friday december 7, 2007sbi3u | a. manaktola blood
TRANSCRIPT
Friday December 7, 2007 SBI3U | A. Manaktola
What is Blood?• Blood is the fluid that carries
nutrients, gases, hormones and wastes around the body
• Blood consists of:– plasma (the liquid part) 55% of volume– cellular components 45% of volume
(red blood cells, white blood cells, platelets)
• Average adult human has 5 to 6 L of blood (about 8% of body mass)
Friday December 7, 2007 SBI3U | A. Manaktola
Blood Composition
Plasma is a straw-colored liquid that contains dissolved proteins, salts, minerals, and hormones
Friday December 7, 2007 SBI3U | A. Manaktola
Cellular Components of Blood
POINT OF COMPARISON
RED BLOOD CELL
WHITE BLOOD CELL
PLATELETSLEUCOCYTES LYMPHOCYTES
ORIGINRed bone marrow
Red bond marrow
Spleen, lymph glands
Red bone marrow, lungs
CELLS/mm3 OF BLOOD
4.5 - 5.5 million 6000 2000 250 000
RELATIVE SIZE
Small (8 μm diameter)
Largest (up to 25 μm)
Large (10 μm) Smallest (2 μm)
FUNCTION
To carry oxygen and carbon dioxide to and from cells
To engulf foreign particles
To play a role in the formation of antibodies
To play a role in the clotting of blood
LIFE SPAN 120 daysA few hours to a few days
Unknown 7-8 days
Friday December 7, 2007 SBI3U | A. Manaktola
Blood Groups• There are four different kinds of
blood types: A, B, AB, or O
Friday December 7, 2007 SBI3U | A. Manaktola
Blood Groups
BLOOD GROUP
ANTIGENS PRESENT ON SURFACE OF
RBC
ANTIBODIES PRESENT IN
BLOOD PLASMA
A A B
B B A
AB A and B Neither A nor B
O Neither A nor B A and B
Friday December 7, 2007 SBI3U | A. Manaktola
RH Factor• Many people also have an Rh factor on the
RBC’s surface. This is also an antigen. • If Rh antigen is present, you are typed Rh+• A person with Rh- blood, does not have Rh
antibodies in their blood plasma. BUT, a person with Rh- blood can DEVELOP Rh antibodies if he/she receives blood from an Rh+ person.
• A person with Rh+ has no problem receiving blood from an Rh- person
Friday December 7, 2007 SBI3U | A. Manaktola
Agglutination• The A antigen and the A antibodies
can bind to each other in the same way that the B antigens can bind to the B antibodies.
• This is what would happen if, for instance, a B blood person receives blood from an A blood person.
Friday December 7, 2007 SBI3U | A. Manaktola
You are a surgical intern at Seattle Grace Hospital working long hours in the ER. Consider the following cases…
Friday December 7, 2007 SBI3U | A. Manaktola
Blood Groups• Which blood group would be
considered a “Universal Donor”?
• Which blood group would be considered a “Universal Recipient”?
Friday December 7, 2007 SBI3U | A. Manaktola
Debate TopicCan you fix a broken heart?
• Embryonic stem cell research is a controversial topic. – While some people believe that research should go
on in this field in order to develop cures for many diseases, others believe that it is not ethical to kill embryos – even if it is to save the lives of others.
http://news.bbc.co.uk/2/hi/health/3529765.stmhttp://stemcells.nih.gov/info/scireport/
chapter9.asp