cronic limfoblastik leukemia

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CHRONIC LIMFOBLASTIK LEUKEMIA Ulfa Hasani Al-adibah 030.08.246

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Page 1: Cronic Limfoblastik LEUKeMIA

CHRONIC LIMFOBLASTIK

LEUKEMIA

Ulfa Hasani Al-adibah030.08.246

Page 2: Cronic Limfoblastik LEUKeMIA

IDENTITY • Mr .TName• 42 years oldAge • MaleSex • Cilamaya Kulon RT/RW 09/04 KarawangAddress • elementary schoolEducation • Labour Occupation • MoeslemReligion • MarriedMarital status• September 23th 2012Admitted • SundaneseEthnic

Page 3: Cronic Limfoblastik LEUKeMIA

AnamneseAutoanamnese, taken on Wednesday 27

september , 2012

• Vomiting of blood since 1 month before hospitalizedMain

Complaint• Dizziness• fatigue• Fever• nausea• Shortness of breath• Gum bleeding• Coughing up blood

Additional Complaint

Page 4: Cronic Limfoblastik LEUKeMIA

Patient came to Emergency Unit of Karawang City Hospital with complaint of vomiting of blood since 1 mounth before hospitalized.

He also felt dizziness , intermittent fever for 1 month and felt fatigue,nausea, shortness of breathing, gum bleeding since 2 month before hospitalized.

Patients complain vomiting of blood while in hospital and he also complained of bleeding gums. The blood that came out a dark red,and the volume is not too much.

Patient also say that his legs felt pain.

History of Present Disease

Page 5: Cronic Limfoblastik LEUKeMIA

HISTORY OF PAST ILLNESS

SAME ILLNESS BEFORE (-)

HYPERTENSION( - )

DIABETES( - )

KIDNEY DISEASE( - )

ASTHMA( - )

ALLERGY

( - )

Page 6: Cronic Limfoblastik LEUKeMIA

FAMILY HISTORY

SAME DISEASE( - )

HYPERTENSION( - ) DIABETES

( - )

KIDNEY DISEASE

( - )

ASTHMA( - )

HEART DISEASE (-)

Page 7: Cronic Limfoblastik LEUKeMIA

Alcohol consumption (-)

Smoking (+)

Routine Excercise (-)

Tattoos (-)

Blood Transfusion (-)

Injected drugs (-)

Traditional beverages (-)

Habits History

Page 8: Cronic Limfoblastik LEUKeMIA

• Moderately ill

General appearance

• Compos mentis

Consciousness

General Condition

Page 9: Cronic Limfoblastik LEUKeMIA

VITAL SIGNS Blood Pressur

e• 100/6

0mmHg Heart

Rate• 90x/mins

Respiration Rate• 20x/mins

Temperature• 35,8 ͦ

C

Page 10: Cronic Limfoblastik LEUKeMIA

Physical Examination

• Normocephali Head• Anemic conjunctiva +/+• Icteric sclera -/-Eyes• Lip: cyanosis(-)• Pharynx: hyperemic (-),

symmetrical, uvula at midlineMouth• Lymph gland & Thyroid gland is not

palpableNeck

Page 11: Cronic Limfoblastik LEUKeMIA

Thorax Examination

I : Symmetrical Pal : Equal vocal resonancePer : Sonor in both lungsA : Vesicular breath sound in both lung,ronchi (-/-),wheezing (-/-)

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INSPECTION

Ictus cordis is invisible

PALPATION• Ictus cordis is palpable at 5th ICS LMCS

PERCUTION• Right heart border: ICS III-V LSD• Left heart border: ICS V 1cm medial LMCS• Upper heart border: ICS III LPSS

AUSCULTATION• Regular I - II absence of murmurs and gallop in

heart’s sound

Heart Examination

Page 13: Cronic Limfoblastik LEUKeMIA

ABDOMINAL EXAMINATION

Inspection : Brown skin, Flat Palpation : Sociable (-),tenderness (+) splenomegali (+): palpable at

S4

Percussion : pain present on abdominal percussion Sounds dull

Auscultation :Bowel sound (+), arterial bruit (-), venous hum(-)

Page 14: Cronic Limfoblastik LEUKeMIA

Extremity Examination

Warm acrals

Oedema

Purpura

+ ++ +

- -- -

- -- -

Page 15: Cronic Limfoblastik LEUKeMIA

LABORATORY FINDINGseptember , 23 2012

Blood Results Normal

Hb 2,4 12-14 g/dl

Ht 8 37-43 %

Trombocyte 114.000 150.000-450.000

Leucocyte 120.000 5000-10.000

MCV 111 82-92

MCH 30 27-31

MCHC 27 32-35

RDW 28 11,6 – 14 %

Page 16: Cronic Limfoblastik LEUKeMIA

Peripheral Blood SmearSeptember 23th 2012

Page 17: Cronic Limfoblastik LEUKeMIA

USG Abdomen

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Page 19: Cronic Limfoblastik LEUKeMIA
Page 20: Cronic Limfoblastik LEUKeMIA
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Interpretation

Page 22: Cronic Limfoblastik LEUKeMIA

RESUMEAnamnese

• Fatigue• Dizziness• Fever • Nausea • Vomiting of blood

• Gum bleeding

• Shortness of breath

• Bone pain

Physical Examinatio

n• Anemic conjungtiva +/+

• splenomegali

Adjuvant Test

• Blood Test• Hb : 2,4 g%• Ht: 8 %• Leukocyte :

120.000• Trombocyte:

114.000• Peripheral

Blood Smear: suspect cronic limfloblastik leukimia

Page 23: Cronic Limfoblastik LEUKeMIA

Chronic limfoblastic leukemia Prolimfositik Leukimia Hairy cell Leukimia Chronic cell T Leukimia Mantle cell lymphoma Limfoplasmasitic leukemia

Differential Diagnosis

Page 24: Cronic Limfoblastik LEUKeMIA

Working Diagnosis

Cronic Limfloblastik Leukemia

Page 25: Cronic Limfoblastik LEUKeMIA

Bone marrow aspiration

Suggested Examination

Cytochemical staining

Page 26: Cronic Limfoblastik LEUKeMIA

Treatment

IVFD NaCl 0,9% 20 tpm

PRC Transfusion 5

unit

Kalnex 3x 500 mg IV

Ceftriaxone 2x 1gr IV

Omeprazole 1x1

Chemotherapy

Page 27: Cronic Limfoblastik LEUKeMIA

PROGNOSIS

Ad sanationam :

Dubia ad malam

Ad Fungsionam :

Dubia ad

malam

Ad Vitam :

Dubia ad malam

Page 28: Cronic Limfoblastik LEUKeMIA