neville, thanh huynh, md, mshs (maiden name: huynh)december 2016-current faculty mentor for internal...

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1 Neville, Thanh Huynh, MD, MSHS (Maiden Name: Huynh) [email protected] UCLA Med-Pulm & Critical Care BOX 951690, 43-229 CHS Los Angeles, CA 90095-1690 310-825-8599 EDUCATION University of California, Irvine B.S. Biological Sciences, Summa Cum Laude September 1996-June 2000 David Geffen School of Medicine at UCLA Doctor of Medicine August 2000-June 2005 Categorical Residency Training in Internal Medicine UCLA Medical Center - Department of Medicine July 2005-June 2008 Fellowship in Pulmonary and Critical Care UCLA Medical Center - Department of Medicine July 2008-June 2011 UCLA School of Public Health Masters in Health Services July 2010-June 2012 Kennemer Ethics Fellow UCLA Medical Center - Department of Medicine July 2010-2012 LICENSURE CA, A98492 BOARD CERTIFICATION Internal Medicine 8/25/08 Pulmonary Disease 10/12/10 Critical Care Medicine 11/9/11 PROFESSIONAL EXPERIENCE Assistant Professor-in-Residence, Division of Pulmonary & Critical Care, David Geffen School of Medicine at UCLA, July 2016-current Health Sciences Assistant Clinical Professor, Division of Pulmonary & Critical Care, David Geffen School of Medicine at UCLA, July 2014-June 2016 Clinical Instructor, Division of Pulmonary & Critical Care, David Geffen School of Medicine at UCLA, July 2012-2014

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Page 1: Neville, Thanh Huynh, MD, MSHS (Maiden Name: Huynh)December 2016-current Faculty Mentor for Internal Medicine Residents (Neha Agarwal, Jiyeon Seo). September 2017-2019 Faculty Mentor

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Neville, Thanh Huynh, MD, MSHS

(Maiden Name: Huynh)

[email protected]

UCLA Med-Pulm & Critical Care

BOX 951690, 43-229 CHS

Los Angeles, CA 90095-1690

310-825-8599

EDUCATION

University of California, Irvine

B.S. Biological Sciences, Summa Cum Laude

September 1996-June 2000

David Geffen School of Medicine at UCLA

Doctor of Medicine

August 2000-June 2005

Categorical Residency Training in Internal Medicine

UCLA Medical Center - Department of Medicine

July 2005-June 2008

Fellowship in Pulmonary and Critical Care

UCLA Medical Center - Department of Medicine

July 2008-June 2011

UCLA School of Public Health

Masters in Health Services

July 2010-June 2012

Kennemer Ethics Fellow

UCLA Medical Center - Department of Medicine

July 2010-2012

LICENSURE

CA, A98492

BOARD CERTIFICATION

Internal Medicine 8/25/08

Pulmonary Disease 10/12/10

Critical Care Medicine 11/9/11

PROFESSIONAL EXPERIENCE

Assistant Professor-in-Residence, Division of Pulmonary & Critical Care, David Geffen School of

Medicine at UCLA, July 2016-current

Health Sciences Assistant Clinical Professor, Division of Pulmonary & Critical Care, David Geffen School

of Medicine at UCLA, July 2014-June 2016

Clinical Instructor, Division of Pulmonary & Critical Care, David Geffen School of Medicine at UCLA,

July 2012-2014

Page 2: Neville, Thanh Huynh, MD, MSHS (Maiden Name: Huynh)December 2016-current Faculty Mentor for Internal Medicine Residents (Neha Agarwal, Jiyeon Seo). September 2017-2019 Faculty Mentor

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Staff Associate Physician, Division of Pulmonary & Critical Care, David Geffen School of Medicine at

UCLA, July 2011-2012

PROFESSIONAL ACTIVITIES:

Quality Improvement Committee Member in UCLA Div. of Pulmonary Critical Care. July 2009-current

Chief Pulmonary Critical Care Fellow. July 2010-2011

Member of UCLA Ethics Committee. July 2010-current

Faculty Mentor for Internal Medicine Resident (Bryan Garber). September 2011-2015

Sepsis Mortality Case Review Committee. August 2012-2013

Member of Scholarly Oversight Committee for PICU fellow (Leanna Huard). January 2013-2015

Quality Improvement Committee Chair for UCLA Div. of Pulmonary Critical Care. June 2013-Aug 2017

Medical ICU Subcommittee Member. July 2014-current

Ebola Response Team, UCLA. October 2014-2015

Rapid Mortality Review Pulmonary Critical Care Leader. Jan 2015-current

Faculty Mentor for Pulmonary Critical Care Fellow (Bryan Garber). July 2015-current

Fellows Clinical Research Committee Chair. July 2016-current

Fellows Clinical Competency Committee Member. Nov 2016-current

Co-chair of Ethics Core for UCLA Critical Care Center. December 2016-current

Faculty Mentor for Internal Medicine Residents (Neha Agarwal, Jiyeon Seo). September 2017-2019

Faculty Mentor for Pulmonary Critical Care Fellow (Allison Ramsey). July 2017-2019

Faculty Mentor for Pulmonary Critical Care Fellow (Kristen Schwab). July 2018-current

UCLA 3 Wishes Program Director and Co-Founder. December 2017-current

PROFESSIONAL MEMBERSHIPS

American Thoracic Society 2008-current

Society of Critical Care Medicine 2008-current

American College Chest Physicians 2009-current

American Society for Bioethics and Humanities 2010-2015, 2019-current

American Academy of Hospice and Palliative Medicine 2018-current

HONORS AND SPECIAL AWARDS

Class Valedictorian (1996)

Dean’s Honor List (1996-2000)

Campuswide Honors Program (1996-2000)

Regents Scholarship, Robert C. Byrd Scholarship, Alumni Association Scholarship, Scholar’s Circle

Chancellor Scholarship (1996-2000)

Golden Key National Honor Society (1998-2000)

Phi Beta Kappa (1999)

Summa cum laude (2000)

Subspecialty Award at 30th Annual Western Student Medical Research Forum (2002)

American Academy of Neurology, Saul Korey Award in Experimental Neurology (2003)

Letter of Distinction in Inpatient Internal Medicine, Neurology, and Psychiatry Clinical Clerkships (2004)

Dr. Pramod Gan (Olive View) Student of the Year in Medicine Award (2005)

Commendation for Excellence in Medical Student Teaching (2006, 2007, 2008)

Nomination for Fellow of the Year (2009)

Third Place, UCLA Department of Medicine Research Day Poster Competition (Oct. 2012)

Fifth Place, UCLA Department of Medicine Research Day Poster Competition (Oct. 2013)

Butler-Williams Scholars Program, NIH NIA (August 2014)

Page 3: Neville, Thanh Huynh, MD, MSHS (Maiden Name: Huynh)December 2016-current Faculty Mentor for Internal Medicine Residents (Neha Agarwal, Jiyeon Seo). September 2017-2019 Faculty Mentor

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Third Place, UCLA Department of Medicine Research Day Poster Competition (Oct. 2015)

NIH Summer Institute on Behavioral Randomized Control Trials (July 2017)

Nominated for 2019 UCLA Exceptional Physician Award (April 2019)

Nominated for 2019 UCLA Cultural North Star Award (October 2019)

SCCM 2020 Family-Centered Care Award to 3 Wishes Team (February 2020)

RESEARCH GRANTS AND FELLOWSHIPS RECEIVED

American Heart Association Research Program Awardee (1998)

Purpose: to perform cardiovascular research, summer-long project.

Amount: $2000

Research Fellowship Grant from Undergraduate Research Opportunities Program (1999)

Purpose: to perform independent research project.

Amount: $3000

NIH-Howard Hughes Medical Institute Research Scholar (2002- 2003)

Purpose: to perform translational research at the NIH.

Amount: $45,000

Kennemer Fellowship Awardee (July 2010-June 2012)

Purpose: to do ICU outcomes research, participate in Ethics, obtain Masters in Health Services

Amount: $60,000

NIH Loan Repayment Program: NINR (PI: Huynh, 2011-2013)

Purpose: to have medical school loans repaid while having a research career

Amount: $56,000

NIH T32 Grant (PI: Dubinett, July 2012-July 2013)

Purpose: to do clinical research at UCLA

Amount: $51,000

UCLA CTSI KL2 UL1TR000124 (PI: Neville, July 2014-Aug 2015)

Purpose: to compare patients who received futile treatment vs those who did not

Amount: $124,000

NIH Loan Repayment Program: NIA (PI: Neville, 2015-2016)

Purpose: to have medical school loans repaid while having a research career

Amount: $28,000

NIH-NIA K23AG047900-01A1 Career Development Award (PI: Neville, August 2015-August 2020)

Purpose: Understanding Inappropriate Treatment In Critically Ill Older Patients

Amount: $714,500

ABIM Professionalism Challenge Grant (PI: Wenger, April 2016-2018)

Purpose: The Professionalism Challenge: Reducing Inappropriate Critical Care

Amount: $25,000

NIH/National Center for Advancing Translational Sciences UCLA CTSI Grant (PI: Dong, April 2017-2019)

Page 4: Neville, Thanh Huynh, MD, MSHS (Maiden Name: Huynh)December 2016-current Faculty Mentor for Internal Medicine Residents (Neha Agarwal, Jiyeon Seo). September 2017-2019 Faculty Mentor

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Purpose: Evaluate Time Limited Trials to Reduce Non‐Beneficial Intensive Care Unit

Treatments Among Critically‐Ill Patients with Advanced Medical Illnesses

Amount: $75,000

CSU Palliative Care Institute (PI: Neville, Oct 2017-Oct 2018)

Purpose: Creating a Meaningful End of Life Experience for Older Patients (Evaluate 3 Wishes

Intervention in the UCLA MICU)

Amount: $10,000

NIH Loan Repayment Program: NIA (PI: Neville, 2017-2019)

Purpose: to have medical school loans repaid while having a research career

Amount: $14,888

UCLA Auxiliary Grant (PI: Neville, Dec 2018-2019)

Purpose: to supply material gifts for patients in the 3 Wishes Projects

Amount: $10,000

UCLA Critical Care Center Research Award (PI: Neville, July 2019-2020)

Purpose: to evaluate the implementation of the 3WP in the Liver ICU

Amount: $25,000

UCLA Health Innovation Challenge (PI: Neville, July 2019-2020)

Purpose: Expansion of the 3Wishes Project to L&D and Geriatrics Units

Amount: $5,000

LECTURES AND PRESENTATIONS: 1. American Heart Association. Student research fellowship conference. “The Effect of VAD Circulation on

Complement Activation”. Irvine, CA. August 1998.

2. Cardiology Conference: “Cardiovascular Research—From the Laboratory to the Clinics”. UC Irvine

Medical Center, Irvine, CA. October 1998.

3. 27th Annual Western Student Medical Research Forum. “Complement Activation During VAD Circulation”.

Carmel, CA. January 1999.

4. Undergraduate Research Symposium. “Alternative Pathway of Complement is Activated During Ventricular

Assist”. UC Irvine. Irvine, CA. May 1999.

5. 24th Annual West Coast Biological Sciences Undergraduate Research Conference. “Complement Activation

During VAD Circulation”. Irvine, CA. May 1999.

6. 30th Annual Western Student Medical Research Forum. “The Effect of Pramipexole in a Rodent Model of

Early Parkinson’s Disease”. Carmel, CA. February 2002.

7. Colloquium in Spinal Muscular Atrophy (International). “Histone Deacetylase Inhibitors as a Treatment for

Spinal Muscular Atrophy”. Evry, France. May 2003.

8. Howard Hughes Medical Institute Research Scholars Scientific Presentations. “The Effect of Valproic Acid

on Histone Acetylation and SMN Expression in Spinal Muscular Atrophy Cell Lines”. Bethesda, MD. May

2003.

9. 37th Critical Care Congress, Society of Critical Care Medicine. "Mortality and prognostic factors of patients

with hematopoietic stem cell transplants admitted to the intensive care unit". Honolulu, HI. February 2008.

10. UCLA Pulmonary Grand Rounds. “Aggressive ICU Care: When do we stop?” Los Angeles, CA. October

2009.

11. Pediatric Critical Care, Guest Lecturer. “Aggressive ICU Care”. Los Angeles, CA. January 2010.

12. Chest 2010. “Giant Right Upper Lobe Bulla Causing Mass Effect on the Right Ventricle”. Vancouver,

Canada. November 2, 2010.

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13. UCLA Pulmonary Grand Rounds. “Futile Treatment in the UCLA ICUs: How Much and How Often?” Los

Angeles, CA. November 2012.

14. UCLA Ethics Committee Guest Speaker. “The Frequency and Cost of Futile Critical Care at UCLA”. Los

Angeles, CA. May 2013.

15. Lecture for Fellows “Ethics in the ICU”. Los Angeles, UCLA. August 2013, June 2014, Jan 2015, Dec

2016, Feb 2017, Jan 2018.

16. American Society for Bioethics and Humanities Annual Meeting. “The Frequency and Cost of Futile

Treatment in Critical Care”. Atlanta, Georgia. October 25, 2013.

17. Chest 2013. “The Opportunity Cost of Futile Treatment in the Intensive Care Unit”. Chicago, IL. October

28, 2013.

18. UCLA Nursing Grand Rounds Guest Speaker. “The Frequency and Cost of Futile Treatment in Critical

Care.” Los Angeles, CA. January 16, 2014.

19. American Thoracic Society 2014 International Conference. “Differences Between Attendings' And Fellows'

Perceptions of Inappropriate Treatment in the Intensive Care Unit” Mini-Symposium in ICU Utilization and

Outcomes. San Diego, CA. May 18, 2014.

20. UCLA School of Medicine, Foundations Week for 4th Year Medical Students. “Ventilator Management

Skills”. July 2014 and July 2015.

21. CHEST 2014. Featured speaker for the Palliative and End-of-Life Care Network Steering Committee at the

ACCP. “The Cost of ICU Care Perceived to be Futile”. Austin, CA. October 27, 2014.

22. UCLA-Harbor Pulmonary Grand Rounds, invited speaker. “Futile Treatment in the ICU”. Torrance, CA.

January 21, 2015.

23. Plenary Session Speaker at UCLA Department of Medicine Research Day. “Quantifying and Understanding

Inappropriate Treatment in the ICU”. UCLA. October 3, 2015.

24. UCLA Department of Medicine Grand Rounds. “Quantifying and Understanding Inappropriate Treatment in

the ICU”. Los Angeles, CA. August 31, 2016.

25. American Society for Bioethics and Humanities Annual Meeting. “Understanding Factors Contributing to

Inappropriate Critical Care: A Mixed-methods Analysis of Medical Record Documentation”. Washington,

DC. October 9, 2016.

26. UCLA Ethics Committee Guest Speaker. “Blood Products Provided to Patients Receiving Inappropriate

Critical Care”. Los Angeles, CA. November 2017.

27. UCLA Ethics Committee Guest Speaker. “Improving End of Life Care in the ICU: 3 Wishes Project”. Los

Angeles, CA. March 27, 2018.

28. Multi-Center 3 Wishes Research Retreat. “3 Wishes Project: The UCLA Experience”. Muskoka, Ontario,

Canada. July 20, 2018.

29. UCLA Department of Medicine Grand Rounds. “3 Wishes Project: The UCLA MICU Experience”. Los

Angeles, CA. August 15, 2018.

30. CSU Institute on Palliative Care. “Seed Grant Presentation: Improving the EOL Experience for Older

Patients in the ICU”. San Diego, CA. October 12, 2018

31. UCLA Division of Geriatrics Grand Rounds. Guest Speaker. “3 Wishes Project”. Los Angeles, CA.

December 14, 2018.

32. Society of Critical Care Medicine 48th Annual Critical Care Congress. “The Prevalence of Inappropriate

Critical Care Has Decreased Over Time”. San Diego, CA. February 19, 2019.

33. UCLA Palliative Care Symposium. Keynote speaker along with Peter Phung and Rayna Ewer. “3 Wishes

Project: Changing EOL Care at UCLA”. Los Angeles, CA. April 5, 2019.

34. Schwartz Compassion in Action Conference. Panel discussion along with Pattie Jakel, Peter Phung, and

Yuhan Kao. “The 3 Wishes Program: Making a Difference for Patients and Families”. Boston, MA.

September 10, 2019.

35. American Society for Bioethics and Humanities Annual Meeting. “Perspectives of Surrogate Decision

Makers of Patients Who Received Inappropriate Critical Care”. Pittsburgh, PA. October 25, 2019.

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36. American Society for Bioethics and Humanities Annual Meeting. “Improving End of Life Care in the ICU:

the 3 Wishes Project”. Pittsburgh, PA. October 26, 2019.

REVIEWER FOR:

Journal of Pain and Symptom Management

Critical Care

American Journal of Critical Care

Critical Care Medicine

Journal of Medical Ethics

Scientific Reports – Nature

PLOS One (July 2018)

Journal of General Internal Medicine (March 2019)

Journal of Palliative Medicine (July 2019, Sept 2019)

PUBLICATION/BIBLIOGRAPHY

RESEARCH PAPERS

RESEARCH PAPERS (PEER REVIEWED)

A. RESEARCH PAPERS - PEER REVIEWED

1. Chen JC, Huynh TN, Serna DL, Sun CP, Ha HP, Steward E, Webster S, Brenner M. Alternative

pathway of complement is activated during ventricular assist. J Investig Med. 1999. 47:502-6

2. Sumner CJ, Huynh TN, Markowitz JA, Perhac JS, Hill B, Coovert DD, Schussler K, Chen X, Jarecki J,

Burghes AHM, Taylor JP, Fischbeck KH. Valproic acid increases SMN levels in spinal muscular

atrophy patient cells. Annals of Neurology. 2003. 54:647-654.

3. Kernochan LE, Russo ML, Woodling NS, Huynh TN, Avila AM, Fischbeck KH, Sumner CJ. The role

of histone acetylation in SMN gene expression. Human Molecular Genetics. 2005. 14(9):1171-82

4. Huynh TN, Weigt SS, Belperio JA, Territo M, Keane MP. Outcome and prognostic indicators of

patients with hematopoietic stem cell transplants admitted to the intensive care unit. J of

Transplantation. 2009. Article ID 917294. PMCID: PMC2809022

5. Huynh TN, Weigt SS, Sugar CA, Shapiro SS, Kleerup EC. Prognostic factors and outcomes of patients

with pulmonary hypertension admitted to the intensive care unit. Journal of Critical Care. 2012 Dec;

27(6):739e7-739e13.

6. Huynh, TN, Kleerup EC, Wiley JF, Savitzky TD, Guse D, Garber BJ, Wenger NS. The Frequency and

Cost of Treatment Perceived to be Futile in Critical Care. JAMA Internal Medicine. 2013 Nov

11;173(20):1887-94

7. Huynh TN, Walling AM, Le TX, Kleerup EC, Liu H, Wenger NS. Factors associated with terminal

withdrawal of mechanical ventilation and time to death after withdrawal. Journal of Palliative Medicine.

2013. Nov 16(11):1368-74. PMCID: PMC3822388

8. Huynh TN, Kleerup EC, Prince R, Wenger NS. The opportunity cost of futile treatment in the intensive

care unit. Critical Care Medicine. 2014 Sep;42(9):1977-82. PMCID: PMC413470

9. Neville TH, Wiley JF, Holmboe ES, Tseng CH, Vespa P, Kleerup EC, Wenger NS. Differences between

attendings’ and fellows’ perceptions of futile treatment in the intensive care unit: implications for

training. Academic Medicine. 2015 Mar;90(3):324-30. PMCID: PMC4339400

10. Neville, TH, Wiley JF, Yamamoto M, Flitcraft M, Anderson B, Curtis JR, Wenger NS. Concordance of

nurses and physicians on whether critical care patients are receiving futile treatment. Am J Crit Care.

2015 Sep;24(5):403-10.

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11. TG Bentley, JT Cohen, EB Elkin, J Huynh, A Mukherjea, TH Neville, M Mei, R Copher, R Knoth, I

Popescu, J Lee, JM Zambrano, MS Broder. Validity and Reliability of Value Assessment Frameworks

for New Cancer Drugs. Value in Health. 2017 Feb; 20: 200-205.

12. Bentley TGK, Cohen JT, Elkin EB, Huynh J, Mukherjea A, Neville TH, Mei M, Copher R, Knoth R,

Popescu I, Lee J, Zambrano JM, Broder MS. Measuring the Value of New Drugs: Validity and

Reliability of 4 Value Assessment Frameworks in the Oncology Setting. J Manag Care Spec Pharm.

2017 Jun;23(6-a Suppl):S34-S48.

13. Neville TH; Ziman A; Wenger NS. Blood Products Provided to Patients Receiving Inappropriate

Critical Care. Journal of Hospital Medicine. 2017 Sep;12(9):739-742.

14. Neville TH, Tarn DM, Yamamoto M, Garber B, Wenger NS. Understanding Inappropriate Critical Care:

A Qualitative Analysis of Medical Record Documentation. Journal of Palliative Medicine. 2017

Nov;20(11):1260-1266.

15. Neville TH, Yamamoto M, Wiley J, Wenger NS. Resource Utilization and Description of Patients

Perceived as having Received Inappropriate Critical Care. Intensive & Critical Care Nursing. 2019 Oct;

54:29-33.

16. Neville TH, Agarwal N, Swinton M, Phung P, Xu X, Kao Y, Seo J, Granone MC, Hjelmhaug K, Hainje

J, Pavlish C, Clark F, Cook DJ. Improving End of Life Care in the Intensive Care Unit: Clinicians’

Experiences with the 3 Wishes Project. Journal of Palliative Medicine. 2019 Dec;22(12):1561-1567

(Published online, ahead of print in July 2019).

17. Vanstone M, Neville TH, Clarke F, Swinton M, Sadik M, Takaoka A, Smith O, Baker A, LeBlanc A,

Foster D, Dhingra V, Phung P, Xu X, Kao Y, Heels-Ansdell S, Tam B, Toledo F, Boyle A, Cook D.

Compassionate End-of-Life Care: Mixed-methods multi-site evaluation of the 3 Wishes Project. Annals

of Internal Medicine. Published online, ahead of print, November 2019.

18. D Chang, J Parrish, N Kamangar, J Liebler, M Lee, T Neville. Time Limited Trials Among Critically-ill

Patients with Advanced Medical Illnesses: Protocol to Reduce Non-Beneficial Intensive Care Unit

Treatments. JMIR Research Protocols. 2019 Nov 25;8(11):e16301.

19. A Takaoka, K Honarmand, M Vanstone, B Tam, O Smith, A Baker, A LeBlanc, M Swinton, TH

Neville, F Clarke, J Hancock, S McMullen, M Meade, T Rose, S Arora, D Cook. Organ Donation at the

End of Life: Experiences from the 3 Wishes Project. Journal of Intensive Care Medicine. Published

online, ahead of print, Jan 2020.

B. RESEARCH PAPERS - PEER REVIEWED (IN PRESS):

C. RESEARCH PAPERS - PEER REVIEWED (SUBMITTED)

1. TH Neville, JF Wiley, M Kardouh, JR Curtis, M Yamamoto, NS Wenger. Inappropriate Critical Care is

Decreasing.

2. A Takaoka, M Vanstone, TH Neville, S Goksoyr, M Swinton, FJ Clarke, O Smith, A LeBlanc, D Foster,

Y Kao, X Xu, N Hoad, F Toledo, DJ Cook. Continued Connections: Family and Clinician Experiences

of Sympathy Cards in the 3 Wishes Project.

3. Vanstone, M; Sadik, M; Smith, O; Neville, T; LeBlanc, A; Boyle, A; Clarke, F; Swinton, M; Takaoka,

A; Toledo, F; Baker, A; Phung, P; Cook, D. Building Organizational Compassion Amongst Teams

Delivering End-of-Life Care in the ICU: The 3 Wishes Project.

4. TH Neville, DM Tarn, C Pavlish, N Wenger. Community Perspective of Potentially Inappropriate

Treatment

5. KE Schwab, W Simon, M Yamamoto, A Dermenchyan, X Xu, Y Kao, A Zider, F Shaikh, B Garber, E

Lee, Z Anklesaria, S Tomova, A Ramsey, TH Neville. Rapid Mortality Review in the Intensive Care

Unit: A Novel In-Person Multidisciplinary Improvement Initiative.

RESEARCH PAPERS (NON-PEER REVIEWED): none

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CHAPTERS:

1. Walling, AM, Neville, TH, Moran, D, Wenger NS. “End-of-Life Care” in Modern Thoracic Oncology.

Cameron et al. World Scientific, p270-285, 2018

LETTERS TO THE EDITOR:

1. Neville, TH, Wenger NS. Reply to “Of Course Futile Care Is Wasteful. Are We Ready to Act on this

Knowledge?” Critical Care Medicine. 2015 Feb; 43(2): e59. PMC4323168

2. Neville, TH, Wenger NS. Reply to: "Judgment of Futile Care in the ICU.” Critical Care Medicine.

2015 May; 43(5): e152. PMCID: PMC4431641

REVIEWS: none

EDITORIALS:

1. Neville, TH. Only Human. Intensive Care Med. 2015 Jan;41(1):139-40

2. Neville, TH. 3 Wishes: Transforming Death in the ICU. CSU Institute for Palliative Care Blog.

https://csupalliativecare.org/3-wishes/ November 2018.

CASE REPORTS – PEER-REVIEWED

1. Huynh TN, Yochim SE, Chang S, Kamangar N. A Case in Point: Silicone-induced pneumonitis. J of

Respiratory Diseases. 2005. 26(11): 480-482.

2. Garber B, Albores J, Wang T, Neville TH. A plasmapheresis protocol for refractory pulmonary alveolar

proteinosis. Lung. 2015 Apr;193(2):209-11

PAPERS IN PREPARATION (RESEARCH COMPLETED)

None

ABSTRACTS 1. Huynh TN, Serna DL, Ha HP, Parhizgar S, Powell LL, Steward E, Webster S, Chen JC. Alternative

pathway of complement is activated during ventricular assist. J Investig Med. 1999. 47: 4A.

2. King B, Serna DL, Huynh T, Wang J, Chen JC. Complement-mediated PF4 release contributes to

inflammation and thromboembolism during in vitro VAD circulation. ASAIO. 1999. 45:149.

3. Serna DL, Mirhadi AJ, Huynh TN, King BO, Sun C, Webster S, Chen JC. Complement mediates

neutrophil degranulation during Ventricular Assist Circulation. ASAIO. 1999. 45:150.

4. King BO, Serna DL, Huynh TN, Wang D, Steward E, Chen JC. Release of C1 Inhibitor from platelet alpha

granules regulates complement activation in an in vitro model of ventricular assist. Society of

Cardiovascular Anesthesiologists. 1999. SCA1-SCA126:88.

5. Mirhadi AJ, Serna DL, Huynh TN, Wang J, Webster S, Chen JC. Neutrophil degranulation during in vitro

ventricular assist circulation. J Investig Med. 1999. 47:4A.

6. T Huynh, HP Ha, DL Serna, JC Chen. Excellence in Research Scientific Talk and Poster Sessions.

“Alternative Pathway of Complement is Activated During Ventricular Assist”. UC Irvine, CA. April 1999.

7. King BO, Jones BU, Serna DL, Wang J, Tran L, Huynh T, Wang D, Duhaylongsod FG, Sun C, Chen JC.

Tirofiban administration attenuates platelet – neutrophil conjugation, but not the inflammatory response

during ventricular assist device circulation. ASAIO/CVST. 2000.

8. T Huynh, A Mehta, MF Chesselet. Josiah Brown Poster Session for Short-Term Training Program, UCLA

School of Medicine. “The Effect of Pramipexole in a Rodent Model of Early Parkinson’s Disease”. Los

Angeles, CA. August 2002.

9. TN Huynh, CJ Sumner, KH Fischbeck. “Valproic Acid Increases SMN Expression in Spinal Muscular

Atrophy Cell Lines”. American Medical Student Association 53rd Annual Convention Poster Session.

Washington, DC. March 2003.

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10. TN Huynh, CJ Sumner, KH Fischbeck. “Valproic Acid Increases SMN mRNA and Protein Levels in

Spinal Muscular Atrophy Cell Lines”. American Academy of Neurology 55th Annual Meeting Poster

Presentation. Honolulu, HI. March 2003.

11. TN Huynh, CJ Sumner, KH Fischbeck. “Valproic Acid Increases SMN Expression in Spinal Muscular

Atrophy Cell Lines”. National Institute of Neurological Disease and Stroke Annual Retreat Poster Session.

Warrenton, VA. April 2003.

12. TN Huynh, CJ Sumner, KH Fischbeck. “Valproic Acid Increases SMN Expression in Spinal Muscular

Atrophy Cell Lines”. Howard Hughes Medical Institute Meeting of Medical Fellows Poster Session.

Chevy Chase, MD. May 2003.

13. Kernochan LE, Huynh TN, Fischbeck KH, Sumner CS. Valproic acid effects on histone acetylation in the

survival motor neuron (SMN) promoter. Neurology. 2004. 62: Supp 5:30A.

14. ME Billings, T Huynh, MP Keane. The Use of Brain Natriuretic Peptide as a Proxy for Pulmonary

Capillary Wedge Pressure in the Septic Patient. American Thoracic Society. 2006. A295.

15. TN Huynh, M Territo, MP Keane. Outcome and Characteristics of Patients with Hematopoietic Transplants

Admitted to the Intensive Care Unit. American Thoracic Society. 2007. A216.

16. TN Huynh, SS Weigt, JA Belperio, M Territo, MP Keane. Mortality and prognostic factors of patients with

hematopoietic stem cell transplants admitted to the intensive care unit. Society of Critical Care Medicine.

12/2007. A29.

17. TN Huynh, SS Weigt, M Territo, MP Keane. “Outcomes of Patients with Hematopoietic Transplants

Admitted to the Intensive Care Unit”. American Thoracic Society International Conference. San Francisco,

CA. May 2007.

18. TN Huynh, SS Weigt, SS Shapiro, EC Kleerup. “Characteristics and Prognostic Factors of Patients with

Pulmonary Hypertension Admitted to the Medical ICU”. American Thoracic Society International

Conference. New Orleans, LA. May 2010.

19. TN Huynh, AM Walling, TX Le, EC Kleerup, NS Wenger. “Characteristics Associated with Terminal

Withdrawal of Mechanical Ventilation and Time to Death”. Chest 2011. Honolulu, HI. October 2011.

20. TN Huynh, EC Kleerup, D Guse, NS Wenger. “Quantifying Futile Treatment in the Intensive Care Unit”.

Department of Medicine Research Day. UC Los Angeles, CA. October 2012.

21. TN Huynh, EC Kleerup, D Guse, NS Wenger. “Quantifying Futile Treatment in the Intensive Care Unit”.

Society of Critical Care Medicine Critical Care Congress. San Juan, PR. January 2013.

22. NS Wenger, EC Kleerup, TN Huynh. The Prevalence, Predictors, and Cost of Futile Treatment in the

Intensive Care Unit. Society of General Internal Medicine. Denver Colorado. April 2013.

23. TN Huynh, EC Kleerup, NS Wenger. The Cost of Futile Treatment. American Thoracic Society 2013

International Conference. “Dollars and Sense” Poster Discussion Session. Philadelphia, PA. May 2013.

24. Wiley, JF, Huynh, TN, Wenger, NS. “Methods for intuitive presentations of hierarchical categorical

models: An example predicting futile treatment in critical care”. Modern Modeling Methods. May 2013.

25. TN Huynh, EC Kleerup, P Raj, NS Wenger. “The Opportunity Cost of Futile Treatment”. Department of

Medicine Research Day. UC Los Angeles, CA. October 2013.

26. J Albores, T Huynh. “An 89-Year Old Man with a Broken Lung and a Broken Heart”. American Thoracic

Society 2014 International Conference. Thematic Poster Session. San Diego, CA. May 2014.

27. TH Neville, NS Wenger. “Nurse and physician concordance on whether critical patients are receiving

treatment perceived to be futile: Opportunity for Collaboration”. American Society of Bioethics and

Humanity. San Diego, CA. October 2014.

28. TH Neville, I Smith, J Bando, M Yamamoto, T Prendergast, K Lorenz, S Ahluwalia. “Implementation and

Use of an ICU Family Meeting Template”. American Thoracic Society 2015 International Conference.

Denver, CO. May 2015.

29. TH Neville, DM Tarn, NS Wenger. “Understanding Inappropriate Critical Care: A Qualitative Analysis of

Medical Record Documentation”. UCLA Department of Medicine Research Day. Los Angeles, CA.

October 2015.

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30. TH Neville, DM Tarn, M Yamamoto, BJ Garber, NS Wenger. “Understanding Inappropriate Critical

Care: A Qualitative Analysis of Medical Record Documentation”. American Thoracic Society 2016

International Conference. San Francisco, CA. May 2016.

31. TH Neville, A Ziman, NS Wenger. “Blood Products Provided to Patients Receiving Inappropriate Critical

Care”. Society of Critical Care Medicine. Honolulu, HI. January 2017.

32. AD Zider, W Simon, S Vangala, A Dermenchyan, TH Neville. “Introduction of rapid mortality review in

the medical intensive care unit: methods and initial results”. American Thoracic Society International 2017

Conference. Washington, DC. May 2017.

33. TH Neville, M Yamamoto, J Wiley, NS Wenger. “Resource Utilization and Description of Patients

Perceived as having Received Inappropriate Critical Care”. UCLA Department of Medicine Research Day.

Los Angeles, CA. October 2017.

34. BJ Garber, W Simon, OO Amubieya, TH Neville, “Rapid Mortality Review as a Tool for Resident

Debriefing in the Intensive Care Unit”. American Thoracic Society 2018 International Conference. San

Diego, CA. May 2018.

35. TH Neville, M Yamamoto, J Wiley, NS Wenger. “Resource Utilization and Description of Patients

Perceived as having Received Inappropriate Critical Care”. American Thoracic Society 2018 International

Conference. San Diego, CA. May 2018.

36. N Agarwal, J Seo, P Phung, X Xu, Y Kao, M Granone, K Hjelmhaug, J Hainje, D Cook, M Swinton, TH

Neville. “The Effect of the 3 Wishes Project on Clinicians: Making Work Meaningful”. UCLA Department

of Medicine Research Day. Los Angeles, CA. May 2018. (Awarded 2nd place in poster competition).

37. TH Neville, JF Wiley, M Kardouh, JR Curtis, M Yamamoto, NS Wenger. “Inappropriate Critical Care is

Decreasing”. UCLA Department of Medicine Research Day. Los Angeles, CA. May 2018.

38. Agarwal N, Phung O, Xu X, Kao Y, Hjelmhaug K, Ramsey A, Neville TH. “The 3 Wishes Project: A

Feasible Intervention to Improve End of Life Care in the Intensive Care Unit at UCLA”. CHEST 2018.

San Antonio, TX. Oct 2018. (Awarded Top 5 Posters)

39. Takaoka A, Clarke F, Hoad N, Swinton M, Goksoyr S, Leblanc A, Foster D, Lockington J, Dhingra V,

Neville T, Xu X, Kao Y, Phung P, Smith O, Vanstone M, Cook D. “Post-Mortem Expressions of

Compassion: A Secondary Qualitative Analysis of Family and Clinician Experiences of Sympathy Cards in

the 3 Wishes Project”. Canadian Critical Care Forum 2018; Toronto, Canada. Nov 2018.

40. F. Clarke, M. Swinton, O. Smith, A. Baker, G. Sandhu, J. Hodder, M. Santos, J. Lockington, V. Dhingra,

A. LeBlanc, D. Foster, S. Goksoyr, A. Takaoka, M. Vanstone, N. Hoad, T. Neville, P. Phung, X. Xu, Y.

Kao, M. Granone, K. Buck, F. Toledo, A. Woods, A. Boyle, B. Sheppard, D. Heels-Ansdell, B. Tam, M.

Azad, J. Dionne, J. Centofanti, S. Arora, M. Shears, J. Piticaru, D. Cook. “Compassionate End of Life Care

in the ICU: Multicenter Evaluation of the Scalability, Transferability, Affordability, Sustainability, and

Value of the 3 Wishes Project”. Canadian Critical Care Forum 2018; Toronto, Canada. Nov 2018.

41. J Seo, N Agarwal, P Phung, X Xu, Y Kao, M Granone, D Cook, K Hjelmhaug, J Hainje, M Swinton, TH

Neville. “The Effect of the 3 Wishes Project on Clinicians from Survey Data: Making Work Meaningful”.

SCCM 48th Annual Critical Care Congress. San Diego, CA. February 2019.

42. F Clarke, N Hoad, F Toledo, O Smith, D Foster, A Leblanc, J Lockington, G Sandhu, J Hodder, M Santos,

I Khalid, X Xu, Y Kao, M Granone, P Guyatt, P Phung, J Arthur, B Reeve, W Dechert, T Neville. “What

Do Dying Patients, Their Families, and Clinicians Wish for? Findings from the 3 Wishes Project”. SCCM

48th Annual Critical Care Congress. San Diego, CA. February 2019.

43. F Clarke, T Neville, M Swinton, O Smith, D Foster, F Toledo, N Hoad, A Takaoka, M Shears, K Buck, C

Lee, R Piacentino, A Leblanc, J Lockington, S Goksoyr, X Xu, Y Kao, M Granone, M Vanstone D, D

Heels-Ansdell, A Baker, V Dhingra, P Phung, D Cook. “Patient and Family Engagement at the End of

Life: The Multicenter 3 Wishes Project”. SCCM 48th Annual Critical Care Congress. San Diego, CA.

February 2019.

44. K Hjelmhaug, J Hainje, Y Kao, X Xu, N Agarwal, J Seo, P Phung, TH Neville. “Effect of the 3 Wishes

Project in the MICU: Increasing Clinician Morale”. AACN Leadership Symposium: Our Voice, Our

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Strength. Los Angeles, CA. February 2019 and 6th National Nursing Ethics Conference. Los Angeles, CA.

March 2019.

45. T Neville, DM Tarn, C Pavlish, NS Wenger. “Community Perspective of Medical Futility”. 2019 ATS

International Conference. Dallas, TX. May 2019.

46. W Toppen, A Ramsey, D Markovic, TH Neville, R Saggar, D Berlin, I Barjaktarevic. “Risks of

endotracheal intubation in decompensated acute right heart failure. 2019 ATS International Conference”.

Dallas, TX. May 2019.

47. AL Ramsey, A Maller, X Xu, Y Kao, TH Neville. “Improving Outside Hospital Transfers in the Medical

Intensive Care Unit: A Quality Improvement Initiative”. 2019 ATS International Conference. Dallas, TX.

May 2019.

48. K Schwab, W Simon, AL Ramsey, F Shaikh, E Lee, X Xu, Y Kao, M Yamamoto, TH Neville. “ICU

Mortality Review: Identifying Areas for Quality Improvement and Affecting Systemic Change”. 2019 ATS

International Conference. Dallas, TX. May 2019.

49. Clarke FJ, Takaoka A, Hoad N, Azad M, Neville TH, Hjelmhaug K, Bear D, Reitzenstein S, Bell A, Smith

O, LeBlanc A, Davidson F, Levesque K, Tam B, McMullen S, Hancock J, Reeve B, Dechert W, Swinton

M, Cook DJ. Artistic Creations as Wishes at the End-of-Life in the 3 Wishes Project. SCCM 2020 Critical

Care Congress. Feb 2020.

50. Takaoka A, Honarmand K, Vanstone M, Tam B, Clarke F, Swinton M, Smith O, Baker A, Hodder J,

LeBlanc A, Dhingra V, Foster D, Hancock J, McMullen S, Meade M, Arora S, Hoad N, Neville T, Phung

P, Cook D. Organ Donation at the End of Life: Experiences from the 3 Wishes Project. SCCM 2020

Critical Care Congress. Feb 2020.

51. D Bear, P Phung, D Karlin, P Jakel, J Hainje, K Hjelmhaug, A Bell, R Bank, G Peterson, F Clarke, D

Cook, TH Neville. “How to Strategically and Successfully Expand a Palliative Care Initiative Hospital-

Wide”. American Academy of Hospice and Palliative Medicine. San Diego, CA. March 2020.

52. TH Neville, P Phung, D Bear, N Agarwal, X Xu, Y Kao, K Hjelmhaug, J Hainje, M Swinton, P Jakel, A

Bell, R Ewer, K McCann, D Karlin, L Roque, N Sanaee, J Do, M Donovan, B Hardin-Wilke, L Shachat, T

Wang, C Sheth, D Cook. “Improving End-of Life Care: Implementation and Evaluation of the 3 Wishes

Project in an American Health System”. 2020 State of the Science in Hospice and Palliative Care Meeting.

San Diego, CA. March 2020.

MEDIA (SELECTED)

RADIO AND TELEVISION (Interviews or Research Quoted In)

KNX 1070AM. Caring for patients who may never recover spreading ICU’s thin. August 20, 2014.

KPCC 89.3FM. “Airtalk with Larry Mantle”. Is closer scrutiny of “futile care” necessary to provide better ICU

care? August 27, 2014.

KCRW 89.9FM. Futile Care: Should you have the right to receive whatever care you want? Sept. 29, 2014.

ABC7 featured the UCLA Health 3 Wishes Project, which provides dignity to dying patients. Thanh Neville,

MD, critical care specialist and medical director of the project, and a patient family were featured. The story

also ran on www.wndu.com/, www.9and10news, www.wfmz.com, www.wpsd.com, www.abc12.com,

https://abc30.com/, and www.wearegreenbay.com. March and April 2019.

MAGAZINE AND NEWSPAPER (Interviews or Research Quoted)

MedPage Today, LA Times, AMN Healthcare, NY Times, Bloomberg News, Healthday News, Businessweek,

Science Daily, Health Leaders, Life Science, and Sierra Sun Times. Futile care in the ICU a common, costly

occurrence. September 2013.

Reuters Health, Science Codex, Science 2.0, Science Daily, MedicalXpress, News-Medical, Dot Med, MedPage

Today, HealthDay News, Insurance News Net, Health Pro News, Sierra Sun Times, Health Canal, Fierce