Bio 342Human

Physiology• Pick up an information form, complete

it, and turn it in before leaving.

A physiologist asks…

• How do things work in the human body?– How is stability achieved?– What are the causes and consequences of

disruptions of stability?– How can stability be restored?

• How do we know what’s going on inside the body?

• How have things come to be the way they are?

Theme of this course:

Homeostasis

First Demonstration for Bio 342 Human Physiology

• Listen carefully to the music and to how it is interpreted

• Observe the human body in action during the performance of the piece

• Consider the activity of cells, tissues, and organs in the musician

Physiology in Action!

Examples from the performance:

BIO 342 HUMAN PHYSIOLOGY

• PHYSIOLOGY: The study of the function of cells, tissues, organs, and organ systems.

• THE TEXT: Widmaier et al. 2008 (11th ed.)– Chapter 2-5 review of other

courses– Using your textbook

General Course Objectives

1. To develop a basic understanding of the principles of physiology, with an emphasis on homeostatic mechanisms and negative feedback control.

• 2. To develop an appreciation for the experimental basis of our knowledge of physiology.

• 3. To sharpen laboratory skills with exercises that require forethought, planning, and refinement.

General Course Objectives

• 4. To organize and analyze information so as to develop critical thinking skills.

• 5. To write concisely in the form of scientific abstracts.

• 6. To communicate effectively in oral form.

The Syllabus (on the course website

http://webs.wofford.edu/davisgr/bio342/)

• Office & home phone numbers

• E-mail (davisgr@wofford.edu)

• Lecture topics by week– Text chapters in parentheses– Read in advance of lectures

A Website for this Course!

• Check daily.

• Get Study Questions and Powerpoint files via the website.

LABORATORIES• 5-8 Computer setups, <22 persons per lab• 2:00 - 5:00 Mon (Davis) & Tues 8-11 • 2:30 – 5:30 Tue (Moeller) • 2:00 – 5:00 Wednesday (Nguyen)• 2:30 – 5:30 Thursday (Nguyen)• May shift topics due to availability of animals• 1 Lab Report in the form of abstracts

– very concise, based on lab data– Incorporate statistics– With revision and resubmission

• No separate lab tests; lecture tests include labs• This week’s Lab: Using live animals!

GRADING• 3 lecture tests = 60%

– multiple choice (choose all correct answers)– Some short answer– Rarely fill in the blank– Sometime create or complete graph or diagram– discussion question(s)

• Cumulative final exam = 20%• Other work = 20%

– Abstract = 10%– 1 Question Quizzes (1QQs) = 10%

Honor Code

• All worked is to be “pledged.”

• Issues of plagiarism to be handled by the Honor Court

ODDS AND ENDS

• NO FOOD or DRINKS in Lab • Possible limited lab swapping

– under special circumstance– students arrange paired swap– prior approval– See “Attendance” webpage

• BE ON TIME, READY TO GET TO WORK• DON’T ASK ABOUT LENGTH OF LAB• BE READY TO START ON TIME

Study Questions & Quizzes• Questions provided for each chapter

(On the website!)• Read the book and answer the questions

PRIOR to class meeting• Class time is used to deal with

problematical topics and reinforce the major concepts

• Be ready for 1QQs

Study Questions & Quizzes

• Rationale for this format:– Writing helps to consolidate memory and

recall– Greater effort results in better retention and

understanding– Students are not passive learners– Able to cover more information

Improve MCAT, DCAT and GRE scores

More stuff

• Be early or on time for lecture and lab

• Pay attention (no cell phones, email, Facebook, etc. during lecture or lab)

1st Assignment:Personal

Informationdue on Friday

Chapter 1 and parts of 16

• Tissues• Organs• Organ Systems• Homeostasis• Negative feedback• Two detailed examples: Thermoregulation

and Glucose Homeostasis

Genetics & Development

Cell & Molecular

200

Cell types

• Neuron• Hepatocyte• Cardiac myofiber• Septal cell (lung)• Purkinje fiber (heart)• Melanocyte• Enteroendocrine cell• Simple cuboidal cell

of the proximal renal tubule

• Basal cell of stratum germinativum (skin)

• Endothelial cell• Fibroblast• Osteocyte• Chondrocyte• Acinar cell of pancreas• Beta cell of Islet of

Langerhans• Schwann cell

More cell types

• Sertoli cell• Leydig cell• Hair cell (inner ear)• Smooth myofiber of

arteriole• Mast cell• Unilocular adipocyte• Osteoblast• Monocyte

• Langhan’s giant cell• Megakaryocyte• Satellite cell (ganglion)• Myofibroblast in capsule

of spleen• Odontoblast• Ameloblast• Myoepithelial cell of

salivary gland

Even More Cell Types

• Parietal cell

• Chief cell (stomach)

• Paneth cell

• Podocyte

• Juxtaglomerular cell

• Cell of the macula densa

• Chromaffin cell (adrenal medulla)

• Cell of the corona radiata

• Spermatogonia• Granulosa lutein cell• Secretory cell of the

zona glomerulosa• Secretory cell of the

zonal fasciculata

Histology

Figure 01.01cAnatomy

The Human Body:A Society of Cells

• Imagine you are a cell. Ask yourself:• How did I get here? • What do I do for myself? (What are my special characteristics and

functions?) • What do I do for the person in whom I reside? (What are my contributions

to the whole organism? To homeostasis?) • What do I need simply to survive?• What do the other cells provide for me that I cannot obtain alone?• What governs my actions? • How long will I live?• Can I be replaced? If so, how?• What would happen to the organism if I along with all the other cells of my

type were to fail to function properly?

Choose a cell type from list, have answers ready for class on Wednesday.

A physiologist asks…

• How do things work in the human body?– How is stability achieved?– What are the causes and consequences of

disruptions of stability?– How can stability be restored?

• How do we know what’s going on inside the body?

• How have things come to be the way they are?