meet our

patients

Page 20: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

The preconception movement is based on the

realization that:

Prenatal care starts too late to prevent

many of these poor pregnancy outcomes

Women who have higher levels of health

before pregnancy have healthier

reproductive outcomes

Page 21: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Evidence for PPC relevance

Page 22: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Evidence for its relevance

• PPC was a/w improved glycaemic control in early pregnancy and significant reductions in adverse pregnancy outcome (malformation, stillbirth and neonatal death) and very prematurity (Temple et al; Diabetes Care Vol 29, 2006)

• Preconception health status plays a fundamental role in determining risk for adverse pregnancy-related outcomes - WHO

Page 23: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Evidence for its relevance

•High HbA1c and T2DM independently is associated with serious adverse fetal outcome (Clausen et al;Diabetes Care, 2005)

•Pregnancy outcome in T2DM are better in c/w T1DM mothers when given equal pre pregnancy care intensified medical treatment (Hillman & Herranz; Diabetes Care vol 29, Nov 2006)

Page 24: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Statistics – How did we do past few years?

Page 25: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

0

5

10

15

20

25

0.0

10.0

20.0

30.0

40.0

50.0

60.0

70.0

2012 2013 2014 2015 2016 2017

No. of Death 14 8 18 23 15 15

MMR Kedah 39.3 22.3 50.2 64.8 40.8 40.8

Mat

ern

al d

eath

/10

0 0

00

LB

Source of data: MMR (Kedah) from HIMS reten

Nu

mb

er o

f d

eath

Data merujuk kepada semua jenis kematian (all pregnancy related death)

MATERNAL MORTALITY RATIO KEDAH 2012 – 2017

Page 26: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

26.7%

46.6%

26.7%

13.4%

46.6%

40.0%

0 2 4 6 8 10 12 14 16

2016

2017

2016 2017

Direct 4 7

Indirect 4 2

Fortuituos 7 6

TOTAL 15 15

KLASIFIKASI KEMATIAN IBU NEGERI KEDAH 2016 - 2017

Page 27: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

53.30%

53.30%

46.70%

46.70%

0% 20% 40% 60% 80% 100%

2016

2017

Preventable Non Preventable

PREVENTABLE / NON PREVENTABLE BY CAUSES OF DEATH 2016 - 2017

PREVENTABILITY

PPH

PULMONAR

Y

EMBOLISM

AMNIOTIC

FLUID

EMBOLI HDP Medical Other

‘16 ‘’17 ‘16 ‘’17 ‘16 ‘17 ‘16 ‘17 ‘16 ‘17 ‘16 ‘17

Yes 1 4 0 1 0 0 0 0 4 2 3 0

No 0 - 1 1 1 1 0 0 1 4 3 2

Total 1 4 2 2 1 1 0 0 5 6 6 2

Page 28: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

BILANGAN KEMATIAN IBU MENGIKUT DAERAH TAHUN 2015 – 2017 NEGERI KEDAH

DAERAH ESTIMATED LIVE BIRTH

NO. OF MATERNAL DEATHS (RATES PER 100 000 LB)

BALING 2885

BANDAR BHARU 803

KOTA SETAR 7084

KUALA MUDA 7887

KUBANG PASU 4269

KULIM 4853

LANGKAWI 1886

PADANG TERAP 1441

PENDANG 2229

SIK 1432

YAN 1186

NEGERI KEDAH 36784

2015 2016 2017

1 (34.6) 2 (69.3) 2 (69.3)

1 (12.4) 0 0

4 (56.4) 2 (28.2) 0

7 (88.7) 2 (25.3) 6 (76.1)

2 (46.8) 1 (23.4) 0

3 (61.8) 4 (82.4) 4 (82.4)

2 (10.6) 1 (53.0) 2 (10.6)

0 1 (69.4) 1 (69.4)

0 0 0

1 (69.8) 1 (69.8) 0

2 (16.8) 1 (84.3) 0

23 (62.5) 15 (40.7) 15 (40.7)

Page 29: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

TAHUN JUMLAH WANITA DI SARING

JUMLAH RISIKO KESIHATAN

DIKESAN

PERATUS RISIKO KESIHATAN DIKESAN DALAM KALANGAN WANITA DISARING

2011 19349 7890 39.2

2012 25 544 8153 31.9

2013 29135 8507 29.2

2014 34925 8764 25.1

2015 39537 9193 23.3

2016 38245 11084 29.0

2017 35043 11960 34.1

PERKHIDMATAN PPC DI KLINIK KESIHATAN 2011 – 2017

Page 30: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

PPC MENGIKUT ENTRY POINT DI KLINIK KESIHATAN 2017 NEGERI KEDAH

BALINGBANDA

RBHARU

KOTASETAR

KUALAMUDA

KUBANG PASU

KULIMLANGKA

WI

PADANG

TERAP

PENDANG

SIK YAN

KD 186 178 123 232 0 775 112 157 35 18 111

KEMKESIHATAN

0 4 0 0 0 0 0 0 0 0 16

UPL 171 131 1240 1020 474 1037 247 71 256 271 142

MCH 194 132 1219 467 610 528 521 252 382 232 416

35.2% 29.7%

47.2%

27.2%

56.3%

22.6%

59.2% 52.5% 56.8%

44.5%

60.7%

31%

29.4%

48%

59.3%

43.7%

44.3%

28.1%

14.8%

38% 52% 20.7%

0

0.9%

0

0

0

0

0

0

0 0

2.3% 33.8% 40%

4.8% 13.5%

0

33.1%

12.7%

32.7%

5.2% 3.5%

16.3

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

PER

ATU

S

Axis Title

JUMLAH 551 445 2582 1719 1084 2340 880 480 673 521 685

* Fokus utama PPC di UPL : Kuala Muda, Sik, Kota Setar (Shift from MCH ke UPL entry point)

Page 31: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

HPT DM AnemiaBad

Obs HxThyrotoxicosis

HeartDis

Epilepsy

CTD Mental Asthma RV+ve STI Obesiti Others

2015 23.2 23.5 2.6 5.5 1.5 1.3 0.3 0.01 0.1 1.3 0.1 0.1 1 3.9

2016 24.6 30.3 2.1 18 1.4 0.9 10.3 0.1 0.3 4.7 0.1 0.03 3.5 13.7

2017 18.5 26 1.8 18.8 1.3 0.8 0.3 0.01 0.3 4.6 0.1 0.1 13.4 14

0

5

10

15

20

25

30

35

PER

ATU

S PPC BERDASARKAN FAKTOR RISIKO 2015 – 2017 NEGERI KEDAH

Peningkatan risiko kesihatan obesiti

Page 32: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy
Page 33: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

ISU KEMATIAN IBU PERKARA ISU

Direct cause

Kematian yang boleh dicegah disebabkan oleh PPH (3) dan HDP (2) disebabkan oleh: -Lewat mengenalpasti dan merawat PPH - Kelemahan pengendalian Placenta Praevia Major di swasta - kelemahan monitoring pre eclampsia - kelemahan pengendalian hypertensive crisis di swasta

Indirect cause -Ibu hamil dengan penyakit kronik tidak mendapat kaunseling secukupnya (PPC) tentang risiko kehamilan semasa merancang untuk hamil - Gagal kenalpasti keterukan penyakit dan tidak merujuk kes

Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua peringkat jagaan

Page 34: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Absolute Contraindication for Pregnancy (to be follow up/register at PPC)

High grade Pulmonary Hypertension of Any Origin (≥50% of systemic pressure)

Eisenmenger Syndrome

Severe Heart Failure (NYHA class III/IV)

Severe Left Heart Obstruction (Aortic Stenosis with average pressure gradient >50 mmHg, High grade Aortic isthmus stenosis –recurrent)

Severe Mitral Stenosis (Average pressure gradient > 10 mmHg, valve aperture area < 1cm2)

Marfan Syndrome with ectasia of the aorta ascendens(≥ 45mm)

Cyanotic Heart Disease (especiallywith oxigen saturation < 80%)

Page 35: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

What did we do?

Page 36: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Health

Maintenance

Post

Reproductive

Years

Pre-pregnancy

Planning Pregnancy Postpartum

Newborn (a new life)

The Women’s Health Continuum

A set of intervention that aim to identify and modify biomedical, behavioural, and social risks to a woman’s health or pregnancy outcome through prevention and management, emphasizing those factors that must be acted on before conception or early in pregnancy to have maximal impact (CDC,2006)

Definition-PRE PREGNANCY CARE (PPC)

Page 37: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Process of care PPC in Health Clinics and Hospitals

Health Clinics Klinik Bandar Hospital

MCH: Family Planning Child Health services Postnatal services Women’s health

OPD: NCD Wellness services Premarital screening Thalasemia screening Adolescent services MMT/NSEP

OPD: NCD Wellness services Premarital screening Thalasemia screening Adolescent services MMT/NSEP

Specialist clinics: MOPD SOPD O&G Orthopaedic Cardiology Nephrology

Women in reproductive age of 15-55 years Women in reproductive age of 15-

55 years

Risk Factor?

Absent Present

History taking by screening format Physical Examination Laboratory investigation

Refer MO/FMS

*Referral

Follow up

Pre-pregnancy care (integrated) Counseling

Health education Family Planning Preparation for next pregnancy

PPC in O& G Hospital

History taking by screening format Physical examination Laboratory investigation

Follow up

Page 38: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy
Page 39: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Pre Pregnancy Care / Pre Conception Care

• To be made available to all women

• Not only to women who wishes to conceive

• But all woman in reproductive age who has the potential to conceive

• With or without partner

• Gives an opportunity for health screening and care

• Primary interventions

Page 40: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Examples of Primary Prevention Opportunities: Congenital Anomalies

The Opportunity: The Potential Benefit:

Prevention of neural tube defects

50-70% can be prevented if a woman

has adequate levels of folic acid

during earliest weeks of

organogenesis—before she receives

her prenatal vitamins

Birth Defects related to poor glycemic

control of mother (including sacral

agenesis, cardiac defects and neural

tube defects)

Can be reduced from ~10% to 2-3%

through glycemic control of the

woman before organogenesis

Page 41: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Examples of Primary Prevention Opportunities: Congenital Anomalies

The Opportunity: The Potential Benefit:

Minimize a prospective

mother’s contact with

teratogenic exposures such

as prescribed medications,

environmental exposures and

alcohol

Teratogenic substances

interfere with normal organ

development primarily during

the period of organogenesis

Page 42: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

PPC in Kedah

• We started to do the ground work in 2010

• Guideline and general flow process 2011

• Implementation one KK one district – middle of 2011

• Implementation of all KKs – 2012

• Implementation in hospital 2013 – there was a glitch – no budget for family planning, so a bit delayed

• 2014 – PPC at hospital

• Implementation and collaboration between KK and hospital strengthened – middle of 2014

• 2015 – KK started to receive budget for Implanon NXT

• 2016 – auditing at KK

• 2016 onwards plan of action and further strengthening of the program

Page 43: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

What did we offer?

Primary Prevention Opportunities

Page 44: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

PPC in Kedah – Primary Care a Broader Perspective

• Target – women in reproductive age – 16 to 50 of age

• Screening for potential medical condition

• Intervention to the high risk group

• Intervention for the pre diabetes / obese

• Optimization for their medical conditions

• Stress management

• Family Planning

• Vaccination

• Psychosocial support

Page 45: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Who are in the PPC team?

All Levels of Health Care Providers

(Multidisciplinary Team Based Approach)

Page 46: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

Team Members

• Doctors / FMSes

• Paramedics

• Nurse Educator

• Dietician / Nutritionist

• Physical Therapist / Physiotherapist

• Occupational Therapists

• Pharmacist

• Psychologist / counselor

• O & G specialists / medical and other specialties (referral point)

Page 47: Pre Pregnancy Care A Primary Care Approach - Overvie Pregnancy Care.pdf · Pakar Perunding Perubatan Keluarga ... Fortuitous -Kegagalan mengesan/diagnosa penyakit pada semua ... Pre-pregnancy

• Established Diabetes Mellitus / Newly Diagnosed Diabetes Mellitus in pregnancy / GDM – IGT – Diet Control / Positive OGTT 6 weeks post partum

• In reproductive age (16 – 50)

• Men / husband / partner

• Any woman with medical conditions / risk factor

• Refer individually / together with partner

Who to refer to PPC

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•Hospital with specialist

•Hospital without specialist

•Health Clinics (OPD/MCH) •GP clinics

•Private Medical Centers

•RSAT •LPPKN

Who can refer

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Primary Care Perspectives

• FMS to lead the team • Integration of all discipline for one aim • Intervention programs • Can be conducted at OPD / Family Health Unit / NCD

unit • Continuity of care cycle between antenatal and PPC

Services • Multiple point of entries (child health / maternal /

BSSK / OPD / Chronic Disease Care unit / Saringan Pra Perkahwinan etc)

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PPC – at tertiary / secondary level

• Receive referral cases at various point of entry

• Co-ordination and joint care with other disciplines

• Handles difficult cases that need sub specialized counseling eg. Genetic counseling etc.

• Referral back to primary care

• Able to focus on complicated cases

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Flow Chart PPC in Kota Setar

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Components of Pre Pregnancy Care

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Components of Pre Pregnancy Care

• Risk assessment (screening)

• Health promotion (primary prevention example vaccine)

• Interventions for identified risks (intervention of medical / psychological / social risk factors)

• Optimization & intensification of various medical conditions

• Family Planning (integration with Wellness Clinic)

• Implementation and monitoring

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Pre Pregnancy Care Risk Assessment (1)

• Reproductive life plan

• Reproductive history

• Medical and surgical history

• Medication use

• Infections and immunizations

• Genetic screening and family history

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Pre Pregnancy Care Risk Assessment (2)

• Nutritional assessment

• Smoking & Substance abuse

• Toxins and teratogenic agents

• Psychosocial concerns

• Physical exam

• Laboratory testing

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Pre Pregnancy Care Health promotion

• Family Planning

• Healthy weight and nutrition

• Healthy behaviors

• Stress resilience

• Healthy environments

• Inter-conception care

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Pre Pregnancy Care - Interventions for Identified Risks & Medical Conditions

• Folic acid supplementation

• Rubella testing, vac. If necessary

• Control of pre-gestational DM

• Management of hypothyroidism, HPT etc

• Avoidance of teratogenic agents like accutane, coumadin, some anticonvulsants, alcohol, tobacco

• NCD intervention program

• Optimization & Intensification

• Referral if necessary

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Pre Pregnancy Care - Implementation

• PPC should not occur only in selected in primary care clinics

• It should be implemented in all primary care clinics & hospitals

• Private and government (including collaboration) • Should be for all women in reproductive age –

opportunistic modality • Every women must have a reproductive life plan • Men should be involved • If planning for a conception – PPC should be regular • PPC should be promoted in the community –

awareness drive / campaign etc

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Family Planning

• WHO Medical Eligibility Criteria

• Patient friendly

• Acceptable to patient and husband

• Availability

• Refer to O & G clinic for further assistance

• Refer to health clinics if patient can’t afford from private

• Promote universally

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Male Role in Preparing for Pregnancy

Male planning to become father should:

Review family medical & genetic hx

Practice STD risk-reduction behaviors.

Avoid tobacco, alcohol, illicit/street drugs,

chemical exposure.

Assess financial status.

Be supportive of partner.

Play active role in pre-pregnancy planning.

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PPC Check List

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Flow Chart Defaulter Tracing

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On going process of strengthening PPC

(audits, improvement and plan of action)

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Defaulter Tracing Team

• Done in OPD / multidisciplinary referral system within KK

• FMS leader

• 2 MOs in charge / PJ / JK / JM / PPP (kanan)

• Documentation – clear & legible & complete

• Registration

• Defaulter tracing – every 2 weeks (JM) > trace card > matron audit > trace patient

• Audits – MO or FMS

• Charting and updating registration – JM / SN

• BSSK issues

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Weakness points

• Missed registration

• Defaulter tracing poor

• Poor charting

• Clinical audit – MO does not fulfil component of PPC, commonly on FP, supplementation, other disease screening example anemia

• Patients were not treated to target

• No definitive counseling example – ‘not to conceive until HbA1C < 6.5%’

• Type of family planning

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PPC Clinical Audit Component

• Optimization of existing Medical Illness • Screening for other medical condition (NCD, STIs) • Managing patient using team based multidisciplinary

approach (Physio, OT, PSP, Dietician, Pharmacist, Hospital Referral)

• Supplementation (example iron, folic acid) • Social (smoking, substance abuse) • Vaccination • Genetic counseling / referral • Mental health screening • Family Planning • Management of other medical conditions example

obesity, dyslipidaemia

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Remedial Measures

• Activity of PPC team in line with pelan tindakan kesihatan keluarga negeri 2016 / 2017 / 2018

• Every team member has specified duty / responsibility • Example – JM – Defaulter tracing, registration, card tracing • JK – screening, registration, charting, basic counseling • FMS / PJ / MOs – audit, monitoring, meetings, planning,

strategizing • CMEs, FAQ confrontation to staffs, drills, case scenarios • Regular audits • Implementation of FDC • Meetings on pencapaian /audit every 3 months (now every 4 months)

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Benefits of Pre Pregnancy Care

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Giving Protection

Examples of giving protection: • Folic acid supplementation to protect against neural tube defects and

other congenital anomalies

• Examples of immunizations against infectious diseases that can impact pregnancy outcomes:

• Rubella

• Varicella

• Hepatitis B

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Preconception Interventions: Give protection

•Folic Acid Supplements: Reduce the occurrence of neural tube defects by two thirds

•Rubella Sero-negativity: Rubella immunization provides protective sero-positivity and prevents the occurrence of congenital rubella syndrome

•HIV/AIDS: timely antiretroviral treatment can be administered, pregnancies can be better planned

•Hepatitis B: Vaccination is recommended for men and women who are at risk for acquiring hepatitis B virus (HBV) infection.

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Managing Conditions

Examples of conditions known to be detrimental to reproductive outcomes if in poor control before conception:

•Diabetes

•Maternal PKU

•Obesity

•Hypothyroidism

•Sexually transmitted infections

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Preconception Interventions: Manage conditions

•Diabetes: 3-fold increase in birth defects among infants of women with type

1 and type 2 diabetes, without management

•Hypothyroidism: Dosage of Levothyroxine should be adjusted in early

pregnancy to maintain levels needed for neurological development

•Maternal PKU: Low phenylalanine diet before conception and

throughout pregnancy prevents mental retardation in infants born to mothers

with PKU

•Obesity: Associated adverse outcomes include neural tube defects, preterm

birth, c-section, hypertensive and thromboembolic disease.

•STDs: have been strongly associated with ectopic pregnancy, infertility, and

chronic pelvic pain.

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Avoiding Exposures

Examples of exposures known to be teratogenic or otherwise harmful in early pregnancy:

• Medications: • Many antiseizure medications

• Oral anticoagulants

• Accutane

• Others

• Alcohol

• Tobacco

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SUBSTANCE USE

Impact of alcohol use on women’s health:

• Risk for motor vehicle and other accidents

• Risk for unintended pregnancy

• Risk for addiction

• Risk for nutritional depletions and inadequacies

Impact of alcohol use on reproductive outcomes:

• Delayed fertility

• Increased SABs

• Fetal alcohol spectrum disorders (full fetal alcohol syndrome can only occur with fetal exposure between days 17-56 of gestation)

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SUBSTANCE USE

Impact of tobacco use on women’s health:

• Implicated in most of the leading causes of death for women:

• Heart disease (#1 cause of death)

• Stroke (#2)

• Lung cancer (#3)

• Lung disease (#4)

Impact of tobacco use on reproductive outcomes:

• Leading preventable cause of infant mortality and morbidity

• Preventable cause of low birth weight and prematurity

• Associated with placental abnormalities including placenta previa and placenta abruptio

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Controllable Risk Factors: Drug, Alcohol, Tobacco Use

Alcohol:. Avoid all alcohol during time attempting conception/pregnancy.

No known safe level during pregnancy. Associated with malformation, slow fetal growth, fetal death, low birth-weight, CNS abnormalities, neurologicaldefects, spontaneous abortion, abruption.

Tobacco: Associated with spontaneous abortion, ectopic pregnancy; low birth-weight, infant mortality. Can potentially decrease fertility. Vasoconstriction restricts blood flow to fetus & reduces % of oxygen & nutrients carried by blood.

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Illicit or Street Drugs: May be associated with severe medical & developmental problems in newborns.

1. Marijuana, most common - tend to have babies earlier & may be smaller than term babies.

2. Cocaine: associated with miscarriage, abruption, low birth-weight, premature birth, brain damage.

3. Heroin - IV drug users - evaluate for AIDS & Hep B. In HIV + women, studies show treatment with AZT reduces transmission to baby from ~ 25% to 8%.

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NUTRITIONAL STATUS: Obesity

Impact of obesity on women’s health:

• Diabetes

• Hypertension

• Cardiovascular disease

• Disabilities

Impact of maternal obesity on reproductive outcomes:

• Glucose intolerance of pregnancy

• Pregnancy induced hypertension

• Thrombophlebitis

• Infertility

• Neural tube defects

• Prematurity

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NUTRITIONAL STATUS: Underweight

Impact of being underweight on women’s health:

Risk of osteoporosis in later life

Fragile health status

Impact of low pregravid weight on reproductive outcomes:

Infertility

Low birth weight

Prematurity

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Supplementation

• Supplementation – (only 15.2% women in Malaysia have adequate folate from dietary intake that have adequate protections against NTD at birth) – obese women need a higher level of folate intake (0.6 mg daily)

• Folate – at least 3 months prior to pregnancy

• Calcium supplement?

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Evidence-based interventions: Selected examples

• Screening for anemia • Taking a thorough family history • Family planning • Genetic counselling • Carrier screening and testing • Appropriate treatment • Providing community-based education • Community-wide or national screening

among populations at high risk • Population-wide screening

Genetic conditions

Areas addressed by the

preconception care package

Evidence-based interventions

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Evidence-based interventions: Selected examples

• Keeping girls in school • Influencing cultural norms that support early marriage and

coerced sex • Creating visible, high-level support for pregnancy prevention

programmes • Educating girls and boys about sexuality, reproductive health

and contraceptive use • Building community support for preventing early pregnancy

and for contraceptive provision to adolescents • Enabling adolescents to obtain contraceptive services • Empowering girls to resist coerced sex • Engaging men and boys to critically assess norms and practices

regarding gender-based violence and coerced sex • Educating women and couples about the dangers to the baby

and mother of short birth intervals • Providing contraceptives

Too-early, unwanted and rapid successive pregnancy

Areas addressed by the preconception care package

Evidence-based interventions

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Stress Management Techniques

Relaxation & deep breathing. Planning

pregnancy can be stressful.

Stress reduction enhances chances of

conception.

Excessive stress can lead to premature birth & low

birth weight. Sleep 8-10 hr.with frequent rest periods a

day.

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Conclusion

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For Every Woman of Childbearing Potential, Every Time She is Seen

• Identify modifiable and non modifiable risk factors for poor health and poor pregnancy outcomes before conception

•Provide timely counseling about risks and strategies to reduce the potential impact of the risks

•Provide risk reduction strategies consistent with best practices.

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“Every Woman, Every Time” is Opportunistic Care

• Takes advantage of all health care encounters to stress prevention opportunities throughout the lifespan

• Recognizes that in almost all cases preconception wellness results in good health for women, irrespective of pregnancy intentions

• Addresses conception and contraception choices at every encounter

• Involves all medical specialties—not only those directly involved in reproductive health

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