Department of Biomedical Engineering           1

DEPARTMENT OF BIOMEDICALENGINEERINGhttp://engineering.tamu.edu/biomedical

Head: A. Guiseppi-Elie

Graduate Advisor: M. J. McShane

The thrust of the biomedical engineering graduate program is centeredaround a clinical and translational focus on patients and outcomesand spans five thematic areas:  medical diagnostics/theranostics,regeneration, telemedicine and health IT, augmentation, and precisionintervention.  Research themes are carried out in several disciplines,including biomedical sensing and imaging, biomedical optics,biomechanics, biomaterials, tissue engineering, and biomolecularand cellular engineering.  Faculty members are presently involvedin research from the macroscopic to the nanoscale in the areas ofdiagnostic and therapeutic systems, imaging systems, soft and hardtissue biomechanics, tissue characterization, biomaterials used inthe human body, orthopedic and injury biomechanics, FDA regulatorypractices, bioinstrumentation, measurement and analysis of human bodysignals, and analysis of the interaction between humans and medicaldevices.

FacultyAlge, Daniel L, Assistant ProfessorBiomedical EngineeringPHD, Purdue University, 2010

Applegate, Brian E, Associate ProfessorBiomedical EngineeringPHD, Ohio State University, 2000

Bishop, Corey J, Assistant ProfessorBiomedical EngineeringPHD, The Johns Hopkins University School of Medicine, 2015

Biswas, Saurabh, Associate Professor of the PracticeBiomedical EngineeringPHD, Texas A&M University, 2011

Bukkapatnam, Satish T, ProfessorBiomedical EngineeringPHD, Pennsylvania State University, 1997

Clubb Jr, Fred J, ProfessorBiomedical EngineeringPHD, University of Alabama - Birmingham, 1983DVM, Auburn University, 1971

Cosgriff-Hernandez, Elizabeth M, Associate ProfessorBiomedical EngineeringPHD, Case Western Reserve University, 2005

Cote, Gerard L, ProfessorBiomedical EngineeringPHD, University of Connecticut, 1990

Criscione, John C, ProfessorBiomedical EngineeringPHD, The John Hopkins University School of Medicine, 2005

Fink, Rainer J, Associate ProfessorBiomedical EngineeringPHD, Texas A&M University, 1995

Freed, Alan D, ProfessorBiomedical EngineeringDEN, University of Wisconsin - Madison, 1985

Gaharwar, Akhilesh K, Assistant ProfessorBiomedical EngineeringPHD, Purdue University, 2011

Gibbs, Holly C, LecturerBiomedical EngineeringPHD, Texas A&M University, 2015

Gonezen, Sevan, Assistant ProfessorBiomedical EngineeringPHD, Rensselaer Polytechnic Institute, 2011

Gregory, Carl A, Assistant ProfessorBiomedical EngineeringPHD, University of Manchester, 1999

Grunlan, Melissa A, ProfessorBiomedical EngineeringPHD, University of South Carolina, 2004

Guiseppi Elie, Anthony, ProfessorBiomedical EngineeringPHD, Massachusetts Institute of Technology, 1983

Han, Arum, ProfessorBiomedical EngineeringPHD, Georgia Institute of Technology, 2005

Hogan, Harry A, Associate ProfessorBiomedical EngineeringPHD, Texas A&M University, 1984

Huang, Shuning, LecturerBiomedical EngineeringPHD, Massachusetts Institute of Technology, 2009

Hwang, Wonmuk, Associate ProfessorBiomedical EngineeringPHD, Boston University, 2001

Jafari, Roozbeh, Associate ProfessorBiomedical EngineeringPHD, University of California, 2006

Jain, Abhishek, Assistant ProfessorBiomedical EngineeringPHD, Boston University, 2012

Jayaraman, Arul, ProfessorBiomedical EngineeringPHD, University of California, Irvine, 1998

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Jo, Javier A, Associate ProfessorBiomedical EngineeringPHD, University of Southern California, 2002

Kaunas, Roland R, Associate ProfessorBiomedical EngineeringPHD, University of California, San Diego, 2003

Keller, Brandis K, LecturerBiomedical EngineeringPHD, Politecnico di Milano, 2013

Lawley, Mark A, ProfessorBiomedical EngineeringPHD, University of Illinois at Urbana-Champaign, 1995

Maitland IV, Duncan J, ProfessorBiomedical EngineeringPHD, Northwestern University, 1995

Maitland, Kristen D, Associate ProfessorBiomedical EngineeringPHD, University of Texas, 2006

McDougall, Mary P, Associate ProfessorBiomedical EngineeringPHD, Texas A&M University, 2004

McShane II, Michael J, ProfessorBiomedical EngineeringPHD, Texas A&M University, 1999

Moreno, Michael R, Assistant ProfessorBiomedical EngineeringPHD, Texas A&M University, 2009

Ober, Raimund J, ProfessorBiomedical EngineeringPHD, Cambridge University, 1987

Peterson, Donald, ProfessorBiomedical EngineeringPHD, University of Connecticut, 1999

Quick, Christopher M, Associate ProfessorBiomedical EngineeringPHD, Rutgers University, 1999

Rajagopal, Kumbakonam, ProfessorBiomedical EngineeringPHD, University of Minnesota, 1978

Sears, Nicholas A, LecturerBiomedical EngineeringPHD, Texas A&M University, 2017

Stoica, Gheorghe, ProfessorBiomedical EngineeringPHD, Michigan State University, 1984DVM, Institute of Agronomy, Yassy, Romania, 1966

Trache, Andreea, Associate ProfessorBiomedical EngineeringPHD, Institute of Atomic Physics, Romania, 1996

Ugaz, Victor M, ProfessorBiomedical EngineeringPHD, Northwestern University, 1999

Wilson, Emily, ProfessorBiomedical EngineeringPHD, Emory University, 1987

Wright, Steven M, ProfessorBiomedical EngineeringPHD, University of Illinois, 1984

Yakovlev, Vladislav V, ProfessorBiomedical EngineeringPHD, Moscow State University, 1990

Yeh, Alvin T, Associate ProfessorBiomedical EngineeringPHD, University of California, Berkeley, 2000

Zawieja, David C, ProfessorBiomedical EngineeringPHD, The Medical College of Wisconsin, 1986

Masters• Master of Engineering in Biomedical Engineering (http://

catalog.tamu.edu/graduate/colleges-schools-interdisciplinary/engineering/biomedical/meng)

• Master of Science in Biomedical Engineering (http://catalog.tamu.edu/graduate/colleges-schools-interdisciplinary/engineering/biomedical/ms)

Doctoral• Doctor of Philosophy in Biomedical Engineering (http://

catalog.tamu.edu/graduate/colleges-schools-interdisciplinary/engineering/biomedical/phd)

Certificates• Quality Engineering for Regulated Medical Technologies Certificate

CoursesBMEN 604 FDA Good Laboratory and Clinical PracticesCredits 3. 3 Lecture Hours.Implementation of Good Laboratory Practices (GLP) for the submissionof preclinical studies and use of Good Clinical Practices (GCP) inclinical trials in accordance with Food and Drug Administration (FDA)regulations; includes similarities and differences in GLP and GCP criticalfor the introduction of new drugs and medical devices.Prerequisite: Graduate classification or approval of instructor.

BMEN 606 Medical Device Path to MarketCredits 3. 3 Lecture Hours.Path to market for a medical device with specific attention to theregulatory affairs to enable the development of an appropriate regulatorystrategy due to the highly regulated global environment.Prerequisite: Graduate classification or approval of instructor.

Department of Biomedical Engineering           3

BMEN 608 Biophotonics IICredits 3. 3 Lecture Hours.Photon transport in tissue; photon scattering and absorption; Miescattering; Monte Carlo; optical spectroscopy, including absorption,fluorescence, and Raman scattering; multiphoton processes; plasmonics.Prerequisite: BMEN 625 or approval of instructor.

BMEN 622 BioelectromagnetismCredits 3. 3 Lecture Hours.Electric, magnetic and electromagnetic phenomena in association withbiological tissues; source modeling based on physiological currentincluding line and volume conductor models as well as electromagnetic-based stimulation, sensing and imaging.Prerequisite: Graduate classification or approval of instructor.

BMEN 625 BiophotonicsCredits 3. 3 Lecture Hours.Theory and application of optical instrumentation, including light sources,lasers, detectors, and optical fibers; instrumentation and engineeringin biomedical applications of optics in therapeutics, diagnostics, andbiosensing.Prerequisite: Graduate classification or approval of instructor.

BMEN 627/ECEN 763 Magnetic Resonance EngineeringCredits 3. 2 Lecture Hours. 3 Lab Hours.Design, construction and application of instrumentation for MR imaging;fundamentals of the architecture of an MR spectrometer and the gradientsubsystem used for image localization; emphasis on the radiofrequencysensors and systems used for signal generation and reception.Prerequisites: BMEN major; graduate classification or approval ofinstructor.Cross Listing: ECEN 763/BMEN 627.

BMEN 628 Embedded Systems for Medical ApplicationsCredits 3. 2 Lecture Hours. 3 Lab Hours.Principles of embedded system architecture and programming;fundamentals and theoretical foundations of wireless communicationsystems; hands-on experiences of how an embedded system could beused to solve problems in biomedical engineering; projects on wirelesssensors and imaging for medical devices.Prerequisite: Graduate classification or approval of instructor.

BMEN 631 Biomolecular EngineeringCredits 3. 3 Lecture Hours.Foundations for understanding the experimental approaches formeasuring and manipulating biomolecules; proteins, nucleic acids, andcarbohydrates; thermodynamics and kinetics of biomolecular reactions.Prerequisite: Graduate classification or approval of instructor.

BMEN 632 Molecular and Cellular BiomechanicsCredits 3. 3 Lecture Hours.Introduces biomolecules and their assemblies that play structural anddynamical roles in subcellular to cellular level mechanics, with emphasison quantitative/theoretical descriptions, and discussions of the relevantexperiment approaches to probe these nano to micro-scale phenomena;including topics in (1) self-assembly of cytoskeleton and biomembranes,(2) molecular motors, (3) cell motility, and mechanotransduction.Prerequisites: Graduate classification or approval of instructor.

BMEN 635 Biomaterials CompatibilityCredits 3. 3 Lecture Hours.Relevance of mechanical and physical properties to implant selection anddesign; effect of the body environment on metallic, ceramic and plasticmaterials; tissue engineering; rejection mechanisms used by the body tomaintain homeostasis regulatory requirements.Prerequisites: Approval of instructor.

BMEN 636 Pathophysiology of Systemic Diseases Augmented withImplantable DevicesCredits 3. 3 Lecture Hours.Clinical presentation of patients with systemic diseases and thepathophysiologic interrelationship with therapeutic implantabledevices; processes of inflammation/repair as it applies to challengesof therapeutic augmentation with implantable devices; systemscovered include cardiovascular, central nervous system, eye, dental,gastrointestinal, musculoskeletal, endocrine, reproductive/urogenital,skin/soft tissue; implantable device intervention as a therapeutic adjunctin systemic diseases.Prerequisites: Graduate classification or approval of instructor.

BMEN 637 Pathological Basis of Implantable DevicesCredits 3. 3 Lecture Hours.Understanding the relationship that clinical presentation has forpatients with primary heart disease; inflammation and repair, systematicpathology emphasis on cardiovascular disease, and the implantabledevice intervention as a therapeutic adjunct in the heart.Prerequisite: Graduate classification or approval of instructor.

BMEN 641 Numerical Methods in Biomedical EngineeringCredits 3. 3 Lecture Hours.Application of numerical analysis to analyze molecular, cellular andphysiological systems; general techniques used to analyze steady anddynamic systems; techniques will be applied in a MATLAB programmingenvironment.Prerequisite: Graduate classification or approval of instructor.

BMEN 642 Mass and Energy Transfer in BiosystemsCredits 3. 3 Lecture Hours.Understanding the transport phenomena associated with physiologicalsystems and their interaction with medical devices; exchange processesin artificial life support systems and diagnostic equipment.Prerequisite: Graduate classification or approval of instructor.

BMEN 643 Risk Based Development and Testing of Medical DevicesCredits 3. 3 Lecture Hours.Focus on the detailed design and development phases of the designinnovation process for healthcare applications; includes medical devicedevelopment projects in which teams will work on innovative medicaldevices that progressed through the concept phase of the developmentlife cycle; includes detailed design and development, risk based designprocess, including the conduct of hazards analysis, design FMEA,application FMEA, process FMEA, device manufacturing, device testingand FDA design verification and validation.Prerequisites: Enrolled in master of engineering in biomedicalengineering; graduate classification or approval of instructor.

BMEN 650 Biomedical Optics LaboratoryCredits 3. 2 Lecture Hours. 3 Lab Hours.Biomedical optics technology; basic engineering principles used indeveloping therapeutic and diagnostic devices; a series of hands-on labswill be performed including optical monitoring, diagnostic and therapeuticexperiments.Prerequisite: Graduate classification or approval of instructor.

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BMEN 651 Cell MechanobiologyCredits 3. 3 Lecture Hours.Focuses on how mechanical forces influence cell behavior throughphysical and biochemical mechanisms; objectives include integratingengineering and cell biology to solve biomedical problems, whichincludes developing models for applying forces to cultured cells andtissues and measuring changes in cell biochemistry, structure, andfunction.Prerequisite: Graduate classification or approval of instructor.

BMEN 657 Orthopedic BiomechanicsCredits 3. 3 Lecture Hours.Fundamental course in orthopedic biomechanics designed to developcompetencies in biomechanical principles using practical examples andclinical case studies of how biomechanical knowledge is applied to theevaluation of musculoskeletal tissues and structures, and treatmentoptions for musculoskeletal dysfunction.Prerequisite(s): Admitted into the major degree sequence in BiomedicalEngineering and graduate classification.

BMEN 658 Motion BiomechanicsCredits 3. 3 Lecture Hours.Skeletal anatomy and mechanics; muscle anatomy and mechanics;theory and application of electromyography; motion and force measuringequipment and techniques; inverse dynamics modeling of the humanbody; current topics in musculoskeletal biomechanics research.Prerequisites: Graduate classification or approval of instructor.

BMEN 661 Cardiac MechanicsCredits 3. 3 Lecture Hours.Application of continuum mechanics and computational solid mechanicsto the study of the mammalian heart; utilization of continuum mechanicsand finite element analysis in solving non-linear boundary value problemsin biomechanics.Prerequisite: Graduate classification or approval of instructor.

BMEN 663 Soft Tissue Mechanics and Finite Element MethodsCredits 3. 3 Lecture Hours.Application of continuum mechanics and finite element methods tothe study of the mechanical behavior or soft tissues and associativeapplications in biomedicine.Prerequisite: Graduate classification or approval of instructor.

BMEN 669 Entrepreneurial Pathways in Medical DevicesCredits 3. 3 Lecture Hours.Overview of fundamental elements and development steps foran effective strategy pathway including regulatory pathway forcommercialization of medical product/medical device innovations;application of the basic regulations and associated requirements andenforcements for product market approval; exploration of product qualitytest method design requirements; understanding of the applicableregulations and standards pertaining to the design, testing, approval andmarketing of medical devices.Prerequisite: Graduate classification or approval of instructor.

BMEN 674 Communications in Biomedical EngineeringCredits 3. 3 Lecture Hours.General concepts for communicating the results of biomedical researchincluding written papers, conference proceedings, proposals and grants,as well as oral presentations and basic ethics.Prerequisite: Approval of instructor.

BMEN 675 Biomedical Case StudiesCredit 1. 1 Lecture Hour.Introduction to the engineering design process for solving biomedicalproblems by using the case study method in biomedical instrumentdesign.Prerequisite: Approval of instructor.

BMEN 676 Professional Development for Biomedical EngineeringCredits 3. 3 Lecture Hours.Advanced concepts in professional interactions including oral and writtencommunications; skills related to interviewing and obtaining job offersand understanding employment compensation and benefits; professionalethics.Prerequisite: Graduate classification or approval of instructor.

BMEN 680 Biomedical Engineering of TissuesCredits 3. 3 Lecture Hours.Introduction to engineering strategies used to repair tissue; literature-grounded overview of current strategies using stem cells, 3D scaffoldsand drug/gene delivery including ethical considerations of thesetherapies.Prerequisite: Graduate classification or approval of instructor.

BMEN 681 SeminarCredit 1. 1 Lecture Hour.Designed to permit student to broaden capability, performance andperspective in biomedical engineering via his or her own formalpresentation and by presentations from other professionals.Prerequisite: Approval of instructor.

BMEN 682 Polymeric BiomaterialsCredits 3. 3 Lecture Hours.Preparation, properties, and biomedical applications of polymersincluding polymerization; structure-property relationships; molecularweight and measurement; morphology; thermal transitions; networkformation; mechanical behavior; polymeric surface modification; polymerbiocompatibility and bioadhesion; polymers in medicine, dentistry,and surgery; polymers for drug delivery; polymeric hydrogels; andbiodegradable polymers.Prerequisites: Graduate classification or approval of instructor.

BMEN 683 Polymeric Biomaterial SynthesisCredits 3. 3 Lecture Hours.Overview of polymer synthetic routes and key structure-propertyrelationships with emphasis on the design of polymeric systemsto achieve specific properties; tissue engineering and drug deliveryapplications will be used as model systems to explore the process ofbiomaterial design from synthesis to device evaluation.Prerequisite: Graduate classification or approval of instructor.

BMEN 684 Professional InternshipCredits 1 to 12. 1 to 12 Other Hours.Training under the supervision of practicing engineers in settingsappropriate to the student's professional objectives.Prerequisites: Approval of chair of student's advisory committee anddepartment head.

BMEN 685 Directed StudiesCredits 1 to 12. 1 to 12 Other Hours.Allows students the opportunity to undertake and complete, for credit,limited investigations not included within thesis or dissertation researchand not covered by other courses. May be repeated for credit.Prerequisites: Approval of designated instructor and approved projectproposal.

Department of Biomedical Engineering           5

BMEN 686 Biomedical NanotechnologyCredits 3. 3 Lecture Hours.Introduction to nanotechnology applications in biomedicine; conceptsof scale; unique properties at the nanoscale; biological interaction,transport, and biocompatibility of nanomaterials; current research anddevelopment of nanotechnology for medical applications, includingsensors, diagnostic tools, drug delivery systems, therapeutic devices, andinteractions of cells and biomolecules with nanostructured surfaces.Prerequisite: Graduate classification or approval of instructor.

BMEN 687 Drug DeliveryCredits 3. 3 Lecture Hours.Mechanisms for controlled release of pharmaceutically active agentsand the development of useful drug delivery systems; controlled releasemechanisms including diffusive, convective and erosive driving forcesby using case studies related to oral, topical and parenteral release in afrontier interdisciplinary scientific research format.Prerequisite: Graduate classification in biomedical engineering orapproval of instructor.

BMEN 689 Special Topics in...Credits 1 to 4. 1 to 4 Lecture Hours. 0 to 4 Lab Hours.Selected topics in an identified area of biomedical engineering. May berepeated for credit.Prerequisite: Approval of instructor.

BMEN 691 ResearchCredits 1 to 23. 1 to 23 Other Hours.Research for thesis or dissertation.