“Second Workshop on:

Postgenomics of psychiatric diseases:

imaging, genes and endogenous retroviruses

SCIENTIFIC RESPONSABLES

Simona GAUDI Department of MIPI, Istituto Superiore di Sanità, Rome(Tel. 06 49902218; e-mail: simona.gaudi@iss.it)

Fabio MACCIARDIUniversity of California Irvine, USA.(Tel. +1 949 351 4756; e-mail: fmacciard@uci.edu)

Giovanni REZZADepartment of MIPI, Istituto Superiore di Sanità, Rome(Tel.06 49906125; e-mail: giovanni.rezza@iss.it)

SCIENTIFIC SECRETARIAT

Simona GAUDI Department of MIPI, Istituto Superiore di Sanità, Rome (Tel. 06 49902218; Fax 06 49902827; e-mail: simona.gaudi@iss.it)

ORGANIZING SECRETARIAT

Alessia CARATELLI Department of MIPI, Istituto Superiore di Sanità, Rome(Tel. 06 49903205; Fax 06 49902813; e-mail: alessia.caratelli@iss.it)

Veronica BIZZOTTIDaniela CASALEValentina CECCHETTIDebora LEPORESimonetta RASIDepartment of MIPI, Istituto Superiore di Sanità(Tel. 06 49903225, 3280, 3281; Fax 06 49902813; e-mail: sgp.mipi@iss.it)

GENERAL INFORMATIONVenue: Aula Pocchiari, Istituto Superiore di Sanità Viale Regina Elena 299, Rome, Italy

PARTECIPATION CERTIFICATE At the end of the Workshop, it will be issued a participation certificate, if requested.

Official languages english and french

Editing by Valentina Cecchetti

Istituto Superiore di Sanità

Is t i tuto Super iore d i Sani tàVia le Regina Elena, 299

00161 RomaTel . +39 06 4990 1

Fax +39 06 4938 7118www.iss.it

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printed by Settore Attività Editoriali February 2011

PresidenteEnrico Garaci

organized by

Department of Infectious, Parasitic and Immune-mediated DiseasesISTITUTO SUPERIORE DI SANITÀ

Rome, February 7th 2011Aula Pocchiari

FOURTH SESSION

Chairpersons: Stefano Bonassi and Alfonso Tortorella

14.50 Euromed Network on Migration and Mental Health (E-MNMMH) and MedGENE: New Perspectives in

Psychiatry Driss Moussaoui

15.20 Integrating multi-cultural sensibilities in international clinical research: the EthiMED network

Anne Marie Duguet

15.50 Crossing the bridge: the MedGENE Simona Gaudi

16.00 Round table and discussion Giuseppe Novelli, Alfonso Tortorella, Ernesto Caffo, Alfredo Cesario, Steven Potkin, Patrick Thonneau,

Cinzia Caporale

17.00 Conclusions

February 7th 2011

09.00 Participant registration

09.30 Welcome Enrico Garaci, President of ISS

Giovanni Rezza, Director of MIPI Dept

FIRST SESSION

Chairpersons: Ernesto Caffo and Giuseppe Novelli

09.45 Postgenomics of psychiatric diseases: overview and future perspectives

Fabio Macciardi

10.15 Possible links between Fragile X mental retardation protein, Prion, Shadoo and Retroelements

Jean Luc Darlix

10.45 Custom human endogenous retroviruses dedicated microarray

Francois Mallet

11.15 Coffee break

11.45 Special Training Award Fellowship in honor of Prof. Carla Arpino

SECOND SESSION

Chairpersons: Alfredo Cesario and Fabio Macciardi

12.15 Imaging genetics of psychiatric disorders Andreas Meyer-Lindenberg

13.00 Lunch

THIRD SESSION

Chairpersons: Paola Sinibaldi Vallebona and Massimo Ciccozzi

14.00 Endogenous retroviruses and neuropsychiatric disease: the case of autism

Emanuela Balestrieri

14.20 Oxydative stress, hypoperfusion and cold chronic infections in autism

Corinne Skorupka

SPEAKERS AND CHAIRPERSONS Emanuela BALESTRIERI Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, ItalyStefano BONASSIHead, Clinical and Molecular Epidemiology, IRCCS San Raffaele Pisana, Rome, ItalyErnesto CAFFOMother and Child Department, University of Modena and Reggio Emilia, ItalyCinzia CAPORALENational Research Council (CNR), Rome, ItalyAlfredo CESARIODeputy Scientific Director, IRCCS S. Raffaele Pisana, Rome, Italy Massimo CICCOZZIDepartment of MIPI, Istituto Superiore di Sanità, Rome, ItalyJean Luc DARLIX LaboRetro, Unit of Human Virology, INSERM – Lyon, FranceAnne Marie DUGUETINSERM Unit 558, Toulouse, France Enrico GARACI President of Istituto Superiore di Sanità, Rome, Italy Simona GAUDI Department of MIPI, Istituto Superiore di Sanità, Rome, ItalyFabio MACCIARDIDepartment of Psychiatry and Human Behavior, University of California Irvine, USA Francois MALLET Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Cancer Biomarkers Research Group, Centre Hospitalier Lyon Sud, Pierre Bénite Cedex, FranceAndreas MEYER-LINDENBERG Director, Central Institute of Mental Health, Mannheim, GermanyDriss MOUSSAOUI Ibn Rushd University Psychiatric Centre in Casablanca, MoroccoGiuseppe NOVELLIUniversity of Rome Tor Vergata, ItalySteven G. POTKINDepartment of Psychiatry and Human Behavior, UCI Medical Center Brain Imaging Center - USAGiovanni REZZA Director, Department of MIPI, Istituto Superiore di Sanità, Rome, ItalyPaola SINIBALDI-VALLEBONA Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, ItalyCorinne SKORUPKAPrèsidente de l’Association Ariane Clichy, Paris, FrancePatrick THONNEAU Institute de Recherche et Development IRD, Tunis, TunisiaAlfonso A. V. TORTORELLAInstitute of Psychiatry – Medical School, University of Naples SUN, Naples- Italy

This workshop is dedicated to Carla Arpino.

Carla was a friend who loved to share with others her curiosity and her passion for science and medicine. She was also a scientist who had visions of how the research in child psychiatry should look like and how the clinical domain could be inspired by investigations on basic sciences. She strived to create a pathway to translate bench work from the lab to her daily medical activities, never tired to question herself and many others on uncountable problems that would have ultimately merged into a unified picture, that of a patient. Carla was an inspired mentor, whose goal was to promote and foster the career of young investigators who would have continued her work, and they will do so. The topics of this workshop are the final realization of many meetings and discussions that we had with Carla, when we were spending our time designing projects and trying to make sense of our observations. So, Carla is missed, but she lives in the memories of those whom she loved and in our common work that slowly realizes those ideas that we developed together.