GENETIC MAPPING By Juana Hoyos Palacio Medicine Student

Introduction

The technique shows the position of

genes in the genome.

Inquire aobut the information that they have

Pituitary tumor transforming gene as a novel regulatory

factor of liver fibrosisLife sciences.

(2015, april 15).

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis

Scientists found by an exhaustive investigation that

the pituitary tumor transforming gene (PTTG) has an important function in liver

diseases.

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis

They used mice and mapping genes technique to find them in their loci. After that, they searched for a real correlation between both genes.

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis

Results showed that the mice with knockout PTTG

might prevent the development of liver

fibrosis

Liver fibrosis

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis

Student criterion This investigation is interesting because it shows the relationship between a gene that has the correlation with the brain and liver diseases.

From now on scientist have more tools to continue investigating genes, and other

implications they may have

This is helps demonstrate that almost every component in the body is correlated, and that patients need to be evaluated as a

whole

Molecular mapping of leaf rust

resistance genes in the wheat line Yu

356-9

Molecular mapping of leaf rust resistance genes in the wheat line Yu 356-9

The answer resides in the genetic information that each organism has. Some researchers from china had curiosity about the special resistance that has the wheat line 356-9 to leaf rust pathotypes

Have you ever wondered why some plants are more resistant to pathogens than others?

Molecular mapping of leaf rust resistance genes in the wheat line Yu 356-9

Scientists exposed several genes from a type of wheat to leaf rust pathotypes. All of them except Yu 356-9 were infected.

Molecular mapping of leaf rust resistance genes in the wheat line Yu 356-9

They used mapping genes strategy to find the place where the gene was.

Later they tried to determine if there were any relationship between the gene and the

neighbors’ gene.

The purpose was to know more about it and learn from it.

Molecular mapping of leaf rust resistance genes in the wheat line Yu 356-9

Student criterion

This is useful because with the modifications that the gene has, we can eat more healthy food. In this way we prevent the inducing of apoptosis becoming from the

food with nonresistance genes to pathogens.

Medical utility

Medical utility 

As well, molecular mapping can be used

to check the predisposition

people has about specific genes that develop diseases. 

Medical utilityThe technique is also

used in genetic therapy with crops to find any

weakness that their DNA might have and

"correct" the mistake; resulting in genetic

resistance. 

Medical utilityIn high-risk pregnancy, it allows to check the

genetic material of the fetus; giving

information to the doctors about the baby´s condition and what possible treatment to follow if necessary. 

Bibliografia • HAN Lui-sha, LI Zai-feng (2015), “ Molecular mapping

of leaf rust resistance genes in the wheat line Yu 356-9”, Journal of integrative agriculture, China. From: http://www.sciencedirect.com/science/article/pii/S2095311914609643

• Vyacheslav Buko, Belonovskaya Elena (2015), “pituitaty tumor transforming gene as a novel regulatory factor of lives fibrosis”, life sciences, Poland. From: http://www.sciencedirect.com/science/article/pii/S0024320515002301

• Martinez Sanches, Lina Maria. Biologia molecular, 8 , edicion, Medellin UPB . Fac.Medicina.

I LOVE BOB