Pusa Road, New Delhi - 110005 (India). www.blkhospital.com

BLK Super Speciality Hospital

24-Hour Helpline: 011-30403040

BLK Centre forBone Marrow Transplant

The Centre is equipped with ultra-modern infrastruc-

ture and internationally trained, widely experienced

faculty. It is supported by state-of-the-art laboratory & transfusion services,

along with a fully equipped Radiation Oncology unit, with facility for total

body irradiation.

The Centre is the ‘first’ in New Delhi to establish and successfully perform

‘Unrelated Donor Stem Cell Transplant’ for Thalassemia Major using donor

from Indian registry. The Centre is also an authorised stem cell collection

centre for DATRI Blood Stem Cell Donor’s Registry.

Our Centre

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BLK Centre for Bone Marrow Transplant provides

high-quality specialised patient care in a setting of

education and research. Our dedicated team embraces

the values of initiative, innovation, collaboration,

confidentiality, empathy, integrity and are focussed on

providing non-intrusive, patient-centric quality care.

Our aim is to provide safe and effective technologies

to all the patients; to continually monitor our

methods to ensure clinical excellence at all times; to

assess all patient concerns including clinical,

psychological and financial ones; and to perform

constant audits on all aspects of care that influence

patient outcomes and satisfaction.

The BLK Centre for Bone Marrow Transplant is part

of BLK Super Speciality Hospital − one of India’s

largest, private sector, tertiary care hospitals. Established in early 2010, the

Centre’s aim is to provide patients with incurable blood disorders the option

of transplant as a possible cure. BLK’s team has a combined experience of

1300 transplants. More than 1100 transplants have been performed within a

short span of 8 years, with a success rate at par with the world’s best.

The Centre receives transplant patients not only from India, but also from

countries like Iraq, Pakistan, Bangladesh, Afghanistan, Nigeria, Kenya,

Sudan, United Arab Emirates, Uzbekistan and Nepal. Today, more than 50%

of the patients arrive from different parts of the world.

Introduction

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More than 125 specialists, nurses and technicians work together to plan and

implement treatment designed to meet the individual needs of each patient.

The best in high-quality treatment, access to the latest technology and

research, and our all-encompassing “Patients First” philosophy make us the

leading centre in Asia.

24 bedded state-of-the-art unit, one of the biggest centres of its kind

across Asia and one of the largest in the world

The centre has performed the maximum number of transplants in

North India

Large spacious transplant suite room with HEPA filter and positive

pressure ventilation

Medical and Paediatric intensive care unit with isolation beds

Day care facility for outpatient Chemotherapy / Immunotherapy /

Blood Transfusion

Available Facilities

BLK Centre for Bone Marrow Transplant provides comprehensive

interdisciplinary care to its patients through its world-class facilities and

internationally trained experts. Key features of the Centre include:

Department of Transfusion Medicine

Round-the-clock service for blood components including platelet apheresis

NAT tested blood components

Stem cell unit for peripheral stem cell harvesting and bone marrow processing

Gamma Irradiator

Laboratory Services

Haematology and Flow Cytometry

HLA and Molecular Laboratory

Microbiology

Therapeutic Drug Assays

Histopathology

BLK Centre for Bone Marrow

Transplant was started as a 2-bed unit

and is today, a full- fledged 24-bedded facility. The Centre is reckoned as one of the

largest units in the world and the biggest in Asia. Credited with the maximum

number of Bone Marrow Transplants in India, the Centre diagnoses and treats a

A Full Service Offering

Endoscopy / Bronchoscopy / Dialysis unit

Transplants for all age groups – Infants, Child, Adult and Elderly

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Stem Cell Collection:

Peripheral blood stem cells are

collected in a process called

Apheresis. This is performed

in the therapeutic Apheresis

out patient unit in Transfusion Medicine department. The specially trained nurses

supervised by Transfusion Medicine physician in this unit perform more than 125

Apheresis procedures a year.

Bone Marrow Harvest: The Centre has performed these procedures since its

inception. A Bone Marrow Harvest is done as an in-patient surgical procedure,

with the patient under general anaesthesia. A small portion of bone marrow - the

soft, spongy substance that fills the inner cavities of bones and produces blood is

collected for transplantation, using a needle that passes through the skin and into

the marrow cavity of the hip bone.

Autologous Transplantation: An Autologous Transplant involves high-dose

Chemotherapy followed by infusion of the patient’s own previously collected

peripheral blood stem cells or bone marrow. The Chemotherapy treatments are

given to eliminate cancer cells in the body. Infusion of new marrow or peripheral

blood stem cells replaces the marrow destroyed by Chemotherapy and/or

Radiation Therapy.

Allogeneic Transplantation: An Allogeneic Transplant involves high-dose

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Autologous (self-donated) transplants

Allogeneic (donor) transplants using matched sibling donors

Allogeneic transplants using unrelated donors

Allogeneic transplants using Haploidentical (half-matched) donors

Allogeneic transplants using umbilical cord blood

Myeloablative conditioning Allogeneic transplants

Reduced-intensity conditioning Allogeneic transplants

Understanding the Technical Aspects of Blood and Bone Marrow Transplantation

wide variety of blood disorders and blood cancers, such as all kinds of Anaemia,

Marrow Failure Syndromes, Coagulation Disorders, Acute and Chronic Leukaemia,

Myelomas, Lymphomas and Myeloproliferative & Lymphoproliferative Disorders,

Hodgkin’s and Non-Hodgkin’s Lymphoma, Multiple Myeloma including

Amyloidosis, Myelodysplastic and Myeloproliferative Syndromes (including

Myelofibrosis), Aplastic Anaemia, Sickle Cell disease, Germ Cell Tumours, other

Solid Tumours such as Paediatric, Sarcomas and Paediatric Central Nervous System

Tumours, Paediatric diseases such as inherited metabolic and genetic diseases.

The Centre offers a range of facilities and services which include both

Allogeneic and Autologous transplant using bone marrow, peripheral blood stem

cells and cord blood stem cells for various benign and malignant disorders. The

following types of transplants are performed at the Centre:

Our patient outcomes are consistently as

good as or better than national benchmarks.

In the last 5 years the day+100 survival after Autologous Stem Cell Transplant was

97% for multiple Myeloma and 90% for Lymphoma. In the case for Allogeneic Stem

Cell Transplant it was 90% for Thalassemia Major (Thalassemia Free Survival-82%),

78% for Aplastic Anaemia and 70% for Leukaemia.

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Program Outcomes

BLK Centre for Bone Marrow

Transplant regularly conducts

innovative, ground-breaking research in the field of blood and marrow

transplantation. The Centre has published numerous scientific papers in various

index national and international journals and has also presented them in many

international conferences. Our goal is to provide research trials for most clinical

situations as per the needs of our patients.

Our record shows our commitment to reduce transplant toxicities and improve

patient outcomes. We perform sponsored research protocols, as well as our own

authored protocols. We investigate new mobilizing agents for the collection of

peripheral stem cells and perform numerous research activities intended to

improve the management of acute and chronic graft versus-host disease and other

toxicities associated with transplantation. The Centre also collaborates nationally

on clinical trials to advance the science of transplantation.

Chemotherapy and / or Radiation Therapy, followed by infusion of donor bone

marrow or peripheral blood stem cells. The marrow or stem cells come from an

appropriately HLA (immune)-matched related or unrelated donor.

Umbilical Cord Blood Transplantation: For patients without a related or

unrelated donor, publicly banked umbilical cord blood can be used to perform

Allogeneic Transplantation. One or two umbilical cord blood units are used to

provide blood stem cells for bone marrow recovery after Chemotherapy and/ or

Radiation Therapy.

Haploidentical Donor Transplantation: This procedure uses HLA

half-matched (haplotype) donors such as biological parents, children or

half-matched siblings for Allogeneic Transplantation. The ability to use

haploidentical donors is of special relevance to patients who do not have

HLA-matched sibling or unrelated donor options.

Reduced Intensity Transplantation: These Allogeneic Transplants uses

smaller doses of Chemotherapy and / or Radiation Therapy. This treatment option

is for patients who may not be able to tolerate a full-intensity or Myeloablative

Allogeneic Transplant (for example, older patients or those with multiple medical

issues).

Commitment to Research

Where passion meets healing

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