Bio 342Human

Physiology

Theme of this course:

HomeostasisAging, infection, injury, disease Disturbed homeostasis

BIO 342 HUMAN PHYSIOLOGY

• PHYSIOLOGY: The study of the function of cells, tissues, organs, and organ systems.

• THE TEXT: Widmaier et al. 2011 (12th ed.) & 2014 (13th edition)– Chapter 2-5 review of other courses– Using your textbook– Using chapter questions from

Website

The Syllabus (on the course website

http://webs.wofford.edu/davisgr/bio342/)and Moodle Site for Grades and Electronic Assignments

• Office & cell phone numbers• E-mail (davisgr@wofford.edu)• Lecture topics by week

– Text chapters in parentheses– Read in advance of lectures– Check Moodle site 3x/wk at least

LABORATORIES• May shift topics due to availability of animals• One Lab Report in the form of abstracts

– very concise, based on lab data– Incorporate statistics– With revision and resubmission

• No separate lab tests; lab material included on lecture tests

GRADING• 3 lecture tests = 60%

– multiple multiple choice (choose all correct answers)– Some short answer in the space provided– Rarely fill in the blank– Sometime create or complete graph or diagram– discussion question(s) from a list

• Cumulative final exam = 20%• Other work = 20%

– Abstract = 10% – 1 Question Quizzes (1QQs) and other assignments = 10%

Honor Code

• All worked is “pledged.”• Issues of plagiarism to be handled by the

Honor Court.• Work together, but submit your own work.

ODDS AND ENDS

• Limited use of electronics in classroom & lab– Only for class/lab-related activities

• NO FOOD or DRINKS in Lab • BE ON TIME, READY TO GET TO WORK• DON’T ASK ABOUT LENGTH OF LAB• BE READY TO START ON TIME• RECORDING LECTURES BY PERMISSION WITH LIMITS

Study Questions & Quizzes

• Questions provided for each chapter (On the website!)

• Read the book and answer the questions PRIOR to class meeting

• Class time is used to deal with problematical topics and reinforce the major concepts

• Be ready for 1QQs

Study Questions & Quizzes

• Rationale for this format:– See what Dr. Davis thinks you ought to emphasize– Writing helps to consolidate memory and recall– Greater effort results in better retention and

understanding– Students are engaged learners– Able to cover more information

Improve MCAT, DCAT and GRE scores

Sample 1QQName on top edge, back side of paperAnswer on blank side of paper.

1.The 200+ cell types in the human body can be classified into one of 4 cell types or tissue types. List the 4 types and their distinguishing characteristics.

2.List the 4 modes of heat exchange and provide an example of one of those modes.

3.What is the difference between an organ and a tissue?

Cognitive Domain (Revised Bloom) Description    Action verbs        Original Bloom’s term

1.Remember (LOCS)**  Retrieve relevant knowledge   Recognize, identify, recall, list, label      Knowledge

2. Understand (LOCS)  Describe meaning    Interpret, exemplify, classify, summarize/explain/describe in own words    

Comprehension

3. Apply (LOCS/HOCS)  Use/apply procedures or info in novel context  Execute, predict         Application

4. Analyze (HOCS)  Infer relationships between components or parts and bigger picture Differentiate, organize, link, attribute, infer, interpret, diagnose, compare/contrast, conclude, speculate Analysis

5. Evaluate (HOCS)  Make judgments based on evidence, criteria, and standards Verify, critique, assess merit       Evaluation

6. Create (HOCS)   Piece together info to form novel whole; create original product Generate, plan, build, produce, design, model      Synthesis

A Taxonomy of Cognitive Skills for Developing Student Assignments and Assessments**SC SDE (Pat Mohr). Adapted from Lorin W. Anderson, David R. Krathwohl et al (Eds.) A Taxonomy for Learning, Teaching, and Assessing: A Revision of Bloom’s Taxonomy of Educational Objectives 2001; modified by Ellen Goldey, Wofford College, to incorporate “Biology in Bloom,” Crowe et al., 2008, CBE – Life Sci Edu., 7: 368-381. **HOCS = higher order cognitive skills, LOCS = lower order cognitive skills.

More stuff

• Arrive early for lecture and lab• Pay attention (no cell phones, email, Facebook, etc.

during lecture or lab)• Take notes on what is said….don’t wait for

boardwork.• Powerpoints usually posted AFTER lecture• Drop by the office for a visit!• Complete the Personal Information Sheet on the

Moodle site and submit it electronically to Moodle.

Chapter 1 and parts of 16

• Tissues• Organs• Organ Systems• Homeostasis• Negative & positive feedback, acclimation• Two detailed examples: Thermoregulation

and Glucose Homeostasis

Genetics & Development

Cell & Molecular

200

Histology

Name an organ and verify it has all 4 tissue types.

Figure 01.01cAnatomy

Cell types (page 1)

• Hepatocyte• Cardiac myofiber• Type II pneumocyte • Purkinje fiber (heart)• Erythrocyte• Enteroendocrine cell• Simple cuboidal cell of

the proximal renal tubule

• Principal cell of the thyroid gland

• Endothelial cell• Fibroblast• Osteocyte• Lactotroph• Acinar cell of pancreas• Beta cell of Islet of

Langerhans• Schwann cell

More cell types (page 2)

• Rod cell of the retina• Leydig cell• Hair cell of cochlea• Smooth myofiber of

arteriole• Mast cell• Unilocular adipocyte• Alpha motoneuron• Gamma motoneuron

• Retinal ganglion cell• Megakaryocyte• Satellite cell (ganglion)• Astrocyte• Dorsal root ganglion cell• Merkel cell• Myoepithelial cell of salivary

gland• Alpha cell of the Islet of

Langerhans

Even More Cell Types ( page 3)

• Parietal cell of stomach• Chief cell of stomach• Paneth cell• Podocyte• Juxtaglomerular cell• Cell of the macula

densa• Chromaffin cell of the

adrenal medulla

• Parafollicular cell of the thyroid

• Cell of the collecting duct in the kidney

• Secretory cell of the zona glomerulosa in adrenal cortex

• Secretory cell of the zonal fasciculata in adrenal cortex

The Human Body:A Society of Cells

• Imagine you are a cell. Ask yourself:• Which category of cell am I? (Epithelial, Connective, Nervous, or Muscle)• What are my special characteristics and functions that distinguish me from

all other cell types? (This is what makes me unique!) • What do I do for the person in whom I reside? What are my contributions

to the whole organism? To homeostasis? • What do I need to survive?• In what ways do I depend on other cells?• What governs my actions? • Where did I come from? How long will I live?• What would happen to the organism if I along with all the other cells of my

type were to fail to function properly?

Answer as many of the above questions as you can and provide your sources. Submit your essay to the Moodle Site by midnight Sunday, Sept 8.

Bring a printout to class on Monday, Sept 9th.

O2

Cell Membrane: selectively permeable

Capillaries: highly permeable except to proteins

Homeostasis:

• The relative constancy of the internal environment

• Steady state vs. equilibrium

BeggarThessaloniki, Greece

First section: the importance of temperture….. thermoregulation

Second second: the importance of fuel molecules …. Glucose homeostasis