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Page 1: Osteoporosis

OsteoporosisOsteoporosisSlide showSlide show

Page 2: Osteoporosis

The Osteoporosis LandscapeThe Osteoporosis Landscape

In India, an estimated 43 million women suffer from osteoporosis

Page 3: Osteoporosis

India: Some Hard Facts India: Some Hard Facts Over 61 Million Indians have

osteoporosis.

80% are women.

On a global basis, Indians have the highest prevalence of osteopenia.

Compared to Caucasians, osteoporotic fractures in the Indian population occur 10-12 years earlier in age.

Osteoporotic fractures are more common in Indian men than in the West.

Page 4: Osteoporosis

India: Some more hard factsIndia: Some more hard facts

Over 45 Lakhs Indian women above 60 have a fractured spine.

Over 2.5 Lakhs Indians suffer osteoporotic hip fractures every year.

Most of these fractures are never investigated for osteoporosis - and therefore never treated for the cause.

Gupta et al, Indian Journal of Medical Research 1967:55:1341-8

Page 5: Osteoporosis

Incidence of Hip fracturesIncidence of Hip fractures

Asia will emerge as the largest sufferer of osteoporosis related

fractures

Page 6: Osteoporosis

Osteoporosis vs other Osteoporosis vs other diseasesdiseases

Total incidence of osteoporosis related fractures far exceeds other

diseases

Page 7: Osteoporosis

What makes us more prone?What makes us more prone? Indians have a poor calcium intake

– We don’t drink enough milk as children– We have a higher incidence of varied degrees of lactose intolerance– Rice is a poor source of calcium– Vegetarian diets and cereals have low bio-availability of calcium

(<30%)

Vit D deficiency is common

Protein intake is poor

Excess salt intake – may increase urinary loss of calcium

Healthy exercise is neglected

Significantly lower BMD: mean spinal BMD by DEXA is 2SD below the American-European population between 20 to 59 yrs population*

Lower BMI: osteoporosis is more common in thin women

Late menarche’ in girls - low estrogen exposure

Awareness is low*Nangia et al, ESICON 1977

Page 8: Osteoporosis

Why is osteoporosis serious?Why is osteoporosis serious?

It affects many more women than heart attacks, strokes and breast cancer together

Osteoporosis kills by its complications-An osteoporotic fracture reduces the sufferer’s life expectancy by a decade.

In addition, it seriously compromises quality of life

Fractures are very expensive to treat-the economic burden of osteoporotic fractures is immense.

Page 9: Osteoporosis

Common Fracture/BMD Common Fracture/BMD measurement Sitesmeasurement Sites

Page 10: Osteoporosis

World Health Organization (WHO)World Health Organization (WHO)

guidelines for osteoporosisguidelines for osteoporosis

Osteoporosis Osteopenia

Normal

Peak Bone Mass

-2.5 -2 0T-Score -1

Page 11: Osteoporosis

Who to Treat?Who to Treat?

Therapy Decision

High Risk

Treat

Moderate Risk

Treat if other risk factors

Low Risk

Check again in 1-2 years

T-Score*

Below -2.5

-1.0 to -2.5

Above -1.0

International Osteoporosis Foundation. 1998.

Page 12: Osteoporosis

Osteoporosis: a team work

Patient & Family

Dietitian

Physio.

Govt.NGO

Sp. Doctor

OrthotistFm. Doctor

Sp. NurseOrthopaedic

Surgeon