“letthy%food%be%thy%medicine,%and%thy%medicine%be%thy%food.” ev... · 2015. 9. 25. · o red...
TRANSCRIPT
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Your Preferred Partner In Palm Nutraceutical Excellence
WH Leong, CEO, ExcelVite Sdn. Bhd.
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“Let thy food be thy medicine, and thy medicine be thy food.”
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Your Preferred Partner In Palm Nutraceutical Excellence
Red Palm Oil – The Most Nutritious Oil
• ExcelVite – Brief Introduction • Our Process and Products • About Red Palm Oil
§ Crown Jewels in Red Palm Oil • Challenges and Opportunities • EVSpectra™ Red Palm Oil Concentrate
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Your Preferred Partner In Palm Nutraceutical Excellence
Ø 1994 – Formerly known as Carotech. First & only integrated plant in the world to commercially extract tocotrienols (“Super Vitamin E”) and mixed carotene, from crude palm oil (Elaeis guineensis)
Ø Protected by US Patents and scientifically-substantiated with human clinical studies (flagship product : Tocotrienols)
Ø 2007 – the only GMP-certified tocotrienol producer in the world
Ø 2012 – the only FDA-inspected tocotrienol producer in the world
Ø Current leading & largest producer of tocotrienol and mixed carotene in the world
Ø Experienced and proven management (20 years)
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Your Preferred Partner In Palm Nutraceutical Excellence
Virgin Crude Palm Oil
(Elaeis guineensis)
Extrac?on & Reac?on Process
Molecular Dis?lla?on (Ultra-‐High Vacuum / Low Temperature)
Biodiesel -‐ Oleochemical &
Glycerine
Full Spectrum Palm Tocotrienol / Tocopherol
Complex
Palm Mixed Carotene Complex
Palm Phytosterol Complex
Red Palm Oil Concentrate
• Dietary Supplements / Pharmaceu?cals • Food & Drink • Cosme?c, Personal Care Products
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Your Preferred Partner In Palm Nutraceutical Excellence
Palm Tree Palm Fruits Virgin Red Palm Oil
& 1. EVNol™ - Natural Full Spectrum Tocotrienol Complex
2. EVNol SupraBio™ – Bioenhanced Natural Full Spectrum Tocotrienol Complex
3. EVTene™ - Natural Mixed-Carotenes Complex
4. EVRol™ - Naturel Phytosterol Complex
5. EVSpectra™ - Natural Red Palm Oil Concentrate
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Your Preferred Partner In Palm Nutraceutical Excellence
Malaysian Red Palm Oil o The oil palm (Elaeis guineensis) originates from
West Africa o Has not been genetically-modified (NON-GMO) o Red Palm Oil naturally contains high levels of
valuable minor constituents:
Tocotrienols + Tocopherol (600 – 1000ppm)
Carotenoids (500 – 700 ppm)
Phytosterols (326 – 527 ppm)
Squalene (200 – 500 ppm)
Phospholipids (5 – 130 ppm)
Without these valuable minor constituents, Red Palm Oil will just be another ordinary cooking oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Malaysian Red Palm Oil
Tocotrienol
• Belongs to the vitamin E family
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Carotenoids (Alpha Carotene & Beta Carotene)
• Pro-Vitamin A
The Crown Jewels of Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Malaysian Red Palm Oil
Tocotrienol
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1st Crown Jewel of Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Ø There are 8 forms of natural vitamin E Tocopherols (Major source : Soybean) Tocotrienols (Major source : Palm)
Ø All published papers on vitamin E (35,354) listed in PubMed – Less than 1% related to tocotrienol ! (Source: PubMed)
R1
R1
R2
R2 Methyl Group R1 R2
Alpha-‐ CH3 CH3
Beta-‐ CH3 H
Gamma-‐ H CH3
Delta-‐ H H
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Your Preferred Partner In Palm Nutraceutical Excellence
Methyl Group R1 R2
Alpha- CH3 CH3
Beta- CH3 H
Gamma- H CH3
Delta- H H TOCOPHEROL (T)
TOCOTRIENOL (T3)
HO R1
R2 CH3
CH3
HO R1
R2
There are 8 forms of natural vitamin E : Tocopherols (Major source : Soybean) Tocotrienols (Major source : Palm)
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Your Preferred Partner In Palm Nutraceutical Excellence
Malaysian Red Palm Oil
Vitamin E Composition in Red Palm Oil - 78% mixed tocotrienols (α,β,γ,δ) - 22% α-tocopherol
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Your Preferred Partner In Palm Nutraceutical Excellence
Human Clinical Studies
Cancer Research
(Breast Cancer / Prostate Cancer)
Heart Health (Carotid stenosis /
Cholesterol Health / Arterial
Compliance)
Skin Nutrition
(Super antioxidant / anti-
aging / scar reduction /
accumulation in skin)
Neuro Protection (Brain Health -
Stroke/ Cognition / Alzheimer’s Disease /
White Matter Lesions)
Liver Health
(NAFLD / Liver Stiffness / Metabolic Syndrome)
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Ø Total published papers on vitamin E (35,354) listed in PubMed – Less than 1% related to tocotrienol ! (Source: PubMed)
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Your Preferred Partner In Palm Nutraceutical Excellence
71 120
12 27 27
243
672
0
100
200
300
400
500
600
700
800
Brain Health Heart Health Liver Health Skin Health Radiation Cancer Others
Num
ber
of p
aper
s
Indications
Number of Published Research Papers (Pubmed, total on tocotrienols = 1172 as at 22 July 2015)
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Your Preferred Partner In Palm Nutraceutical Excellence
B r a i n H e a l t h • Non-antioxidant property – regulate key checkpoints to minimize neuronal cell degeneration and death; induces arteriogenesis and increases secondary blood supply to stroke-affected area. • Via Antioxidant property.
H e a r t H e a l t h • Regulates down-degradation of HMG CoA-Reductase • Potent antioxidant property
L i v e r H e a l t h • Anti-inflammatory function.
S k i n H e a l t h • Antioxidant, anti-aging, anti-inflammatory functions
C a n c e r • Growth arrests, antiproliferative and apoptotic effects.
• Suppression of carcinogenesis. • Potent antioxidant property – free radical scavenging
R a d i a t i o n P r o t e c t i o n • Potent antioxidant activity (ROS and RNS scavenging)
• Growth arrests, antiproliferative and apoptotic effects.
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Your Preferred Partner In Palm Nutraceutical Excellence
Malaysian Red Palm Oil
Carotenoids
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2nd Crown Jewel of Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Distribution of Carotenes in Carrot & Red Palm Oil
32% α-Carotene
β-Carotene
Others
63%
5%
34%
60%
6%
< 100 ppm 500 – 700 ppm
• Carotenoid composition of red palm oil is similar to carrots • > 60% beta-carotene and >30% alpha-carotene • Including other natural carotenoids (gamma carotene & lycopene)
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Your Preferred Partner In Palm Nutraceutical Excellence
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Comparison of Various Sources of Carotene
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Your Preferred Partner In Palm Nutraceutical Excellence
Alpha-, and Beta-Carotene Total Publications : ~ 13,712 Nutrition
Heart Health Skin
Cancer
Animal Health
Papers ~2606
Papers ~427
Papers ~3,050
Papers ~525
Papers ~1139
All papers on “Carotenoids” =
71,912 (as at 28 July
2015)
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Your Preferred Partner In Palm Nutraceutical Excellence
Malaysian Red Palm Oil
Today, RPO is harvested from 3 main regions:
Peninsular Malaysia
Borneo
Indonesia
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Your Preferred Partner In Palm Nutraceutical Excellence
Challenges • Sustainability
? Environmental impact ? Wild life losing habitat ? Is Malaysian Red Palm Oil sustainably produced
• Peninsular Malaysia ü Existing Crop Land > 25 years ü > 50% forest cover ü Plantations and Smallholders – RSPO members ü Governed by Stringent Rules & Regulations – Monitored by MPOB Enforcers
• Other regions ? Sustainability Policies Not Well Defined
• Negative studies on vitamin E (alpha-tocopherol) and beta-carotene – mainly synthetic or single isoform
Malaysian Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Opportunities ü Red Palm Oil has more vitamin E and carotenes than any
other vegetable oils • Olive, corn, sunflower, safflower oils do not contain carotenoids • Vitamin E (tocotrienols + tocopherol) content in Red Palm Oil is
significantly higher than all these other oils • Red Palm Oil is also significantly higher in Vitamin E content
compared with vegetable sources of vitamin E
ü Red Palm Oil has the highest Retinol Equivalents (RE) compared to carrots (15x), leafy vegetables (44x), apricots (120x), tomatoes (300x), bananas (1000x), and orange juice (3750x).
Malaysian Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Opportunities ü Improves nutritional value of end products – possible for
RDA claims on products ü Boosts nutritional content with all the naturally existing
minor components ü Availability of published research studies in the area of
vitamin A deficiency, heart disease, and cancer
Food manufacturers are eliminating the use of synthetic colors (Southampton Study) – Red Palm Oil fits right into
the latest “Coloring Food with Food” trend
Malaysian Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Red Palm Oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Opportunities – Red Palm Tocotrienols
2012 $290m
2015 $376m
é 29.6%
Ø Market value of natural vitamin E (ingredient / raw mat) (Source: Frost & Sullivan)
Huge Opportunities for tocotrienols as the “Super Vitamin E”
Ø Large body of science demonstrated efficacy of red palm tocotrienols (EVNol™ and EVNol SupraBio™) in health areas covering brain, heart, liver, skin & hair.
Ø Clinical studies show red palm tocotrienols are bioavailable and bioefficient.
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Your Preferred Partner In Palm Nutraceutical Excellence
Opportunities – Palm Carotenoids
2014 $306m
2020 $446m
é 45.8%
Ø Market value of natural coloring market (Source: Future Market Insights)
Ø Growing demand for natural food colorings by manufacturers and consumers
Ø Alpha- and beta-carotenes are precursors of vitamin A Ø Apart from imparting color to foods, palm carotenoids provide
essential nutritional benefits to children and women in terms of overcoming vitamin A deficiency, as well as improving the immune system.
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Your Preferred Partner In Palm Nutraceutical Excellence
Strictly Private & Confiden3al
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Your Preferred Partner In Palm Nutraceutical Excellence
EVSpectra™ - Red Palm Oil Concentrate
Ø Launched in response to demand from the dietary supplement industry. Ø EVSpectra™ allows manufacturers to offer all the goodness and benefits of
red palm oil in a softgel dosage form ü Convenience ü Lower oil (triglyceride) intake, hence reduced calorie
Ø EVSpectra™ is 100 times more concentrated than red palm oil Ø Provides phytonutrients tocotrienol and carotenoids of 2 tablespoon (28g)
or red palm oil in one 250mg softgel capsule
Ø The ratio of total vitamin E to total mixed carotenoids is 2:1 – exactly the same as found in red palm oil
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Your Preferred Partner In Palm Nutraceutical Excellence
Corporate Website
www.excelvite.com
Tocotrienol Educational Website
www.tocotrienol.org
Your Preferred Partner In Palm Nutraceutical Excellence
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Your Preferred Partner In Palm Nutraceutical Excellence
GMP Manufacturing Facility : ExcelVite Sdn. Bhd. Lot 56442, 7 ½ Mile, Jalan Ipoh/Chemor, 31200 Chemor, Perak, Malaysia U.S. Sales Office: ExcelVite Inc. 21, Balmoral Court, 08817 Edison, New Jersey [email protected] Australia : [email protected] General Enquiries: [email protected] www.excelvite.com www.tocotrienol.org
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Your Preferred Partner In Palm Nutraceutical Excellence
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