PEOPLE COMMUNITY RESOURCES

http://www.cbni.euCentre for BioNano Interactions

Class III Cell Culture

IANH’

LOCATION FOR NEW EUINFRASTRUCTURE FOR BIONANOINTERACTIONS AND NANOSAFETY

SFI SRC, EPA, HEA

NeuroNano

Cozzarelli Prize, 2008

FP RESEARCH

Students from 14 countriesmajority funds EU internationally

26 companies from around the world

Protecting the potential for generations to come

1st reports of Nanotoxicity

Address the great intractable diseases

Cross biological barriers, e.g. blood brain barrier

Risk, investment and perception of risk Potential for radically new therapies

Watson et al. Adv Drug Delivery Rev 2005

Nanoparticles travel into cell via Existing pathways

European Parliament Members back tougher rules for nanotechnology Published: 28 April 2009

The European Parliament backed a report urging the European Commission to revise its stance on nanomaterials. MEPs said all nanomaterials should be

considered as new substances. Adopted on April 24 2009 by an overwhelming majority – 391 in favour and 3 against.

European Parliament Members Vote for Ban on Nanomaterials: Nanosilver and Carbon Nanotubes

June 16, 2010

The Members of the European Union’s (“EU”) Environment Committee (“MEPs”) voted in favor of proposed amendments to the EU’s Restriction of Hazardous

Substances Directive, banning the use of nanosilver and long multi-walled carbon nanotubes in electrical and electronic products.

By Treaty, Parliament and Commission must agree on key policy issues

Etc. ……Worldwide issues

BioNanoInteract now central EU Infrastructure for arena

Re-profiled SRC spending to capture emerging opportunities

Marie Curie Research and Training Network on Dynamical Arrest Arrested Matter – 19 Network PartnersStart date – November 2004Project Duration – 5 years (including a 1 year extension)Coordinator – University College DublinPartners – -Universita di Napoli -University of Bristol-Institute for Atomic and Molecular Physics -Harvard University-Universitat Freiburg -Universita di Messina-Universite Montpellier II -Universita di Milano-Heinrich-Heine Universitat Dusseldorf -Johannes Gutenberg Universitat Mainz-University of Edinburg-University of Fribourg-Universita di Roma-Massachusetts Institute of Technology-Institut fur Chemie, Karl Franzens Universitaet Graz -Universite du Maine, Centre National Recherche de Scientific-Instituto Nazionale de Fisica Nucleare

ARRESTED MATTER BUILT DEPTH IN NANO AND MESOSCOPIC PARTICLES

The distribution of the countries of origin of the ESR and ER are shown here:

The distribution of the ESR and ER across the partner nodes is shown here:

40nm COOH-PS NPs

APPROACHES FROMARRESTED MATTER FED INTO

RADICALLY NEW APPROACHES

MOVIE OF LIVING CELLFROM MICROSCOPE,

LEADING TO ‘SIMULATION’

Successes:• Many of the young people who took part within the framework became the young

leaders of the field- (UCD alone)de Gregorio (Prize), Foffi (Swiss national Prize EPFL, Assistant Prof), Zaccarelli (permanent position Rome, leader!) Cellai (CSET) Many other around EU.

• Coherent workshops across whole field (100 young people often) seen as the birth of the modern field in EU (we moved further into biological applications afterwards)

• Beginning of real fundamental depth in UCD in soft nanoparticle materials, and merger of experimental data with theory (see cell experiment previously)

Failures:• Not every student succeeded as planned (including some in MC program itself!). • Balance of post docs vs students (my fault) per group was imperfect (all UCD were

ESR)• Structure (committees for everything) was made overly complex, and overly heavy

in an effort to make transparent and fair in every way-my fault, well intended

SUCCESSES AND FAILURES

FP7-PEOPLE-2010-ITN

NanoTOES (Nanotechnology: Training Of Experts in Safety) – 12 Network Partners

Start date – 1st November 2010

Project Duration – 4 years

Coordinator – University of Salzburg

Partners – - Consiglio Nazionale Delle Ricerche - Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V- University College Dublin - Natural Environment Research Council - Norsk Institutt for Luftforskning - Institut Universitaire Romand De Sante Au Travail - Institute of Experimental Medicine – Hungarian Academy of Sciences- Catalan Institute of Nanotechnology- AvantiCell Science Ltd - Grimm Aerosol Technik Gmbh & Co KG Pesch - Bayer Technology Services GMBH

SOON TO STARTPARTNER

NO ONE CAN SAY HOW TO SUCCEEDPERSONAL VIEW

• Win the key step by prior results-even if it is only one key paper, make it the ‘example

• Find the best people (who know how to educate young leaders), and ask them early• But not too many (!)

• Frame the initial vision yourself, explain it carefully-show each the role they would play

• Identify the real need at EU level for such young people trained (eg Infra)

• Start early

Winning as Co ordinator

Winning as Partner

• If you are senior, easier, if more junior, ask seniors to include you-don’t by shy• Try to be a support centrally in the preparation, and execution-visibility, and experience• Start early