cyclins and cell cycle regulation - abcam · 2009. 6. 8. · cyclins and cell cycle regulation cell...

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Cyclins and Cell Cycle Regulation Cell decides whether to continue Cell prepares to divide Cell division (mitosis) Cycle begins Cell grows Replication of DNA Cyclin E CDK2 Rb dephosphorylation Rb phosphorylation G2 M G1 S Cyclin B/A CDK1/ CDC2 Cyclin A CDK2 Cyclin D CDK4,6 Cdk2 antibody (ab7954) ATM (phospho S1981) antibody (ab2888) p21 antibody (ab18209) p57 Kip2 antibody (ab4058) Abcam in Japan Abcam K.K. 1-16-8 Nihonbashi Kak igaracho Chuo-ku,T okyo 103-0014 Japan T el: +81-(0)3-6231-0940 Fax: +81-(0)3-6231-0941 www.abcam.co.jp Abcam in Europe Abcam plc, 330 Cambridge Science Park Milton Road, Cambridge. CB4 0FL UK T el: +44 1223 696000 Fax: +44 1223 771600 Abcam in the USA Abcam Inc. 1 Kendall Square,Ste 341 Cambridge .MA 02139-1517 US A T el: 1-617-225-2272 T oll free: 1-888-77- ABCAM T oll free F ax: 1-866-739-9884 www.abcam.com Copyright © 2009 Abcam, All Rights Reserved.The Abcam logo is a registered trademark. All information/detail is correct at time of going to print.

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Page 1: Cyclins and Cell Cycle Regulation - Abcam · 2009. 6. 8. · Cyclins and Cell Cycle Regulation Cell decides whether to continue Cell prepares to divide Cell division (mitosis) Cycle

Cyclins and Cell Cycle Regulation

Cell decideswhether tocontinue

Cell preparesto divide

Cell division(mitosis)

Cycle begins

Cell grows

Replicationof DNA

Cyclin E

CDK2

Rb dephosphorylation

Rb

phosphorylation

G2

M

G1

S

Cyclin B/A

CDK1/ CDC2

Cyclin A

CDK2

Cyclin D

CDK4,6

Cdk2 antibody (ab7954) ATM (phospho S1981)

antibody (ab2888)

p21 antibody (ab18209) p57 Kip2 antibody (ab4058)

Abcam in JapanAbcam K.K.1-16-8 Nihonbashi KakigarachoChuo-ku, Tokyo 103-0014 Japan

Tel: +81-(0)3-6231-0940Fax: +81-(0)3-6231-0941

www.abcam.co.jp

Abcam in EuropeAbcam plc,330 Cambridge Science ParkMilton Road, Cambridge.CB4 0FL UK

Tel: +44 1223 696000Fax: +44 1223 771600

Abcam in the USAAbcam Inc.1 Kendall Square, Ste 341Cambridge. MA 02139-1517 USA

Tel: 1-617-225-2272Toll free: 1-888-77-ABCAMToll free Fax: 1-866-739-9884

www.abcam.com

Copyright © 2009 Abcam, All Rights Reserved. The Abcam logo is a registered trademark. All information/detail is correct at time of going to print.