www.espghan.org

PROGRAMME

European Society for Paediatric Gastroenterology, Hepatology and Nutrition

ESPGHAN MASTER CLASS ON GASTROINTESTINAL IMMUNOLOGY

NOVEMBER 16–18, 2017LEIDEN, THE NETHERLANDS

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EDUCATIONAL PARTNER PROGRAMME

ESPGHAN provides a variety of educational activities, events and information that are available thought out the year. The ESPGHAN Education Partner Programme (EPP) was launched in 2015. Based on the 2015 adopted ESPGHAN Code of Conduct, the EPP has been developed to ensure the on-going development and implementation of an up-to-date, independent, high quality educational programme for health care professionals. The dedicated support and financial commitment from our partners helps to enhance and stabilize support for ESPGHAN’s educational activities. The EPP educational activities for 2017 are:

Event Name Date Location

ESPGHAN Paediatric Nutrition: Beyond the Nutrients - Summer School June 25-30, 2017 Bari, Italy

ESPGHAN Danube/Balkan Summer School August 28-31, 2017 Murighiol, Romania

ESPGHAN AHP Summer School September 14-17,2017 Trakošćan, Croatia

ESPGHAN Young Investigator Forum September 20-23, 2017 Bergen, The Netherlands

ESPGHAN Paediatric GI Motility Hands-On Training Course September 26-27, 2017 London, United Kingdom

ESPGHAN GI School October 11-14, 2017 Cologne, Germany

ESPGHAN Master Class on Gastrointestinal Immunology November 16-18, 2017 Leiden, The Netherlands

ESPGHAN 3rd Paediatric IBD Masterclass November 23-25, 2017 Tel Aviv, Israel

ESPGHAN Monothematic Conference: Management of Progressive Liver Diseases February 01-03, 2018 Brussels, Belgium

We sincerely thank the following EPP partners for their generous support and commitment:

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ESPGHAN MASTER CLASS ON GASTROINTESTINAL IMMUNOLOGY

November 16–18, 2017 Leiden, The Netherlands

Organising Committee / Faculty

Organising Committee

Luisa Mearin Leiden University Medical Center Leiden – The Netherlands

Hankje Escher Erasmus Medical Center Rotterdam – The Netherlands

Carmen Ribes-Koninckx La Fe Children s Hospital Valencia – Spain

Faculty

Raanan Shamir Schneider Children’s Medical Center Petah Tikva – Israel

Gerd Bouma Free University Medical Center (VUmc) Amsterdam – The Netherlands

Robbert Bredius Leiden University Medical Center Leiden – The Netherlands

Glenn Furuta Children’s Hospital Colorado Colorado – USA

Antonio Garrote Hospital Universitario Rio Hortega Valladolid – Spain

Bana Jabri The University of Chicago Chicago – USA

Frits Koning Leiden University Medical Center Leiden – The Netherlands

Nicolette Moes University Medical Center Antwerp (UZA) Antwerp – Belgium

Michal Mokry Utrecht Medical Center Utrecht – The Netherlands

Edward Nieuwenhuis Utrecht Medical Center Utrecht – The Netherlands

Lissy de Ridder Erasmus Medical Center Rotterdam – The Netherlands

Edmond Rings Leiden University Medical Center Leiden – The Netherlands

Janneke Samsom Erasmus Medical Center Rotterdam – The Netherlands

Joachim Schweizer Leiden University Medical Center Leiden – The Netherlands

Ludvig Sollid University of Oslo Oslo – Norway

Riccardo Troncone University Federico II Naples – Italy

Astrid van Krevelen - van Halteren Leiden University Medical Center Leiden – The Netherlands

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For further information on the programme and registration please visit

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ABOUT ESPGHAN

WHO WE AREWe are a multi-professional organisation dedicated to the promotion of the health of children with special regard to the gastrointestinal tract, the liver and nutritional status. Our members include clinicians, scientists, trainees, and allied health professionals.

WHAT WE DO• Provide representation for professionals involved

in paediatric gastroenterology, hepatology and nutrition• Promote basic, translational and clinical science• Lobby for stronger support of research• Offer the highest standards of education

to our members and other involved professionals• Focus attention on new investigators and trainees

to ensure they are supported and encouraged• Serve as a source of competent advice for governments,

international agencies, and relevant stakeholders

HOW WE DO ITWe achieve the above by knowledge creation, the dissemination of science based information, the promotion of best practice in the delivery of care, and the provision of high quality education for paediatric gastroenterology, hepatology and nutrition professionals in Europe and beyond.

HOW TO JOIN USFor information on different membership types and application procedure please visit our website www.espghan.org/home/join.us or contact the ESPGHAN Office via office@espghan.org.

www.espghan.org

European Society for Paediatric Gastroenterology, Hepatology and Nutrition

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Venue: Hampshire Hotel, Fitland Leiden Bargelaan 180 2333 CW Leiden The Netherlands

DAY 1: THURSDAY, November 16, 2017

16.00 – 16.45 Arrival and Registration (Hampshire Hotel, Fitland Leiden)

16.45 – 17.00 Welcome - Raanan Shamir, ESGPHAN President

17.00 – 17.15 Welcome and Overview, Organising Committee (Hankje Escher, Luisa Mearin, Carmen Ribes)

Session 1: The Gastrointestinal (GI) System: Function and Immunology

Chair: Hankje Escher

17.15 – 17.30 Quiz (Edward Nieuwenhuis)

17.30 – 17.55 The GI function in Health and Disease (Edmond Rings)

17.55 – 18.20 The GI Immune Cells and Tissues (Janneke Samsom)

18.20 – 18.45 Cytokines & Lymphokines (Antonio Garrote)

19.00 Dinner at Hampshire Hotel Leiden

DAY 2: FRIDAY, November 17, 2017

Session 2: The Basics and the Clinic 1

Chair: Carmen Ribes

08.30 – 08.55 The Innate GI Immune Response (Bana Jabri)

08.55 – 09.20 The Adaptative GI Immune Response (Ludvig Sollid)

09.20 – 09.45 The role of the epithelium in the immune response (Edward Nieuwenhuis)

09.45 – 10.15 Coffee break

Session 3: The Basics and The Clinic 2

Chair: Edward Nieuwenhuis

10.15 – 10.40 The Immunology of IBD (Gerd Bouma)

10.40 – 11.05 The Immunology of Coeliac Disease (Frits Koning)

11.05 – 11.30 2 Cases Coeliac Disease (moderator Luisa Mearin) Coeliac Disease: A Case Report (Raanan Shamir) A Tricky Case: Coeliac or Not? (Roberta Mandile)

11.30 – 11.55 Genetic aspects of GI Immunology (Michal Mokry)

11.55 – 12.30 2 Cases IBD (moderator Hankje Escher) SCT in Refractory Crohn’s Disease (Nóra Judit Béres) IL-2Rbeta mutation in VEO-IBD (Edwin de Zoeten)

12.30 – 13.30 Lunch

Programme

ESPGHAN MASTER CLASS ON GASTROINTESTINAL IMMUNOLOGY

November 16–18, 2017 Leiden, The Netherlands

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For further information on the programme and registration please visit

Programme

ESPGHAN MASTER CLASS ON GASTROINTESTINAL IMMUNOLOGYNovember 16–18, 2017 Leiden, The Netherlands

Session 4: The Basics and The Clinic 3

Chair: Frits Koning

13.30 – 13.55 Oral Immunization and Tolerance (Riccardo Troncone)

13.55 – 14.20 2 Cases Food Allergy/Eosinophilic Diseases (moderator Edward Nieuwenhuis) Eosinophilic Gastroenteritis (Andy Darma) Eosinophilic Duodenitis (Catalina Ortiz)

14.20 – 15.30 Carroussel with interactive presentation of cases (Joachim Schweizer, Astrid van Krevelen - van Halteren, Robbert Bredius, Nicolette Moes, Janneke Samsom, Hankje Escher)

Group A

14.20 – 14.40 Station 1 case of Very Early Onset Inflammatory Bowel Disease (VEO-IBD)

14.45 – 15.05 Station 2 case of Gastrointestinal Graft versus host Disease (GvHD)

15.10 – 15.30 Station 3 case of Autoimmune Enteropathy

Group B

14.20 – 14.40 Station 2 case of Gastrointestinal Graft versus host Disease (GvHD)

14.45 – 15.05 Station 3 case of Autoimmune Enteropathy

15.10 – 15.30 Station 1 case of Very Early Onset Inflammatory Bowel Disease (VEO-IBD)

Group C

14.20 – 14.40 Station 3 case of Autoimmune Enteropathy

14.45 – 15.05 Station 1 case of Very Early Onset Inflammatory Bowel Disease (VEO-IBD)

15.10 – 15.30 Station 2 case of Gastrointestinal Graft versus host Disease (GvHD)

15.30 – 16.00 Tea break

Session 5: Basics BREAK OUT to the lab

16.00 – 18.10 2 interactive stations rotation to laboratory with demonstration of lab immunology techniques. Station 1: Frits Koning and Lab Station 2: Janneke Samsom and Lab

19.00 – 20.30 Social Event - Leiden

20.30 Dinner at Faculty Club Leiden

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For further information on the programme and registration please visit

DAY 3: SATURDAY, November 18, 2017

Session 6: New and Future Developments 1

Chair: Janneke Samson

08.30 – 08.50 Immunosuppression and Immunomodulation in IBD (Lissy de Ridder)

08.50 – 09.15 Primary Immunodeficiencies (Robbert Bredius/Nicolette Moes)

09.15 – 10.05 The Immunology of Eosinophilic Gastrointestinal Diseases (Glenn Furuta)

10.05 – 10.30 New and Future In Coeliac Disease (Frits Koning)

10.30 – 11.00 Coffee break and Picture

Session 7: New and Future Developments 2

Chair: Luisa Mearin

11.00 – 11.25 New and Future In IBD (Janneke Samsom)

11.25 – 11.50 New and Future In Eosinophilic Gastrointestinal Diseases (Glenn Furuta)

11.50 – 12.05 Pitch your project 1: Histological Characteristics of IBD in Infants and Toddlers. (Elena Cernat)

12.05 – 12.20 Pitch your project 2: Prevalence of Autoimmune Diseases in Pediatric IBD. (Victoria Merrick)

12.20 – 12.35 Pitch your project 3: Antidepressants in Pregnancy and Intestinal Inflammation in Rats. (Katherine Prowse)

12.35 – 12.50 Pitch your project 4: Zebrafish Model Interaction Immunology and Microbiome in Obesity. (Alfonso Rodriguez Herrera)

12.50 – 13.05 Quiz (Edward Nieuwenhuis)

13.05 – 13.35 Summary and Closing Remarks (Luisa Mearin)

13.35 Lunch and departure

Programme

ESPGHAN MASTER CLASS ON GASTROINTESTINAL IMMUNOLOGY

November 16–18, 2017 Leiden, The Netherlands

ESPGHAN Master Class on Gastrointestinal Immunology (16-18 November, 2017) has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) to provide the following CME activity for medical specialists. ESPGHAN Master Class on Gastrointestinal Immunology 2017 is designated for a maximum of, or up to 12 European CME credits (ECMEC®s).

We sincerely thank the following EPP partners for their generous support and commitment:

Date of printing: November 2017 Design: www.biegl-grafik.atWhile the greatest care is taken in compiling this information, the editor does not take responsibility for any printing errors or omissions.

European Society for Paediatric Gastroenterology, Hepatology and Nutrition

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