haridra (curcuma longa linn.) – a miraculous drug for anemia
TRANSCRIPT
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Pandya. World Journal of Pharmacy and Pharmaceutical Sciences
HARIDRA (CURCUMA LONGA LINN.) – A MIRACULOUS DRUG FOR
ANEMIA
Megha G. Pandya*
*Lecturer, Dept. of Kayachikitsa, Shri Gulabkunverba Ayurved Mahavidyalaya, Gujarat
Ayurved University, Jamnagar.
ABSTRACT
Panduroga can be correlated with Anemia on the ground of its similar
signs and symptoms. Panduroga (Anemia) is well described in
Ayurveda since ancient time including etiology, pathogenesis, clinical
features, prognosis, complications and management. Haridra
(Curcuma longa Linn.) of the family Zingiberaceae is commonly used
drug. Haridra (Curcuma longa Linn.) is used as anti-inflammatory,
cholagogue, hepatoprotective, blood-purifier, antioxidant, detoxifier
and regenerator of liver tissue, antiasthmatic, antiprotozoal, stomachic,
carminative etc. Here attempt was made to highlight role of drug
Haridra (Curcuma Longa Linn.) in the management of Anemia
(Pandu) as per ayurvedic as well as modern perspective. The data in
the present review have been organized in various sections according
to Ayurvedic view and with recent researches carried out on the drug.
KEY WORDS: Anemia, Curcuma longa, Haridra, Pandu.
INTRODUCTION
“Pandu Roga” can be correlated with Anemia on the ground of its similar signs and
symptoms. The meaning of word Pandu is pallor of the body[1]
or resembling the colour of
pollen of Ketaki flower along with yellow colour.[2]
Pandu has been well described in
Ayurveda since ancient times including etiology, pathogenesis, clinical features, prognosis,
complications and management. Anemia is defined as a haemoglobin concentration in blood
below the lower limit of the normal range for the age and sex of individual leads to
deficiency in the number of red blood cells or in the haemoglobin content of the blood,
resulting in pallor, shortness of breath and lack of energy.[3]
According to Ayurveda it is not
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
SJIF Impact Factor 5.210
Volume 4, Issue 11, 1565-1578 Research Article ISSN 2278 – 4357
Article Received on
10 Sep 2015,
Revised on 01 Oct 2015,
Accepted on 22 Oct 2015
*Correspondence for
Author
Dr. Megha G. Pandya
Lecturer, dept. of
Kayachikitsa, Shri
Gulabkunverba Ayurved
Mahavidyalaya, Gujarat
Ayurved University,
Jamnagar.
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restricted upto blood and blood forming haemopoietic system, but it is caused due to non-
sequential transformation of food into proper body components Rasa (plasma), Rakta
(blood) up to Shukra (semen) & Oja (the essence of the seven Dhatus or bodily tissues).
That‟s why Acharya Charaka[4]
has mentioned Panduroga as a disease of „Rasavaha Strota‟.
Panduroga is developed as a result of imbalance and variation of Tridoshas (Vata,Pitta,
Kapha) due to either Santarpanjanya (over nutrition) or Apatarpanjanya (under nutrition)
causes.
Panduroga can be overcome through the various traditional systems such as Ayurveda. There
are various herbal and herbo mineral formulations mentioned in Ayurvedic classics for the
management of Pandu. From the time of Atharvaveda, Haridra is being used as a medicine
for mankind. Turmeric (Curcuma longa) has been used for centuries in Ayurvedic medicine,
which amalgamate the medicinal goods of herbs with food. This astonishing herb has
established its way into the attention in the west because of its wide range of medicinal
benefits.[5]
Current research has focused on turmeric‟s antioxidant, hepatoprotective, anti-inflammatory,
anticarcinogenic, and antimicrobial properties, including hypoglycemic property. However,
reports on its antianemic properties are limited and therefore this review study seeks the
effect of C. longa on Anemia. This article focuses on one the antianemic activity of turmeric
with use of ancients and contemporary knowledge.
UNDERSTANDING OF PANDUROGA
Clinical features of Pandu develop from the depletion of Rasa Dhatu which in turn becomes
ineffective in the production of Rakta Dhatu. The decreased level of circulating Rasa and
Rakta Dhatu, which have the prime functions of nourishment and providing support to the
vital functions, gives rise to the symptoms like depletion of blood and flesh, fatigue, body
ache, palpitation, periorbital Oedema, anorexia, dyspepsia, fever, dyspnoea and fainting.[6]
MATERIAL AND METHODS
The data were collected from Ayurvedic as well as contemporary literatures and scientific
journals, books etc.
HARIDRA (CURCUMA LONGA LINN)
Turmeric (Haridra) is an auspicious beauty spot, daily applied on the forehead by Hindu
females. Application of turmeric paste to the bride is an essential procedure of Hindu
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rituals.[7]
Haridra (Curcuma longa Linn.) of the family Zingeberacae has esteemed medicinal
properties referred in Ayurveda and has been widely used in India since ancient times in
Ayurveda, turmeric has been well documented for its therapeutic potentials. The great sage
Acharya Charaka has categorized it is in various Dashemani (group of ten drugs) such as
Lekhaniya[8]
(scrapping herbs), Vishaghna[9]
(anti-toxin) and Kusthaghna[9]
(anti-dermatosis).
Acharya Sushruta has classified Haridra under Haridradi Gana[10]
, Tiktaskandha[11]
(group
of bitter drugs), Mustadi Gana[12]
, Lakshadi Gana[13]
Vataprashamana Gana (vata alleviating
group)[14]
and Shleshmaprashamana Gana (kapha alleviating group).[15]
Turmeric has been
used traditionally for almost every human ailment and many of these historic uses have been
scientifically validated with application in modern times.
SYNONYMS OF HARIDRA IN SANSKRITA[16]
Rajani, Nisha, Gauri, Krimighna, Vishaghni, Yoshitpriya, Kanchani, Varavarnini,
Hattavilasinsi, Aneshta, Dirgharaga, Hemaragi, Harita, Pitika, Ratrinamika, Shobha,
Suvarna, Shyama, Vara, Varangi, Varnadatri, Varnini, Yuvati, Gandhapalashika,
Mangalaprada, Mangalya, Pavitra, Tapasvini, Uma, Mehaghni, Jayanti
Botanical name: Curcuma longa Linn. (C. domestica Valeton.)
Family: Zingiberaceae.
Regional Names[17]
English: Turmeric
Assam; Haldhi, Haladhi
Bengali: Halud, Haldi
Gujarati : Haldar
Hindi: Haldi, Hardi
Kannad: Arishina
Malayam: Manjala
Marathi: Halad
Punjabi: Hardakh
Tamil: Manjal
Telugu: Pasupu
Urdu: Haldi.
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Habitat:[18]
Cultivated all over India, particularly in West Bengal, Tamil Nadu and
Maharashtra.
Geographical Source[19]
Haridra consists of the dried rhizomes of Curcuma longa Linn. (Fam. Zingiberaceae), a
perennial herb grows to a height of three to five feet extensively cultivated in all parts of the
country, crop is harvested after 9-10 months when lower leaves turn yellow rhizomes
carefully dug up with hand-picks between October-April and boiled, cleaned and dried,
yielding a yellow powder.
Description of the drug: The plant is perennial herb with short stem and tufted leaves.
Primary tubers are ellipsoidal and bear many rhizomes showing pattern of monopodial
growth. The leaves are acuminate, ascending and pubescent beneath, consists of cone shaped
collection of numerous ovate bracts and about 10-18 cm long and 5 cm broad. The flowers
are pale yellow borne in pairs in the axils. The seeds are black and shining with large,
lacerate and white aril. Flowering and fruiting take place in winter.[20]
Rhizomes are ovate, oblong or pyriform (round turmeric) or cylindrical, often short branched
(long turmeric), former about half as broad as long, latter 2-5 cm long and about 1-1.8 cm
thick, externally yellowish to yellowish-brown with root scars and annulations of leaf bases,
fracture horny, fractured surface orange to reddish brown, central cylinder twice as broad as
cortex: odour and taste characteristic.[21]
Chemical Constituents
Turmeric is an excellent source of both iron and manganese. It is also a good source of
vitamin B6, dietary fiber, and potassium.[22]
The primary active constituent of turmeric and
the one responsible for its vibrant yellow color is curcumin. Curcumin is the most well
studied constituent. The main constituents groups are polyphenolic curcuminoids which
include: curcumin (diferuloylmethan), demethoxycurcumin, bisdemethoxycurcumin, and
cyclocurcumin.[23]
Turmeric also contains: sesquiterpenes (turmerone, atlantone, zingiberone,
turmeronol, germacrone, and bisabolene), carbohydrates, protein, resins and caffeic acid.[24]
Parts Used: The rhizome, leaves and flowers are used medicinal purpose.
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Common adulteration[20]
Turmeric powder is sometimes adulterated with yellow earth, rice or maize starch, sand, grit
and talc while the whole turmeric is policed with lead chromate or metanil yellow.
Dose[25]
1-3 gm of the drug in powder form
Properties: Screening the various classical texts, Rasa (taste), Virya (potency), Vipaka (post
digestion effect) and Guna (property) of Haridra are mentioned in the table 1.
Table 1: Properties of Haridra (Curcuma Longa Linn.)
Text
Rasa
(Taste)
Guna
(property)
Virya
(potency)
Vipaka
(post digestion effect) Doshaghnata
(pacification
of Dosha) Katu
(pungent)
Tikta
(bitter)
Ruksha
(dry)
Ushna
(hot)
Katu
(pungent)
A.S. [26]
+ + - - - KP
B.P. [27]
+ + + + + KP
D.N.[28]
- + + + + -
R.N.[29]
+ + - + + K
K.N.[30]
+ + + + + KP
A.S.- Ashtanga Sangraha, B.P – Bhavaprakasha nighantu; D.N – Dhanwantari nighantu; R.N
– Raja Nighantu; K.N – Kaiyadeva nighantu; K-Kaphadosha, P- Pittadosha
Medicinal applications:[31]
Anemia, atherosclerosis, diabetes, oedema, haemorrhoids,
hepatitis, hysteria, indigestion, inflammation, skin disease, urinary disease, wound and bruise
healing, psoriasis, anorexia, cough, liver disorders, rheumatism, sinusitis.
Various formulations of Haridra in the Management of Panduroga
Table 2: Formulations of Haridra
Sr. no. Name of formulation Ingredients Reference Anupana
(Vehicle)
Few Churna (Powder) preparation of Haridra
1 Ajasakrutadi churna Aja Sakruta, Bid lavana,
Haridra, Saindhava S.S.U. 44/25;292 Honey
2 Haridra, Triphala Yoga Triphala, Haridra S.S. U. 44/19; 291 Ghee, Honey
3 Murvadi Yoga Murva, Haridra, Amalaki,
bhavna by Gomutra S.S.U. 44/28; 292 Honey
Few Kshara (alkali) preparation of Haridra
1. Ksharamruta
Kshara of Musta, Palasha,
Arjuna, Dhava, Apamarga,
Dhatura, Haridra, Vasa, Tila
H.S. 3rd
Sthana,
4/16-17; 230
Not
mentioned
Few Ghrita–Taila (Medicated Ghee and Oil) preparation of Haridra
1 Bruhtayadi Ghrita Bruhati, Kantakari, Haridra, S.S. U. 44/22 p. 291 Kshira (Milk)
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Kakamachi, Bimbi, Alambusha,
ghee,
2 Panchatikta Ghrita Guggulu
Nimba, Patola, Vasa, Guduchi,
Kantakari, Su. Guggulu, Ghee,
Pippali, Haridra, Devdaru,
Triphala Manjistha
B.R. 54/233-236;
632
Not
mentioned
3 Bruhat Panchagavya Ghrita
Dwi Panchamula, Triphala,
Haridra, Daruharidra, Vacha,
Saptaparna, Nilini, Katurohini,
Trivrita, Chitraka
C.K. 21/17-22; 180 Not
mentioned
4 Katukadhya Ghrita
Katuki, Rohini, Musta, Haridra,
Daruharidra, Vatsaka, Patola,
Chandana, Nimba,Bhunimba
Devdaru
C.S.Chi. 16/47-49;95
95, (Vol. IV)
Not
mentioned
5 Mahabhallataka Guda
Nimba, Bhallataka, Shariva,
Katuki, Triphala, Trikatu,
Haridra, Vacha, Khadira,
Patola, Vatsaka, Vidanga,
Vasa, bhunimba,
B.R. 54/207-221 Kshira (Milk)
6 Murvadya Ghrita
Murva, Katuki, Haridra, Vasa,
Pippali, Chandana, Parpata,
Patola,Trayamana, Bhunimba,
Kshira, Ghee
B.R. 12/136-137;
276
Not
mentioned
7 Tiktaka Ghrita
Triphala, Haridra,
Daruharidra, vasa, Parpata,
Patola, Katuki, Nimba,Pippali,
Chandana, Indrayava
B.R. 54/239-242;
633
Not
mentioned
8 Vyoshadhya Ghrita
(Mrudbhakhanaja Pandu)
Trikatu, Bilva, Haridra, Musta,
Daruharidra, Triphala, Patha,
Punarnava, DevdaruLauha
Bhasma
C.S.Chi. 16/119-20;
111 (Vol IV)
Not
mentioned
Few Leha (linctus) preparation of Haridra
1 Rajanyadi Leha
Haridra, Daruharidra, Bruhati,
Shaliparni, prishniparni,
Shatahva
C.K.64/22, Balaroga;
523 Honey, Ghee
2 Khadiravaleha
Khadira Kwatha, Vidanga,
Dhanyaka, Bala, Katuki, Sita,
yashtimadhu, Triphala,
Haridra, Daruharidra
Bangasena 44/127-
128; 548 Honey, Ghee
Few Guggulu /Modaka/ Vati (Pills) preparation of Haridra
1 Punarnava Mandura
Punarnava, Trivrita, Trikatu,
Vidanga, Daruharidra,
Chitraka, Kushtha, Haridra,
Daruharidra, Danti, Chavya,
Musta, Pippali,
Pippalimula,Suddha madura,
Gomutra
C.S.Chi. 16/93-96;
105,06
Takra
(Buttermilk)
2 Trikutadi Vati
Trikuta (Trikatu), Triphala,
Haridra, Nilini fruit, Musta,
manjistha, Katurohini,
Bangasena, 42/54-
57; 542
Tandulambu
(rice water)
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Shatavari, Shigrubija,
Gajapippali,
Shaliparni,Bhallataka, Danti
3 Chandraprabha Gutika
Karpura, Vacha, Musta,
Haridra, Ativisha, Trivrita
Danti, Twaka, Ela, Chitraka,
Guggulu, Shilajatu
B.R. 37/102-110;
514
Not
mentioned
Few Asava- Arishta (fermented liquor) preparation of Haridra
1 Gaudarishta
Manjistha, Haridra, Draksha,
Balamula, Lauha
Bhasma,Lodhra
C.S. Chi. 16/105;108
(Vol. IV)
Not
mentioned
2 Moolasava
Haridra, Dashamula,
Shatavari, Rushabhaka, Jivaka,
Musta, Manjistha, Vidanga,
Madhuka, Lodhra
C.S. Chi. 15/156-159 Not
mentioned
3 Pippalyasava
Pippali, Maricha, Chavya,
Haridra, Chitraka, Vidanga,
Lodhra, Patha, Dhatri, Ushira,
Chandana, Lavanga, Ela,
Twaka, Jatamansi
Sha.S., Madhyama
Khanda 10/28-33
Not
mentioned
4 Kumaryasava
Kumari, Lavanga, Chaturjata,
Chitraka, Haridra,
Daruharidra, Pippalimula,
Vidanga, Gajapippali, Chavika,
Kramuka, katurohini,Musta,
Triphala, Danti, kapikachhu
Sha.S. Madhyama
khanda 10/19-27;
236
Not
mentioned
5 Dashamularishta
Dashamula, Chitraka,
Pushkaramula, Guduchi,
Lodhra, Dhatri, Manjistha,
Devdaru, Pathya, Vidanga,
Jatamansi, Haridra,
Nagkeshara, Musta, Indrayava
Sha.S. Madhyama
Khanda, 10/78- 92;
239
Not
mentioned
Kharaliya Rasayoga (Herbomineral preparation) of Haridra
1 Nisha Lauha Lauha churna, Haridra,
Triphala, daruharidra, Katuki B. R. 12/29; 270 Honey, Ghee
2 Dhatri Lauha Amalaki, Haridra, Trikatu,
Suddha Lauha B.R. 12/30, 270 Honey, Ghee
3 Panchamrita Lauha Mandura
Lauha, Tamra Bhasma, Kajjali,
Trikatu, Triphala, Musta,
Vidanga, Chitraka, Haridra,
Daruharidra, Shati, Chavya,
Yamani, Jirakadwaya
B. R. 12/52-58; 271 Honey
4 Pandupanchanana Rasa
Lauha, Tamra Bhasma, Danti,
Chavika, Trivrita, Kutaja,
Katuki, Haridra, Suddha
Mandura
B.R. 12/99-102; 274 Ushna Jala
(hot water)
5 Punarnava Mandura
Punarnava, Trivrita, Trikatu,
Vidanga, Haridra, Musta,
Pippali, Madura, Gomutra
C.S. Chi. 16/93-96;
105-106
Takra
(buttermilk)
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C.S.[4]
- Charaka Samhita, S.S.[10]
- Sushruta Samhita, B.R.[32]
- Bhaishajya Ratnavali,
K.S.[33]
- Kashyap Samhita, H.S.[34]
- Harita Samhita, C. K.[35]
- Chakradatta, Sha.S.[36]
-
Sharngadhara Samhita, Chi.- Chikitsa sthana, U.- Uttaratantra
PROBABLE MODE OF ACTION OF TURMERIC (CURCUMA LONGA) IN
PANDUROGA
Katu Rasa (pungent) can promote Agni (digestive and metabolic fire) by their Dipana
(appetizer), & Pachana (digestive) properties which can nullify the Agnimandhya (weakened
digestive fire), Aruchi (anorexia) like symptoms of Pandu roga. Further, Katu Rasa has been
said as margan vivrunoti [37]
(penetrates obstruction in channels) and reach even minutes
level and increase micro circulation of the Rasa all over the body. By virtue of Dipana,
Pachana property it increases the Jatharagni (digestive and metabolic fire) and Dhatvagni
(tissue metabolism) and thus may helpful to break the pathogenesis of Panduroga. Ruksha
(dry) property of Haridra can revert back the conditions like Dhatu Shaithilya (flabbiness in
tissues) found in Panduroga.
Owing to its hepatoprotective effect,[38]
maintains normal function of Yakrita (Liver) to
convert Rasa into Rakta and thus produce excellent quality of Rakta Dhatu (blood). By virtue
of Appetizer, Digestive, Hepatoprotective, Cholagogue activity of Haridra, it improves
digestion and metabolism, ultimately absorption of nutrition. As curcuma longa is proved as
antioxidant,[39]
it has been found to be a very good immune enhancer. It improves general
health, immunity, vigor and luster of the skin etc. in patients having anemia. Moreover, Iron
deficiency anemia can be overcome through turmeric rich in iron which are essential
components in the formation of red blood cells.[40]
Role of Liver dysfunction in the development of Anemia
Liver performs vital roles in maintaining homeostasis and health. Liver is the major storage
site for iron, Vit B12 and folic acid. The liver is involved in or is responsible for various
hematological abnormalities due to its unique portal circulation and its synthetic (clotting
factors, thrombopoietin) and immune functions. Primary liver problems like cirrhosis can
lead to hematological abnormalities and primary hematological diseases can in turn affect the
liver and its functioning. Abnormalities in hematological indices are frequently encountered
in cirrhosis.[41]
Moreover, The liver plays an important role in the digestion and processing of
food. A person with a damaged liver may have impaired bile production and flow. When this
happens, the body may not be able to properly absorb nutrients. The frequent association of
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anemia with chronic liver disease and/or hepatocellular failure provides a rationale for
examining the role of the liver in the formation and destruction of red blood cells. Indeed, a
variety of different mechanisms may be implicated in the development of anemia in patients
with liver disease.[42]
In Ayurvedic texts Yakrita (Liver) has given more importance in connection with metabolic
functions. Yakrita (Liver) is said to be the seat of Pitta. All the functions of Pitta, especially
Ranjaka Pitta are attributed to liver. Again liver and spleen are considered as, the root of
Raktavahasrotas. So, liver is very much important in all diseases concerned with Raktavaha
Srotas.
Alcohol and Anemia[42]
Drinking of alcohol is said to be one of the cause of Panduroga by Acharya Sushruta.
Alcohol is toxic to the liver. Drinking alcohol in excess can give rise to acute alcoholic
hepatitis, fatty liver, alcoholic intoxication and cirrhosis of the liver. It is difficult to
overcome addiction to alcohol as in several cases. Alcohol is implicated in the pathogenesis
of chronic liver disease; it may contribute to anemia secondary to its direct effects on the liver
and also to other diverse mechanisms. Folic acid and vitamin B12 deficiencies develop
frequently in patients with cirrhosis. These deficiencies may be related to inadequate food
intake or intestinal malabsorption. Anemia in an alcoholic may also arise as a consequence of
the direct toxic effects of alcohol on erythrocyte precursors in the bone marrow.
Hepatoprotective activity of Curcuma Longa Linn.
Curcumin, the most common antioxidant constituent of Curcuma longa rhizome extract, was
reported to enhance apoptosis of damaged hepatocytes which might be the protective
mechanism whereby curcumin down-regulated inflammatory effects and fibrogenesis of the
liver. The ethanolic extract of Curcuma Longa rhizomes showed a significant
hepatoprotective effect when orally administrated in doses of 250 mg/kg and 500 mg/kg, and
the protective effect was dose dependent.[43]
Thus, by counter acting the liver pathology,
anemia is corrected by curcuma longa.
Role of Inflammation in the development of Anemia and Anti-inflammatory activity of
Curcuma Longa
Anemia of inflammation (AI) has historically been termed the “anemia of chronic disease”
and is most commonly observed in association with infection, rheumatologic disorders,
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malignancy, and other chronic illnesses. It seems more likely that the oxidative stress that
accompanies the evolution of our life is the real cause of the chronic inflammatory conditions
and that the same oxidative stress is actually a major cause of this anemia. The results of
preclinical and clinical studies, researchers have suggested the following main mechanisms
by which inflammation may affect anemia. Just as important seems to be the direct role of
inflammatory mediators in interfering with erythropoiesis by suppressing the bone marrow.
In fact, patients with chronic inflammatory diseases have been demonstrated to have
decreased red cell survival, disorders of erythropoiesis, EPO levels low for the degree of
anemia.[44]
Curcumin is the phytochemical derived from the rhizome of Curcuma longa. Curcuma longa
(turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory
conditions.[45]
The role of curcumin is supported by a number of scientific papers that have
confirmed its anti-inflammatory actions both in vitro and in vivo. [23],[46],[47]
Data of Clinical studies done on Haridra in Panduroga
1. Study Design: Kumawat N et al[48]
studied and given Nisha lauha (Haritaki, Amalaki,
Bibhitaki, Haridra, Kutki, Daruharidra in equal ratio and Lauha Bhasma in six ratio) in a
dose 500 mg twice daily and Phalatrikadi kwath (Haritaki, Amalaki, Bhibhitaki, Kutki,
Gudichi,Vasa, Nimbha, Bhunimba) in a dose 40 ml twice daily orally before taking meal with
Anupana (vehicle) of Madhu. Ferrous Sulphate was given in a dose of 200 mg thrice a day
orally after taking meal with water. Duration of trial was for 60 days.
Result: Highly significant improvement was observed in hemoglobin level after sixty days
treatment in both groups A and B. The intergroup comparison showed equal results in both
the groups which are statistically insignificant. In case of ESR, PCV, MCH, MCHC, TRBC,
S. Iron, TIBC in both groups statistically highly significant results observed in both the
groups (<0.001).
2. Study Design: In this study[49]
Virechana (with Trivrita powder) was given followed by
Shamana treatment Tab. Nisha Loha (250mg) twice a day with Anupana of Honey for 45
days in group A. While in group B Tab. Nisha Loha was given without doing Virechana.
Result: Study done by James Chacko showed 48% of moderate improvement, 32% patients
were assessed under improvement by Shamana group i.e. Nisha Loha. Only 12% showed
marked improvement. 8% were under unchanged category, whereas nobody included under
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complete relief. Moreover, Nisha Loha provided highly significant relief (p<0.001) in the
management of Panduta and Arohana ayasa by 48% and 44% respectively. Study revealed
that Hb% was significantly increased by 48% by Nisha Lauha.
3. Study Design:[50]
30 children having IDA were given Dhatri Loha compound (Amalaki,
Lohabhasma, Haridra, Trikatu, Amalakikashaya as per need for bhavana (lavigation))
(250 mg) twice a day for period of 2 months.
Result: Study done by Ragamala KC et al revealed that Dhatri Lauha provided statistically
highly significant change (P = <0.001) resulted in the signs and symptoms of IDA. There was
a statistically highly significant response in hemoglobin concentration in the group (P
=<0.001).
CONCLUSION
It can be concluded that the Haridra (Turmeric) has a lot of potentials in the treatment of
Anemia owing to its multiple pharmacological activities such as haematinic, digestive,
appetizer, antioxidant, Hepatoprotective, anti-inflammatory.
Experimental data suggests that curcumin acts as antioxidant and hepatoprotective which
may beneficial in treating patients of anemia with compromised liver and decreased
immunity. Various clinical research works have also proved the role of Haridra in Pandu
(anemia). Thus, it can be concluded that, Haridra may play an important role in the treatment
of Anemia.
REFERENCES
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