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Chapter 12
*Lecture Outline
*.
2
12.1: Introduction
• General senses
• Receptors that are widely distributed throughout the body
• Skin, various organs and joints
• Special senses
• Specialized receptors confined to structures in the head
• Eyes, ears, nose and mouth
3
12.2: Receptors, Sensation,
and Perception
• Sensory receptors
• Specialized cells or multicellular structures that collect
information from the environment
• Stimulate neurons to send impulses along sensory
(afferent) fibers to the brain
• Sensation
• A feeling that occurs when brain becomes aware of
sensory impulse
• Perception
• A person’s view of the stimulus; the way the brain
interprets the information
4
Pathways From Sensation to Perception
(Example of an Apple)
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TABLE 12.1 | Information Flow from the Environment Through the Nervous System
Sensory receptors Olfactory receptor
cells
Taste bud receptor cells Rods and cones in retina Hair cells in cochlea
Impulse in sensory fibers Olfactory nerve fibers Sensory fibers in various cranial nerves Optic nerve fibers Auditory nerve fibers
Midbrain and cerebral cortex Midbrain and cerebral cortex
Sensation (new experience,
recalled memory)
A sweet taste A small, round, red object
Information Flow Smell Taste Sight Hearing
Impulse reaches CNS Cerebral cortex Cerebral cortex
A crunching sound
Perception The smell of an apple The taste of an apple The sight of an apple The sound of biting into an apple
A pleasant smell
5
Receptor Types
• Chemoreceptors
• Respond to changes in chemical concentrations
• Pain receptors (nociceptors)
• Respond to chemicals released during tissue damage
• Thermoreceptors
• Respond to changes in temperature
• Mechanoreceptors
• Respond to mechanical forces (touch, stretch, pressure)
• Photoreceptors
• Respond to light
6
Sensory Impulses
• Stimulation of receptor causes local change in its receptor potential
• A graded electrical current is generated that reflects intensity of
stimulation
• If receptor is part of a neuron, the membrane potential may generate
an action potential
• If receptor is not part of a neuron, the receptor potential must be
transferred to a neuron to trigger an action potential
• Peripheral nerves transmit impulses to CNS where they are analyzed
and interpreted in the brain
7
Sensations and Perception
• Projection
• Process in which the brain projects the sensation back to
the apparent source
• It allows a person to pinpoint the region of stimulation
8
Sensory Adaptation
• Ability to ignore unimportant stimuli
• Involves a decreased response to a particular stimulus
from the receptors (peripheral adaptation) or along the
CNS pathways leading to the cerebral cortex (central
adaptation)
• Sensory impulses become less frequent and may cease
• Stronger stimulus is required to trigger impulses
9
12.3: General Senses
• Senses associated with skin, muscles, joints and viscera
• Three (3) groups: • Exteroceptive senses (exteroceptors)
• Senses associated with body surface such as touch,
pressure, temperature, and pain
• Visceroceptive senses (interoceptors)
• Senses associated with changes in the viscera such as
blood pressure stretching blood vessels and ingestion of a
meal
• Proprioceptive senses
• Senses associated with changes in muscles and tendons
such as at joints
10
Touch and Pressure Senses
Free nerve endings
• Common in epithelial
tissues
• Simplest receptors
• Sense itching
Tactile (Meissners) corpuscles
• Abundant in hairless portions of
skin and lips
• Detect fine touch and texture
Lamellated (Pacinian) corpuscles
• Common in deeper subcutaneous
tissues, tendons and ligaments
• Detect heavy pressure and vibrations
11
Touch and Pressure Receptors
Epidermis
Dermis
(a)
(b)
(c)
Section of
skin
Free nerve
endings
Epithelial
cells
Sensory (afferent)
nerve fiber
Epithelial
cells
Tactile
(Meissners)
corpuscle
(touch receptor)
Sensory (afferent)
nerve fiber
Lamellated
(Pacinian)
corpuscle
(pressure receptor)
Connective tissue
cells
Sensory (afferent)
nerve fiber
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© Ed Reschke
12
Temperature Senses
• Warm receptors
• Sensitive to temperatures above 25oC (77o F)
• Unresponsive to temperature above 45oC (113oF)
• Cold receptors
• Sensitive to temperatures between 10oC (50oF) and 20oC
(68oF)
• Pain receptors
• Respond to temperatures below 10oC
• Respond to temperatures above 45oC
13
Sense of Pain
• Pain receptors/nociceptors
• Free nerve endings
• Widely distributed
• Nervous tissue of brain lacks pain receptors
• Stimulated by tissue damage, chemical, mechanical forces, or
extremes in temperature
• Adapt very little, if at all
14
Visceral Pain
• Pain receptors are the only receptors in viscera whose
stimulation produces sensations
• Pain receptors respond differently to stimulation
• Pain receptors are not well localized
• Pain receptors may feel as if coming from some other part of
the body
• Known as referred pain…
15
Referred Pain
• May occur due to sensory impulses from two regions
following a common nerve pathway to brain
Appendix
Ureter
Lung and
diaphragm
Heart
Stomach
Pancreas
Colon
Kidney
Urinary bladder
Liver and
gallbladder
Small
intestine Ovary
(female)
Liver and
gallbladder
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16
Pain Pathways
• Acute pain fibers
• A-delta fibers
• Myelinated
• Conduct impulses rapidly
• Associated with sharp pain
• Well localized
• Chronic pain fibers
• C fibers
• Unmyelinated
• Conduct impulses more
slowly
• Associated with dull,
aching pain
• Difficult to pinpoint
• Blocked by narcotics
(controlled substances)
• CCC (Chronic, C fibers,
Controlled substances)
17
Regulation of Pain Impulses
• Thalamus
• Allows person to be aware of pain
• Cerebral cortex
• Judges intensity of pain
• Locates source of pain
• Produces emotional and motor responses to pain
• Pain inhibiting substances:
• Enkephalins
• Serotonin
• Endorphins
19
Proprioception
• Mechanoreceptors
• Send information to spinal cord and CNS about body
position and length, and tension of muscles
• Main kinds of proprioceptors:
• Pacinian corpuscles – in joints
• Muscle spindles – in skeletal muscles*
• Golgi tendon organs – in tendons*
*considered to be stretch receptors
20
Stretch Receptors
(a)
Muscle spindle Skeletal muscle fiber
Golgi tendon organ
Tendon
(b)
Sensory
(afferent)
nerve fiber
Sensory
nerve endings
Sensory
(afferent)
nerve fiber
Connective
tissue sheath
Intrafusal
fiber
Skeletal muscle
fiber
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21
Visceral Senses
• Receptors in internal organs
• Convey information that includes the sense of
fullness after eating a meal as well as the
discomfort of intestinal gas and the pain that
signals a heart attack
23
12.4: Special Senses
• Sensory receptors are within large,
complex sensory organs in the head
• Smell in olfactory organs
• Taste in taste buds
• Hearing and equilibrium in ears
• Sight in eyes
24
12.2 Clinical Application
Mixed-Up Senses: Synesthesia
http://www.youtube.com/watch?v=FTr1VnXKr4A
25
Sense of Smell
• Olfactory receptors
• Chemoreceptors
• Respond to chemicals dissolved in liquids
• Olfactory organs
• Contain olfactory receptor cells and supporting epithelial
cells
• Cover parts of nasal cavity, superior nasal conchae, and a
portion of the nasal septum
26
Olfactory Receptors
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Nasal cavity
Cilia
(b) (a)
Cribriform
plate
Olfactory area of
nasal cavity
Superior nasal
concha
Olfactory
bulb
Olfactory
tract
Nerve fibers within
the olfactory bulb
Olfactory
receptor cells
Columnar
epithelial cells Cribriform
plate
27
Olfactory Nerve Pathways
• Once olfactory receptors are stimulated, nerve impulses
travel through openings in cribiform plates
• Olfactory nerves olfactory bulbs olfactory
tracts limbic system (for emotions) and olfactory
cortex (for interpretation)
28
Olfactory Stimulation
• Olfactory code
• Hypothesis
• Odor that is stimulated by a distinct set of receptor cells and
its associated receptor proteins
• Olfactory organs located high in the nasal cavity above the
usual pathway of inhaled air
• Olfactory receptors undergo sensory adaptation rapidly
• Sense of smell drops by 50% within a second after
stimulation
29
Sense of Taste
• Taste buds
• Organs of taste
• Located on papillae of tongue, roof of mouth, linings of
cheeks and walls of pharynx
• Taste receptors
• Chemoreceptors
• Taste cells – modified epithelial cells that function as
receptors
• Taste hairs –microvilli that protrude from taste cells through
pores of taste buds; sensitive parts of taste cells
30
Taste Receptors
Papillae
(a)
(b)
Connective
tissue
Sensory (afferent)
nerve fibers
Epithelium
of tongue
Supporting
cell
Taste
pore
Taste hair
Taste cell
Taste buds
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31
Taste Sensations
• Five primary taste sensations
• Sweet - stimulated by carbohydrates
• Sour - stimulated by acids
• Salty - stimulated by salts
• Bitter - stimulated by many organic compounds
• Umami – stimulated by some amino acids
• Spicy foods activate pain receptors
• Taste receptors undergo rapid adaptation
32
Taste Nerve Pathways
• Sensory impulses from taste receptors travel along:
• Cranial nerves VII, IX, and X to…
• Medulla oblongata to…
• Thalamus to…
• Gustatory cortex (for interpretation)
33
12.3 Clinical Application
Smell and Taste Disorders
http://www.youtube.com/watch?v=Dm1YahV5JeE
The Importance of Olfaction
Beyond Smell
&
Memory and Smell
34
http://www.youtube.com/watch?v=R-TTHK40u4w
http://www.youtube.com/watch?v=8ybA6SScQ8A
35
Sense of Hearing
• Ear
• Organ of hearing
• Three (3) sections:
• Outer/External ear
• Middle ear
• Inner/Internal ear
36
External Ear
• Auricle
• Collects sounds
waves
• External acoustic meatus
• Lined with
ceruminous glands
• Carries sound to
tympanic membrane
• Terminates with
tympanic membrane
• Tympanic membrane
• Vibrates in response
to sound waves
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Round window
Pharynx Auditory tube
Auricle
Oval window
(under stapes)
Cochlea
Malleus
Incus Stapes
External acoustic
meatus
Semicircular
canals
Vestibulocochlear
nerve
Tympanic cavity
Tympanic
membrane
37
Middle Ear
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Round window
Pharynx Auditory tube
Auricle
Oval window
(under stapes)
Cochlea
Malleus
Incus Stapes
External acoustic
meatus
Semicircular
canals
Vestibulocochlear
nerve
Tympanic cavity
Tympanic
membrane
• Tympanic cavity
• Air-filled space in
temporal bone
• Auditory ossicles
• Vibrate in response to
tympanic membrane
• Malleus, incus and stapes
• Hammer, anvil and stirrup
• Oval window
• Opening in wall of tympanic
cavity
• Stapes vibrates against it to
move fluids in inner ear
• Tympanic Reflex
• Muscle contractions that occur during loud sounds to tighten bridge of
auditory ossicles
• Muscles involved are tensor tympani and stapedius
38
Middle Ear
Temporal
bone
Malleus
Incus
Tympanic
cavity
Tendon of
stapedius m.
Stapes
Tympanic
membrane
(a)
Auditory
tube
Round
window
Oval window
Tensor tympani m.
Tendon of
tensor tympani m.
Stapedius m.
Stapedius
tendon
Stapes
Incus
(b)
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39
Auditory Tube
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Round window
Pharynx Auditory tube
Auricle
Oval window
(under stapes)
Cochlea
Malleus
Incus Stapes
External acoustic
meatus
Semicircular
canals
Vestibulocochlear
nerve
Tympanic cavity
Tympanic
membrane
• Also known as the
eustachian tube
• Connects middle ear to
throat
• Helps maintain equal
pressure on both sides of
tympanic membrane
• Usually closed by valve-
like flaps in throat
Inner Ear
• Complex system of
labyrinths
• Osseous labyrinth
• Bony canal in
temporal bone
• Filled with
perilymph
• Membranous labyrinth
• Tube within osseous
labyrinth
• Filled with
endolymph
Cochlear nerve
Maculae
Utricle
(a)
Cochlea
Saccule
Ampullae
Endolymph
Perilymph
Membranous
labyrinth
Bony labyrinth
Vestibular nerve
Scala
vestibuli (cut)
Scala
tympani (cut)
Cochlear
duct (cut)
containing
endolymph
Vestibule Oval
window
Round
window
Semicircular
canals
Bony labyrinth
(contains perilymph)
Membranous labyrinth
(contains endolymph)
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40
Inner Ear
Cochlear nerve
Maculae
Utricle
(a)
Cochlea
Saccule
Ampullae
Endolymph
Perilymph
Membranous
labyrinth
Bony labyrinth
Vestibular nerve
Scala
vestibuli (cut)
Scala
tympani (cut)
Cochlear
duct (cut)
containing
endolymph
Vestibule Oval
window
Round
window
Semicircular
canals
Bony labyrinth
(contains perilymph)
Membranous labyrinth
(contains endolymph)
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41
• Three (3) parts of labyrinths:
• Cochlea
• Functions in hearing
• Semicircular canals
• Functions in
equilibrium
• Vestibule
• Functions in
equilibrium
42
Cochlea
• Scala vestibuli
• Upper compartment
• Leads from oval
window to apex of
spiral
• Part of bony labyrinth
• Scala tympani
• Lower compartment
• Extends from apex of
the cochlea to round
window
• Part of bony labyrinth
Stapes vibrating in
oval window
Scala vestibuli
filled with perilymph
Vestibular
membrane
Basilar
membrane
Scala tympani
filled with
perilymph
Round window
Helicotrema
Membranous
labyrinth
Cochlear duct
filled with endolymph
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43
Cochlea
• Cochlear duct
• Portion of membranous
labyrinth in cochlea
• Vestibular membrane
• Separates cochlear duct
from scala vestibuli
• Basilar membrane
• Separates cochlear duct
from scala tympani
•Tectorial membrane
• Extends partially into
cochlear duct
Spiral organ (organ of Corti)
Basilar membrane
(a)
Scala vestibuli
(contains perilymph)
Vestibular membrane
Cochlear duct
(contains endolymph)
Scala tympani
(contains perilymph)
Branch of
cochlear
nerve
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44
Getting a Cochlear Implant
http://www.youtube.com/watch?v=GTKMJ-El0sA
Cochlea
45
Spiral Organ (Organ of Corti)
• Group of hearing receptor cells (hair
cells)
• On upper surface of basilar
membrane, just below tectorial
membrane
• Different frequencies of vibration
move different parts of basilar
membrane
• Particular sound frequencies cause
hairs of receptor cells to bend as they
push up against the tectorial
membrane
• Nerve impulse generated
Spiral organ (organ of Corti)
Hair cells
Basilar membrane
(a)
(b)
Scala vestibuli
(contains perilymph)
Cochlear duct
(contains endolymph)
Scala tympani
(contains perilymph)
Branch of
cochlear
nerve
Tectorial
membrane
Basilar
membrane
Supporting
cells
Nerve
fibers
Branch of
cochlear nerve
Vestibular membrane
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46
Spiral Organ (Organ of Corti)
Cochlear duct
Scala tympani Hair cells
(a)
(b)
Basilar
membrane
Tectorial membrane
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a: © John D. Cunningham/Visuals Unlimited; b: © Fred Hossler/Visuals Unlimited
47
Spiral Organ (Organ of Corti) Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Vestibular
membrane
Malleus Incus
Stapes
Cochlear duct
(endolymph)
Tectorial
membrane
Facial nerve
Oval window
Tympanic
membrane
Tympanic
cavity
Round
window
20,000 cps 1,500 cps 500 cps 20 cps
Receptors
(hair cells)
Scala vestibuli (perilymph)
Scala tympani (perilymph)
48
Auditory Pathways
Midbrain
Pons
Thalamus
Auditory cortex
(temporal lobe)
Medial geniculate
body of thalamus
Superior
olivary
nucleus
Medulla
oblongata
Vestibulocochlear
nerve
Cochlear
nuclei
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51
Sense of Equilibrium
• Static equilibrium
• Vestibule
• Senses position of
head when body is not
moving
• Dynamic Equilibrium
• Semicircular canals
• Senses rotation and
movement of head and
body
52
Static Equilibrium
• Macula
• Organ of static
equilibrium
• Hair cells and support
cells in wall of utricle
and saccule
• Utricle and saccule
are portions of the
membranous labyrinth
of the vestibule
• Saccule
Utricle Cochlea
Maculae
Ampullae of
semicircular
canals
Vestibulocochlear
nerve
Cochlear
duct
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Vestibule
Macula
• Macula has hair cells
embedded in gelatinous
material filled with
otoliths
• Gravity pulls on
gelatinous mass
• Bending of hairs
results in generation of
nerve impulse
Hair cells
Sensory (afferent) nerve fiber Supporting cells
Otoliths
(a) Head upright (b) Head bent forward
Macula
of utricle
Hairs of
hair cells bend
Gelatinous
material sags
Gravitational
force
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53
54
Dynamic Equilibrium
• Three (3) canals at right angles
• Ampulla
• Swelling of membranous
labyrinth that communicates with
the vestibule
• Crista ampullaris
• Sensory organ for dynamic
equilibrium
• Hair cells and supporting cells
• Located in ampulla of each
semicircular canal
• Consists of hair cells whose hairs
extend upward into dome-saped
gelatinous mass (cupula)
• Rapid turns of head or body
stimulate hair cells
• Nerve impulse
Saccule
Utricle Cochlea
Maculae
Ampullae of
semicircular
canals
Vestibulocochlear
nerve
Cochlear
duct
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Vestibule
55
Crista Ampullaris
Hair cell
Supporting cells
Sensory (afferent)
nerve fibers
Hairs
Cupula Crista
ampullaris
(a) Head in still position
(b) Head rotating
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(c)
Crista ampullaris
Semicircular canal
Endolymph
Ampulla
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Eyelid
• Palpebra
• Composed of four (4) layers:
• Skin
• Muscle
• Connective tissue
• Conjunctiva
• Orbicularis oculi – closes eyelid
• Levator palpebrae superioris –
opens eyelid
• Tarsal glands – secrete oil onto
eyelashes
• Conjunctiva – mucous
membrane; lines eyelid and covers
portion of eyeball
Eyelash
Cornea
Conjunctiva
Eyelid
Tendon of levator
palpebrae superioris
Superior
rectus
Orbicularis
oculi
Inferior
rectus
Tarsal glands
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57
Lacrimal Apparatus
• Lacrimal gland
• Lateral to eye
• Secretes tears
• Canaliculi
• Collect tears
• Lacrimal sac
• Collects from
canaliculi
• Nasolacrimal duct
• Collects from lacrimal
sac
• Empties tears into nasal
cavity
Lacrimal gland
Lacrimal sac
Superior and
inferior canaliculi
Nasolacrimal
duct
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58
Extrinsic Eye Muscles
Inferior rectus Inferior oblique
Medial
rectus
Superior
rectus
Superior
oblique
Lateral
rectus
(cut)
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• Superior rectus
• Rotates eye up and
medially
• Inferior rectus
• Rotates eye down
and medially
• Medial rectus
• Rotates eye
medially
59
Extrinsic Eye Muscles
Inferior rectus Inferior oblique
Medial
rectus
Superior
rectus
Superior
oblique
Lateral
rectus
(cut)
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• Lateral rectus
• Rotates eye
laterally
• Superior oblique
• Rotates eye down
and laterally
• Inferior oblique
• Rotates eye up and
laterally
60
61
Structure of the Eye
• Hollow
• Spherical
• Wall has three (3) layers:
•Outer fibrous tunic
•Middle vascular tunic
•Inner nervous tunic
Ciliary body Retina
Choroid coat
Sclera
Fovea centralis
Optic nerve
Lens
Iris
Pupil
Cornea
Lateral rectus
Medial rectus
Optic disc
Posterior cavity
Vitreous humor
Posterior
chamber
Anterior
chamber
Aqueous
humor
Suspensory
ligaments
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Anterior
cavity
62
Outer Tunic
Ciliary body Retina
Choroid coat
Sclera
Fovea centralis
Optic nerve
Lens
Iris
Pupil
Cornea
Lateral rectus
Medial rectus
Optic disc
Posterior cavity
Vitreous humor
Posterior
chamber
Anterior
chamber
Aqueous
humor
Suspensory
ligaments
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Anterior
cavity
• Cornea
• Anterior portion
• Transparent
• Light transmission
• Light refraction
• Sclera
• Posterior portion
• Opaque
• Protection
• Pierced by optic nerve
and blood vessels
63
Middle Tunic
Ciliary body Retina
Choroid coat
Sclera
Fovea centralis
Optic nerve
Lens
Iris
Pupil
Cornea
Lateral rectus
Medial rectus
Optic disc
Posterior cavity
Vitreous humor
Posterior
chamber
Anterior
chamber
Aqueous
humor
Suspensory
ligaments
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Anterior
cavity
• Iris
• Anterior portion
• In front of lens
• Pigmented
• Controls light intensity
• Ciliary body
• Anterior portion
• Pigmented
• Holds lens
• Moves lens for focusing
• Choroid coat
• Provides blood supply
• Contains melanocytes
• Pigments absorb extra light
64
Anterior Portion of Eye
• Filled with aqueous humor
Conjunctiva
Iris
Lens
Ciliary process
Ciliary muscles
Sclera
Cornea Anterior chamber
Vitreous
humor
Suspensory
ligaments
Posterior
chamber
Ciliary
body
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65
Lens
Conjunctiva
Iris
Lens
Ciliary process
Ciliary muscles
Sclera
Cornea Anterior chamber
Vitreous
humor
Suspensory
ligaments
Posterior
chamber
Ciliary
body
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Transparent, Biconvex , Lies behind iris, Composed of lens fibers,
Elastic, Held in place by suspensory ligaments of ciliary body
66
Ciliary Body
• Forms internal ring around the front of the eye
• Ciliary processes – radiating folds
• Ciliary muscles – contract and relax to move lens
Retina
Choroid coat
Sclera
Lens
Ciliary processes
of ciliary body
Suspensory
ligaments
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67
Accommodation
• Lens changes shape to view objects
(a)
Lens thick
Lens thin
(b)
Ciliary muscle
fibers contracted
Suspensory
ligaments relaxed
Ciliary muscle
fibers relaxed
Suspensory
ligaments taut
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• Lens thickens
when focusing on
close object
• Lens thins when
focusing on distant
objects
• Bright light
stimulates circular
muscles and pupil
constricts
68
Iris
Sympathetic
motor nerve
fiber
In dim light
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Radially arranged
Smooth muscle fibers
of the iris
Circularly arranged
smooth muscle fibers
of the iris
Pupil
In normal light In bright light
Parasympathetic
ganglion
Parasympathetic
motor nerve fiber
• Composed of
connective tissue and
smooth muscle
• Pupil is hole in iris
• Dim light stimulates
radial muscles and
pupil dilates
• Bright light
stimulates circular
muscles and pupil
constricts
• Amount and
distribution of
melanin helps
determine eye color
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Aqueous Humor
• Fluid in anterior cavity of eye
• Secreted by epithelium on inner surface of the ciliary body
• Provides nutrients
• Maintains shape of anterior portion of eye
• Leaves cavity through Canal of Schlemm
Sclera
Iris
Lens
Aqueous humor
Cornea
Vitreous humor
Ciliary process
Ciliary muscles
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Posterior
chamber
Ciliary
body
Scleral venous sinus
(canal of Schlemm)
Anterior
chamber
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Inner Tunic
• Retina
• Contains visual receptors
• Continuous with optic nerve
• Ends just behind margin of the ciliary body
• Composed of several layers
• Macula lutea – yellowish spot in retina
• Fovea centralis – center of macula lutea; produces
sharpest vision
• Optic disc – blind spot; contains no visual receptors
• Vitreous humor – thick gel that holds retina flat against
choroid coat
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Posterior Cavity
• Contains vitreous humor – thick gel that holds retina flat
against choroid coat
Ciliary body
Retina
Choroid coat
Sclera
Fovea centralis
Optic nerve
Lens
Iris
Pupil
Cornea
Lateral rectus
Medial rectus
Optic disc
Posterior cavity
Vitreous humor
Posterior
chamber
Anterior
chamber
Aqueous
humor
Suspensory
ligaments
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Anterior
cavity
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Major Groups of Retinal Neurons
• Receptor cells, bipolar cells, and ganglion cells - provide pathway
for impulses triggered by photoreceptors to reach the optic nerve
• Horizontal cells and amacrine cells – modify impulses
Sclera
Receptor cells Rod
Cone
Retina Bipolar neuron
Ganglion cell
Nerve fibers
Horizontal cell
Amacrine cell
Light waves
Retinal pigment
epithelium
Pigmented
choroid
coat
Impulses
to optic
nerve
Vitreous humor
Layer of
connecting
neurons
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74
Light Refraction
• Refraction
• Bending of light
• Occurs when light waves pass at an oblique angle into
mediums of different densities
Light wave
Perpendicular line
Air
Glass
Refracted
light wave
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75
Types of Lenses
• Convex lenses cause
light waves to converge
• Concave lenses cause
light waves to diverge
Air
Glass
(a) (b) Diverging
light waves
Convex
surface
Light
wave
Converging
light waves
Concave
surface
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76
Focusing On Retina
• As light enters eye, it is refracted by:
• Convex surface of cornea
• Convex surface of lens • Image focused on retina is upside down and reversed from left
to right
Light waves
Object Cornea
Image
Retina
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77
Visual Receptors
• Rods
• Long, thin projections
• Contain light sensitive
pigment called rhodopsin
• Hundreds of times more
sensitive to light than cones
• Provide vision in dim light
• Produce colorless vision
• Produce outlines of objects
• Cones
• Short, blunt projections
• Contain light sensitive
pigments called
erythrolabe, chlorolabe, and
cyanolabe
• Provide vision in bright
light
• Produce sharp images
• Produce color vision
• Fovea centralis contains
just cones
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Rods and Cones
Cones Rods
Rod
Cone
(c)
Many sensory (afferent)
nerve fibers
(b)
Single sensory
(afferent) nerve fiber
(a)
Retinal
pigment
epithelium
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c: © Frank S. Werblin, PhD.
79
12.6 Clinical Application
Refraction Disorders
• Concave lens corrects
nearsightedness
• Convex lens corrects
farsightedness
Light waves
Light waves
Light waves
Cornea Lens
Retina
(a) Eye too long (myopia)
(b) Normal eye
(c) Eye too short (hyperopia)
Point
of focus
Point
of focus
Point
of focus
Light waves
Concave lens
Convex lens
(a)
(b)
Uncorrected
point of focus
Corrected
point of focus
Uncorrected
point of focus
Corrected
point of focus
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80
Visual Pigments
• Rhodopsin
• Light-sensitive pigment in rods
• Decomposes in presence of light
• Triggers a complex series of
reactions that initiate nerve
impulses
• Impulses travel along optic nerve
• Pigments on cones
• Each set contains different light-
sensitive pigment
• Each set is sensitive to different
wavelengths
• Color perceived depends on
which sets of cones are stimulated
• Erythrolabe – responds to red
• Chlorolabe – responds to green
• Cyanolabe – responds to blue
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Rod Cells
Mitochondria
Nucleus
Discs of
membrane
within cell
Synaptic
ending
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82
Stereoscopic Vision
• Provides perception of distance and depth
• Results from formation of two slightly different retinal images
Light
waves
Right eye Left eye
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83
Visual Nerve Pathway
Optic tract
Eye
Fibers from
nasal (medial) half
of each retina
crossing over
Visual cortex of
occipital lobe
Lateral
geniculate
body of
thalamus
Optic
chiasma
Optic
nerve
Optic
radiations
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84
12.5: Lifespan Changes
• Age related hearing loss due to:
• Damage of hair cells in organ of Corti
• Degeneration of nerve pathways to the brain
• Tinnitus
• Age-related visual problems include:
• Dry eyes
• Floaters (crystals in vitreous humor)
• Loss of elasticity of lens, decreasing accommodation
• Glaucoma
• Cataracts
• Macular degeneration
•Age related smell and taste problems due to:
• Loss of olfactory receptors
85
Important Points in Chapter 12:
Outcomes to be Assessed
12.1: Introduction
Differentiate between general senses and special senses.
12.2: Receptors, Sensation, and Perception
Name the five types of receptors and state the function of each.
Explain how receptors trigger sensory impulses.
Explain sensation and adaptation.
12.3: General Senses
Describe the differences among receptors associated with the senses
of touch, pressure, temperature, and pain.
Describe how the sensation of pain is produced.
Explain the importance of stretch receptors in muscles and tendons.
86
Important Points in Chapter 12:
Outcomes to be Assessed
12.4: Special Senses
Explain the relationship between the senses of smell and taste.
Describe how the sensations of smell and taste are produced and
interpreted.
Name the parts of the ear and explain the function of each part.
Distinguish between static and dynamic equilibrium.
Describe the roles of the accessory organs to the eye.
Name the parts of the eye and explain the function of each part.
Explain how the eye refracts light.
Explain how the brain perceives depth and distance.
Explain the visual nerve pathways.
12.5: Life-Span Changes
Describe aging-associated changes that diminish the senses.
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