csir model paper ii

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Model Test Paper - 2


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Part-A

1. A bat was flying with the speed of 0.5 m/s, produced an ultrasound wave with the speed of 5m/s. It received the signal back exactly after 20 sec. how far is the object from the bat at thatpoint?

A. 100 mB. 50 m

C. 25 mD. 40 m

2. What is the angle covered by the hour hand between 4.10 PM to 4.10 AM?A. 300B. 400

C. 360D. 6

3. In how many ways you can build a team of 2 players, from 20 players?A. 100B. 190

C. 120D. 290

4. The ratio between the three angles of a quadrilateral is 13: 9: 5 respectively. The value of thefourth angle of the quadrilateral is 36. What is the difference between the largest and thesecond smallest angles of the quadrilateral?

A. 104

B. 108

C. 72

D. 96

5. If A = x% of y and B = y% of x, then which of the following is true?A. A is smaller than B.B. A is greater than B

C. A and B are equalD. If x is smaller than y, then A is greate

than B.

6. If the radius of a circle is diminished by 10%, then its area is diminished by:A. 10%B. 19%

C. 20%D. 36%

7. The reflex angle between the hands of a clock at 10.25 is:

A. 180B. 192 1/2

C. 195D. 197 1/2

8. A boat running upstream takes 8 hours 48 minutes to cover a certain distance, while it takes 4hours to cover the same distance running downstream. What is the ratio between the speed ofthe boat and speed of the water current respectively?

A. 2 : 1B. 3 : 2

C. 8 : 3D. Cannot be determined

9. A hall is 15 m long and 12 m broad. If the sum of the areas of the floor and the ceiling is equal tothe sum of the areas of four walls, the volume of the hall is:

A. 720

B. 900

C. 1200

D. 1800

10. On a certain exam the only grades awarded were 80 and 100. If the 10 students completed theproject and the average of their grades were 94. How many eared 100?

A. 2B. 3

C. 5D. 7

11. If 2x=32. What is x2?A. 5B. 14

C. 25D. 100


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12. An alone can do a piece of work in 6 days and B alone in 8 days. A and B undertook to do it forRs. 3200. With the help of C, they completed the work in 3 days. How much is to be paid to C?

A. Rs. 375B. Rs. 400

C. Rs. 600D. Rs. 800

13. The angle of elevation of a ladder leaning against a wall is 60 and the foot of the ladder is 4.6 m

away from the wall. The length of the ladder is:

A. 2.3 m

B. 4.6 m

C. 7.8 m

D. 9.2 m

14. Find out how the key figure (X) look will like after rotation

A. 1

B. 2

C. 3

D. 4

15. 4 men and 6 women can complete a work in 8 days, while 3 men and 7 women can complete it in

10 days. In how many days will 10 women complete it?

A. 35

B. 40

C. 45

D. 50

Part-B16. A DNA sequence, which is homologous to active gene, but not having any function

A. IntronB. Interrupted sequences

C. PseudogenesD. Non coding repeats

17. Which of the following statement is true?A. Satellite DNA is a part of chromosome localized to centromere onlyB. Satellite DNA was discovered as distinct band on agarose gelC. Satellite DNA contains different base composition from rest other DNA sequencesD. All repetitive DNA are a part of satellite DNA.

A. Only AB. Only C

C. Only DD. Both A and D

18. Around which prehistoric time scale, Homo sapiens evolved from previous species?A. Pleistocene epochB. Eocene epoch

C. Oligocene epochD. Jurassic period

19. Bat use echolocation to locate the prey. The right ear of the bat picked up the wave slightlybefore being recognized by the left ear. This is interpreted as

A. The prey is on right sideB. The prey is on left side

C. The prey is movingD. The prey is on left side and bat is

moving over it.20. In non-human primates, the dominant male shows

A. More ability to capture preyB. PolygynousC. Parental care

A. Only BB. Only c

C. Both A and BD. All the above


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21. The phenotype is governed by both genotype and environment. Sometimes we find phenotypeis not inheritable and is produced by organism exposed to a particular environment. This is dueto

A. PleotropyB. Phenocopy

C. PsedogenesD. Complementation

22. What is the minimum number of transesterification reactions required to splice out an intronfrom an mRNA transcript?

A. 1B. 2

C. 3D. 4

23. Match the following Proteins involved in DNA replication with their functions:Protein Functions

1. DnaA A. Required for DnaB binding at origin

2. HU B. Methylates 5 GATC sequences at oriC

3. DnaC C. Recognizes ori sequences; opens duplex at specific sitesin origin

4. Dammethylase

D. DNA binding protein; stimulates initiation

A. 1-A, 2-C, 3-D, 4-BB. 1-C, 2-D, 3-A, 4-B

C. 1-B, 2-A, 3-C, 4-DD. 1-D, 2-C, 3-A, 4-B

24. Which of the following processes allows activation of transcription by changing theaccessibility of chromatin to transcription factors?

A. Extensive methylation of DNAB. Binding of protamines to DNA

C. Action of ATPase chromatinremodeling complexes

D. Formation of a Barr body

25. Rifampicin is an important antibiotic used to treat tuberculosis, as well as other mycobacterialdiseases. Some strains of Mycobacter ium tubercu los is, are resistant to rifampicin, these strainbecome resistant by which of the following mechanisms?

A. Mutations in the MDR-type ABC transporter, which pumps the drug out of the Mycobacterium.B. By production of rifamycin oxidase (RO).C. Mutations that alter rpoB gene, involved in synthesis of subunit of RNA polymerase.D. Mutations in the sigma () subunit of RNA polymerase.

26. E. coli cells are growing in medium containing lactose but no glucose. A mutation is introducedsuch that it prevents binding of CRP to its binding site near the lac promoter. What will be theconsequence of such type of mutation?

A. When glucose is introduced in the medium, the cells will not be able to utilize glucose.B. The lac operon will be constitutively expressed irrespective of the concentration of glucose in

the external medium.C. The lac operons expression will decrease irrespective of the concentration of lactose in the

surrounding medium.D. The lac operons expression will be halted when glucose concentration is high.

27. Which of the following is not a pathway for biosynthesis of Auxins?A. Indole-3-pyruvic acid pathwayB. Tryptamine pathwayC. Indole-3-acetonitrile pathwayD. Oxindole-3-acetic acid pathway

28. Match the Following as per the importance of stratification taking place in lake ecosystem?

Column A Column B


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1. gradient at edges of biomes a. epilimnion

2. vertical temperature gradient in lake b. hypolimnion

3. upper layer of warm water c. ecocline4. rich in organic nutrients d. thermocline

5. lower layer of water at 40 F. (about 4C.)

e. eutrophic

f. oligotrophic

A. c,d,a,e,bB. d,c,a,e,f C. b,c,a,e,fD. a,b,d,e,f

29. Arrange the biomes as per the characteristics peculiar to itColumn A Column B

1. Biome including grass, hyenas,antelopes, zebras, and lions.

a. savannah

2. This biome exhibits the greatestdiversity of plant species.

b. taiga

3. The subsoil of this biome ispermanently frozen

c. deciduous forest

4. This biome can be recognized by its

coniferous forests and relativelyinfertile acidic soil.

d. tundra

e. tropical rain forest

f. temperate grassland

A. a,e,d,bB. a,b,d,e

C. b,d,a,eD. a,e,b,d

30. Mark out the appropriate difference between r and k selected speciesA. R- Density dependent regulation K Density independent regulationB. R- abiotic factors K- biotic factorsC. Rlow r max K- High r maxD. Both b) and c)

31. In syncytial specification, the fates of cells can be determined by ____ within the egg cytoplasmA. gradients of morphogensB. Ectoderm

C. MesodermD. Endoderm

32. Competence is the ability to bind and to respond to the inducers, and it is often the result of ainducing protein. __________ are inducing proteins that bind to cell membrane receptors incompetent cells.

A. Paracrine factorsB. Juxtacrine factors

C. neurotransmitters,D. cytokines

33. Mammalian sperm bind to the zona pellucida before undergoing the acrosome reaction. In the

mouse, this binding is mediated by ____________ and one or many sperm proteins thatrecognize it.

A. ZP3 (zona protein 3)B. ZP2 (zona protein 2)

C. ZP1 (zona protein 1)D. ZP4 (zona protein 4)

34. Media containing spores can be sterilized byA. pasteurizationB. UV

C. dry heatD. tyndallization

35. Two proteins have same molecular weight and same isoelectric focusing .The best way toseparate them will be


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A. Ion exchange chromatographyB. Gel filtration chromatography

C. Reverse phase chromatographyD. Chromato-focussing

36. The separation principle of dialysis isA. diffusionB. charge

C. turbulenceD. solubility

37. EcorI restriction enzymes produce cohesive (sticky) ends. This means that theyA. Cut both DNA strands at the same base pairB. Cut in regions of high GC content,leaving ends that can form more hydrogen bonds than ends

of high AT contentC. Make a staggered double stand cut, leaving ends with a few nucleotides of single-standed

DNA protruding.D. Stick tightly to the ends of the DNA they have cut.

38. In recombinant DNA technology, invitro packing is used toA. Cut a desired region out of the bacterium`s chromosome.B. Ensure that genetically engineered bacteria are not accidentally released into the environment.C. Incorporate recombinant DNA into infectious bacteriophage particles.D. Very effective

39. Which of the following does not apply to the construction or use of a DNA library?A. Many segment of DNA from a cellular genomes are clonedB. Specialized DNA libraries can be made by cloning DNA copies of mRNAs.C. The DNA copies of mRNA found in a cDNA library are made by reverse transcriptase.D. Genomic libraries are better for expressing gene products than cDNA libraries.

40. Two sites that are often used to grow animal virusesA. Chorioallantoic membrane and allantoic cavityB. Yolk sac and amniotic cavityC. Amniotic cavity onlyD. Yolk sac only

41. Which of the following organism produce hydrogen peroxide as virulence factorA. MycoplasmaB. Streptococcus species

C. Salmonella spD. Pseudomonas

42. Glucose effect isA. Higher the glucose concentration cause decreased cAMPB. Lower the glucose concentration caused decreased the cAMPC. Higher the glucose concentration caused increased the cAMPD. Lower glucose concentration cause increased cAMP

43. Increased activity of calcitonin is seen during

A. High blood calcium levelB. Low blood calcium level

C. Decreased osteoclast activity.D. All of the above

44. Andrenergic neurons areA. sympathetic post-ganglionic neuronB. sympathetic pre-ganglionic neuronC. parasympathetic post-ganglionic neuronsD. parasympathetic-preganglionic neurons

45. Anti inflammatory effect is shown by


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A. CortisolB. Aldosterone

C. EpinephrineD. Norepinephrine

46. Which of the following antigens can be processed by TAP deficient cells? A. Any antigen as antigen processing is independent of TAP proteins.B. Only endogenous antigensC. Endogenous and non proteinaceous antigensD. Only exogenous antigens

47. Which of the following cytokines mediates activation of T helper cells by macrophages? A. IL-2B. IL-4

C. IFND. IL-12

48. Polymers of D-amino acids are poor immunogens becauseA. The degradative enzymes within antigen-presenting cells can degrade only proteins

containing L-amino acids.B. MHC cannot present polymers of D amino acids.C. APCs cannot express an MHC with the polymers.D. No polymer can activate cell mediated immunity.E. Only Tc cells get activated by polymers of D amino acids.

A. B and DB. A and E

C. C and ED. A and B

49. An Enzyme which binds to the substrate at Gly 60 position is inhibited by compound X, X bindsto the substrate at Asp 72. What would be the effect of this inhibitor on the Vmax and Km of thereaction?

A. Vmax and Km will increase drasticallyB. Vmax remains the same but Km

decreases.

C. Both Vmax and Km decreaseD. No effect on Vmax and Km

50. Familial glucocorticoid deficiency and isolated glucocorticoid deficiency are caused due toA. Decrease in the carbohydrates in the

foodB. Defect in ACTH receptor

C. Defect in adrenal cortex

D. Defect in glucocorticoid receptor.

PART-C

51. Bacteriophage is a small virus with 9 genes coding for 9 different polypeptide sequences. Whencounted the weights of all polypeptides, it was calcultated that the genome need to haveminimum 6078 nucleotides, but it was found to have only 5387 nucleotides. 5387 bases can noway produce 9 polypeptides as per our gene knowledge. What may be going on in the viragenome that it could code for 9 polypeptides with fewer than needed nuclotides?

A. May be the calculations of 9 polypeptides is wrong, it is coding for only 8 polypeptides, for which5387 bases are enough

B. May be calculations of genome size is wrong, it is actually 6078 basesC. The genes may be overlapping in the virus, so that they can produce 9 peptide sequencesD. The virus has extrachromosomal DNA.

52. Chromosomes are always easy to mutate. Imagine a gamete with a small arm of chromosome 2is missing. This chromosome containing gamete fused with a normal gamete and produced aoffspring. The recessive gene present on the nondeleted chromosome, now started showing itsphenotypes, as its counterpart on deleted chromosome was lost. This phenomenon is due to

A. PseudogenesB. Pseudo dominance

C. Exon shfflingD. Suppressor mutation.


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53. Imagine we have only with One species of each produced plant, herbivore, carnivore anddecomposer with sufficient light source. All in a bioshpere interdependent on each other. Willthis system work?

A. Yes, it will as all the essential components are presentB. No, it will never work as comsumers will be more than the producersC. No, it will not work for long time, as with the threat to or death of one of the species, entire

system will break down.D. No, it needs Human who produces enough CO2 and other chemicals for plant survival.

54. It is seen in lions, that the Alpha lion mates with almost all the female lions and builds a biggerpride. The female lions allow the copulation to only the lion which is stronger and has largerterritory. Hence other male lions are always under conflict for females. Which of the followingcan be a suitable explanation for the female lion behavior?

A. Females are bigger cats and hence need more space for themB. More territory means more food availableC. More territory means it will ensure a larger area of healthy and comfort for the offsprings to

grow, hence reproductive success.D. Female like to go on walk in larger territory.

55. Which of the following are not types of phenolic plant secondary metabolites?A. LigninB. Caffeic acid

C. CardenolidesD. Anthocyanin

56. Which one of the following sugar phosphates is not part of the pool of readily interconvertiblemetabolites used by the plant cell?

A. Dihydroxyacetone phosphateB. Fructose 2,6-bisphosphate

C. Glucose 1-phosphateD. 6-phosphogluconate

57. Following are statements regarding the plant hormone ethylene.A. Ethylene biosynthetic pathway is also called as the Yang cycle which involves the amino

acid Glycine and an intermediate ACC.

B. Auxins promote synthesis of Ethylene.C. Ethylene can be measured by GC.D. Fruits are stored under high concentration of CO2, to delay ripening as CO2 acts as Ethylene

antagonist.The correct combination of statements is

A. A, B, CB. A, B, D

C. B, C, DD. A, C, D

58. The importance of dark period in photoperiodism is that it can be made ineffective byinterruption with a short exposure to light, called a night break. In contrast, interrupting a longday with a brief dark period does not cancel the effect of the long day. Which of the followingstatements are correct?

A. It is possible to induce flowering in SDPs with light periods longer than the critical valueprovided that the light period is followed by sufficiently long nights.

B. SDPs will not flower if short days are followed by short nights.C. LDPs will not flower if short days are followed by short nights.D. LDPs will not flower if day breaks are introduced in day time, followed by short nights.

A. A and BB. B and C

C. A and DD. B and D

59. Host parsitoid interactions are been given by the following equation:


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Where is the per-capita growth rate of hosts in the absence of parasitoids and c is theconversion efficiency . What is f(Nt, Pt) ?

A. Effect of parasite on HostB. Effect of Host on Parasites

C. Probability of InfectionD. Number of Host and parasites

present in the environment

60. Metapopulation Concept is given by:

Where m is the rate of colonization, and e is the rate of extinction and e


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blindness

D. Phosphates iv. BOD

The correct match is:A. A ii, B i, C iv, D iiiB. A iii, B ii, C iv, D iC. A iii, B iv, C i, D iiD. A iii, B I, C iv, D iE.

65. Match each features of the plasmid pBR322

I. am pRsequence a. permits selection of bacteria containing the plasmidII. or i sequence b. a sequence required invitro packing

III. tetR c. origin of replicationIV. BamHIsequenced. cleavage of the plasmid here doesnt affect antibiotic resistance.V. pstIsequence e. insertion of foreign DNA here permits identification of recombinants

A. I B, II C, III D,IV A

B. I A, II C, III E,IV B

C. I E, II C, III D,IV B

D. I A, II C, III B,IV E

66. Match the genes involved in plant cell transformation by agrobacterium.I. Vir A. segment of the Ti plasmid transferred to the plant genome

II. Cytokinin B. genes that involved in transfer of a segment of Ti to plantIII. Opine C. a plant growth harmoneIV. T DNA D. an unsual metabolite that can be metabolized only bacteria.

E. Encodes enzyme required to metabolize auxinA. I B, II C, III D,IV AB. I A, II C, III E,IV B

C. I E, II C, III D,IV BD. I A, II C, III B,IV E

67. If core body temperature rises above normal, which of the following would occur to cool the

body? (1) dilation of vessels in the skin, (2) increased radiation and conduction of heat to the

environment, (3) increased metabolic rate, (4) evaporation of perspiration, (5) increased

secretion of thyroid hormones.

A. 3, 4, and 5

B. 1, 2, and 4

C. 1, 2, and 5

D. 1, 2, 3, 4 and 5

68. The four refracting media of the eye, listed in the sequence through which light passes, are:1. Vitreous body2. Lens3. Aqueous humor4. Cornea

A. 1,2, 3, 4B. 4, 1, 2, 3

C. 4, 3, 2, 1D. 2, 3, 4, 1


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69. The arrow in graph represents

A. Stationary phase in diauxic growthB. Stationary phase of normal growth of

organism in glucose

C. Lag phase of diauxic growth curveD. Log phase of normal growth curve

with limiting factor.

70. A Mutation in wee1 protein is induced such that its phosphorylation activity is lost. The effectof this would be

A. Cdc2 is active, therefore cell would enter mitosis

B. Cdc2 to is inactive, therefore cell cycle would arrest at G2.C. Cdc1 to is inactive, therefore cell cycle would arrest at G1.D. Cdk2 to is inactive, therefore cell cycle would arrest at GS.

71. Which of the following statement is false?A. The and angles for every amino acid residue in a perfect helix would fall at a single point

in a Ramachandran plot.B. Many Combinations of and angles are impossible in polypeptides because of steric

interferenceC. The and angles in Ramachandran plot can each vary over a range of 360D. The and angles in a Ramachandran plot represent the possible angles of rotation around

the peptide bond

72. TLRs are transmembrane proteins, expressed on the cell surface and the endocyticcompartment and recognize pathogen-associated molecular patterns (PAMPs).TLR9 targetsCpG sequences in DNA molecules.The effect is attraction of phagocytes, macrophages,(cellmembrane) dendritic cells and it induces secretion of several cytokines. TLR9 show specificityfor bacterial cells but not for host cells because

A. TLR9 recognizes methylated CpG sites which are in abundance in bacterial genomeB. TLR9 recognizes unmethylated CpG sites which are relatively rare in vertebrate genomeC. TLR9 recognizes methylated CpG sites which are relativly rare in bacterial genomeD. TLR9 recognizes unmethylated CpG sites which are in abundance in vertebrate genome.

73. In an experiment setup involving B cells, mutations are introduced in genes encoding

oligosaccharyl transferase. These B cells, along with unmutated B cells, are stimulated toproliferate and IgGs obtained from these cells are subjected to digestion with papain. It wasobserved that

a. IgGs derived from mutated B cells are resistant to papain digestionb. IgGs derived from unmutated B cells are resistant to papain digestionc. IgGs derived from mutated B cells are more sensitive to papain digestiond. IgGs derived from unmutated B cells are more sensitive to papain digestion

Correct combination of statements isA. A and BB. B and C

C. C and DD. A and D


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74. The mythical Gram-negative extracellular bacterium, Stevensonella pulmonensis, causes adisease called acute miamiosis as the result of its thick capsule and production of a toxin thatcauses buildup of fluid in the lungs. Which immune mechanism(s) would be effective againstthis bacterium?

A. Antibody specific for the toxin would be helpful because it might neutralize the toxin bypreventing its interaction with cellular targets.

B. Activated macrophages would be required because these cells would be able to preventintracellular multiplication of this parasite

C. Opsonizing antibody specific for capsular antigens might be helpful because it would be able toenhance phagocytosis of the bacterium by neutrophils, which could then kill it intracellular.

D. ADCC mediated by NK cells would be a primary line of defense against this pathogen becauseit would provide for its complement mediated lysis.

75. Which of the following statements, regarding platelet activating factors is/are incorrect?A. It is an ether lipidB. It is released from leucocytes and lead to the release of serotonin.C. It activates inflammatory responsesD. It subdues the inflammatory responses.E. It plays a role in allergic responses.

A. A and D

B. A and E

C. Only D

D. C and E

--END of Questions --

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73. B. B and C74. C. Opsonizing antibody specific for capsular

antigens might be helpful because it wouldbe able to enhance phagocytosis of thebacterium by neutrophils, which could thenkill it intracellular.

75. C. Only D

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