mmsc programme a5 1509 - alti sites
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www.canceropole-paca.fr
FINAL PROGRAM
3 & 4 OCTOBER 2016
3rd International Symposium of Skin Cancers
Hotel Le Saint-Paul NICE, FRANCE
Skin cancer is a widely spread disease, which causes patient death and arises from both epithelial and non- epithelial cells.
Deciphering the molecular mechanisms of skin cancers development will allow discovery of new molecular targets for therapeutic intervention.
To this aim, researchers have developed, during the last decades, innovative mouse models of skin cancers that bring new insights in many aspects of this life threatening disease.
This symposium will bring together internal multidis-ciplinary experts, including biologists, clinicians and physicians, in skin cancers and will provide latest dis-covery using innovative mouse models of skin cancers development and corroborate their finding with the corresponding human diseases.
3 & 4 OCTOBER 2016
3rd International Symposium of Skin Cancers
Hotel Le Saint-Paul NICE, FRANCE
EDITORIAL
F. Calvo (CRUK, United Kingdom)P. Coulombe (Johns Hopkins, Baltimore, USA)E. Farge (Curie Institute, France)M-D. Galibert (IGDR, France)D. Hanahan (EPFL, Switzerland)E. Hoste (VIB, Belgium)G. J. Inman (University of Dundee, United Kingdom)T. S. Kupper (Brigham and Woman’s Hospital, Boston, USA)L. Larue (Curie Institute, France)
B. Lichtenberger (Medical University of Vienna, Austria)R. Marais (Cancer Research UK, United Kingdom)J. C. Marine (VIB, Belgium)R-M. Mège (IJM, France)C. Niessen (CECAD, Germany)T. Passeron (CHU Nice, France)V. Sanz-Moreno (KCL, United Kingdom)B. Weigelin (RIMLS, The Netherlands)S. Wickstrom (Max Planck Institute for Biology of Aging, Germany)
INVITED SPEAKERS
MONDAY OCTOBER 3RD
08:30 Registration Opening
Chairmen: L. Le Cam & C. Niessen
Fibroblast heterogeneity in the skin and cancer. B. Lichtenberger (Austria)
Regulation of cell and tissue architecture in skin barrier function, inflammation and cancer. C. Niessen (Germany)
Modelling cutaneous squamous cell carcinoma. G. J Inman (United Kingdom)
11:00 Coffee break
Chairmen: C. Gaggioli, R. Marais & S. Tartare-Deckert
Relevance to humans of mouse models for the melanocyte lineage. L. Larue (France)
Emerging roles of the actomyosin cytoskeleton in melanoma biology: from 3D systems to mouse models. V. Sanz-Moreno (United Kingdom)
12:30 Lunch
Chairmen: C. Gaggioli, R. Marais
& S. Tartare-Deckert
What can we learn about melanomagenesis from mice? R. Marais (United Kingdom)
Integrative genomic analysis of genetically-induced mouse melanoma lesions identifies novel melanoma tumor suppressors. J-C. Marine (Belgium)
Selected talks Development of an orthotopic mice
model to analyse the establishment of the pre-metastatic niche of melanoma in the lymph node. V. Prodhomme (France)
ß-catenin inhibits melanocyte migration after UVB irradiation. J. Bertrand (France)
FES tyrosine kinase is a tumor suppressor in melanoma. P. de Sepulveda (France)
18:00 Keynote lecture D. Hanahan (Switzerland)
18:45 Welcome reception
16:3018:00 POSTER SESSION & coffee break
09:3011:00 CARCINOMAS
SESSION I
11:1512:30 MELANOMA
SESSION II
14:3016:30 MELANOMA
SESSION II
PRELIMINARY PROGRAM
Chairmen: C. Gaggioli, E. Hoste & M. Deckert
Mechanisms of wound-induced skin tumor formation. E. Hoste (Belgium)
Keratins regulate inflammation and immunity in skin epithelia: relevance to cancer and related diseases. P. Coulombe (USA)
TBA. TS. Kupper (USA)
Selected talks Targeting Sphingosine Kinase-1
enhances anti-melanoma immune response and improves efficacy of immune checkpoint blockade. C. Imbert (France)
NKp46+ innate lymphoid cells display specific gene and functional signature at each stage of skin carcinogenesis. C. Luci (France)
11:00 Coffee break
Chairmen: G. Meneguzzi & T. Passeron
Regulation of skin pigmentation. T. Passeron (France)
The skin response to UV exposure. M-D. Galibert (France)
Selected talk Role of the Lyn tyrosine kinase
in the regulation of psoriasis. S. Marchetti (France)
12:30 Lunch
Chairmen: E. Farge & C. Feral
Intravital imaging of melanoma cell invasion: principles of interface guidance along tissue highways. B. Weigelin (The Netherlands)
Biomechanical regulation of cell fate. S. Wickstrom (Germany)
Selected talks Sphingolipid regulation of integrin
mechanosensing by CD98hc (SLC3A2). E. Boulter (France)
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis. M. Lacroix (France)
15:30 Coffee break
Chairmen: E. Farge & C. Feral
Mechanobiology of cancer-associated fibroblasts. F. Calvo (United Kingdom)
Mechanosensitivity of junctional beta-catenin: from mesoderm mechanotransductive evolutionary origins to tumorigenic mechanical induction. E. Farge (France)
Influence of the mechanical properties of the environment on cell migration and wound healing. R-M. Mège (France)
17:30 End of the meeting
TUESDAY OCTOBER 4TH
09:0011:00
SKIN MICROENVIRONMENT,INFLAMMATION & IMMUNITY
SESSION III
11:1512:30 HUMAN SKIN PHYSIOPATHOLOGY
SESSION IV
14:0015:30
PHYSICS OF MICROENVIRONMENT
SESSION V
16:0017:30
PHYSICS OF MICROENVIRONMENT
SESSION V
PRELIMINARY PROGRAM
Chloé Feral, IRCAN, Nice
Cédric Gaggioli, IRCAN, Nice
Laurent Le Cam, IRCM, Montpellier
Sophie Tartare-Deckert, C3M, Nice
Ariane Leroy, Cancéropôle PACAMarseille, France Tel.: +33 (0)4 91 32 47 [email protected]
3 & 4 OCTOBER 2016
3rd International Symposium of Skin Cancers
Hotel Le Saint-Paul NICE, FRANCE
SCIENTIFIC COMMITTEE
ORGANIZING COMMITTEE
GENERAL INFORMATIONCongress venueHotel Le Saint-Paul29, Bd Franck Pilatte 06300 Nice, FranceTel.: +33 (0)4 93 89 39 57
Contact & organizationCom&Co, Rodolphe Bayle15, Bd Grawitz 13016 Marseille, FranceTel.: +33 (0)6 35 32 75 57 / +33 (0)4 91 09 70 53Fax: +33 (0)4 96 15 33 08Email: [email protected]
www.canceropole-paca.fr
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CALL FOR ABSTRACTSSubmission deadline: September 10th 2016 www.canceropole-paca.fr
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3 & 4 OCTOBER 2016
3rd International Symposium of Skin Cancers
Hotel Le Saint-Paul NICE, FRANCE
REGISTRATION FORM
REGISTRATION FEES
q Students Docs / Post-docs 90€
q Researchers / Industrials 120€
PAYMENTq By credit card (Visa / Mastercard / no other card)
On protected payment Paybox online form, directly on the website www.comnco.com. Please indicate your Name + MMSC 2016 in the part: “Additional details”
q By check enclosed (make check in euros payable in France to Com&Co)
q By bank transfer to Com&Co Bank Chaix - 41/43, Bd Peytral 13006 Marseille IBAN FR76 1017 8000 2600 2626 3880 380 BIC CCBPFRPPCHX
RETURN TO COM&CO BY:Post 15, Bd Grawitz 13016 Marseille, France
Fax +33 (0)4 96 15 33 08
Email [email protected]
Online www.canceropole-paca.fr