pan international list of highly hazardous pesticides (pan...

PAN International List of

Highly Hazardous Pesticides (PAN List of HHPs)

May 2013

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Hamburg - May 2013

PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 05/2013 2

This ‘PAN International List of Highly Hazardous Pesticides’ has been drafted by Pesticide Action Network Germany for

‘Working Group 1: Pesticides & Corporations of Pesticide Action Network International.

PAN Germany thanks the members of PAN International Working Group 1 for the constructive discussion and especially Dr. Rolf Altenburger (PAN Germany) and

Dr. Meriel Watts (PAN Aotearoa/New Zealand) for their valuable contributions.

The PAN List of HHPs was adopted by the PAN International Working Group November 2008 and by the

PAN International Regional Coordinators January 2009. The updated PAN List of HHPs 2010 was adopted by

PAN International Working Group 1 Nov./2010 and by the PAN International Regional Coordinators 12/2010. A formal

update was done by PAN Germany May 2013.

Pestizid Aktions-Netzwerk e.V. (PAN Germany) Nernstweg 32

22765 Hamburg Germany

Email: [email protected]

www.pan-international.org

Hamburg/Germany, May 2013

Authors: Lars Neumeister & Carina Weber


About this publication

For decades, the distribution and use of hazardous pesticides is an issue of concern. Since it’s founding in 1982, Pesticide Action Network (PAN) has been the civil society organization (CSO) most steadily and continuously calling for effective international action towards the elimination of hazardous pesticides. And PAN has been one of the key driving forces among non-governmental organizations (NGOs) for improving plant protection policies towards safer, socially just and economically viable pest management systems.

In 1985, the International Code of Conduct on the Distribution and Use of Pesticides was adopted by FAO to respond to the growing evidence of risks associated with the use of pesticides. Already this first version of the Code of Conduct indirectly questioned the “safe use” concept as an overall approach to solve pesticide related problems, as it says in Article 5.2.3 that industry should halt sale and recall products when handling or use pose an unacceptable risk under any use directions or restrictions. Since the 1980s a number of international instruments and guidelines have been adopted1 to tackle pesticide related problems. Additionally, many public and private initiatives have been implemented to reduce the adverse effects of pesticide use in agriculture. However, overall the initiatives have been successful only to a limited extent and the concept of a safe use of highly hazardous pesticides has been questioned increasingly by NGOs/CSOs, scientists, governmental representatives and in the private sector. Meanwhile numerous initiatives in food, forest and flower production and distribution chains resulted in black lists for specific pesticides, and inNovember 2009, the European Union with regulation 1107/2009/EC2 decided that substances proven to be carcinogenic, mutagenic, toxic for reproduction and endocrine disruptors shall not be authorized in the EU.

In November 2006 the FAO Council discussed and endorsed SAICM, the Strategic Approach to International Chemicals Safety. In view of the broad range of activities envisaged within SAICM, the Council suggested that the activities of FAO could include risk reduction, including the progressive ban on highly hazardous pesticides, promoting good agricultural practices, ensuring environmentally sound disposal of stock-piles of obsolete pesticides and capacity-building in establishing national and regional laboratories.

In April 2007 the FAO Council informed COAG3 of its intention to develop a new initiative for pesticide risk reduction. COAG welcomed the initiative to reduce risks associated with the use of hazardous pesticides including the progressive ban on highly hazardous pesticides.

In October 2007 the FAO/WHO Panel of Experts on Pesticide Management discussed the so-called thought starter “Addressing Highly Toxic Pesticides (HTPs)” with a note from the Secretariat explaining: “Through this thought-starter FAO wishes to start its work on highly 1 E.g. the Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in

International Trade (http://www.pic.int), the Stockholm Convention on Persistent Organic Pollutants (http://www.pops.int) or the Strategic Approach to International Chemicals Management (http://www.saicm.org/)

2 EC (2009a): Regulation (EC) No 1107/2009 of the European Parliament and of the Council of 21 October 2009 concerning the placing of plant protection products on the market and repealing Council Directives 79/117/EEC and 91/414/EEC. Official Journal of the European Union L 309. 24.11.2009

3 The FAO Committee on Agriculture (COAG) conducts periodic reviews and appraisals of agricultural and nutritional problems in order to propose concerted action by Member Nations and the Organization. It also reviews the agriculture and food and nutrition work programmes of the Organization and their implementation, with emphasis on the integration of all social, technical, economic, institutional and structural aspects in promoting agricultural and rural development. Its functions are enumerated in Rule XXXII of the General Rules of the Organization. Membership must be renewed formally each biennium


hazardous pesticides.” (...) “This thought-starter builds on the information document providedto COAG on pesticide risk reduction4. As a first step, this paper focuses on options for defining highly hazardous pesticides.” Based on this thought starter the Panel of Experts outlined criteria to identify highly hazardous pesticides (HHP, see Table 1). In addition, the Panel of Experts “recommended that FAO and WHO, as a first step, should prepare a list of HHPs based on the criteria identified, and update it periodically in cooperation with UNEP. It further requested that such a list should be made widely known to all stake-holders involved in pesticide regulation and management.”5

PAN strongly welcomed these decisions made by the FAO Council, the COAG and the FAO/WHO Panel of Experts on Pesticide Management. PAN was of the opinion however, that the list of indicators agreed by the Panel of Experts had some important shortcomings; in particular it is important to note that pesticides with endocrine disrupting properties, eco-toxicological properties, or inhalative toxicity have not been taken into account by the FAO/WHO Panel of Experts.

Because of these shortcomings, PAN International decided to independently develop a definition of “Highly Hazardous Pesticides” (HHPs) with a more comprehensive set of indicators and to achieve a list of HHPs based on the PAN list of indicators.

This publication describes how PAN defines Highly Hazardous Pesticides (HHPs) by identifying the indicators. An explanation of the indicators is followed by a list of HHPs on the basis of the indicators.

It is important to note that also the PAN list of HHPs presented in this publication is still not complete. There are several reasons for the limitations in completeness.

A major reason is that the indicators used for the PAN definition of HHPs are based on widely accepted classifications. Due to the time needed for achieving consented classifications these classifications do have shortcomings as explained in this publication.

Correspondingly, there are “emerged priorities” e.g. pesticides with endocrine disrupting properties. Such properties are not sufficiently operationalised for pesticides as yet.

Measures to identify substances of high environmental concern have been restricted to the application of consented criteria indicating ubiquitous environmental occurrence and hazardous properties for one ecosystem service, bees.

In addition, pesticides that may be shown to be linked with a high incidence of severe or irreversible adverse effects on human health or the environment are not identified systematically yet. On the basis of ongoing community monitoring, PAN will identify and list such highly hazardous pesticides in the future.

Experiences in the past show that pesticides being classified as “moderately hazardous” by the World Health Organization give reason for concern even though they are just classified as moderately hazardous. Examples are endosulfan and paraquat, pesticides that caused hundreds of poisonings, or pyrethrins which became known to cause various incidences in the US. However, with a view to prioritisation

4 This document is available at: http://www.fao.org/unfao/bodies/coag/coag20/index_en.htm5 The minutes of the panel of experts meeting October 2007 are available at: http://www.fao.org/agriculture/crops/core-

themes/theme/pests/code/panelcode/en/


PAN has not added WHO II ("moderately hazardous") pesticides to the list of indicators.

In order to implement a progressive ban of highly hazardous pesticides as supported by the FAO Council, the COAG, the FAO/WHO Panel of Experts for Pesticide Management and others, all stakeholders mentioned in the International Code of Conduct on the Distribution and Use of Pesticides should develop plans of action for a progressive ban of HHPs. These are governments, the pesticide industry, the food industry, farmers and farmer's organisations, and public interest groups.

This is especially important as there are currently no legal instruments available to achieve a structured and clearly targeted global progressive ban of HHPs other than the Stockholm convention for Persistent Organic Pollutants which focuses only on a very small group of HHPs.

This PAN list of HHPs provides a basis for action to implement the progressive ban of highly hazardous pesticides. PAN would like to encourage individuals, institutions, organizations and companies to develop a plan of action with priorities, timeframes and concrete measures. PAN itself will support such initiatives wherever possible.

Carina Weber / PAN Germany for PAN International Hamburg, May 2013


What is new in this edition?

Indicators based on EU Directive 65/548/EC on Classification & Labelling are replaced by the appropriate classification under the Globally Harmonized System (GHS). The HHP List is not affected by that change, because the EU classification 'translates' into the GHS (for details see the EU Regulation [1272/2008]).

Furthermore, some substances like arsen and its compounds were grouped together (see table 1), that makes the list more compact and more consistent with national and international regulations.

Table 1: List of groups and compounds Group and substances (intend) CAS NumberArsen and its coumpounds 7778-39-4

Arsenic pentoxide 1303-28-2Cacodylic acid; dimethylarsinic acid 75-60-5MSMA 2163-80-6Sodium arsenate 13464-38-5Cacolydate; sodium dimethylarsinate 124-65-2

DNOC and its salts 534-52-1DNOC ammonium salt 2980-64-5DNOC potassium salt 5787-96-2DNOC sodium salt 2312-76-7

Paraffin oils; mineral oils 64741-88-4Paraffin oil/(CAS 64741-89-5) 64741-89-5Paraffin oil/(CAS 64741-97-5) 64741-97-5Paraffin oil/(CAS 64742-46-7) 64742-46-7Paraffin oil/(CAS 64742-54-7) 64742-54-7Paraffin oil/(CAS 64742-55-8) 64742-55-8Paraffin oil/(CAS 64742-65-0) 64742-65-0Paraffin oil/(CAS 72623-86-0) 72623-86-0Paraffin oil/(CAS 97862-82-3) 97862-82-3

Mercury and its compounds 7439-97-6Mercuric chloride 7487-94-7Mercuric oxide 21908-53-2


PAN International Indicators for Identifying ‘Highly Hazardous Pesticides’

The following Table shows the criteria and sources used by PAN to identify pesticides considered to be highly hazardous according to PAN.

High acute toxicity

‘Extremely hazardous’ (Class Ia) according to WHO Recommended Classification of Pesticides by Hazard

‘Highly hazardous’ (Class Ib) according to WHO Recommended Classification of Pesticides by Hazard

‘Fatal if inhaled’ (H330) according to the Globally Harmonized System (GHS)

Long term toxic effects

Carcinogenic to humans according to IARC, US EPA or ‘Known or presumed human carcinogens’ (Category I) according to the Globally Harmonized System (GHS)

Probable/likely carcinogenic to humans according to IARC, US EPA

Possible human carcinogen/ Suggestive evidence of carcinogenic potential according to IARC, US EPA or 'Suspected human carcinogen’ (Category 2) according to the Globally Harmonized System (GHS)

'Substances known to induce heritable mutations or to be regarded as if they induce heritable mutations in the germ cells of humans’, ‘Substances known to induce heritable mutations in the germ cells of humans’ (Category I) according to the Globally Harmonized System (GHS)

'Known or Presumed human reproductive toxicant' (Category I) according to the Globally Harmonized System (GHS)

Endocrine disruptor

‘Suspected human reproductive toxicant’ (Category 2) AND ‘Suspected human carcinogen’ (Category 2) according to the Globally Harmonized System (GHS)

potential endocrine disruptor according to EU Category 1 and Category 2

High environmental concern

Pesticides listed in Annex A & B of the Stockholm ConventionOzone depleting according to the Montreal Protocol

‘Very bioaccumulative’ according to REACh (BCF >5000)

‘Very persistent’ according to REACh (half-life > 60 d in marine- or freshwater or half-life > 180 d in marine or freshwater sediment)

Hazard to ecosystem services

‘Highly toxic for bees’ according to U.S. EPA (LD50, µg/bee < 2)

Known to cause a high incidence of severe or irreversible adverse effects

Pesticides listed in Annex III of the Rotterdam Convention


Explanatory notes and comments regarding the classification systems, lists and indicators being used by PAN to identify Highly Hazardous Pesticides

The Globally Harmonised System of Classification and Labelling of Chemicals (GHS) The aim of the GHS is a global harmonization of the classification and labeling of chemicals. The Plan of Implementation of the World Summit on Sustainable Development (WSSD), adopted in Johannesburg in 2002, encourages countries to implement the GHS as soon as possible with a view to having the system fully operational by 2008. However, on global scale it has not been fully implemented yet. The European Union already started to convert its classification and labeling system (Directives 67/548/EC and 1999/45/EC) to the GHS system (Regulation 1272/2008/EC). By 2015 the older Directive will be replaced, until then both systems will exist in parallel.

Since the GHS classification has not been established on a global scale PAN International applies the EU GHS (Regulation 1272/2008/EC and its amendments) for the development of the List of HHPs.

The WHO Recommended Classification of Pesticides by Hazard The latest revision of the WHO Recommended Classification of Pesticides by Hazards was conducted in 2009 and contains about 870 pesticides. PAN included those pesticides listed in WHO Class Ia and Ib into the PAN HHP list.

The most recent version of the WHO classification must be considered incomplete for the following reasons: - Since the last revision a large number of new active ingredients entered market, but their hazards have not been classified by WHO. - LD50 values for inhalative toxicity are not included in the WHO classification. This is a major deficiency because users of pesticides are often exposed via inhalation. - Endocrine disruption is not included in the WHO classification. - Formulations are not included in the classification. The acute toxicity of formulations and mixtures can be calculated based on the percentage and the LD50 values of the active ingredients in the formulation or mixture. However, so-called ‘inert’ ingredients or solvents6

are neglected in this calculation although they may have an influence on the toxicity of the formulation or the mixture.

Source used: WHO (2010): The WHO recommended classification of pesticides by hazard and guidelines to classification 2009, International Program on Chemical Safety (IPCS) & World Health Organization (WHO), Geneva.

6 “Inert” ingredient: substances which can enhance the efficiency of the active substance, make a product more degradable or

easier to use. ‘Inerts’ are mostly handled as trade secrets of the manufacturer, which means they are not labelled on the product and therefore not included in the calculation.


Regulation 1272/2008/EC – EU GHS The new EU Regulation1272/2008/EC on classification, labelling and packaging of substances and mixtures entered into force in January 2009. It implements the Globally Harmonised System (GHS).

Classification and labelling of chemicals according to EU Regulation1272/2008/EC follows very similar criteria as Council Directive 67/548/EC, but uses instead of danger symbols new pictograms and instead of Risk and Safety phrases Hazard Statements and Precautionary Statements, respectively.

PAN uses EU Regulation1272/2008/EC and it’s amendments complimentary to Directive 67/548/EC to identify pesticides which are considered highly toxic via inhalation, carcinogenic, mutagenic and/or toxic to reproduction.

Sources used: EC (2008): Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Official Journal of the European Union L 353/1 EC (2009): Commission Regulation 790/2009 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labeling and packaging of substances and mixtures. Official Journal of the European Union L 235/1

REACh REACh, the ‘Registration, Evaluation, Authorisation and Restriction of Chemicals’ is aEuropean Union Regulation (EC/2006/1907 of 18 December 2006). It addresses the production and use of chemical substances, and their potential impacts on both human health and the environment. REACH applies to all chemicals imported or produced in the EU.

The Technical Guidance Document7 on risk assessment defines the criteria for persistence and bioaccumulation, which are used for the PAN list of HHP.

According to REACh chemicals are “very bioaccumulative” if their Bio-Concentration Factor (BCF) is larger than 5,000 and “very persistent” if their half-life in marine water or fresh water exceeds 60 days or their half-life in marine or freshwater sediment exceeds 180 days.

Source used: ECB (2003): Technical Guidance Document on Risk Assessment in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for existing substances Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market. Part II. Institute for Health and Consumer Protection. European Chemicals Bureau (ECB)

7 ECB (2003): Technical Guidance Document on Risk Assessment in support of Commission Directive

93/67/EEC on Risk Assessment for new notified substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for existing substances Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market. Part II. Institute for Health and Consumer Protection. European Chemicals Bureau (ECB)


International Agency for Research on Cancer (IARC) The International Agency for Research on Cancer (IARC) is part of the World Health Organisation (WHO). The goal of IARC is to evaluate, with the assistance of international working groups of experts, critical reviews and evaluations of evidence of carcinogenicity and to publish them in monographs. This series of monographs started in 1972 and since then, almost 900 agents have been reviewed. Participants in the working groups are individual scientists who do not represent organisations, industry or governments.

All pesticides which are classified as ‘carcinogenic to humans’ (Group 1), ‘probably carcinogenic to humans’ (Group 2A) or ‘possibly carcinogenic to humans’ (Group 2B) have been included in the PAN List of HHPs.

Source used: IARC (2006): Agents reviews by the IARC Monographs, Volumes 1-95 (by CAS Numbers), International Agency for Research on Cancer (IARC), Lion, France. Website: http://monographs.iarc.fr/index.php

U.S. Environmental Protection Agency (U.S. EPA) The U.S. EPA Office of Pesticide Programs maintains a List of Chemicals Evaluated for Car-cinogenic Potential8. This list is a product of the general risk assessment included in the process of pesticide registration. This classification can be seen as a further development of the IARC classification system, but also includes the potential exposure of humans9.Therefore, a low exposure potential can place a pesticide in a lower category even when sufficient evidence of carcinogenicity exists. U.S. EPA's classification of carcinogenicity has changed several times over the last 20 years. The list is updated annually, but its focus is mostly on pesticides registered in the USA.

Source used: US EPA (2012): Chemicals Evaluated for Carcinogenic Potential, November 2012, Science Information Management Branch, Health Effects Division, Office of Pesticide Programs U.S. Environmental Protection Agency (US EPA), Washington DC, USA

Classification for bee toxicity The US EPA also defines categories for environmental toxicity of pesticides10. US EPA defines a pesticide as highly toxic to bees if the LD 50 is lower that 2 microgram/bee (µg/bee). Pesticides highly toxic to bees are included in the PAN List of HHP.

8 US EPA (2012): Chemicals Evaluated for Carcinogenic Potential, November 2012, Science Information Management

Branch, Health Effects Division, Office of Pesticide Programs U.S. Environmental Protection Agency (US EPA), Washington DC, USA

9 Altenburger, R., Bödeker, W., Brückmann, S., Oetken, G., Weber, C. (1999): Zur Human- und Ökotoxizität von Pestiziden, die im Bananenanbau verwendet werden, Pestizid Aktions-Netzwerk e.V. (PAN Germany), Hamburg, Germany

10 US EPA (2013): Technical Overview of Ecological Risk Assessment Analysis Phase: Ecological Effects Characterization, U.S. Environmental Protection Agency, Washington, DC www.epa.gov/oppefed1/ecorisk_ders/toera_analysis_eco.htm


EU categorization of endocrine disruptors The issue of endocrine disrupting pesticides gained widespread public, political andscientific attention at the beginning of the 1990s. Today there are still no confirmed lists of pesticides with endocrine disrupting properties on any official national or international level (e.g. EU, WHO). However, the EU has developed a priority list of pesticides with evidence for endocrine disrupting properties.

In the PAN list of HHPs all EU Category 1 pesticides (at least one study providing evidence of endocrine disruption in an intact organism) and Category 2 pesticides (in vitro evidence of endocrine disruption) are included.

With Regulation 1107/2009/EC the European Union decided to exclude pesticide active ingredients from EU authorization, which have endocrine disrupting properties that may cause adverse effects in humans. By 14 December 2013, the European Commission shall present a draft of the measures concerning specific scientific criteria for the determination of endocrine disrupting properties. Pending the adoption of these criteria, substances that are or have to be classified, in accordance with the provisions of Regulation (EC) No 1272/2008, as carcinogenic category 2 and toxic for reproduction category 2, shall be considered to have endocrine disrupting properties (EC 2009a).

PAN International applies these preliminary criteria for the identification of endocrine disrupting chemicals and included pesticide which are classified in Regulation 1272/2008/EC as carcinogenic category 2 and toxic for reproduction category 2 as endocrine disruptors.

Sources used: EC (2000): Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption - preparation of a candidate list of substances as a basis for priority setting, European Commission, Delft EC (2004): Commission Staff Working Document SEC (2004) 1372 on implementation of the Community Strategy for Endocrine Disrupters - a range of substances suspected of interfering with the hormone systems of humans and wildlife (COM (1999) 706), European Commission, Brussels EC (2007): Commission staff working document on the implementation of the "Community Strategy for Endocrine Disrupters" - a range of substances suspected of interfering with the hormone systems of humans and wildlife (COM (1999) 706), (COM (2001) 262) and (SEC (2004) 1372). SEC(2007) 1635. European Commission (EC).Brussels, 30.11.2007 EC (2008): Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Official Journal of the European Union L 353/1 EC (2009a): Regulation (EC) No 1107/2009 of the European Parliament and of the Council of 21 October 2009 concerning the placing of plant protection products on the market and repealing Council Directives 79/117/EEC and 91/414/EEC. Official Journal of the European Union L 309. 24.11.2009 EC (2009b): Commission Regulation 790/2009 amending, for the purposes of its adaptation to technical and scientific progress, Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labeling and packaging of substances and mixtures. Official Journal of the European Union L 235/1


International Conventions & Treaties on chemicals of high concern The Stockholm Convention aims at the elimination of Persistent Organic Pollutants (POPs), some of the most unwanted chemicals in the world. POPs are toxic, bioaccumulative, highly persistent, capable of long-range transport and pose a global threat to living beings, especially in the Arctic region where they biomagnify. All pesticides formally adopted under these criteria to the Stockholm Convention are on the PAN HHP list.

The Rotterdam Convention on the Prior Informed Consent (PIC) Procedure for Certain Hazardous Chemicals and Pesticides in International Trade regulates the exchange of information in international trade in certain hazardous pesticides (active ingredients and formulations). All pesticides formally adopted under the Rotterdam Convention are on the PAN list of HHP.

Certain pesticide formulations are included in Annex 3 of the Rotterdam Convention. It is important to note that these active ingredients are on the PAN list even though they are regulated only in specific formulations. These active ingredients are marked in the attachment.

The Montreal Protocol on Substances that Deplete the Ozone Layer is an international treaty designed to protect the ozone layer by phasing out the production of a number of substances believed to be responsible for ozone depletion. Currently, there is one pesticide listed as ozone depleting chemical. This pesticide (methyl bromide) is on the PAN list of HHP.

Sources used: Website of the Stockholm Convention at http://www.pops.intWebsite of the Rotterdam Convention at http://www.pic.int Website of Montreal Protocol at http://ozone.unep.org/

Ecosystem services – pollination by bees The U.S. EPA Office of Pesticide Programs after reviewing individual toxicity or ecological effect studies for a pesticide summarizes the toxicity to certain species groups. In developing its ecological effect characterization, EPA uses a three-step scale of toxicity categories to classify pesticides based on bee toxicity data. All pesticides classified as ‘highly toxic to bees’ have been included to the HHP list by PAN. Source used: FOOTPRINT (2012): The FOOTPRINT Pesticide Properties DataBase. Database collated by the University of Hertfordshire as part of the EU-funded FOOTPRINT project (FP6-SSP-022704) (http://www.eu-footprint.org).

Method applied to identify highly hazardous pesticides The classification systems and lists mentioned above have been integrated in a relational pesticide database consisting of numerous tables representing the classification systems and lists Matching fields between the tables are either CAS numbers or unique identification numbers (IDs). Data were usually imported from Excel, Access or PDF files. A table (list) of all pesticides is linked to all tables containing classification systems and lists mentioned above, and this table/list was searched for the criteria defining highly hazardous pesticides. Pesticides which are considered to be ‘obsolete’ by the WHO/IPCS were omitted from the search, if they are not targeted by


any of the international conventions (Rotterdam Convention/PIC pesticides), Stockholm Convention/POP pesticides).

The FOOTPRINT Pesticide Properties Database has been used to identify pesticides with the characteristics of being persistent, bioaccumulative and/or toxic to bees (LD50 <2 microgram/bee).

Evolution of the PAN List of Highly Hazardous Pesticides This updated PAN International List of Highly Hazardous Pesticides is longer than the 1st version of the list dated January 16th, 2009, but shorter than the version from 2011. In 2010 more pesticides were classified as toxic to bees and as persistent. In 2013, numerous substances, which are not-agricultural pesticides or obsolete, were deleted.

Newly added pesticides since January 2009 2009-2011

Alanycarb Amidosulfuron Asulam, sodium salt Benfuracarb Bensulide beta-HCH; beta-BCH Bioresmethrin Blasticidin-S Borax; disodium tetraborate decahydrate Boric acid Carbosulfan Chlordimeform Chlorphropham Clopyralid Cyhalothrin Cyhalothrin, gamma Diafenthiuron Dimefuron Dimoxystrobin Dinotefuran Diquat dichloride Dithianon E-Phosphamidon EPTC Ethaboxam Ethirimol Fenchlorazole-ethyl Fenothiocarb Fenpropidin Flufenoxuron Glufosinate-ammonium Lenacil Metazachlor Metobromuron Metoxuron Metsulfuron-methyl Milbemectin Naled Napropamide Nicosulfuron Nitenpyram Nitrobenzene Oxycarboxin

Penconazole Pentachlorbenzene Pirimiphos-methyl Prallethrin Profenofos Pyraclofos Pyrazophos Pyridaben Pyridiphenthion Pyrifenox Quinmerac Rotenone Silafluofen Sintofen Temephos Tralomethrin Tributyltin compounds Tridiphane Validamycin XMC

Since 2011

PenthiopyradPenflufenSedaxaneo-phenylphenolGroup: Paraffin oils, Mineral oils

Paraffin oil/(CAS 64741-89-5)Paraffin oil/(CAS 64741-97-5)Paraffin oil/(CAS 64742-46-7)Paraffin oil/(CAS 64742-54-7)Paraffin oil/(CAS 64742-55-8)Paraffin oil/(CAS 64742-65-0)Paraffin oil/(CAS 72623-86-0)Paraffin oil/(CAS 97862-82-3)

IsopyrazamAmisulbromSpinetoramPyridalylPenflufenIsopyrazamIpconazolePenthiopyradSedaxane

FluxapyroxadMetazachlorFuberidazoleOxadiargylZinc phosphideCyflufenamid

Pesticides deleted from the PAN International List of Highly Hazardous Pesticides since January 2009

2009-2011

2,4-dichlorophenolBacillus subtilis GBO3Chlordimeform hydrochlorideChlorsulfuron Sulfosulfuron

Since 2011

1,2,4-triazole2,4,6-trichlorophenol2,6-DichlorbenzamidAnilineAzobenzeneBis (chloroethyl) etherChlorbensideCoconut diethanolamideDichloro acetic acidDimethoxaneDoxorubicinHeptachlor epoxideHydrazineIsophoroneMepronilMethylene chlorideP-chloroanilinePentachlorbenzenePicloram, diethanolamine saltpiperonyl butoxidTrichlorophenolTridiphane

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010

134-

31-6

8-hy

drox

yqui

nolin

e1

0

01

1

0

1171

751-

41-2

Aba

mec

tin1

0

01

1

0

1230

560-

19-1

Ace

phat

e2

0

11

11

1

0

1334

256-

82-1

Ace

toch

lor

10

1

11

0

014

6247

6-59

-9A

ciflu

orfe

n, s

odiu

m s

alt

10

1

10

0

1510

1007

-06-

1A

crin

athr

in1

0

01

1

1

0

1610

7-02

-8A

crol

ein

21

1

1

1

10

0

1715

972-

60-8

Ala

chlo

r1

0

11

11

0

018

8313

0-01

-2A

lany

carb

10

0

1

1

019

116-

06-3

Ald

icar

b3

1

1

1

11

1

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

1

5

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

2030

9-00

-2A

ldrin

30

1

11

11

1

1

11

2158

4-79

-2A

lleth

rin; B

ioal

leth

rin1

0

11

10

0

2231

9-84

-6al

pha-

BH

C;

alph

a-H

CH

20

1

10

1

1

2396

-24-

2Al

pha-

chlo

rohy

drin

11

1

0

0

024

2085

9-73

-8A

lum

inum

pho

sphi

de1

0

01

1

0

2512

0923

-37-

7Am

idos

ulfu

ron

10

0

1

1

026

1501

14-7

1-9

Amin

opyr

alid

10

0

1

1

1

027

3486

35-8

7-0

Amis

ulbr

om1

0

11

0

028

3308

9-61

-1Am

itraz

10

1

10

0

2961

-82-

5Am

itrol

e2

0

11

11

1

1

0

3090

640-

80-5

Ant

hrac

ene

oil

10

1

10

0

3177

78-3

9-4

Ars

enic

and

ist

com

poun

ds1

0

11

10

0

3233

37-7

1-1

Asu

lam

10

1

10

0

3323

02-1

7-2

Asu

lam

, so

dium

sal

t1

0

01

1

0

3419

12-2

4-9

Atra

zine

10

1

10

0

3568

049-

83-2

Aza

feni

din

10

1

10

0

3635

575-

96-3

Aza

met

hiph

os1

0

01

1

0

3726

42-7

1-9

Azi

npho

s-et

hyl

21

1

0

1

1

038

86-5

0-0

Azi

npho

s-m

ethy

l2

1

1

1

01

1

0

3941

083-

11-8

Azo

cycl

otin

21

1

0

1

1

040

1318

60-3

3-8

Azo

xyst

robi

n1

0

01

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

1

6

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

4122

781-

23-3

Ben

dioc

arb

10

0

1

1

042

1861

-40-

1B

enflu

ralin

10

1

10

0

4382

560-

54-1

Ben

fura

carb

10

0

1

1

044

1780

4-35

-2B

enom

yl2

0

11

11

0

1X

145

741-

58-2

Ben

sulid

e1

0

01

1

0

4625

057-

89-0

Ben

tazo

ne1

0

01

1

1

0

4717

7406

-68-

7B

enth

iava

licar

b-is

opro

pyl

10

1

10

0

4868

359-

37-5

Bet

a-cy

fluth

rin; C

yflu

thrin

21

1

1

0

1

1

049

319-

85-7

beta

-HC

H; b

eta-

BC

H2

0

11

0

11

5082

657-

04-3

Bife

nthr

in2

0

11

11

1

1

1

0

5148

5-31

-4Bi

napa

cryl

20

1

10

1

152

2843

4-01

-7B

iore

smet

hrin

10

0

1

1

053

2079

-00-

7B

last

icid

in-S

11

1

0

0

054

1303

-96-

4B

orax

; dis

odiu

m

tetra

bora

te d

ecah

ydra

te1

0

11

0

0

5510

043-

35-3

Bor

ic a

cid

10

1

11

0

056

1884

25-8

5-6

Bos

calid

10

1

10

0

5756

073-

10-0

Bro

difa

coum

11

1

0

0

058

314-

40-9

Bro

mac

il1

0

11

0

059

2877

2-56

-7B

rom

adio

lone

11

1

0

0

060

6333

3-35

-7B

rom

etha

lin2

1

1

01

1

0

6116

89-8

4-5

Bro

mox

ynil

21

1

1

11

0

062

1162

55-4

8-2

Bro

muc

onaz

ole

10

0

1

1

063

6932

7-76

-0B

upro

fezi

n1

0

11

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

1

7

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

6423

184-

66-9

But

achl

or1

0

11

0

065

3468

1-10

-2B

utoc

arbo

xim

10

0

1

1

066

3468

1-23

-7B

utox

ycar

boxi

m1

1

1

00

0

6795

465-

99-9

Cad

usaf

os2

1

1

01

1

1

0

6824

25-0

6-1

Cap

tafo

l3

1

1

11

11

0

11

6913

3-06

-2C

apta

n1

0

11

10

0

7063

-25-

2C

arba

ryl

20

1

11

11

1

0

7110

605-

21-7

Car

bend

azim

10

1

11

11

0

072

1563

-66-

2C

arbo

fura

n4

1

1

1

11

1

1

1X

173

5528

5-14

-8C

arbo

sulfa

n2

1

1

01

1

0

7424

39-0

1-2

Chi

nom

ethi

onat

; O

xyth

ioqu

inox

10

1

10

0

7557

-74-

9C

hlor

dane

30

1

11

11

1

1

11

7614

3-50

-0C

hlor

deco

ne3

0

11

11

1

1

1

1

11

7761

64-9

8-3

Chl

ordi

mef

orm

20

1

11

10

1

178

5459

3-83

-8C

hlor

etho

xyph

os2

1

1

01

1

0

7912

2453

-73-

0C

hlor

fena

pyr

20

1

11

1

0

8047

0-90

-6C

hlor

fenv

inph

os3

1

1

11

1

1

081

2493

4-91

-6C

hlor

mep

hos

11

1

0

0

082

510-

15-6

Chl

orob

enzi

late

10

0

0

11

8367

-66-

3C

hlor

ofor

m1

0

11

11

0

084

3691

-35-

8C

hlor

opha

cino

ne1

1

1

00

0

8576

-06-

2C

hlor

opic

rin1

1

1

00

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

1

8

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

8618

97-4

5-6

Chl

orot

halo

nil

21

1

1

11

10

0

8715

545-

48-9

Chl

orot

olur

on2

0

11

11

1

0

8810

1-21

-3C

hlor

phro

pham

10

1

10

0

8929

21-8

8-2

Chl

orpy

rifos

10

0

1

1

090

5598

-13-

0C

hlor

pyrif

os-m

ethy

l1

0

01

1

0

9118

61-3

2-1

Chl

orth

al-d

imet

hyl

10

1

10

0

9284

332-

86-5

Chl

ozol

inat

e1

0

11

0

093

67-9

7-0

Cho

leca

lcife

rol;

Vita

min

D

31

0

01

1

0

9414

2891

-20-

1C

inid

on-e

thyl

10

1

10

0

9510

5512

-06-

9C

lodi

nafo

p-pr

opar

gyl

10

1

10

0

9682

697-

71-0

Clo

fenc

et1

0

11

0

097

7411

5-24

-5C

lofe

ntez

ine

10

1

10

0

9817

02-1

7-6

Clo

pyra

lid1

0

01

1

0

9921

0880

-92-

5C

loth

iani

din

10

0

1

1

010

056

-72-

4C

oum

apho

s1

1

1

00

0

101

5836

-29-

3C

oum

atet

raly

l1

1

1

00

0

102

8001

-58-

9C

reos

ote

10

1

11

10

0

103

9948

5-76

-4C

umyl

uron

10

1

10

0

104

420-

04-2

Cya

nam

ide

10

1

10

0

105

2172

5-46

-2C

yana

zine

10

1

11

0

010

618

0409

-60-

3C

yflu

fena

mid

10

1

10

0

107

6835

9-37

-5C

yflu

thrin

21

1

0

1

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

1

9

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

108

6808

5-85

-8C

yhal

othr

in1

0

01

1

0

109

7670

3-62

-3C

yhal

othr

in, g

amm

a1

0

01

1

0

110

1312

1-70

-5C

yhex

atin

10

0

1

1

011

165

731-

84-2

Cyp

erm

ethr

in1

0

01

1

0

112

6737

5-30

-8C

yper

met

hrin

, alp

ha1

0

01

1

0

113

9436

1-06

-5C

ypro

cona

zole

20

1

11

1

1

0

114

6621

5-27

-8C

yrom

azin

e1

0

01

1

0

115

1596

-84-

5D

amin

ozid

e1

0

11

0

011

650

-29-

3D

DT

20

1

11

11

0

11

111

752

918-

63-5

Del

tam

ethr

in2

0

11

1

1

011

891

9-86

-8D

emet

on-S

-met

hyl

21

1

0

1

1

011

980

060-

09-9

Dia

fent

hiur

on1

0

01

1

0

120

333-

41-5

Dia

zino

n2

0

11

1

1

012

111

94-6

5-6

Dic

hlob

enil

10

1

10

0

122

97-2

3-4

Dic

hlor

ophe

ne1

0

11

0

012

315

165-

67-0

Dic

hlor

prop

-P1

0

11

0

012

462

-73-

7D

ichl

orvo

s; D

DV

P3

1

1

1

11

11

1

0

125

5133

8-27

-3D

iclo

fop-

met

hyl

10

1

10

0

126

115-

32-2

Dic

ofol

20

1

11

1

1

012

714

1-66

-2D

icro

toph

os3

1

1

11

1

1

012

860

-57-

1D

ield

rin3

0

11

11

1

1

1

11

112

956

073-

07-5

Dife

naco

um2

1

1

01

1

0

130

1194

46-6

8-3

Dife

noco

nazo

le2

0

11

1

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

0

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

131

1046

53-3

4-1

Dife

thia

lone

21

1

0

1

1

013

234

205-

21-5

Dim

efur

on1

0

01

1

0

133

8767

4-68

-8D

imet

hena

mid

10

1

10

0

134

5529

0-64

-7D

imet

hipi

n2

0

11

1

1

013

560

-51-

5D

imet

hoat

e2

0

11

11

1

0

136

1499

61-5

2-4

Dim

oxys

trobi

n1

0

11

10

0

137

3930

0-45

-3D

inoc

ap1

0

11

0

013

888

-85-

7D

inos

eb2

0

11

10

1

113

916

5252

-70-

0D

inot

efur

an1

0

01

1

0

140

1420

-07-

1D

inot

erb

21

1

1

10

0

141

82-6

6-6

Dip

haci

none

11

1

0

0

014

285

-00-

7D

iqua

t dib

rom

ide

11

1

0

0

014

340

32-2

6-2

Diq

uat d

ichl

orid

e1

1

1

00

0

144

298-

04-4

Dis

ulfo

ton

11

1

0

0

014

533

47-2

2-6

Dith

iano

n1

0

11

0

014

633

0-54

-1D

iuro

n1

0

11

11

0

014

753

4-52

-1D

NO

C2

1

1

1

00

1

114

817

109-

49-8

Edi

fenp

hos

11

1

0

0

014

911

5-29

-7E

ndos

ulfa

n2

1

1

11

0

015

072

-20-

8E

ndrin

20

1

10

1

115

129

7-99

-4E

-Pho

spha

mid

on1

1

1

00

0

152

106-

89-8

Epic

hlor

ohyd

rin1

0

11

11

10

0

153

2104

-64-

5E

PN

11

1

0

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

1

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

154

1338

55-9

8-8

Epo

xico

nazo

le2

0

11

11

1

1

015

575

9-94

-4E

PTC

10

0

1

1

015

628

434-

00-6

Esb

ioth

rin; S

-Bio

alle

thrin

10

1

10

0

157

6623

0-04

-4E

sfen

vale

rate

10

0

1

1

015

816

2650

-77-

3E

thab

oxam

10

1

10

0

159

5528

3-68

-6E

thal

flura

lin1

0

11

0

016

029

973-

13-5

Eth

iofe

ncar

b1

1

1

00

0

161

6452

9-56

-2E

thio

zin

10

1

10

0

162

1815

87-0

1-9

Eth

ipro

le1

0

11

0

016

323

947-

60-6

Eth

irim

ol1

0

01

1

0

164

2622

5-79

-6E

thof

umes

ate

10

0

1

1

016

513

194-

48-4

Eth

opro

phos

; Eth

opro

p2

1

1

1

11

0

016

610

6-93

-4E

thyl

ene

dibr

omid

e; 1

,2-

dibr

omoe

than

e2

0

11

11

10

1

1

167

107-

06-2

Eth

ylen

e di

chlo

ride

20

1

11

0

11

168

75-2

1-8

Eth

ylen

e ox

ide

20

1

11

10

1

116

996

-45-

7E

thyl

ene

thio

urea

10

1

11

10

0

170

8084

4-07

-1E

tofe

npro

x; E

thof

enpr

ox2

0

11

1

1

017

152

-85-

7Fa

mph

ur1

1

1

00

0

172

2222

4-92

-6Fe

nam

ipho

s2

1

1

01

1

0

173

6016

8-88

-9Fe

narim

ol1

0

11

0

017

412

0928

-09-

8Fe

naza

quin

10

0

1

1

017

511

4369

-43-

6Fe

nbuc

onaz

ole

10

1

10

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

2

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

176

1335

6-08

-6Fe

nbut

atin

-oxi

de1

1

1

00

0

177

1031

12-3

5-2

Fenc

hlor

azol

e-et

hyl

00

0

0

017

812

2-14

-5Fe

nitro

thio

n2

0

11

1

1

017

962

850-

32-2

Feno

thio

carb

10

0

1

1

018

072

490-

01-8

Feno

xyca

rb2

0

11

11

1

0

181

3951

5-41

-8Fe

npro

path

rin2

1

1

01

1

0

182

6730

6-00

-7Fe

npro

pidi

n1

0

11

0

018

355

-38-

9Fe

nthi

on1

0

01

1

0

184

900-

95-8

Fent

in a

ceta

te;

Trip

heny

ltin

acet

ate

21

1

1

11

0

0

185

76-8

7-9

Fent

in h

ydro

xide

; Tr

iphe

nylti

n hy

drox

ide

21

1

1

11

10

0

186

5163

0-58

-1Fe

nval

erat

e2

0

11

1

1

018

712

0068

-37-

3Fi

pron

il2

0

11

1

1

018

890

035-

08-8

Floc

oum

afen

11

1

1

0

0

018

915

8062

-67-

0Fl

onic

amid

10

1

10

0

190

6980

6-50

-4Fl

uazi

fop-

buty

l1

0

11

0

019

179

622-

59-6

Flua

zina

m1

0

11

0

019

270

124-

77-5

Fluc

ythr

inat

e2

1

1

01

1

1

0

193

1313

41-8

6-1

Flud

ioxo

nil

10

0

1

1

019

410

1463

-69-

8Fl

ufen

oxur

on1

0

01

1

0

195

1033

61-0

9-7

Flum

ioxa

zin

10

1

10

0

196

2164

-17-

2Fl

uom

etur

on2

0

11

1

1

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

3

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

197

2391

10-1

5-7

Fluo

pico

lide

10

0

1

1

1

019

865

8066

-35-

4Fl

uopy

ram

20

1

11

1

0

199

640-

19-7

Fluo

roac

etam

ide

21

1

0

0

11

200

8550

9-19

-9Fl

usila

zole

20

1

11

1

1

020

111

7337

-19-

6Fl

uthi

acet

-met

hyl

10

1

10

0

202

6633

2-96

-5Fl

utol

anil

10

0

1

1

1

020

390

7204

-31-

3Fl

uxap

yrox

ad1

0

01

1

0

204

133-

07-3

Folp

et1

0

11

10

0

205

6815

7-60

-8Fo

rchl

orfe

nuro

n1

0

11

0

020

650

-00-

0Fo

rmal

dehy

de1

0

11

11

0

020

722

259-

30-9

Form

etan

ate

21

1

1

0

1

1

020

898

886-

44-3

Fost

hiaz

ate

10

0

1

1

020

938

78-1

9-1

Fube

ridaz

ole

10

1

10

0

210

6590

7-30

-4Fu

rath

ioca

rb1

1

1

1

00

0

211

98-0

1-1

Furfu

ral

10

1

10

0

212

1217

76-3

3-8

Furil

azol

e1

0

11

0

021

377

182-

82-2

Glu

fosi

nate

-am

mon

ium

10

1

10

0

214

8159

1-81

-3G

lyph

osat

e tri

mes

ium

10

0

1

1

021

569

806-

40-2

Hal

oxyf

op-m

ethy

l (u

nsta

ted

ster

eoch

emis

try)

10

1

10

0

216

76-4

4-8

Hep

tach

lor

30

1

11

11

1

1

11

121

723

560-

59-0

Hep

teno

phos

11

1

0

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

4

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

218

118-

74-1

Hex

achl

orob

enze

ne4

1

1

11

11

11

1

1

11

219

67-7

2-1

Hex

achl

oroe

than

e1

0

11

10

0

220

7998

3-71

-4H

exac

onaz

ole

20

1

11

1

0

221

8647

9-06

-3H

exaf

lum

uron

10

0

1

1

022

260

8-73

-1H

exch

loro

cycl

ohex

ane

20

1

11

10

1

122

378

587-

05-0

Hex

ythi

azox

10

1

10

0

224

6748

5-29

-4H

ydra

met

hyln

on2

0

11

1

1

022

535

554-

44-0

Imaz

alil

10

1

10

0

226

8133

5-37

-7Im

azaq

uin

10

0

1

1

1

022

781

335-

77-5

Imaz

etha

pyr

10

0

1

1

022

813

8261

-41-

3Im

idac

lopr

id1

0

01

1

0

229

1735

84-4

4-6

Indo

xaca

rb1

0

01

1

0

230

74-8

8-4

Iodo

met

hane

10

1

11

0

023

116

89-8

3-4

Ioxy

nil

10

1

10

0

232

1252

25-2

8-7

Ipco

nazo

le1

0

01

1

0

233

3673

4-19

-7Ip

rodi

one

10

1

11

10

0

234

1409

23-1

7-7

Ipro

valic

arb

20

1

11

1

0

235

3412

3-59

-6Is

opro

turo

n1

0

11

0

023

688

1685

-58-

1Is

opyr

azam

20

1

11

1

0

237

8255

8-50

-7Is

oxab

en1

0

11

0

023

814

1112

-29-

0Is

oxaf

luto

le1

0

11

0

023

918

854-

01-8

Isox

athi

on2

1

1

01

1

0

240

6527

7-42

-1K

etoc

onaz

ole

10

1

11

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

5

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

241

1433

90-8

9-0

Kre

soxi

m-m

ethy

l1

0

11

10

0

242

7750

1-63

-4La

ctof

en1

0

11

0

024

391

465-

08-6

Lam

bda-

cyha

loth

rin3

1

1

11

1

1

024

421

64-0

8-1

Lena

cil

10

0

1

1

024

558

-89-

9Li

ndan

e3

0

11

11

1

1

11

124

633

0-55

-2Li

nuro

n1

0

11

11

10

0

247

1030

55-0

7-8

Lufe

nuro

n1

0

01

1

1

0

248

121-

75-5

Mal

athi

on2

0

11

11

1

0

249

8018

-01-

7M

anco

zeb

10

1

11

0

025

012

427-

38-2

Man

eb1

0

11

10

0

251

94-7

4-6

MC

PA

10

1

10

0

252

94-8

1-5

MC

PB

10

1

10

0

253

7085

-19-

0M

CP

P1

0

11

0

025

425

95-5

4-2

Mec

arba

m1

1

1

00

0

255

1648

4-77

-8M

ecop

rop-

P1

0

11

10

0

256

1102

35-4

7-7

Mep

anip

yrim

10

1

11

0

025

774

39-9

7-6

Mer

cury

and

its

com

poun

ds2

1

1

00

1

1

258

108-

39-4

Met

a-cr

esol

10

1

10

0

259

108-

62-3

Met

alde

hyde

10

1

10

0

260

137-

41-7

Met

am-p

otas

sium

10

1

10

0

261

137-

42-8

Met

am-s

odiu

m1

0

11

10

0

262

6712

9-08

-2M

etaz

achl

or1

0

01

1

0

263

1251

16-2

3-6

Met

cona

zole

10

0

1

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

6

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

264

1869

1-97

-9M

etha

benz

thia

zuro

n1

0

01

1

1

1

0

265

1026

5-92

-6M

etha

mid

opho

s3

1

1

1

01

1

1

X1

266

950-

37-8

Met

hida

thio

n3

1

1

11

1

1

026

720

32-6

5-7

Met

hioc

arb

21

1

0

1

1

026

816

752-

77-5

Met

hom

yl3

1

1

11

1

1

026

972

-43-

5M

etho

xych

lor

10

1

10

0

270

74-8

3-9

Met

hyl b

rom

ide

20

1

10

1

127

155

6-61

-6M

ethy

l iso

thio

cyan

ate

10

1

10

0

272

9006

-42-

2M

etira

m1

0

11

10

0

273

3060

-89-

7M

etob

rom

uron

10

0

1

1

027

451

218-

45-2

Met

olac

hlor

20

1

11

1

1

0

275

1993

7-59

-8M

etox

uron

10

0

1

1

027

622

0899

-03-

6M

etra

feno

ne1

0

11

0

027

721

087-

64-9

Met

ribuz

in1

0

11

0

027

844

3-48

-1M

etro

nida

zole

10

1

10

0

279

7422

3-64

-6M

etsu

lfuro

n-m

ethy

l1

0

01

1

0

280

7786

-34-

7M

evin

phos

31

1

1

11

1

0

281

136-

45-8

MG

K 32

61

0

11

0

028

2no

cas

1562

Milb

emec

tin1

0

01

1

0

283

2385

-85-

5M

irex

30

1

11

11

1

1

128

422

12-6

7-1

Mol

inat

e1

0

11

11

0

028

571

526-

07-3

MO

N 4

660

10

1

10

0

286

6923

-22-

4M

onoc

roto

phos

31

1

1

0

1

1

1X

1

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

7

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

287

8867

1-89

-0M

yclo

buta

nil

10

0

1

1

028

830

0-76

-5N

aled

10

0

1

1

028

915

299-

99-7

Nap

ropa

mid

e1

0

01

1

0

290

1119

91-0

9-4

Nic

osul

furo

n1

0

01

1

0

291

54-1

1-5

Nic

otin

e1

1

1

00

0

292

1508

24-4

7-8

Nite

npyr

am1

0

01

1

0

293

1929

-82-

4N

itrap

yrin

10

1

10

0

294

98-9

5-3

Nitr

oben

zene

10

1

11

10

0

295

90-4

3-7

o-ph

enyl

phen

ol1

0

11

0

029

627

314-

13-2

Nor

flura

zon

10

1

10

0

297

1113

-02-

6O

met

hoat

e3

1

1

11

1

1

029

821

3464

-77-

8O

rthos

ulfa

mur

on1

0

11

0

029

919

044-

88-3

Ory

zalin

10

1

10

0

300

3980

7-15

-3O

xadi

argy

l1

0

11

0

030

119

666-

30-9

Oxa

diaz

on1

0

11

0

030

277

732-

09-3

Oxa

dixy

l1

0

11

0

030

323

135-

22-0

Oxa

myl

21

1

1

0

1

1

030

452

59-8

8-1

Oxy

carb

oxin

10

0

1

1

1

030

530

1-12

-2O

xyde

met

on-m

ethy

l2

1

1

01

1

0

306

4287

4-03

-3O

xyflu

orfe

n1

0

11

0

030

776

738-

62-0

Pac

lobu

trazo

l1

0

01

1

1

0

308

106-

46-7

Par

a-di

chlo

robe

nzen

e1

0

11

10

0

309

6474

1-88

-4P

araf

fin o

ils; m

iner

al o

ils1

0

11

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

8

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

310

1910

-42-

5P

araq

uat d

ichl

orid

e1

1

1

00

0

311

56-3

8-2

Par

athi

on3

1

1

11

11

1

0

312

298-

00-0

Par

athi

on-m

ethy

l3

1

1

1

11

0

11

313

87-8

6-5

PC

P3

1

1

1

11

11

10

1

131

466

246-

88-6

Pen

cona

zole

10

0

1

1

031

540

487-

42-1

Pen

dim

etha

lin2

0

11

1

1

031

649

4793

-67-

8P

enflu

fen

20

1

11

1

0

317

2197

14-9

6-2

Pen

oxsu

lam

10

1

10

0

318

1836

75-8

2-3

Pen

thio

pyra

d2

0

11

1

1

031

952

645-

53-1

Per

met

hrin

20

1

11

1

1

032

026

002-

80-2

Phe

noth

rin1

0

11

0

032

125

97-0

3-7

Phe

ntho

ate

20

1

11

1

0

322

298-

02-2

Pho

rate

21

1

0

1

1

032

373

2-11

-6P

hosm

et2

0

11

1

1

032

413

171-

21-6

Pho

spha

mid

on4

1

1

11

11

1

1

132

578

03-5

1-2

Pho

sphi

ne1

1

1

00

0

326

1918

-02-

1P

iclo

ram

20

1

11

1

1

0

327

2310

3-98

-2P

irim

icar

b2

0

11

1

1

032

829

232-

93-7

Piri

mip

hos-

met

hyl

10

0

1

1

032

932

289-

58-0

Pol

yhex

amet

hyle

ne

bigu

anid

ine

10

1

10

0

330

299-

45-6

Pot

asan

11

1

0

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

2

9

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

331

2303

1-36

-9P

ralle

thrin

10

0

1

1

033

267

747-

09-5

Pro

chlo

raz

20

1

11

1

1

1

033

332

809-

16-8

Pro

cym

idon

e1

0

11

10

0

334

2909

1-21

-2P

rodi

amin

e1

0

11

0

033

541

198-

08-7

Pro

feno

fos

10

0

1

1

033

613

9001

-49-

3P

rofo

xydi

m1

0

11

10

0

337

7287

-19-

6P

rom

etry

n1

0

11

0

033

819

18-1

6-7

Pro

pach

lor

10

1

10

0

339

709-

98-8

Pro

pani

l1

0

11

10

0

340

2312

-35-

8P

ropa

rgite

20

1

11

1

1

034

113

9-40

-2P

ropa

zine

20

1

11

1

0

342

3121

8-83

-4P

rope

tam

phos

11

1

0

0

034

360

207-

90-1

Pro

pico

nazo

le2

0

11

1

1

034

411

4-26

-1P

ropo

xur

20

1

11

1

0

345

75-5

6-9

Pro

pyle

ne o

xide

10

1

11

0

034

623

950-

58-5

Pro

pyza

mid

e1

0

11

10

0

347

5288

8-80

-9P

rosu

lfoca

rb1

0

01

1

0

348

1233

12-8

9-0

Pym

etro

zine

10

1

11

0

034

977

458-

01-6

Pyr

aclo

fos

10

0

1

1

035

012

9630

-19-

9P

yraf

lufe

n-et

hyl

10

1

10

0

351

3654

00-1

1-9

Pyr

asul

foto

le2

0

11

1

1

1

035

213

457-

18-6

Pyr

azop

hos

10

0

1

1

035

310

8-34

-9P

yraz

oxon

11

1

0

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

3

0

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

354

121-

21-1

Pyr

ethr

ins

10

1

11

0

035

596

489-

71-3

Pyr

idab

en1

0

01

1

0

356

1791

01-8

1-6

Pyr

idal

yl1

0

01

1

0

357

119-

12-0

Pyr

idip

hent

hion

10

0

1

1

035

888

283-

41-4

Pyr

ifeno

x1

0

01

1

0

359

5311

2-28

-0P

yrim

etha

nil

10

1

10

0

360

1233

43-1

6-8

Pyr

ithio

bac-

sodi

um1

0

11

0

036

144

7399

-55-

5P

yrox

asul

fone

10

1

10

0

362

1359

3-03

-8Q

uina

lpho

s2

0

11

1

1

036

390

717-

03-6

Qui

nmer

ac1

0

01

1

0

364

2797

-51-

5Q

uino

clam

ine

10

0

1

1

036

512

4495

-18-

7Q

uino

xyfe

n1

0

01

1

0

366

82-6

8-8

Qui

ntoz

ene

10

1

10

0

367

1197

38-0

6-6

Qui

zalo

fop-

p-te

fury

l1

0

11

0

036

810

453-

86-8

Res

met

hrin

20

1

11

1

1

036

983

-79-

4R

oten

one

10

0

1

1

037

087

4967

-67-

6S

edax

ane

20

1

11

1

0

371

1050

24-6

6-6

Sila

fluof

en1

0

11

0

037

217

5217

-20-

6S

ilthi

ofam

10

0

1

1

037

312

2-34

-9S

imaz

ine

10

1

11

0

037

413

0561

-48-

7S

into

fen

10

0

1

1

037

587

392-

12-9

S-M

etol

achl

or1

0

11

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

3

1

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

376

128-

04-1

Sod

ium

dim

ethy

l dith

io

carb

amat

e1

0

11

0

0

377

62-7

4-8

Sod

ium

fluo

roac

etat

e (1

080)

11

1

1

0

0

0

378

1871

66-1

5-0

Spi

neto

ram

10

0

1

1

1

037

916

8316

-95-

8S

pino

sad

10

0

1

1

038

014

8477

-71-

8S

piro

dicl

ofen

10

1

10

0

381

57-2

4-9

Stry

chni

ne1

1

1

00

0

382

3689

-24-

5S

ulfo

tep

11

1

0

0

038

321

564-

17-0

TCM

TB2

1

1

11

0

038

410

7534

-96-

3Te

buco

nazo

le2

0

11

1

1

038

511

9168

-77-

3Te

bufe

npyr

ad1

0

11

0

038

696

182-

53-5

Tebu

pirim

ifos

11

1

0

0

038

779

538-

32-2

Teflu

thrin

21

1

0

1

1

038

833

5104

-84-

2Te

mbo

trion

e1

0

11

0

038

933

83-9

6-8

Tem

epho

s1

0

01

1

0

390

1499

79-4

1-9

Tepr

alox

ydim

10

1

11

0

039

113

071-

79-9

Terb

ufos

11

1

0

0

039

288

6-50

-0Te

rbut

ryn

10

1

11

0

039

325

93-1

5-9

Terra

zole

; Etri

diaz

ole

10

1

11

10

0

394

2224

8-79

-9Te

trach

lorv

inph

os2

0

11

1

1

039

511

2281

-77-

3Te

traco

nazo

le2

0

11

1

1

039

676

96-1

2-0

Tetra

met

hrin

20

1

11

1

0

397

148-

79-8

Thia

bend

azol

e1

0

11

0

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

3

2

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

398

1119

88-4

9-9

Thia

clop

rid1

0

11

0

039

915

3719

-23-

4Th

iam

etho

xam

10

0

1

1

040

011

7718

-60-

2Th

iazo

pyr

10

1

10

0

401

5966

9-26

-0Th

iodi

carb

20

1

11

1

0

402

3919

6-18

-4Th

iofa

nox

21

1

0

1

1

040

364

0-15

-3Th

iom

eton

21

1

0

1

1

040

423

564-

05-8

Thio

phan

ate-

met

hyl

10

1

10

0

405

62-5

6-6

Thio

urea

10

1

11

0

040

613

7-26

-8Th

iram

20

1

10

1

X1

407

731-

27-1

Toly

lflua

nid

21

1

1

10

0

408

2106

31-6

8-8

Topr

amez

one

20

1

11

1

0

409

8001

-35-

2To

xaph

ene

30

1

11

11

1

1

11

141

087

820-

88-0

Tral

koxy

dim

20

1

11

1

0

411

6684

1-25

-6Tr

alom

ethr

in1

0

01

1

0

412

4312

1-43

-3Tr

iadi

mef

on1

0

11

10

0

413

5521

9-65

-3Tr

iadi

men

ol1

0

11

10

0

414

2303

-17-

5Tr

i-alla

te2

0

11

1

1

041

582

097-

50-5

Tria

sulfu

ron

10

0

1

1

1

041

624

017-

47-8

Tria

zoph

os1

1

1

00

0

417

1012

00-4

8-0

Trib

enur

on m

ethy

l1

0

11

0

041

878

-48-

8Tr

ibuf

os1

0

11

0

041

9no

cas

8Tr

ibut

yltin

com

poun

ds1

0

11

0

042

052

-68-

6Tr

ichl

orfo

n2

0

11

11

1

0

PA

N In

tern

atio

nal l

ist o

f Hig

hly

Haz

ardo

us P

estic

ides

- P

AN

Ger

man

y fo

r PA

N In

tern

atio

nal -

05/

2013

3

3

PAN

Inte

rnat

iona

l Lis

t of H

ighl

y H

azar

dous

Pes

ticid

es -

PAN

Ger

man

y fo

r PA

N In

tern

atio

nal -

May

2013

Gro

up 1

: A

cute

Tox

icity

Gro

up 2

: Lo

ng te

rm e

ffect

sG

roup

3:

Env

ironm

enta

l tox

icity

Gro

up 4

: C

onve

ntio

ns

CAS

num

ber

Pest

icid

e


WHO Ia

WHO Ib

H330

Max = 1

EPA carc

IARC carc


EPA prob likel carc

IARC prob carc

EPA poss carc

IARC poss carc

EU GHS carc (2)




Max = 1

Very bio acc

Very pers water


Highly toxic bees

Max = 1

Montreal Protokoll




Max = 1

421

3380

-34-

5Tr

iclo

san

10

1

10

0

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Explanatory notes WHO 1a: Extremely hazardous (Class 1a) according to World Health Organisation WHO 1b: Highly hazardous (Class 1b) according to World Health Organisation H330 Fatal if inhaled according to the Globally Harmonised System (GHS) max = 1 This active ingredient meets at least one criteria in this Group EPA carc Human carcinogen according to EPA IARC carc Human carcinogen according to IARC EU GHS (1A, 1B): Known or presumed human carcinogens (1A or 1B) according to EU GHS Regulation

1272/2008/EC EPA prob/likel carc Probable/ Likely carcinogen according to EPA IARC prob carc Probable carcinogen according to IARC EPA poss carc: Possible carcinogen according to EPA IARC poss carc: Possible carcinogen according to IARC EU GHS (2): Suspected human carcinogen (Cat. 2) according to EU GHS Regulation 1272/2008/EC EU GHS muta (1A, 1B) Substances known to induce heritable mutations or to be regarded as if they induce

heritable mutations in the germ cells of humans. Substances known to induce heritable mutations in the germ cells of humans’ (Category 1A or 1B) according to EU Regulation 1272/2008/EC

EU GHS repro (1A, 1B): Substances known to impair fertility in humans (category 1) or substances which should be regarded as if they impair fertility in humans and/or substances which should be regarded as if they cause developmental toxicity to humans (category 2) according to EU

EU EDC (1,2) or C2 & R2 GHS: Endocrine disruptor or potential endocrine disruptor according to EU Category 1 or Category 2 or GHS Carcer 2 AND EU reproductive toxicity

Very bio acc: Very bioaccumulative according to REACh criteria Very pers water: Very persistent/water according to REACh criteria Very pers water sedi: Very persistent in water/sediment according to REACh criteria Highly toxic bees: Hazard to ecosystem services – Highly toxic for bees according to U.S. EPA as listed

by FOOTPRINT data Montr Prot: Ozone depleting according to the Montreal Protocol PIC: Listed in Annex III of the Rotterdamer Convention POP: Listed in Annex III of the Stockholmer Convention

pan international list of highly hazardous pesticides (pan...

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