ct dose excellence project: a pan european approach
TRANSCRIPT
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CT Dose Excellence Project: A Pan European approach towards protocols unification and dose optimization
ECMP September 2016 Katia Katsari
Affidea Chief Medical Physicist Dose Excellence Project Leader
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affideaconstant progress through ideas and innovation
affideaaffinity with doctors and patients
affideatrust and fidelity in everything we do
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Leading independent provider of Advanced Diagnostic Imaging and Cancer Care services in Europe
14 countries in Europe
3300 employees
680 medical doctors
170 medical centres
4.5m examinations
Dutch holding company, owned by Waypoint Capital, the leading Swiss investor in Life Sciences Europe’s biggest investor and consolidator on the Advanced Diagnostics and Cancer Care markets The largest, most experienced healthcare provider under the Public Private Partnership (PPP) model and an integral part of national healthcare systems
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145 MRI units
100 CT scanners
910 diagnostic and cancer care
modalities
22 linear accelerators
3 gamma knives
17 PET-CT
scanners
Best-in-class medical technology
* COCIR Data
* EU average affidea IB
< 6 Yrs 10 - 6 Yrs >10 Yrs
57% 47%
38% 34%
5% 19%
Affidea’s technology update investments, proprietary asset management system and large scale partnership with technology vendors result in the latest technology IB and youngest equipment fleet
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Clinical Governance Infrastructure § Affidea Medical Council comprising Country Medical Directors
in all 14 countries.
§ Medical Advisory Board Seven Leading European Radiology experts (four previous Presidents of ESR) providing international leadership.
§ Cancer Treatment Centre (CTC) Steering Committee in collaboration with Houston Methodists Group and independent Senior Clinician from Oxford University.
§ Nuclear Medicine Working Group specifically focusing on countries that provide nuclear medicine examinations such as PET CT.
Dr. Rowland Illing, Affidea CMO
Prof. Andras Palko, University of Szeged, Affidea MAB Chairman
Prof. Filipe Caseiro Alves, University of Coimbra, Affidea Medical Council Chairman
Prof. Ricky Sharma, Oxford University, Affidea Radiotherapy Consultant
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Radiation from Medical Imaging
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Facts for medical imaging
The per capita dose of radiation
from medical imaging
has increased by 600%
since the early 1980s
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Continuing expansion of CT practice
240202
193181179
173145
145142141
141134
132123
120110
9696
9290
7671
7162
595555
32
0 50 100 150 200 250
United StatesLuxembourg
FranceGreeceBelgiumIcelandKorea³Turkey
DenmarkIsrael
Portugal¹Austria¹
CanadaSlovak Rep.
OECD27Australia²
SpainCzech Rep.
HungarySwitzerland¹
United Kingdom¹Netherlands³
ChileGermany¹
Ireland¹Poland
SloveniaFinland
Per 1 000 population
Source:OECDHealthSta2s2cs2015:CTexams,2013ornearestyear
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Facts for CT examinations
In 1996 the contribution to the annual cumulative effective dose by CT examinations was 5%.
In 2009 the contribution to the annual cumulative effective dose by CT examinations is 46%.
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Diagnostic imaging radiation incidents
§ 23 January 2008 A licensed technologist, in Arcata, California performed 151 CT scan slices on a single 3 mm level on the head of a 23-month child over a 65-min period. This led to a dose of 5.4Gy to the brain and 1.5Gy to the lenses of both eyes!
§ February 2008 – August 2009 A software misconfiguration in a CT scanner used for brain perfusion scanning at Cedar Sinai Medical Center in Los Angeles, California, resulted in 206 patients receiving radiation doses approximately 8 times higher than intended.
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Legislation & Exposure from Medical Ionizing Radiation
COUNCIL DIRECTIVE 2013/59/EURATOM of 5 December 2013
Basic Safety Standards for Protection Against Dangers Arising from Exposure to Ionizing
Radiation
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Multi-slice CT scanners
Modern CT scanners are capable of providing precise detail of patient
anatomy, but…this is not always required
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appropriate image quality at optimized dose
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Poor Image Quality
…not too little
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Unnecessary Dose
…not too much
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perfect balance
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Dose ExcellenceB A L A N C E D R D I O G R A P H Y
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The process
Dose ExcellenceB A L A N C E D R D I O G R A P H Y
Standardized & Unified Protocols
with DRLs
Standard procedures
DoseWatch
Track & Record dose data and
more
Track & Justify high dose level
alerts Analyze data
Optimize protocols & DRL
Vision
Leadership
Teams
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Set clear goals
Create a culture of dose
awareness
Provide comprehensive education on
technology and effects of radiation
Define and set up an adapted high dose level
alert system
Justify alerts and minimize
through root – cause analysis
Create a standard list of
procedures based on
clinical indication
Prioritize optimization of
acquisition parameters
and practices
Analyse impact on dose leves
and image quality
Validate new
protocols, update DRLs,
implement best practice
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DEP Teams and Communication channels
GE DoseWatch
Steering Team Application Specialists
Centre Manager
Service Providers
Performance Optimization
Manager
HQ Project Leader
Chief Information
Officer
Sponsor
Chief Medical Officer
Corporate Marketing
Director
Chief Radiologist
Project Leader
IT
Marketing
Medical Physicist
Chief Radiographer
STEERING COMMITTEE
CEO
Chief Radiologist
Chief Radiographer
HQ Country Centre External Body
External Body
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CT protocols and DRLs
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Adult CT protocols categories
• By anatomic region and clinical indication. To further categorize by standard and big patients. Routine
• By anatomic region CTA
• By primary tumor type: lung, breast, upper abdomen, lower abdomen, lymphoma, sarcoma, melanoma, head & neck Oncology follow up
• Chest Screening
• By prospective, retrospective and BPM Cardiac
• Biopsy (liver, lung etc.), joint injection, drainage/therapy (abdominal cavity, liver, spine etc.) Interventional
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Pediatric CT protocols categories
• By anatomic region, clinical indication, weight or age Routine
• By primary tumor type: leukemia, brain/CNS, neuroblastoma, nephroblastoma, lymphoma, osteosarcoma Oncology follow up
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Example of adult unified protocols setup
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The number of unified protocols is important
69%
31%
29 Unified CT protocols
Exams performed with unified protocols Other protocols 87%
13%
75 Unified CT protocols
Exams performed with unified protocols
Other protocols
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Dose Monitoring software
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GEHC DoseWatch
A multimodality, vendor independent tracking, recording and analyzing software of dosimetric data and much more… Tools to facilitate Dose Excellence:
• RadLex playbook to map site CT protocols to Affidea’s Standardized CT protocols in order to track compliance
• Data to assess correct patient positioning in FOV, mA modulation function, CTDIvol, DLP, SSDE, patient cumulative dose, BMI and more
• Definition, monitoring and justification of high-level dose alerts
• Custom made report for analysis of data, sent automatically via email to all relevant recipients
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High dose level alerts
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Alert system definition
Alerts defined by protocol. An alert is triggered when DLP recorded for the
specific patient examination is 2 x median DLP from the collected data on
the specific CT scanner and practice.
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DEP outcomes
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Justification, Standardization, Optimization - dashboard
2016-07-01 to 2016-07-31 2015-08-01 to 2016-07-31
No Alert Justified alert Not justified alert
JUST
IFIC
ATIO
N
2016-07-01 to 2016-07-31 2015-08-01 to 2016-07-31
Mapped protocols with accepted NS Not mapped protocols Mapped protocols with NS different thanaccepted values
NS = Number of series with DLP/(CTDIvol) >= 1.8
STAN
DAR
DIZ
ATIO
N
% not analysed exams
% analysed exams (mapped with standard NS)
2016-07-01 to 2016-07-31 2015-08-01 to 2016-07-31
Number of protocols p75 (CTDI or DLP)< DRL Number of protocols p75 (CTDI or DLP)> DRL
OPT
IMIZ
ATIO
N
Justification OptimizationStandardization
100.00 % 91.40 % 88.57 %
1.DASHBOARD
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Dose levels analysis
Device RPIDMax
acceptedNS
Protocol name # Exams
P25 of Maxseries
CTDIvol(mGy)
P75 ofMax series
CTDIvol(mGy)
Max CTDIDRL
(mGy)CTDI diff
P75 ofTotalDLP
(mGy.cm)
P25 ofTotalDLP
(mGy.cm)
VCT 64 RPID195 36.4 General
abdomen/pelvis max 3phases
46 5.56 9.35 17.00 -45.00 % 775.36 411.10
VCT 64 RPID248 4 5.8 TAP max 4 phases 34 7.04 13.69 15.00 -8.73 % 1066.92 603.93
VCT 64 RPID372 4 1.1 General Headincremental 20 50.79 51.83 55.00 -5.76 % 1566.40 782.86
VCT 64 RPID17 2 5.1 General Chest max 2series 19 4.37 7.99 10.00 -20.05 % 441.12 157.53
VCT 64 RPID280 2 5.4 Lung parenchyma 11 3.85 6.19 7.50 -17.47 % 224.55 144.78
VCT 64 RPID188 3 6.1 General abdomenmax 3 phases 8 6.19 11.57 14.00 -17.39 % 1086.68 417.23
VCT 64 RPID54 4 6.7 Urography - Kidneys 7 3.75 8.89 14.00 -36.50 % 841.02 294.48
VCT 64 RPID324 1 2.1 Sinusitis, facial trauma 5 5.13 5.15 10.00 -48.55 % 69.00 62.83
VCT 64 RPID38 2 3.1 Neck Space occupyinglesion 5 11.58 15.21 30.00 -49.30 % 846.84 607.49
VCT 64 RPID232 2 6.10 Pelvis max 2 phases 4 6.39 12.52 17.00 -26.38 % 743.80 349.99
VCT 64 RPID25 1 9.2 Lower extremitiestrauma 4 6.40 6.47 20.00 -67.68 % 146.66 105.08
VCT 64 RPID155 2 2.4 Inner ear 3 94.16 94.44 30.00 214.80 % 1240.61 831.12
VCT 64 RPID344 1 6.8 Renal stone 3 4.86 4.87 5.00 -2.60 % 220.49 207.71
VCT 64 RPID23 41.2 Head space occupying
lesion - inflammationincremental
2 50.56 51.83 55.00 -5.76 % 1604.00 1442.23
VCT 64 RPID98 2 2.2 Sinus space occupyinglesion 2 23.66 23.70 30.00 -21.00 % 663.43 554.34
VCT 64 RPID860 1 6.3 Abdomen/pelvis followup max 1 phase 2 3.64 4.12 17.00 -75.76 % 199.57 168.78
VCT 64 RPID87 3 6.9 Virtual colonography 2 3.85 3.86 11.00 -64.91 % 400.11 325.66
VCT 64 RPID1527 1 7.2 Lumbar SpineHerniation helical 2 20.43 22.96 50.00 -54.08 % 622.52 522.41
VCT 64 RPID21 1 3.5 Cervical Spine Trauma,Herniation 1 21.17 21.17 18.00 17.61 % 474.82 474.82
VCT 64 RPID16 1 5.3 Chest follow-up 1 3.81 3.81 7.50 -49.20 % 118.46 118.46
VCT 64 RPID1057 1 5.31 SnapShot Segment0.625 mm 66-75 BPM (LP) 1 15.27 15.27 55.00 -72.24 % 505.47 505.47
VCT 64 RPID960 1 5.5 Chest screening 1phase without contrast 1 3.82 3.82 3.00 27.33 % 130.14 130.14
VCT 64 RPID360 2 5.6 CTA Chest Aorta 1 28.17 28.17 15.00 87.80 % 728.27 728.27
VCT 64 RPID953 46.2 Abdomen focal liver
lesion/kidney max 4phases
1 9.82 9.82 14.00 -29.86 % 789.20 789.20
VCT 64 RPID956 46.5 Abdomen/pelvis with
delayed parenchymalphase, max 4 phases
1 10.57 10.57 17.00 -37.82 % 1144.16 1144.16
VCT 64 RPID242 4 7.1 Lumbar SpineHerniation incremental 1 26.65 26.65 40.00 -33.38 % 234.86 234.86
VCT 64 RPID27 2 9.3 Lower extremities softtissue 1 6.51 6.51 25.00 -73.96 % 364.35 364.35
This table shows a DRL analysis for all mapped protocols with accepted NS. The P75 values (Max series CTDIvol ) that are above theDRL threshold are displayed in red writing.
General protocols: Dose Reference Level (DRL) analysis - 2015-12-01 to 2015-12-31
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Device RPIDMax
acceptedNS
Protocol name # Exams
P25 of Maxseries
CTDIvol(mGy)
P75 ofMax series
CTDIvol(mGy)
Max CTDIDRL
(mGy)CTDI diff
P75 ofTotalDLP
(mGy.cm)
P25 ofTotalDLP
(mGy.cm)
VCT 64 RPID195 36.4 General
abdomen/pelvis max 3phases
46 5.56 9.35 17.00 -45.00 % 775.36 411.10
VCT 64 RPID248 4 5.8 TAP max 4 phases 34 7.04 13.69 15.00 -8.73 % 1066.92 603.93
VCT 64 RPID372 4 1.1 General Headincremental 20 50.79 51.83 55.00 -5.76 % 1566.40 782.86
VCT 64 RPID17 2 5.1 General Chest max 2series 19 4.37 7.99 10.00 -20.05 % 441.12 157.53
VCT 64 RPID280 2 5.4 Lung parenchyma 11 3.85 6.19 7.50 -17.47 % 224.55 144.78
VCT 64 RPID188 3 6.1 General abdomenmax 3 phases 8 6.19 11.57 14.00 -17.39 % 1086.68 417.23
VCT 64 RPID54 4 6.7 Urography - Kidneys 7 3.75 8.89 14.00 -36.50 % 841.02 294.48
VCT 64 RPID324 1 2.1 Sinusitis, facial trauma 5 5.13 5.15 10.00 -48.55 % 69.00 62.83
VCT 64 RPID38 2 3.1 Neck Space occupyinglesion 5 11.58 15.21 30.00 -49.30 % 846.84 607.49
VCT 64 RPID232 2 6.10 Pelvis max 2 phases 4 6.39 12.52 17.00 -26.38 % 743.80 349.99
VCT 64 RPID25 1 9.2 Lower extremitiestrauma 4 6.40 6.47 20.00 -67.68 % 146.66 105.08
VCT 64 RPID155 2 2.4 Inner ear 3 94.16 94.44 30.00 214.80 % 1240.61 831.12
VCT 64 RPID344 1 6.8 Renal stone 3 4.86 4.87 5.00 -2.60 % 220.49 207.71
VCT 64 RPID23 41.2 Head space occupying
lesion - inflammationincremental
2 50.56 51.83 55.00 -5.76 % 1604.00 1442.23
VCT 64 RPID98 2 2.2 Sinus space occupyinglesion 2 23.66 23.70 30.00 -21.00 % 663.43 554.34
VCT 64 RPID860 1 6.3 Abdomen/pelvis followup max 1 phase 2 3.64 4.12 17.00 -75.76 % 199.57 168.78
VCT 64 RPID87 3 6.9 Virtual colonography 2 3.85 3.86 11.00 -64.91 % 400.11 325.66
VCT 64 RPID1527 1 7.2 Lumbar SpineHerniation helical 2 20.43 22.96 50.00 -54.08 % 622.52 522.41
VCT 64 RPID21 1 3.5 Cervical Spine Trauma,Herniation 1 21.17 21.17 18.00 17.61 % 474.82 474.82
VCT 64 RPID16 1 5.3 Chest follow-up 1 3.81 3.81 7.50 -49.20 % 118.46 118.46
VCT 64 RPID1057 1 5.31 SnapShot Segment0.625 mm 66-75 BPM (LP) 1 15.27 15.27 55.00 -72.24 % 505.47 505.47
VCT 64 RPID960 1 5.5 Chest screening 1phase without contrast 1 3.82 3.82 3.00 27.33 % 130.14 130.14
VCT 64 RPID360 2 5.6 CTA Chest Aorta 1 28.17 28.17 15.00 87.80 % 728.27 728.27
VCT 64 RPID953 46.2 Abdomen focal liver
lesion/kidney max 4phases
1 9.82 9.82 14.00 -29.86 % 789.20 789.20
VCT 64 RPID956 46.5 Abdomen/pelvis with
delayed parenchymalphase, max 4 phases
1 10.57 10.57 17.00 -37.82 % 1144.16 1144.16
VCT 64 RPID242 4 7.1 Lumbar SpineHerniation incremental 1 26.65 26.65 40.00 -33.38 % 234.86 234.86
VCT 64 RPID27 2 9.3 Lower extremities softtissue 1 6.51 6.51 25.00 -73.96 % 364.35 364.35
This table shows a DRL analysis for all mapped protocols with accepted NS. The P75 values (Max series CTDIvol ) that are above theDRL threshold are displayed in red writing.
General protocols: Dose Reference Level (DRL) analysis - 2015-12-01 to 2015-12-31
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Powered by DoseWatchglobal solution for patient dose tracking and optimization in medical imaging
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Consolidated data analysis example
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General Head incremental protocol – RPID 372
Data period 01/02/16 – 31/03/16
Number of countries 7
Number of CT departments 21
Number of CT models 13
Total number of examinations 4,275
Max accepted number of series 4
Median of most used number of series 1
Excluded protocols < 20 examinations
Excluded series/examinations Non diagnostic and tests
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Dashboard
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Alerts root – cause analysis
31%
20% 17%
16%
15%
1%
Additional phases
Patient movement
Overweight
Additional protocol
Over length acquisition
Wrong protocol
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Standardization
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CTDIvol per county
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DLP per country
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CTDIvol per CT model
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Challenges and tips
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Challenges
§ Resistance to change
§ Fear of misdiagnosis
§ Assessing image quality § National Health System rules
§ Unclear referral notes
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Tips
§ Choose your teams wisely and encourage collaboration § Review your goals and reassess when required
§ Do not make big changes, people need time to adjust
§ Make sure your results are accurate before you implement changes § Meet and communicate frequently
§ Inspire, be enthusiastic and reward your teams for their work
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