chc shs 20170503 fumikohoeft pdf · 5/3/2017 · background | resilience framework | cognitive...
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5/3/17
1
Cognitive&Socio-EmotionalResilienceinDyslexia
FumikoHoeftMDPhD
[email protected] |@fumikohoeft |profiles.ucsf.edu/fumiko.hoeftUC6-StanfordPrecisionLearningCenter(PrecL.org)
UCSFLaboratoryforEducationalNeuroscience(brainLENS.org)UCSFDyslexiaCenter(dyslexia.UCSF.edu)
UCSFDept ofPsychiatry|WeillInstituteforNeurosciencesYale/UConnHaskinsLaboratories
R01HD078351 (Hoeft, UCSF)R01HD086168 (Hoeft/Pugh, UCSF/Haskins)P01HD001994 (Rueckl, Haskins/UConn) R01MH104438 (Nordahl, UCDavis/MIND) R01MH103371 (Amaral, UCDavis/MIND)
SUPPORTERS
Toney & Potter Family
NSF1540854 SL-CN (Gazzaley/Uncapher, UCSF)
CHC- SandHillSchool|05.03.2017 Whyiseachchildsodifferent?Howcanweensuresuccessineachchild?
Taiga(8)“INFORMATIONSEEKER”
Kaito (6)“STORYMAN”“3DMAN”
WeakreaderAvoidsreading
Avidreader
Visuo-spatialWritinglabelsforspecimenbox
Empathic
Spiderman- Halloween
Analytic
Red/Whitebloodcell- Halloween
JackHorner,apaleontologistfromJurassicPark/World
NOWTechnicalAdvisorofJurassicPark(=Dr.AlanGrant)MacArthurGeniusAward(‘86)Romer-SimpsonMedal(’13)
THENSeverelydyslexicGraduatedhighschoolwithD---Failedcollege7timesNevergraduatedGPA0.06(Honorarydoctorate,’06) 3
JackHorner,apaleontologistfromJurassicPark/World
NOWTechnicalAdvisorofJurassicPark(=Dr.AlanGrant)MacArthurGeniusAward(‘86)Romer-SimpsonMedal(’13)
THENSeverelydyslexicGraduatedhighschoolwithD---Failedcollege7timesNevergraduatedGPA0.06(Honorarydoctorate,’06)
Importanceofresilience
Importanceofenvironment&community
Importanceoflookingatanindividualasawhole(includingliteracy butalsoothercognitiveandsocio-emotionalaspects) 4
Outline• BACKGROUND
– Dyslexiacostlyinmanydimensions– Importanceofanintegrativeapproach
• TODAY’SFOCUS– Theresilienceframeworkofdyslexia– Cognitiveresilience– Socio-Emotionalresilience
• CONCLUSION,OTHERWORK(e.g.EnglishLearners)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Outline• BACKGROUND
– Dyslexiacostlyinmanydimensions– Importanceofanintegrativeapproach
• TODAY’SFOCUS– Theresilienceframeworkofdyslexia– Cognitiveresilience– Socio-Emotionalresilience
• CONCLUSION,OTHERWORK(e.g.EnglishLearners)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
5/3/17
2
NeuroscienceofDyslexia
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Xia,Hancock,Hoeft.Language&LinguisticCompass.2017.
Regions&circuitsdysfunctionalindyslexia(function,structure,temporaldynamics,neurochemicals,relationwithriskgenes,etc)
• Evenwhencomparedtoreading-matched“normal”readers:Hoeft etal.JNeurosci ’06;PNAS’07
• Regardlessofwritingsystem(Chinese):Xiaetal.Neuropsychologia ’16;Rueckl etal.PNAS‘15
• At-riskpre-readers(withfamilyhistory):Blacketal.NeuroImage ‘12;Hosseinietal.NeuroImage ’13;Vandermosten Hoeft Norton.Curr Opin Beh Sci.‘16
• Regardlessofidentificationcriteria:Tanakaetal.Psychol Sci ’11
• In”normal”readerswithhighIQ(GiftedDyslexics,2ekids):Hancocketal.TiNE ’17
Phonological(Temporo-Parietal)
Orthographic(Occipito-Temporal)
Compensatoryfrontalarticulatory&righthemispherenetworks:Hoeftetal.PNAS‘07,PNAS’11;HancockRichlan Hoeft.Neurosci Beh Rev‘16
Articulatory(Frontal)
ARTICULATORY(InferiorFrontalRegion)
PHONOLOGICAL(Temporo-
ParietalRegion)
ORTHOGRAPHIC(Occipito-
TemporalRegion)
ReadingCircuits:DomainGeneral+SpecificCircuits
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Black,Xia,Hoeft.Language&LinguisticCompass
IFGorb
IFGopPreCG
IFGtri
aSMGpSMG
AGACC
DLPFC
pSTG
mFG
OrthographyPhonologySemanticsSentence / SyntaxVocabularyAttentionExecutive Function
Major Reading Systems
aFGTemporalPole
ACC:anteriorcingulatecortex;AG:angulargyrus;DLPFC:dorsolateralprefrontalcortexincludingsuperior/middle/dorsalinferiorfrontalgyri;a/mFG:anterior/midfusiform gyrus (visualwordformarea,VWFA);IFGorb/tri/oper:inferiorfrontalgyrus orbitalis,triangularis,opercularis;PPC:Posteriorparietalcortex;PreCG:precentralgyrus;a/pSMG:anterior/posteriorsupramarginal gyrus;pS/MTG:posteriorsuperior/middletemporalgyrus;
PPC
pMTG
ATTENTION
SENTENCE/SYNTAXSEMANTIC
EXECUTIVEFUNCTION(CONTROL/MEMORY) VOCABULARY
CostofDyslexia
Risks
Dyslexia
POOROUTCOME: ReadingComprehension,EducationalAttainment,PsychosocialAdjustment
DLPFC
ORTHOGRAPHIC
PHONOLOGICAL
IFGopPreCG
SMGpSTG
FusiGITG
InsuladStr
PPC
RISKGENES
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
CostofDyslexia
Risks
Dyslexia
POOROUTCOME: ReadingComprehension,EducationalAttainment,PsychosocialAdjustment
DLPFC
ORTHOGRAPHIC
PHONOLOGICAL
IFGopPreCG
SMGpSTG
FusiGITG
InsuladStr
PPC
RISKGENES
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
CostofDyslexiaisHigh
Developingdyslexia upto50%withfamilyhistory,(4timeshigher)
Costtoindividual >£100klessearning($150k)Costto(UK)society >£1bn/year($1.5bn)HighSchooldropout 2.5xPrisonpopulation 32-46%(notelowIQandnotSLD!)Anxietydisorder 2.0x(5.0xseveretestanxiety)Depression 2.0xSubstanceabuse 2.7xADHD 4.5x
Snowling etal.Psychol Bull2016;Pennington&Lefly.ChildDevelop2001;Cosden JLD2001;Wilsonetal.JLD2009;ForesightMentalCapitalandWellbeingProject.2008;DuPaul etal.JLD2012
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
CostofDyslexiaisHigh
Developingdyslexia upto50%withfamilyhistory,(4timeshigher)
Costtoindividual >£100klessearning($150k)Costto(UK)society >£1bn/year($1.5bn)HighSchooldropout 2.5xPrisonpopulation 32-46%(notelowIQandnotSLD!)Anxietydisorder 2.0x(5.0xseveretestanxiety)Depression 2.0xSubstanceabuse 2.7xADHD 4.5x
Snowling etal.Psychol Bull2016;Pennington&Lefly.ChildDevelop2001;Cosden JLD2001;Wilsonetal.JLD2009;ForesightMentalCapitalandWellbeingProject.2008;DuPaul etal.JLD2012
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
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LatestThinkingontheFactorsthatContributetoDyslexia:MultipleFactorsImpactDyslexia
NeurobioRisk2
NeurobioRisk1
NeurobioProtective1
NeurobioProtective2
DyslexiaRisk
EnvironmentRisk1
EnvironmentProtective1
Multipledeficitmodel: Pennington.Cognition‘06.Penningtonetal.JAbnorm Psychol ‘12Diathesis-stressmodel: Rosenthaled.“TheGenain Quadruplets”‘64Liabilitythresholdmodel: Gottesman &Shields.PNAS‘67
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
CumulativeRisk&ProtectionModelofDyslexia
ImportanceofanIntegrativeApproach toMaximizingChildren’sLearningPotential
Maximizing children’s learning potential
NEUROBIOLOGY
EXTERNALENVIRONMENT
INTERNALENVIRONMENT
STEREOTYPETHREATMOTIVATION&MINDSETRESILIENCE&GRIT
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
TODAY’STOPIC:CognitiveandSocio-EmotionalResilienceinDyslexia
Maximizing children’s learning potential
NEUROBIOLOGY
EXTERNALENVIRONMENT
INTERNALENVIRONMENT
STEREOTYPETHREATMOTIVATION&MINDSETRESILIENCE&GRIT
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Weaknesses vs. Relativestrengths
Risk vs. Protectivefactors
Vulnerability vs. Resilience
Outline• BACKGROUND
– Dyslexiacostlyinmanydimensions– Importanceofanintegrativeapproach
• TODAY’SFOCUS– Theresilienceframeworkofdyslexia– Cognitiveresilience– Socio-Emotionalresilience
• CONCLUSION,OTHERWORK(e.g.EnglishLearners)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Resilience
Theabilitytoadapttostressorsintheenvironment(adversity)by“bending”but
not“breaking”(Karatsoreos &McEwenF1000PrimeReports2013)
Socio-emotionalresilience Cognitiveresilience
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
ResilienceFrameworkofDyslexia:PromotingResilience&OptimizingDyslexiaOutcome
Risks
Dyslexia
PoorFunctionalOutcome• PoorReadingComprehension• NegativePsychosocialAdjustment
Haft,Myers,Hoeft.Curr Opin Beh Sci 2016
StephanieHaft
Socio-EmotionalProtect.F.
INTERNAL• Growthmindset• Hopefulthinking• Senseofcoherence• Locusofcontrol• SelfdeterminationFAMILY• Familycohesion• Maternalaffect• Strongparental
attachment• Parentalsupport&
understandingofRDPEER/SCHOOL• Peerrelationships• Mentorshipby
teachers• Teachersupport• Smallclass-size
CognitiveProtectiveFactors
• Orallanguageskills• Motorskills• Task-focusedbehavior• Executivefunctions• Interpersonal
relationships
LessSevereDyslexia
• Morphologicalawareness• Vocabulary• Verbalreasoning• Executivefunctions• Grammar
PositiveOutcome
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
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TheNeuroscienceofDyslexia– TraditionalViewFocusonWeaknesses,Risks&Vulnerability
phonologicalprocessing
(visual/selective)attention
cognitiveimplicitprocedurallearning
short-termmemory
informationprocessing
RELATIVEWEAKNESSES
d
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
TheNeuroscienceofDyslexia– TraditionalViewFocusonWeaknesses,Risks&Vulnerability
Occipito-Temporal(OT)Orthographicprocessing
Temporo-Parietal(TP)Phonologicalprocessing
POORREADERS&DYSLEXIA.Reducedefficiencyinbrainnetworksrelatedtospeech&visualaspectsofreading.Shaywitz etal.NEJM’98;Hoeftetal.JNeurosci ‘06.Hoeftetal.PNAS‘07
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
charactertraits,socio-emotional
Grit,Resilience,Mindset,Empathy
TheNeuroscienceofDyslexia– EmergingViewFocusAlsoonStrengths,ProtectiveFactors&Resilience
visuo-spatialHolistic,3d
cognitiveexplicitmemorycomprehension
IQ,reasoning,orallanguage…
RELATIVESTRENGTHS phonologicalprocessing
(visual/selective)attention
cognitiveimplicitprocedurallearning
short-termmemory
informationprocessing
RELATIVEWEAKNESSES
d
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
TheNeuroscienceofDyslexia– EmergingViewFocusAlsoonStrengths,ProtectiveFactors&Resilience
Occipito-Temporal(OT)Orthographicprocessing
Temporo-Parietal(TP)Phonologicalprocessing
PROTECTIVEFACTORS&RESILIENCEWhichbrainsystems???Whatmechanism???
Coincidence.Bryden MP.Laterality’87
Compensatory.LansdellHJ.CompPhysio Psychol ‘69,LevyJ.Nature’69
Causal.Kosslyn SM.PsycholRev’87,Cai etal.PNAS’13.
EvolutionaryadvantageGeschwind N.AnnalsofDyslexia‘84
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Outline• BACKGROUND
– Dyslexiacostlyinmanydimensions– Importanceofanintegrativeapproach
(Geschwind Lecture2014)
• TODAY’SFOCUS– Theresilienceframeworkofdyslexia– Cognitiveresilience– Socio-Emotionalresilience
• CONCLUSION,OTHERWORK(e.g.EnglishLearners)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
ResilienceFrameworkofDyslexia:COGNITIVERESILIENCE
Risks
Dyslexia
PoorFunctionalOutcome• PoorReadingComprehension• NegativePsychosocialAdjustment
Haft,Myers,Hoeft.Curr Opin Beh Sci 2016
CognitiveProtectiveFactors
• Orallanguageskills• Motorskills• Task-focusedbehavior• Executivefunctions• Interpersonal
relationships
LessSevereDyslexia
• Morphologicalawareness• Vocabulary• Verbalreasoning• Executivefunctions• Grammar
PositiveOutcome
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
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COGNITIVERESILIENCEResilientDyslexics
RESILIENTREADERS:Thosewithgoodcomprehensiondespitepoordecoding.
Thosewithdecodingdifficultiesrelymoreoncontextualinformationtobeabletoreadsuccessfully.INTERACTIVECOMPENSATORYMODELOFDYSLEXIA(Stanovich,1980)
Implicationsforintervention.
SmadarPatael PhD
LaurieCuttingPhD
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
COGNITIVERESILIENCEBrainMechanism?
RESILIENTREADERS
POORREADERS
TYPICALREADERS
Expectedpatternrelatedto:RESILIENCE
DECODING
COMPREHENSION
Decoding
Comprehension
TYPICALREADERS
GoodcomprehensionbutgooddecodingalsoPOOR
READERSPoordecodingbut
alsopoorcomprehension
RESILIENTREADERS
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
COGNITIVERESILIENCELeftDorsolateralPrefrontalCortex(DLPFC)
Resilient > Poor readersResilient > Typical readers
RESILIENT READERS
POOR READERS
TYPICAL READERS
RESILIENCE
DECODING
COMPREHENSION
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
COGNITIVERESILIENCENotjustdyslexicsbutanyonecanhaveit.
R²=0.12409
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
-40 -20 0 20 40
PrefrontalVolum
e
CognitiveResilience
10-16yochildrenwith&withoutpoordecoding
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
COGNITIVERESILIENCEChickenoregg?ShowsignsBEFOREreadingfailure.
R²=0.12409
R²=0.14004
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
-40 -20 0 20 40
PrefrontalVolum
e
CognitiveResilience
Prereading kids’leftDLPFCpredictsfuture‘resilience’
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
COGNITIVERESILIENCERoleofDLPFCNetwork?
-2
0
2
4
6work
working1backmemory
wm2back
loadencoded
maintenance
oddball
salient
shifting
attention
distractorcues
congruentexecutive
rulerehearsalconflictincongruentmonitoringrules
verbalverb
visuospatial
spatially
dyslexia
reading
readers
phonology
phonologicalphonetic
semanticsemantically
nounsnoun
1000FunctionalConnectome.Neurosynth.org
Relatedtolearning,attention,&cognitiveflexibility
Fronto-parietalnetwork
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
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COGNITIVERESILIENCEFronto-parietalnetwork“flexiblelearninghub”.
Dynamically changes how it connects to other key networks based on current goals.
Critical for learning new skills and building mental rules.
Allows immediate & flexible transfer of skills.
Coleetal.NatNeuroscience’13
Patael etal.underreview
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
COGNITIVERESILIENCE:Summary
• Prefrontal&fronto-parietalnetwork
• Cognitiveflexibility,learningnetwork
• Relatedstudiesalsopointtoprefrontalmechanisms
• Maysuggestimportanceofpromotingactivitiestoenhancecognitiveflexibility&self-regulationearly
Patael etal.underrev;Hoeft etal.PNAS’07&PNAS’11;HancockRichlan Hoeft.Neurosci Beh Rev‘16
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Outline• BACKGROUND
– Dyslexiacostlyinmanydimensions– Importanceofanintegrativeapproach
• TODAY’SFOCUS– Theresilienceframeworkofdyslexia– Cognitiveresilience– Socio-Emotionalresilience
• CONCLUSION,OTHERWORK(e.g.EnglishLearners)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
ResilienceModelofLD:SOCIO-EMOTIONALRESILIENCE
Risks
Dyslexia
PoorFunctionalOutcome• PoorReadingComprehension• NegativePsychosocialAdjustment
Haft,Myers,Hoeft.Curr Opin Beh Sci 2016
Socio-EmotionalProtect.F.
INTERNAL• Growthmindset• Hopefulthinking• Senseofcoherence• Locusofcontrol• SelfdeterminationFAMILY• Familycohesion• Maternalaffect• Strongparental
attachment• Parentalsupport&
understandingofRDPEER/SCHOOL• Peerrelationships• Mentorshipby
teachers• Teachersupport• Smallclass-size
PositiveOutcome
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCECharactertraitscriticalforsuccess
Grit(selfdiscipline),morepredictivethanIQ(2x)&aboveandbeyondachievementitself(Duckworth&Seligman,Psychol Sci ‘05)
2x
Above&beyondIQ&achievement
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEBrainmechanismsofGritvs.GrowthMindset
VTA
GROWTHMIND-SET:Beliefthatabilityiseffortbased
GROWTHMINDSETCOGNITIVEREAPPRAISAL(Dohertyetal.Science‘04)
INTRINSICMOTIVATION(Muyrayama etal.PNAS’10)
VTA
GRIT:Perseverancetowardalongtermgoal
GRITPERSISTENCE(Gusnard etal.PNAS‘03)
FUTUREREWARD(Dohertyetal.Science’04)
Myersetal.SCAN2016
Multipletargets– Multipleroutestoenhancelearning
ChelseaMyers
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
5/3/17
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SOCIO-EMOTIONALRESILIENCEStereotypeThreatputsIndividualsAtRiskforLearning
“Stereotypethreatisbeingatriskofconfirming,asself-characteristic,anegativestereotypeaboutone’s
group.”–SteeleandAronson(1995)
“Whitemencan’tjump.” “Womenarenotgoodatmath.”
reducingstereotypethreat.org,Whistlingvivaldi byClaudeSteeleBackground|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
“AfricanAmericanshavelowerintelligencethantheirwhitepeers.”
“AfricanAmericansarenotsmart.”
SOCIO-EMOTIONALRESILIENCEStereotypethreatMAYexistinLDs
Whymightindividualswithlearningdisabilities(includingdyslexics,butalsoADHDetc)experiencestereotypethreat?
• Groupidentification- lowachievement• Awareofstereotype(KellyandNorwich,2004;Rashkind etal.,2006)• Negativeacademicself-concept(Zeleke,2004)• Lowself-esteem,negativeaffect,anxiety,and
depressionwhenfacedwithperformance-avoidancegoals(thedesiretoperformlesspoorlythanothers)(Sideridis,2007;Aquino,2011)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEAnIntegratedProcessModelofStereotypeThreat
ConceptofAbilityDomain
ConceptofGroup
ConceptofSelf
“Iamagirl…”
“IthinkIamgoodatmath…”
“Girlsarebadatmath(andmathisimportanttome)…”
Forbesetal.,2008Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEAnIntegratedProcessModelofStereotypeThreat
ConceptofAbilityDomain
ConceptofGroup
ConceptofSelf
“Iamagirl…”
“IthinkIamgoodatmath…”
“Girlsarebadatmath(andmathisimportanttome)…”
Forbesetal.,2008
Discordanceleadstostereotypethreat
ReducedattentionStress&AnxietyFear&ThreatReducedlearning&memory,&performance
Everyoneisprone.
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEBrainmechanismofstereotypethreat?
Women&under-performanceinmath
Krendl etal.Psychol Sci 2008
LackofimprovementinmathperformanceovertimeunderST(interaction:p<.005)
Stereotypethreatimpactskeycognitivenetworksandemotion-relatednetworksnegatively
LackofMATHrelatedactivationunderST
IncreaseinEMOTIONalresponseunderST
NoSTgroup STgroup NoSTgroup STgroup
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEBuildingResilienceAgainstStereotypeThreat
• Reframingthetask(e.g.Quinn&Spencer,2001)
• De-emphasizingthreatenedsocialidentities(e.g.Stricker andWard,2004)
• Rolemodels(e.g.Blantonetal.,2000)
• Externalattributionsfordifficulty(e.g.Goodetal,2003)
• Self-affirmations(e.g.Schimel etal.,2004)
• Growthmindset(e.g.Aronsonetal.,2002)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
5/3/17
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SOCIO-EMOTIONALRESILIENCEStrength-basedapproachmaybuildresilience
vonKárolyi etal.,‘01;‘03;Diehl…Hoeft…Pugh.NeuroImage ‘14
Visuo-spatialprocessingshowyin-yangrelationshipwithreading
KenPugh
reading
visuo-spatial
r=0.42p<0.05
BEHAVIOR
dyslexics non-dyslexics
BRAIN
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEMentoringmaybuildresilience
Scores
26.7%***P<0.0001
12.5%~*P=0.05
2.5
3
3.5
4
4.5
5
Responsetofailure
Depression SelfEsteem
Fall Spring
Displaymorepositiveemotionsandeffort-basedstrategiesinthefaceoffailure.
IMPROVEMENTIN:
SELFESTEEM(12%)GRIT(value)(8-36%)GROWTHMINDSET(14%)LDIDENTITY(comfort,bond,importance)(24-52%)READINGSELF-CONCEPT(19%)etc…
N=48
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCEMentoringmaybuildresilience
-100
-50
0
50
100
150
1.5 2 2.5 3 3.5
Self-Esteem
(FalltoSprin
g%increase)
Mentee-RatedMentorshipQuality(1-lowto3-high) N=39
R2=0.13(r=0.36)P=0.025
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SOCIO-EMOTIONALRESILIENCE:PositiveImpacton Learning-RelatedBrainRegions
Haft,Black.Underprep
Medial/LateralPrefrontalCortex(m/lPFC):information
processing
DorsalAnteriorCingulateCortex(dACC):reward-baseddecisionmaking;errormonitoring
Amygdala,Hippocampus:fear,emotions,andfearlearning
Hypothalamus,PituitaryGland:regulation&productionofhormones
(e.g.cortisol)
Self-Awareness Self-Concept
Self-Determination
Regulatesemotionalresponsetothreat.
SocialSupport
Regulateshormones.Reducesstress. Positive
Emotion Coping
Influencesneuroendocrineresponsesto
stress
Self-Esteem
Modulatessalienceofinformation.
Mindset
Influencesadaptiveresponsestoerrors.
SOCIO-EMOTIONALRESILIENCE:Summary
• Socio-emotionalcharactertraitsimpactlearningrelatedbrainmechanisms.
• Largeindividualdifferences.Understandingthesedifferencesareimportant(LearnerPositionalSystem[LPS]).Opportunityforpersonalizedlearning.
• Stereotypethreatmayexistthatimpedeonlearningbutcanbeminimizedintheclassroom.
• Potentialfortakingastrength-basedapproach.• Mentoringpotentiallybuildsresilience.
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Outline• BACKGROUND
– Dyslexiacostlyinmanydimensions– Importanceofanintegrativeapproach
• TODAY’SFOCUS– Theresilienceframeworkofdyslexia– Cognitiveresilience– Socio-Emotionalresilience
• CONCLUSION,OTHERWORK(e.g.EnglishLearners)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
5/3/17
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CONCLUSION:PromotingResilience
Risks
Dyslexia
PoorFunctionalOutcome• PoorReadingComprehension• NegativePsychosocialAdjustment
Haft,Myers,Hoeft.Curr Opin Beh Sci 2016
Socio-EmotionalProtectiveFactors
CognitiveProtectiveFactors
LessSevereDyslexia
PositiveOutcome
CONCLUSION:PromotingResilience
Risks
Dyslexia
PoorFunctionalOutcome• PoorReadingComprehension• NegativePsychosocialAdjustment
Haft,Myers,Hoeft.Curr Opin Beh Sci 2016
Socio-EmotionalProtectiveFactors
CognitiveProtectiveFactors
LessSevereDyslexia
PositiveOutcome
COGNITIVETRAINING
RESILIENCEBUILDING(mentoring)
LITERACYINTER-VENTIONS
CONCLUSION:BuildingResilience
• Scaffoldforpositivereframing>Cognitivereappraisal,Senseofcontrol,Cognitivecontrol&self-regulation>Growthmindset,Motivation,Grit
• Strengthbasedapproach>Confidence,Optimism,Motivation
• Socialsupport,rolemodel,mentoring>Connectiontocommunity
• Reducestereotypethreat>Optimizelearningenvironment&enhancedperformance
• Stressinoculation(exposuretotolerablelevelsofstress&challenges)
Charney.NatRevNeurosci 2009;KenGinsberghttp://www.fosteringresilience.com/7cs.phpBackground|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
BasicPlatform
Onlinetool Resilience,Motivation,Self-Esteemetc
ResourceguideIndividual|Schools
Newtool2Negativitybiasimpactonlearning
Newtool1ReadingAnxiety
ReportIndividual|Schools
Newtool3Neurosciencetool
2016 2017
R&D
R&D
R&D
R&D
R&D
R&D
ServerDashboard
Validation
Limitedrelease
Validation
Validation
Validation
Limitedrelease
Limitedrelease
Limitedrelease
Limitedrelease
Limitedrelease
2018
1M
SELTOOLKITR&DTIMELINE(PENDINGFUNDING)
Newtool4Computerizedtrainingtooltoenhancelearning
R&D Validation Limitedrelease
2019
2M
SELTOOLKIT(basic)
SELTOOLKIT(plus)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Canwehelpourchildrenbecomemoreresilient?
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
(OTHER)WORK@
ProtectivefactorsBuildingresilience
Earlyidentification&prevention
Mechanismsofdyslexia,reading&
learning
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Community
5/3/17
10
WANTED!Part-timelicensedclinicalpsychologist
CommunitypartnersPhilanthropicpartners
FumikoHoeft MDPhD,Exective Director
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
MissionandGoals
WHOWEAREAnewandcross-disciplinary‘PrecisionEd-Health’centeracrossthe(6)UCcampuseswithexpertisein(bilingual)education,sp-ed,cogpsych,neuroscience,medicine,&policy.
PrecisionMedicineisanemergingdata-drivenapproachfordiseasetreatmentandpreventionthattakesintoaccountindividualvariabilityinenvironment,lifestyleandgenesforeachperson.(2015)PrecisionEd-Healthisandata-drivenapproachtopreventthespiraleffectofpooreducationalattainmenttohealthdisparitytakingintoaccountvariabilityineachchildbylookingatlargeamountsofdatafromtheenvironment,psychological,cognitive,neuroscience,biomedicalinformation.
MISSION.Tackleissuesassociatedwitheducationandhealthdisparitywithaparticularemphasisonunderrepresentedpopulations.
LONG-TERMGOAL.ToprovidethebesteducationalandhealthoutcomesforALLCHILDRENregardlessoftheirbackground.
SHORTTERMGOAL.Earlyidentificationandinterventionofchildrenatriskforlearningchallenges,especiallyinEnglishlearners.
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
SchoolReadiness&PersonalizedLearningApp.Modules
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
BasicPlatform
DyslexiaScreenerLiteracy
SchoolReadiness(Basic)Literacy|Cognition
SchoolReadiness(Premium)Literacy|Cognition|Math|SEL|Motor
DyslexiaPhenotypeLiteracy| Cognition++
ADHDScreenerCognition+
LearningStyleLiteracy|Cognition|Math|SEL|Motor
2017 2018
Development
Development
Development
Development
Development
Development
BackendInterface
Validation
Validation
Validation
Validation
Validation
Validation
Norming
Norming
Norming
Norming
Norming
Norming
2019
2M
4M
SCHOOLREADINESSANDPERSONALIZEDLEARNINGAPPPRODUCTIONTIMELINE(PENDINGFUNDING)
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
STARModel@SILC
SILCSTAR
SERVICESe.g.PD
TRAINING(Multidisciplinary)
ADVOCACY
RESEARCH
BACKGROUND:Education&HealthDisparityinEnglishLearners(ELs)
ELsare200%morelikelytoliveinpoverty
LowEnglishProficiency
DifficulttoPredictLearningChallenges
PoorEducationalAttainment
LowIncome
PoorHealth
9.3%
22.3%
US(1in10) CA(1in4)
ProportionofELsinPublicSchool
33.3%66.7%
1in3inCA 2in3inOtherStates
DistributionofELswithintheUSVICIOUSCYCLEOF
INEQUALITY
70.0%
30.0%
SpanishEL OtherEL
NativeLanguages Approx 400spokeninUS!
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
5/3/17
11
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
TranslationalResearchProgram
Best(Eng+Sp)
ExistingResearch-
based(mA2i)
Current(Eng)
NewResearch(Non-
language–Aud,Fam)
HealthOutcome
Biological/EnvironmentRiskFactors
1.IDENTIFYBESTWAYTOPREDICTFUTURELEARNINGCHALLENGESEARLYANDACCURATELY.(LearnerPositionalSystem[LPS])
2.INDIVIDUALIZEINSTRUCTION/INTERVENTION.Computerizedtrainingprograms,e.g.mA2i,GraphoGame
3.EVALUATEHEALTHOUTCOME.Obesity,Immunefunction,Telomerese,etc…
4.EVALUATEIMPACTOFENVIRONMENT.e.g.toxin
CENTERofINNOVATIONINNEUROSCIENCE-BASED
TECHNOLOGYFOREEUCATIONANDLEARNING
UCSF|UCBerkeley|Stanford
adam bruce fumiko
joaquin jyoti melina
miriam roeland silvia
Science of Learning Collaborative Network (SL-CN)UCSF - Stanford - UC Berkeley
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
BayAreaUCSF(NCWhite,RHendren,KLeWinn,LPasch,MGorno-Tempini,BMiller);UCBerkeley(SBunge);UCDavis(YUchikoshi,DAmaral,CWuNordahl);UofSF(GLeung);USA/CanadaBostonCollege(JBlack);GeorgiaStateU(RMorris);HarvardU,BostonChildren’sHospital(LProck Albers);MIT(JGabrieli);UofBritishColumbia(LSiegel);UofMichigan(IKovelman,RMarks);VanderbiltU(LCutting);
YaleU,HaskinsLabs,UConn(KPugh,JReuckl;EGrigorenko);AsiaBeijingNormalU,China(HShu);HebrewU,Israel(RFrost);KeioU,Tokyo,Japan(BYamagata,MMimura);Nat’lCntrl U,InstofCogNeurosci,Taiwan(DWu,OTseng)UHongKong,China(CMcBride);EuropeBCBL,Spain(MCarreiras);UCollegeLondon,UK(CHulme);UofJyvaskyla,Finland(HLyytinen,PLeppannen,URichardson);UofSalzburg,Austria(FRichlan);
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
Thankyou…[email protected] |@fumikohoeft |profies.ucsf.edu/fumiko.hoeft
Thankyou…
Background|ResilienceFramework|CognitiveResilience|Socio-EmotionalResilience|Conclusion
[email protected] |@fumikohoeft |profies.ucsf.edu/fumiko.hoeft