Biosafety Status and Prospects of Agricultural BiotechnologyKlaus Ammann, Guest ProfessorDelft University of Technology, Netherlands

Biosafety Status and Prospects

Literature citation, forSlideshows and Manuscripts

Web of Science, all databases

Web of Science, all databases

Web of Knowledge, analytical tools and websites

Web of Knowledge, analytical tools and websites

Web of Knowledge search mode

Search mode „biofuel“ in Topic

Search result: 2282 references

Web of Knowledge, results

Endnote 10 directories of .enl databasesEndnote library, part of directory

Endnote library, detailsEndnote library, details

Endnote library, contents, section of transgenic Poplars

Endnote library, contents, GM poplars

EBZ Regensburg

EBZ Regensburg

Trends in Genetics free for EZB participants

Trends in Genetics free for EZB participants

Gatehouse The Case of the Monarch butterfly full access with VPN

Gatehouse The Case of the Monarch butterfly full access to pdfWith VPN (Virtual Private Networking) and IP of University of Bern on Laptop

Gatehouse The Case of the Monarch butterfly, no access without VPN

Gatehouse The Case of the Monarch butterfly, no access without VPN (Virtual Private Networking)

Gatehouse, A.M.R., Ferry, N., & Raemaekers, R.J.M. (2002)The case of the monarch butterfly: a verdict is returned. Trends in Genetics, 18, 5, pp 249-251 http://www.botanischergarten.ch/Bt/Gatehouse-Case-Monarch-2002.pdf

Gatehouse pdf document

Upload of pdf files to Bern server www.botanischergarten.ch

Upload of pdf files to Bern server

Palm Desktop Memo: list of links, poplar, biofuel

Palm Desktop links poplar biofuel

Endnote library, contents, section of transgenic Poplars

Endnote library, contents, GM poplars

Manuscript citations with authors in text

Manuscript citations with numbers

Literature alphabetic, with links to pdf

Literature alphabetic, with links to pdf

Literature numbered, without links to pdf

Literature numbered, without links to pdfs

Effects Publication

Werner Arber, Nobel Laureate 1978:

Interestingly, naturally occurring molecular evolution,i.e. the spontaneous generation of genetic variants hasbeen seen to follow exactly the same three strategies as those used in genetic engineering14. These three strategies are: (a) small local changes in the nucleotide sequences,(b) internal reshuffling of genomic DNA segments, and(c) acquisition of usually rather small segments of DNA

from another type of organism by horizontal gene transfer.

Arber, W. (2002) Roots, strategies and prospects of functional genomics. Current Science, 83, 7, pp 826-828 http://www.botanischergarten.ch/Mutations/Arber-Comparison-2002.pdf

Arber, W. (2002) Roots, strategies and prospects of functional genomics. Current Science, 83, 7, pp 826-828 http://www.botanischergarten.ch/Mutations/Arber-Comparison-2002.pdf

Arber

However, there is a principal difference between the procedures of genetic engineering and those serving in nature for biological evolution. While the genetic engineer pre-reflects his alteration and verifies its results, nature places its genetic variations more randomly and largely independent of an identified goal.

Arber, W. (2002) Roots, strategies and prospects of functional genomics. Current Science, 83, 7, pp 826-828 http://www.botanischergarten.ch/Mutations/Arber-Comparison-2002.pdf

Arber, W. (2002) Roots, strategies and prospects of functional genomics. Current Science, 83, 7, pp 826-828 http://www.botanischergarten.ch/Mutations/Arber-Comparison-2002.pdf

Arber

Bau

do

, M

.M.,

Lyo

ns,

R.,

Po

wer

s, S

., P

asto

ri,

G.M

., E

dw

ard

s, K

.J.,

Ho

ldsw

ort

h,

M.J

., &

Sh

ewry

, P

.R.

(200

6)T

rans

gene

sis

Has

Les

s Im

pact

on

the

Tra

nscr

ipto

me

of W

heat

Gra

in T

han

Con

vent

iona

l Bre

edin

g. P

lant

B

iote

chno

logy

Jou

rnal

, 4,

4,

pp

369-

380

http

://w

ww

.bot

anis

cher

gart

en.c

h/O

rgan

ic/B

audo

-Im

pact

-200

6.pd

f

Sh

ew

ry,

P.R

. &

Jo

ne

s,

H.D

. (2

00

5)

Tra

nsg

en

ic W

he

at:

Wh

ere

Do

We

Sta

nd

aft

er

the

Firs

t 1

2 Y

ea

rs?

An

na

ls o

f A

pp

lied

Bio

log

y, 1

47

, 1

, p

p

1-1

4

htt

p:/

/ww

w.b

ota

nis

che

rga

rte

n.c

h/O

rga

nic

/Sh

ew

ry-P

erf

orm

an

ce-2

00

6.p

df

Baudo: comparison in genomic disturbance: GM crops are less disturbed (black dots) than classic breeds

Scatter plot representation of transcriptome comparisons, Baudo et al. 2006transgenic vs. controlendosperm 14 dpa

28 dpa 8 dpg

2 conventionallinesEndosperm14 dpa

28 dpa leaf at 8 dpg

transgenic vs. conventional Endosperm14 dpa

28 dpa leaf at 8 dpg

EU-Project Wider Fields, Ammann-Kovacovsky-2008Huesken, A., Ammann, K., Messeguer, J., Papa, R., Robson, P., Schiemann, J., G., S., Stamp, P., J., S., & Wilhelm, R. (2007)

A major European synthesis of data on pollen and seed mediated gene flow in maize in the SIGMEA project. In GMCC-07, Third International Conference on Coexistence between Genetically Modified (GM) and non-GM based Agricultural Supply Chains, Seville Spainhttp://www.botanischergarten.ch/SIGMEA/Huesken-Synthesis-2007.pdf

Wider Fields

Bilsborrow, P.E., Evans, E.J., Bowman, J., & Bland, B.F. (1998)

Contamination of edible double-low oilseed rape crops via pollen transfer from high erucic cultivars. Journal of the Science of Food and Agriculture, 76, 1, pp 17-22 http://www.botanischergarten.ch/Brassica/Bilsborrow-Contamination-Edible-1998.pdf

A real health problem,But not discussed,Since it does not Concern transgenic crops

Real health problem

Matsuoka, Y., Vigouroux, Y., Goodman, M.M., Sanchez, G.J., Buckler, E., & Doebley, J. (2002)A single domestication for maize shown by multilocus microsatellite genotyping. Proceedings of the National Academy of Sciences of the United States of America, 99, 9, pp 6080-6084 http://www.botanischergarten.ch/Bt/Matsuoka-Single-Domestication-2002.pdf

Phylogenesis Maize and

Teosinte

in the US maize yields have accelerated in the last ten yearsin the US maize yields have accelerated in the last ten years

• actual breeding plus cultural practice gain

Troyer, A.F. (2006)Adaptedness and Heterosis in Corn and Mule Hybrids. Crop Science, 46, 2, pp 528-543 http://crop.scijournals.org/cgi/content/abstract/cropsci;46/2/528 AND http://www.botanischergarten.ch/Bt/Troyer-Adaptedness-Heterosis-2006.pdf

corn yields in France and Italy in the corn yields in France and Italy in the

last 10 years fail to show the same trend last 10 years fail to show the same trend

0

20

40

60

80

100

120

1955 1960 1965 1970 1975 1980 1985 1990 1995 2000 2005 2010

10

0 k

g/h

a FranceItalyFrance 95-06Italy 95-06

http://epp.eurostat.ec.europa.eu/portal/page?_pageid=0,1136206,0_45570464&_dad=portal&_schema=PORTAL

Cattivelli, L., Rizza, F., Badeck, F.W., Mazzucotelli, E., Mastrangelo, A.M., Francia, E., Mare, C., Tondelli, A., & Stanca, A.M. (2008)

Drought tolerance improvement in crop plants: An integrated view from breeding to genomics. Field Crops Research, 105, pp 1-14 http://www.botanischergarten.ch/DroughtResistance/Cattivelli-Drought-Tolerance-2008.pdf

Cattivelli Drought Tolerance

Monocle